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Phenotypic and microRNA characterisation of the neglected CD24+ cell population in MCF-7 breast cancer 3D spheroid culture.

Boo L, Yeap SK, Ali NM, Ho WY, Ky H, Satharasinghe DA, Liew WC, Tan SW, Wang ML, Cheong SK, Ong HK.

J Chin Med Assoc. 2019 Nov 15. doi: 10.1097/JCMA.0000000000000226. [Epub ahead of print]


Bromelain Enhances the Anti-tumor Effects of Cisplatin on 4T1 Breast Tumor Model In Vivo.

Mohamad NE, Abu N, Yeap SK, Alitheen NB.

Integr Cancer Ther. 2019 Jan-Dec;18:1534735419880258. doi: 10.1177/1534735419880258.


Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast Cancer.

Mohamed Amin Z, Che Ani MA, Tan SW, Yeap SK, Alitheen NB, Syed Najmuddin SUF, Kalyanasundram J, Chan SC, Veerakumarasivam A, Chia SL, Yusoff K.

Sci Rep. 2019 Sep 30;9(1):13999. doi: 10.1038/s41598-019-50222-z.


In Vivo Anti-Tumor Effects of Citral on 4T1 Breast Cancer Cells via Induction of Apoptosis and Downregulation of Aldehyde Dehydrogenase Activity.

Nigjeh SE, Yeap SK, Nordin N, Rahman H, Rosli R.

Molecules. 2019 Sep 5;24(18). pii: E3241. doi: 10.3390/molecules24183241.


An Influenza A Vaccine Based on the Extracellular Domain of Matrix 2 Protein Protects BALB/C Mice Against H1N1 and H3N2.

Ong HK, Yong CY, Tan WS, Yeap SK, Omar AR, Razak MA, Ho KL.

Vaccines (Basel). 2019 Aug 19;7(3). pii: E91. doi: 10.3390/vaccines7030091.


Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus.

Yong CY, Ong HK, Yeap SK, Ho KL, Tan WS.

Front Microbiol. 2019 Aug 2;10:1781. doi: 10.3389/fmicb.2019.01781. eCollection 2019. Review.


Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells in vitro and in vivo.

Mohamad NE, Abu N, Yeap SK, Lim KL, Romli MF, Sharifuddin SA, Long K, Alitheen NB.

Nutr Metab (Lond). 2019 Jul 26;16:49. doi: 10.1186/s12986-019-0380-5. eCollection 2019.


Infectious hematopoietic necrosis virus: advances in diagnosis and vaccine development.

Yong CY, Ong HK, Tang HC, Yeap SK, Omar AR, Ho KL, Tan WS.

PeerJ. 2019 Jul 16;7:e7151. doi: 10.7717/peerj.7151. eCollection 2019.


Preparation and Characterization of Self Nano-Emulsifying Drug Delivery System Loaded with Citraland Its Antiproliferative Effect on Colorectal Cells In Vitro.

Mohd Izham MN, Hussin Y, Aziz MNM, Yeap SK, Rahman HS, Masarudin MJ, Mohamad NE, Abdullah R, Alitheen NB.

Nanomaterials (Basel). 2019 Jul 18;9(7). pii: E1028. doi: 10.3390/nano9071028.


Isolation and Characterization of Lactobacillus spp. from Kefir Samples in Malaysia.

Talib N, Mohamad NE, Yeap SK, Hussin Y, Aziz MNM, Masarudin MJ, Sharifuddin SA, Hui YW, Ho CL, Alitheen NB.

Molecules. 2019 Jul 17;24(14). pii: E2606. doi: 10.3390/molecules24142606.


Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927.

Labadie SS, Li J, Blake RA, Chang JH, Goodacre S, Hartman SJ, Liang W, Kiefer JR, Kleinheinz T, Lai T, Liao J, Ortwine DF, Mody V, Ray NC, Roussel F, Vinogradova M, Yeap SK, Zhang B, Zheng X, Zbieg JR, Liang J, Wang X.

