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Items: 1 to 50 of 197

1.

AntimiR-155 Cyclic Peptide-PNA Conjugate: Synthesis, Cellular Uptake, and Biological Activity.

Soudah T, Khawaled S, Aqeilan RI, Yavin E.

ACS Omega. 2019 Aug 12;4(9):13954-13961. doi: 10.1021/acsomega.9b01697. eCollection 2019 Aug 27.

2.

Red-emitting FIT-PNAs: "On site" detection of RNA biomarkers in fresh human cancer tissues.

Hashoul D, Shapira R, Falchenko M, Tepper O, Paviov V, Nissan A, Yavin E.

Biosens Bioelectron. 2019 Jul 15;137:271-278. doi: 10.1016/j.bios.2019.04.056. Epub 2019 May 8.

PMID:
31121464
3.

MiR-16-1-3p and miR-16-2-3p possess strong tumor suppressive and antimetastatic properties in osteosarcoma.

Maximov VV, Akkawi R, Khawaled S, Salah Z, Jaber L, Barhoum A, Or O, Galasso M, Kurek KC, Yavin E, Aqeilan RI.

Int J Cancer. 2019 Dec 1;145(11):3052-3063. doi: 10.1002/ijc.32368. Epub 2019 May 9.

PMID:
31018244
4.

Specific inhibition of splicing factor activity by decoy RNA oligonucleotides.

Denichenko P, Mogilevsky M, Cléry A, Welte T, Biran J, Shimshon O, Barnabas GD, Danan-Gotthold M, Kumar S, Yavin E, Levanon EY, Allain FH, Geiger T, Levkowitz G, Karni R.

Nat Commun. 2019 Apr 8;10(1):1590. doi: 10.1038/s41467-019-09523-0.

5.

Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment.

Mogilevsky M, Shimshon O, Kumar S, Mogilevsky A, Keshet E, Yavin E, Heyd F, Karni R.

Nucleic Acids Res. 2018 Nov 30;46(21):11396-11404. doi: 10.1093/nar/gky921.

6.

Predictive Model for the Sequence-Dependent Fluorogenic Response of Forced-Intercalation Peptide Nucleic Acid.

Peled I, Yavin E.

ACS Omega. 2018 Apr 30;3(4):3813-3818. doi: 10.1021/acsomega.8b00184. Epub 2018 Apr 4.

7.

Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma.

Tiram G, Ferber S, Ofek P, Eldar-Boock A, Ben-Shushan D, Yeini E, Krivitsky A, Blatt R, Almog N, Henkin J, Amsalem O, Yavin E, Cohen G, Lazarovici P, Lee JS, Ruppin E, Milyavsky M, Grossman R, Ram Z, Calderón M, Haag R, Satchi-Fainaro R.

FASEB J. 2018 Jun 1:fj201701568R. doi: 10.1096/fj.201701568R. [Epub ahead of print]

PMID:
29856660
8.

Protein Regulation by Intrinsically Disordered Regions: A Role for Subdomains in the IDR of the HIV-1 Rev Protein.

Faust O, Grunhaus D, Shimshon O, Yavin E, Friedler A.

Chembiochem. 2018 Aug 6;19(15):1618-1624. doi: 10.1002/cbic.201800192. Epub 2018 Jun 28.

PMID:
29791766
9.

Neuroprotective Effects of Bioactive Compounds and MAPK Pathway Modulation in "Ischemia"-Stressed PC12 Pheochromocytoma Cells.

Lahiani A, Brand-Yavin A, Yavin E, Lazarovici P.

Brain Sci. 2018 Feb 8;8(2). pii: E32. doi: 10.3390/brainsci8020032. Review.

10.

CLIP6-PNA-Peptide Conjugates: Non-Endosomal Delivery of Splice Switching Oligonucleotides.

Soudah T, Mogilevsky M, Karni R, Yavin E.

Bioconjug Chem. 2017 Dec 20;28(12):3036-3042. doi: 10.1021/acs.bioconjchem.7b00638. Epub 2017 Dec 6.

PMID:
29211451
11.

The Molecular Basis of Toxins' Interactions with Intracellular Signaling via Discrete Portals.

Lahiani A, Yavin E, Lazarovici P.

Toxins (Basel). 2017 Mar 16;9(3). pii: E107. doi: 10.3390/toxins9030107. Review.

12.

Novel Synthetic PEGylated Conjugate of α-Lipoic Acid and Tempol Reduces Cell Death in a Neuronal PC12 Clonal Line Subjected to Ischemia.

Lahiani A, Hidmi A, Katzhendler J, Yavin E, Lazarovici P.

ACS Chem Neurosci. 2016 Oct 19;7(10):1452-1462. Epub 2016 Aug 22.

PMID:
27499112
13.

