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Items: 1 to 50 of 277

1.

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.

Yu K, Chen B, Aran D, Charalel J, Yau C, Wolf DM, van 't Veer LJ, Butte AJ, Goldstein T, Sirota M.

Nat Commun. 2019 Aug 8;10(1):3574. doi: 10.1038/s41467-019-11415-2.

2.

Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients With Luminal A or Luminal B Breast Cancer.

Yu NY, Iftimi A, Yau C, Tobin NP, van 't Veer L, Hoadley KA, Benz CC, Nordenskjöld B, Fornander T, Stål O, Czene K, Esserman LJ, Lindström LS.

JAMA Oncol. 2019 Aug 8. doi: 10.1001/jamaoncol.2019.1856. [Epub ahead of print]

PMID:
31393518
3.

The WISDOM Personalized Breast Cancer Screening Trial: Simulation Study to Assess Potential Bias and Analytic Approaches.

Eklund M, Broglio K, Yau C, Connor JT, Stover Fiscalini A, Esserman LJ.

JNCI Cancer Spectr. 2019 Jan 8;2(4):pky067. doi: 10.1093/jncics/pky067. eCollection 2018 Oct.

4.

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma.

Mourikis TP, Benedetti L, Foxall E, Temelkovski D, Nulsen J, Perner J, Cereda M, Lagergren J, Howell M, Yau C, Fitzgerald RC, Scaffidi P; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, Ciccarelli FD.

Nat Commun. 2019 Jul 15;10(1):3101. doi: 10.1038/s41467-019-10898-3.

5.

Targeting Mitochondrial Proline Dehydrogenase with a Suicide Inhibitor to Exploit Synthetic Lethal Interactions with p53 Upregulation and Glutaminase Inhibition.

Scott GK, Yau C, Becker BC, Khateeb S, Mahoney S, Jensen MB, Hann B, Cowen BJ, Pegan SD, Benz CC.

Mol Cancer Ther. 2019 Aug;18(8):1374-1385. doi: 10.1158/1535-7163.MCT-18-1323. Epub 2019 Jun 12.

PMID:
31189611
6.

Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities.

Coppé JP, Mori M, Pan B, Yau C, Wolf DM, Ruiz-Saenz A, Brunen D, Prahallad A, Cornelissen-Steijger P, Kemper K, Posch C, Wang C, Dreyer CA, Krijgsman O, Lee PRE, Chen Z, Peeper DS, Moasser MM, Bernards R, van 't Veer LJ.

Nat Cell Biol. 2019 Jun;21(6):778-790. doi: 10.1038/s41556-019-0328-z. Epub 2019 Jun 3.

PMID:
31160710
7.

Synchronous Detection of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow Predicts Adverse Outcome in Early Breast Cancer.

Magbanua MJM, Yau C, Wolf DM, Lee JS, Chattopadhyay A, Scott JH, Bowlby-Yoder E, Hwang ES, Alvarado M, Ewing CA, Delson AL, Van't Veer LJ, Esserman L, Park JW.

Clin Cancer Res. 2019 Sep 1;25(17):5388-5397. doi: 10.1158/1078-0432.CCR-18-3888. Epub 2019 May 29.

PMID:
31142502
8.

Assessing Airflow Limitation among Smokers in a Primary Care Setting.

Yau CK, Rahim FF, Sheng CJ, Ling CX, Weng LK, Chia TC, Chye TK, Ting OS, Jin TH, Ali IAH.

Malays J Med Sci. 2018 May;25(3):78-87. doi: 10.21315/mjms2018.25.3.8. Epub 2018 Jun 28.

9.

Differences in gait and trunk movement between patients after ankle fracture and healthy subjects.

Hsu CY, Tsai YS, Yau CS, Shie HH, Wu CM.

Biomed Eng Online. 2019 Mar 19;18(1):26. doi: 10.1186/s12938-019-0644-3.

10.

A response to "Personalised medicine and population health: breast and ovarian cancer".

Antoniou A, Anton-Culver H, Borowsky A, Broeders M, Brooks J, Chiarelli A, Chiquette J, Cuzick J, Delaloge S, Devilee P, Dorval M, Easton D, Eisen A, Eklund M, Eloy L, Esserman L, Garcia-Closas M, Goldgar D, Hall P, Knoppers BM, Kraft P, La Croix A, Madalensky L, Mavaddat N, Mittman N, Nabi H, Olopade O, Pashayan N, Schmidt M, Shieh Y, Simard J, Stover-Fiscallini A, Tice JA, Van't Veer L, Wenger N, Wolfson M, Yau C, Ziv E.