Bioorg Med Chem Lett. 2019 Aug 15;29(16):2090-2093. doi: 10.1016/j.bmcl.2019.07.013. Epub 2019 Jul 6.


Quantitative Proteomics Analysis Revealed Compromised Chicken Dendritic Cells Function at Early Stage of Very Virulent Infectious Bursal Disease Virus Infection.

Yasmin AR, Omar AR, Farhanah MI, Hiscox AJ, Yeap SK.

Avian Dis. 2019 Jun 1;63(2):275-288. doi: 10.1637/11936-072418-Reg.1.


Postbiotic metabolites produced by Lactobacillus plantarum strains exert selective cytotoxicity effects on cancer cells.

Chuah LO, Foo HL, Loh TC, Mohammed Alitheen NB, Yeap SK, Abdul Mutalib NE, Abdul Rahim R, Yusoff K.

BMC Complement Altern Med. 2019 Jun 3;19(1):114. doi: 10.1186/s12906-019-2528-2.


In vitro and in vivo antitumour effects of coconut water vinegar on 4T1 breast cancer cells.

Mohamad NE, Yeap SK, Abu N, Lim KL, Zamberi NR, Nordin N, Sharifuddin SA, Long K, Alitheen NB.

Food Nutr Res. 2019 Jan 10;63. doi: 10.29219/fnr.v63.1616. eCollection 2019.


In vitro cytotoxicity and anticancer effects of citral nanostructured lipid carrier on MDA MBA-231 human breast cancer cells.

Nordin N, Yeap SK, Rahman HS, Zamberi NR, Abu N, Mohamad NE, How CW, Masarudin MJ, Abdullah R, Alitheen NB.

Sci Rep. 2019 Feb 7;9(1):1614. doi: 10.1038/s41598-018-38214-x.


Cytotoxicity of eupatorin in MCF-7 and MDA-MB-231 human breast cancer cells via cell cycle arrest, anti-angiogenesis and induction of apoptosis.

Razak NA, Abu N, Ho WY, Zamberi NR, Tan SW, Alitheen NB, Long K, Yeap SK.

Sci Rep. 2019 Feb 6;9(1):1514. doi: 10.1038/s41598-018-37796-w.


Targeted inactivation of Salmonella Agona metabolic genes by group II introns and in vivo assessment of pathogenicity and anti-tumour activity in mouse model.

Gwee CP, Khoo CH, Yeap SK, Tan GC, Cheah YK.

PeerJ. 2019 Jan 16;7:e5989. doi: 10.7717/peerj.5989. eCollection 2019.


RNA sequencing of kidney and liver transcriptome obtained from wild cynomolgus macaque (Macaca fascicularis) originating from Peninsular Malaysia.

Ee Uli J, Yong CS, Yeap SK, Alitheen NB, Rovie-Ryan JJ, Mat Isa N, Tan SG.

BMC Res Notes. 2018 Dec 22;11(1):923. doi: 10.1186/s13104-018-4014-1.


Comparative Pathogenicity of Malaysian QX-like and Variant Infectious Bronchitis Virus Strains in Chickens at Different Age of Exposure to the Viruses.

Khanh NP, Tan SW, Yeap SK, Lee HJ, Choi KS, Hair-Bejo M, Bich TN, Omar AR.

J Comp Pathol. 2018 May;161:43-54. doi: 10.1016/j.jcpa.2018.04.006. Epub 2018 Jun 1.


Phytochemical composition and in vitro antioxidant activities of Citrus sinensis peel extracts.

Liew SS, Ho WY, Yeap SK, Sharifudin SAB.

PeerJ. 2018 Aug 3;6:e5331. doi: 10.7717/peerj.5331. eCollection 2018.


Effects of Newcastle Disease Virus Infection on Chicken Intestinal Intraepithelial Natural Killer Cells.