The effect of linker type and recognition peptide conjugation chemistry on tissue affinity and cytotoxicity of charged polyacrylamide.

Bloch MBD, Yavin E, Nissan A, Ariel I, Kenett R, Brass D, Rubinstein A.

J Control Release. 2017 Jul 10;257:102-117. doi: 10.1016/j.jconrel.2016.06.038. Epub 2016 Jun 30.

PMID:
27374628
14.

Solid nano-in-nanoparticles for potential delivery of siRNA.

Amsalem O, Nassar T, Benhamron S, Lazarovici P, Benita S, Yavin E.

J Control Release. 2017 Jul 10;257:144-155. doi: 10.1016/j.jconrel.2016.05.043. Epub 2016 May 20.

PMID:
27215702
15.

Single point mutation detection in living cancer cells by far-red emitting PNA-FIT probes.

Kolevzon N, Hashoul D, Naik S, Rubinstein A, Yavin E.

Chem Commun (Camb). 2016 Feb 7;52(11):2405-7. doi: 10.1039/c5cc07502e.

PMID:
26735489
16.

Postsynthetic conjugation of RNA to carboxylate and dicarboxylate molecules.

Shemesh Y, Yavin E.

Nucleosides Nucleotides Nucleic Acids. 2015;34(11):753-62. doi: 10.1080/15257770.2015.1073299. Epub 2015 Sep 30.

PMID:
26422297
17.

PNA-Rose Bengal Conjugates as Efficient DNA Photomodulators.

Shemesh Y, Yavin E.

Bioconjug Chem. 2015 Sep 16;26(9):1916-22. doi: 10.1021/acs.bioconjchem.5b00406. Epub 2015 Aug 18.

PMID:
26263421
18.

Antisense long noncoding RNAs regulate var gene activation in the malaria parasite Plasmodium falciparum.

Amit-Avraham I, Pozner G, Eshar S, Fastman Y, Kolevzon N, Yavin E, Dzikowski R.

Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):E982-91. doi: 10.1073/pnas.1420855112. Epub 2015 Feb 17.

19.

On the stability of Pt(IV) pro-drugs with haloacetato ligands in the axial positions.

Wexselblatt E, Raveendran R, Salameh S, Friedman-Ezra A, Yavin E, Gibson D.

Chemistry. 2015 Feb 9;21(7):3108-14. doi: 10.1002/chem.201405467. Epub 2014 Dec 21.

PMID:
25529335
20.

Human placental eXpanded (PLX) mesenchymal-like adherent stromal cells confer neuroprotection to nerve growth factor (NGF)-differentiated PC12 cells exposed to ischemia by secretion of IL-6 and VEGF.

Lahiani A, Zahavi E, Netzer N, Ofir R, Pinzur L, Raveh S, Arien-Zakay H, Yavin E, Lazarovici P.

Biochim Biophys Acta. 2015 Feb;1853(2):422-30. doi: 10.1016/j.bbamcr.2014.11.009. Epub 2014 Nov 15.

21.

Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.

Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M.

Epilepsia. 2014 Dec;55(12):1944-52. doi: 10.1111/epi.12857. Epub 2014 Nov 29.

22.

Multi-modal detection of colon malignancy by NIR-tagged recognition polymers and ultrasound contrast agents.

Bloch M, Jablonowski L, Yavin E, Moradov D, Djavsarov I, Nyska A, Wheatley M, Rubinstein A.

Int J Pharm. 2015 Jan 30;478(2):504-16. doi: 10.1016/j.ijpharm.2014.11.066. Epub 2014 Nov 28.

PMID:
25437110
23.

Synthesis and evaluation of a photoresponsive quencher for fluorescent hybridization probes.

Kovaliov M, Wachtel C, Yavin E, Fischer B.

Org Biomol Chem. 2014 Oct 21;12(39):7844-58. doi: 10.1039/c4ob01185f. Epub 2014 Sep 1.

PMID:
25177827
24.

Metabolic conversion of intra-amniotically-injected deuterium-labeled essential fatty acids by fetal rats following maternal n-3 fatty acid deficiency.

Yavin E, Lin YH, Brand A, Salem N Jr.

Biochim Biophys Acta. 2014 Sep;1841(9):1336-44. doi: 10.1016/j.bbalip.2014.06.008. Epub 2014 Jun 21.

PMID:
24960100
25.

Development of fluorescent double-strand probes labeled with 8-(p-CF3-cinnamyl)-adenosine for the detection of cyclin D1 breast cancer marker.

Zilbershtein-Shklanovsky L, Kafri P, Shav-Tal Y, Yavin E, Fischer B.

Eur J Med Chem. 2014 May 22;79:77-88. doi: 10.1016/j.ejmech.2014.03.081. Epub 2014 Mar 30.