Abdolmaleki M, Yeap SK, Tan SW, Satharasinghe DA, Bello MB, Jahromi MZ, Bejo MH, Omar AR, Ideris A.

Front Immunol. 2018 Jun 20;9:1386. doi: 10.3389/fimmu.2018.01386. eCollection 2018.


Coconut water vinegar ameliorates recovery of acetaminophen induced liver damage in mice.

Mohamad NE, Yeap SK, Beh BK, Ky H, Lim KL, Ho WY, Sharifuddin SA, Long K, Alitheen NB.

BMC Complement Altern Med. 2018 Jun 25;18(1):195. doi: 10.1186/s12906-018-2199-4.


Differential activation of intraepithelial lymphocyte-natural killer cells in chickens infected with very virulent and vaccine strains of infectious bursal disease virus.

Jahromi MZ, Bello MB, Abdolmaleki M, Yeap SK, Hair-Bejo M, Omar AR.

Dev Comp Immunol. 2018 Oct;87:116-123. doi: 10.1016/j.dci.2018.06.004. Epub 2018 Jun 7.


Antihyperglycemic and anti-inflammatory effects of fermented food paste in high-fat diet and streptozotocin-challenged mice.

Zulkawi N, Ng KH, Zamberi NR, Yeap SK, Satharasinghe DA, Tan SW, Ho WY, Abd Rashid NY, Md Lazim MI, Jamaluddin A, Alitheen NB, Long K.

Drug Des Devel Ther. 2018 May 23;12:1373-1383. doi: 10.2147/DDDT.S157803. eCollection 2018.


DK1 Induces Apoptosis via Mitochondria-Dependent Signaling Pathway in Human Colon Carcinoma Cell Lines In Vitro.

Hussin Y, Aziz MNM, Che Rahim NF, Yeap SK, Mohamad NE, Masarudin MJ, Nordin N, Abd Rahman NMA, Yong CY, Akhtar MN, Zamrus SNH, Alitheen NB.

Int J Mol Sci. 2018 Apr 11;19(4). pii: E1151. doi: 10.3390/ijms19041151.


Bursal immunopathology responses of specific-pathogen-free chickens and red jungle fowl infected with very virulent infectious bursal disease virus.

Farhanah MI, Yasmin AR, Khanh NP, Yeap SK, Hair-Bejo M, Omar AR.

Arch Virol. 2018 Aug;163(8):2085-2097. doi: 10.1007/s00705-018-3841-7. Epub 2018 Apr 6.


Design, synthesis and cytotoxic effects of curcuminoids on HeLa, K562, MCF-7 and MDA-MB-231 cancer cell lines.

Zamrus SNH, Akhtar MN, Yeap SK, Quah CK, Loh WS, Alitheen NB, Zareen S, Tajuddin SN, Hussin Y, Shah SAA.

Chem Cent J. 2018 Mar 19;12(1):31. doi: 10.1186/s13065-018-0398-1.


Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines.

Abu Bakar A, Akhtar MN, Mohd Ali N, Yeap SK, Quah CK, Loh WS, Alitheen NB, Zareen S, Ul-Haq Z, Shah SAA.

Molecules. 2018 Mar 8;23(3). pii: E616. doi: 10.3390/molecules23030616.


Genetic variation and DNA fingerprinting of durian types in Malaysia using simple sequence repeat (SSR) markers.

Siew GY, Ng WL, Tan SW, Alitheen NB, Tan SG, Yeap SK.

PeerJ. 2018 Mar 2;6:e4266. doi: 10.7717/peerj.4266. eCollection 2018.


Citral induced apoptosis in MDA-MB-231 spheroid cells.

Nigjeh SE, Yeap SK, Nordin N, Kamalideghan B, Ky H, Rosli R.

BMC Complement Altern Med. 2018 Feb 13;18(1):56. doi: 10.1186/s12906-018-2115-y.


Subchronic toxicity, immunoregulation and anti-breast tumor effect of Nordamnacantal, an anthraquinone extracted from the stems of Morinda citrifolia L.

Abu N, Zamberi NR, Yeap SK, Nordin N, Mohamad NE, Romli MF, Rasol NE, Subramani T, Ismail NH, Alitheen NB.

BMC Complement Altern Med. 2018 Jan 27;18(1):31. doi: 10.1186/s12906-018-2102-3.


Molecular Characterization of QX-Like and Variant Infectious Bronchitis Virus Strains in Malaysia Based on Partial Genomic Sequences Comprising the S-3a/3b-E-M-Intergenic Region-5a/5b-N Gene Order.

Khanh NP, Tan SW, Yeap SK, Satharasinghe DA, Hair-Bejo M, Bich TN, Omar AR.

Avian Dis. 2017 Dec;61(4):442-452. doi: 10.1637/11637-032817-Reg.1.


Corrigendum to "Safety and Clinical Usage of Newcastle Disease Virus in Cancer Therapy".

Lam HY, Yeap SK, Pirozyan MR, Omar AR, Yusoff K, Abd-Aziz S, Alitheen NB.

Biomed Res Int. 2017;2017:4529437. doi: 10.1155/2017/4529437. Epub 2017 Dec 3.


Characterization and toxicity of citral incorporated with nanostructured lipid carrier.

Nordin N, Yeap SK, Zamberi NR, Abu N, Mohamad NE, Rahman HS, How CW, Masarudin MJ, Abdullah R, Alitheen NB.

PeerJ. 2018 Jan 4;6:e3916. doi: 10.7717/peerj.3916. eCollection 2018.


Curcumin Analog DK1 Induces Apoptosis in Human Osteosarcoma Cells In Vitro through Mitochondria-Dependent Signaling Pathway.

Aziz MNM, Hussin Y, Che Rahim NF, Nordin N, Mohamad NE, Yeap SK, Yong CY, Masarudin MJ, Cheah YK, Abu N, Akhtar MN, Alitheen NB.

Molecules. 2018 Jan 5;23(1). pii: E75. doi: 10.3390/molecules23010075.


Induction of a robust immune response against avian influenza virus following transdermal inoculation with H5-DNA vaccine formulated in modified dendrimer-based delivery system in mouse model.

Bahadoran A, Ebrahimi M, Yeap SK, Safi N, Moeini H, Hair-Bejo M, Hussein MZ, Omar AR.

Int J Nanomedicine. 2017 Nov 30;12:8573-8585. doi: 10.2147/IJN.S139126. eCollection 2017.


Dietary coconut water vinegar for improvement of obesity-associated inflammation in high-fat-diet-treated mice.

Mohamad NE, Yeap SK, Ky H, Ho WY, Boo SY, Chua J, Beh BK, Sharifuddin SA, Long K, Alitheen NB.

Food Nutr Res. 2017 Sep 21;61(1):1368322. doi: 10.1080/16546628.2017.1368322. eCollection 2017.


Advances in the study of nodavirus.

Yong CY, Yeap SK, Omar AR, Tan WS.

PeerJ. 2017 Sep 27;5:e3841. doi: 10.7717/peerj.3841. eCollection 2017.


RNA sequencing (RNA-Seq) of lymph node, spleen, and thymus transcriptome from wild Peninsular Malaysian cynomolgus macaque (Macaca fascicularis).

Ee Uli J, Yong CSY, Yeap SK, Rovie-Ryan JJ, Mat Isa N, Tan SG, Alitheen NB.

PeerJ. 2017 Aug 17;5:e3566. doi: 10.7717/peerj.3566. eCollection 2017.


The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells.

Etti IC, Abdullah R, Kadir A, Hashim NM, Yeap SK, Imam MU, Ramli F, Malami I, Lam KL, Etti U, Waziri P, Rahman M.