PMID:
24727242
26.

Detection of cyclin D1 mRNA by hybridization sensitive NIC-oligonucleotide probe.

Kovaliov M, Segal M, Kafri P, Yavin E, Shav-Tal Y, Fischer B.

Bioorg Med Chem. 2014 May 1;22(9):2613-21. doi: 10.1016/j.bmc.2014.03.033. Epub 2014 Mar 29.

PMID:
24726303
27.

Use of peptide nucleic acids to manipulate gene expression in the malaria parasite Plasmodium falciparum.

Kolevzon N, Nasereddin A, Naik S, Yavin E, Dzikowski R.

PLoS One. 2014 Jan 22;9(1):e86802. doi: 10.1371/journal.pone.0086802. eCollection 2014.

28.

Mutant KRAS is a druggable target for pancreatic cancer.

Zorde Khvalevsky E, Gabai R, Rachmut IH, Horwitz E, Brunschwig Z, Orbach A, Shemi A, Golan T, Domb AJ, Yavin E, Giladi H, Rivkin L, Simerzin A, Eliakim R, Khalaileh A, Hubert A, Lahav M, Kopelman Y, Goldin E, Dancour A, Hants Y, Arbel-Alon S, Abramovitch R, Shemi A, Galun E.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20723-8. doi: 10.1073/pnas.1314307110. Epub 2013 Dec 2.

29.

Design, synthesis and structure-activity relationship of novel Relacin analogs as inhibitors of Rel proteins.

Wexselblatt E, Kaspy I, Glaser G, Katzhendler J, Yavin E.

Eur J Med Chem. 2013;70:497-504. doi: 10.1016/j.ejmech.2013.10.036. Epub 2013 Oct 22.

PMID:
24189495
30.

Detection of mRNA of the cyclin D1 breast cancer marker by a novel duplex-DNA probe.

Segal M, Yavin E, Kafri P, Shav-Tal Y, Fischer B.

J Med Chem. 2013 Jun 27;56(12):4860-9. doi: 10.1021/jm301838y. Epub 2013 Jun 6.

PMID:
23688195
31.

PfSec13 is an unusual chromatin-associated nucleoporin of Plasmodium falciparum that is essential for parasite proliferation in human erythrocytes.

Dahan-Pasternak N, Nasereddin A, Kolevzon N, Pe'er M, Wong W, Shinder V, Turnbull L, Whitchurch CB, Elbaum M, Gilberger TW, Yavin E, Baum J, Dzikowski R.

J Cell Sci. 2013 Jul 15;126(Pt 14):3055-69. doi: 10.1242/jcs.122119. Epub 2013 May 17.

32.

Platinum(IV) prodrugs with haloacetato ligands in the axial positions can undergo hydrolysis under biologically relevant conditions.

Wexselblatt E, Yavin E, Gibson D.

Angew Chem Int Ed Engl. 2013 Jun 3;52(23):6059-62. doi: 10.1002/anie.201300640. Epub 2013 May 17.

PMID:
23686723
33.

Detection of a long non-coding RNA (CCAT1) in living cells and human adenocarcinoma of colon tissues using FIT-PNA molecular beacons.

Kam Y, Rubinstein A, Naik S, Djavsarov I, Halle D, Ariel I, Gure AO, Stojadinovic A, Pan H, Tsivin V, Nissan A, Yavin E.

Cancer Lett. 2014 Sep 28;352(1):90-6. doi: 10.1016/j.canlet.2013.02.014. Epub 2013 Feb 14.

PMID:
23416875
34.

Bio-imaging of colorectal cancer models using near infrared labeled epidermal growth factor.

Cohen G, Lecht S, Arien-Zakay H, Ettinger K, Amsalem O, Oron-Herman M, Yavin E, Prus D, Benita S, Nissan A, Lazarovici P.

PLoS One. 2012;7(11):e48803. doi: 10.1371/journal.pone.0048803. Epub 2012 Nov 8.

35.

Relacin, a novel antibacterial agent targeting the Stringent Response.

Wexselblatt E, Oppenheimer-Shaanan Y, Kaspy I, London N, Schueler-Furman O, Yavin E, Glaser G, Katzhendler J, Ben-Yehuda S.

PLoS Pathog. 2012 Sep;8(9):e1002925. doi: 10.1371/journal.ppat.1002925. Epub 2012 Sep 20.

36.

The relative roles of charge and a recognition peptide in luminal targeting of colorectal cancer by fluorescent polyacrylamide.

Bloch M, Kam Y, Yavin E, Moradov D, Nissan A, Ariel I, Rubinstein A.

Eur J Pharm Sci. 2012 Dec 18;47(5):904-13. doi: 10.1016/j.ejps.2012.09.003. Epub 2012 Sep 25.

PMID:
23022517
37.