PLoS One. 2017 Aug 3;12(8):e0182357. doi: 10.1371/journal.pone.0182357. eCollection 2017.


Anti-obesity and anti-inflammatory effects of synthetic acetic acid vinegar and Nipa vinegar on high-fat-diet-induced obese mice.

Beh BK, Mohamad NE, Yeap SK, Ky H, Boo SY, Chua JYH, Tan SW, Ho WY, Sharifuddin SA, Long K, Alitheen NB.

Sci Rep. 2017 Jul 27;7(1):6664. doi: 10.1038/s41598-017-06235-7.


Phenotypic and microRNA transcriptomic profiling of the MDA-MB-231 spheroid-enriched CSCs with comparison of MCF-7 microRNA profiling dataset.

Boo L, Ho WY, Mohd Ali N, Yeap SK, Ky H, Chan KG, Yin WF, Satharasinghe DA, Liew WC, Tan SW, Cheong SK, Ong HK.

PeerJ. 2017 Jul 13;5:e3551. doi: 10.7717/peerj.3551. eCollection 2017.


In vitro characterization and in vivo toxicity, antioxidant and immunomodulatory effect of fermented foods; Xeniji™.

Zulkawi N, Ng KH, Zamberi R, Yeap SK, Satharasinghe D, Jaganath IB, Jamaluddin AB, Tan SW, Ho WY, Alitheen NB, Long K.

BMC Complement Altern Med. 2017 Jun 30;17(1):344. doi: 10.1186/s12906-017-1845-6.


The effects of different velogenic NDV infections on the chicken bursa of Fabricius.

Kristeen-Teo YW, Yeap SK, Tan SW, Omar AR, Ideris A, Tan SG, Alitheen NB.

BMC Vet Res. 2017 May 31;13(1):151. doi: 10.1186/s12917-017-1071-y.


Characterisation of sol-gel method synthesised MgZnFe2O4 nanoparticles and its cytotoxic effects on breast cancer cell line, MDA MB-231 in vitro.

Nordin N, Kanagesan S, Zamberi NR, Yeap SK, Abu N, Tamilselvan S, Hashim M, Alitheen NB.

IET Nanobiotechnol. 2017 Apr;11(3):343-348. doi: 10.1049/iet-nbt.2016.0007.


Susceptibility of Human Oral Squamous Cell Carcinoma (OSCC) H103 and H376 cell lines to Retroviral OSKM mediated reprogramming.

Verusingam ND, Yeap SK, Ky H, Paterson IC, Khoo SP, Cheong SK, Ong AHK, Kamarul T.

PeerJ. 2017 Apr 13;5:e3174. doi: 10.7717/peerj.3174. eCollection 2017.


Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells.

Etti IC, Rasedee A, Hashim NM, Abdul AB, Kadir A, Yeap SK, Waziri P, Malami I, Lim KL, Etti CJ.

Drug Des Devel Ther. 2017 Mar 20;11:865-879. doi: 10.2147/DDDT.S124324. eCollection 2017.


Correction: Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells.

Malami I, Abdul AB, Abdullah R, Kassim NK, Rosli R, Yeap SK, Waziri P, Etti IC, Bello MB.

PLoS One. 2017 Mar 7;12(3):e0173651. doi: 10.1371/journal.pone.0173651. eCollection 2017.


Synthetic curcumin derivative DK1 possessed G2/M arrest and induced apoptosis through accumulation of intracellular ROS in MCF-7 breast cancer cells.

Ali NM, Yeap SK, Abu N, Lim KL, Ky H, Pauzi AZM, Ho WY, Tan SW, Alan-Ong HK, Zareen S, Alitheen NB, Akhtar MN.

Cancer Cell Int. 2017 Feb 21;17:30. doi: 10.1186/s12935-017-0400-3. eCollection 2017.

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