NGF blocks polyunsaturated fatty acids biosynthesis in n-3 fatty acid-supplemented PC12 cells.

Msika O, Brand A, Crawford MA, Yavin E.

Biochim Biophys Acta. 2012 Jul;1821(7):1022-30. doi: 10.1016/j.bbalip.2012.04.007. Epub 2012 Apr 28.

PMID:
22564256
38.

Detection of endogenous K-ras mRNA in living cells at a single base resolution by a PNA molecular beacon.

Kam Y, Rubinstein A, Nissan A, Halle D, Yavin E.

Mol Pharm. 2012 Mar 5;9(3):685-93. doi: 10.1021/mp200505k. Epub 2012 Feb 8.

PMID:
22289057
39.

Detecting a secreted gastric cancer biomarker molecule by targeted nanoparticles for real-time diagnostics.

Khazanov E, Yavin E, Pascal A, Nissan A, Kohl Y, Reimann-Zawadzki M, Rubinstein A.

Pharm Res. 2012 Apr;29(4):983-93. doi: 10.1007/s11095-011-0638-8. Epub 2011 Dec 10.

PMID:
22160813
40.

Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue.

Shekh-Ahmad T, Bialer M, Yavin E.

Epilepsy Res. 2012 Feb;98(2-3):238-46. doi: 10.1016/j.eplepsyres.2011.10.005. Epub 2011 Nov 6.

PMID:
22057163
41.

Multiple triphenylphosphonium cations as a platform for the delivery of a pro-apoptotic peptide.

Kolevzon N, Kuflik U, Shmuel M, Benhamron S, Ringel I, Yavin E.

Pharm Res. 2011 Nov;28(11):2780-9. doi: 10.1007/s11095-011-0494-6. Epub 2011 Jun 2.

PMID:
21633875
42.

c-di-AMP reports DNA integrity during sporulation in Bacillus subtilis.

Oppenheimer-Shaanan Y, Wexselblatt E, Katzhendler J, Yavin E, Ben-Yehuda S.

EMBO Rep. 2011 Jun;12(6):594-601. doi: 10.1038/embor.2011.77. Epub 2011 May 13.

43.

Site-specific DNA photocleavage and photomodulation by oligonucleotide conjugates.

Kolevzon N, Yavin E.

Oligonucleotides. 2010 Dec;20(6):263-75. doi: 10.1089/oli.2010.0247. Epub 2010 Sep 23.

PMID:
20863234
44.

A metal-free DNA nuclease based on a cyclic peptide scaffold.

Alkhader S, Ezra A, Kasparkova J, Brabec V, Yavin E.

Bioconjug Chem. 2010 Aug 18;21(8):1425-31. doi: 10.1021/bc900543b.

PMID:
20715847
45.

Specific detection of gastric alpha-antitrypsin by immobilized trypsin on polyHEMA films.

Khazanov E, Emmanuel N, Azab AK, Barenholz Y, Yavin E, Rubinstein A.

Mol Pharm. 2010 Aug 2;7(4):944-52. doi: 10.1021/mp100076x.

PMID:
20583815
46.

Retailoring docosahexaenoic acid-containing phospholipid species during impaired neurogenesis following omega-3 alpha-linolenic acid deprivation.

Brand A, Crawford MA, Yavin E.

J Neurochem. 2010 Sep 1;114(5):1393-404. doi: 10.1111/j.1471-4159.2010.06866.x. Epub 2010 Jun 16.

47.

DNA photocleavage by DNA and DNA-LNA amino acid-dye conjugates.

Biton A, Ezra A, Kasparkova J, Brabec V, Yavin E.

Bioconjug Chem. 2010 Apr 21;21(4):616-21. doi: 10.1021/bc900372h.

PMID:
20345124
48.

Oligonucleotides are potent antioxidants acting primarily through metal ion chelation.

Zobel E, Yavin E, Gottlieb HE, Segal M, Fischer B.

J Biol Inorg Chem. 2010 May;15(4):601-20. doi: 10.1007/s00775-010-0628-z. Epub 2010 Feb 13.

PMID:
20155378
49.

Multiple triphenylphosphonium cations shuttle a hydrophilic peptide into mitochondria.

Abu-Gosh SE, Kolvazon N, Tirosh B, Ringel I, Yavin E.

Mol Pharm. 2009 Jul-Aug;6(4):1138-44. doi: 10.1021/mp900032r.

PMID:
19534554
50.

Delayed cell migration in the developing rat brain following maternal omega 3 alpha linolenic acid dietary deficiency.

Yavin E, Himovichi E, Eilam R.

Neuroscience. 2009 Sep 15;162(4):1011-22. doi: 10.1016/j.neuroscience.2009.05.012. Epub 2009 May 14.

PMID:
19447164

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