Hum Genet. 2019 Mar;138(3):287-289. doi: 10.1007/s00439-019-01984-z. Epub 2019 Feb 27. No abstract available.

11.

Bayesian statistical learning for big data biology.

Yau C, Campbell K.

Biophys Rev. 2019 Feb;11(1):95-102. doi: 10.1007/s12551-019-00499-1. Epub 2019 Feb 7. Review.

12.

Immunophenotypes of pancreatic ductal adenocarcinoma: Meta-analysis of transcriptional subtypes.

de Santiago I, Yau C, Heij L, Middleton MR, Markowetz F, Grabsch HI, Dustin ML, Sivakumar S.

Int J Cancer. 2019 Aug 15;145(4):1125-1137. doi: 10.1002/ijc.32186. Epub 2019 Mar 18.

13.

Association of HLA-dependent islet autoimmunity with systemic antibody responses to intestinal commensal bacteria in children.

Paun A, Yau C, Meshkibaf S, Daigneault MC, Marandi L, Mortin-Toth S, Bar-Or A, Allen-Vercoe E, Poussier P, Danska JS.

Sci Immunol. 2019 Feb 1;4(32). pii: eaau8125. doi: 10.1126/sciimmunol.aau8125.

PMID:
30709843
14.

Obstetric brachial plexus injuries (OBPIs): health-related quality of life in affected adults and parents.

Yau CWH, Pizzo E, Prajapati C, Draycott T, Lenguerrand E.

Health Qual Life Outcomes. 2018 Nov 15;16(1):212. doi: 10.1186/s12955-018-1039-z.

15.

The therapeutic effect of scalp acupuncture on natal autism and regressive autism.

Yau CH, Ip CL, Chau YY.

Chin Med. 2018 Jun 15;13:30. doi: 10.1186/s13020-018-0189-6. eCollection 2018.

16.

A descriptive marker gene approach to single-cell pseudotime inference.

Campbell KR, Yau C.

Bioinformatics. 2019 Jan 1;35(1):28-35. doi: 10.1093/bioinformatics/bty498.

17.

Uncovering pseudotemporal trajectories with covariates from single cell and bulk expression data.

Campbell KR, Yau C.

Nat Commun. 2018 Jun 22;9(1):2442. doi: 10.1038/s41467-018-04696-6.

18.

Corneal Inlays for Presbyopia Explanted Due to Corneal Haze.

Ong HS, Chan AS, Yau CW, Mehta JS.

J Refract Surg. 2018 May 1;34(5):357-360. doi: 10.3928/1081597X-20180308-01.

PMID:
29738595
19.

Nurse-initiated radiographic-test protocol for ankle injuries: A randomized controlled trial.

Ho JK, Chau JP, Chan JT, Yau CH.

Int Emerg Nurs. 2018 Nov;41:1-6. doi: 10.1016/j.ienj.2018.04.001. Epub 2018 Apr 25.

PMID:
29703591
20.

Associations between birth at, or after, 41 weeks gestation and perinatal encephalopathy: a cohort study.

Odd DE, Yau C, Winter C, Draycott T, Rasmussen F.

BMJ Paediatr Open. 2018 Jan 24;2(1):e000010. doi: 10.1136/bmjpo-2017-000010. eCollection 2018.

21.

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

Hoadley KA, Yau C, Hinoue T, Wolf DM, Lazar AJ, Drill E, Shen R, Taylor AM, Cherniack AD, Thorsson V, Akbani R, Bowlby R, Wong CK, Wiznerowicz M, Sanchez-Vega F, Robertson AG, Schneider BG, Lawrence MS, Noushmehr H, Malta TM; Cancer Genome Atlas Network, Stuart JM, Benz CC, Laird PW.

Cell. 2018 Apr 5;173(2):291-304.e6. doi: 10.1016/j.cell.2018.03.022.

22.

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.

Berger AC, Korkut A, Kanchi RS, Hegde AM, Lenoir W, Liu W, Liu Y, Fan H, Shen H, Ravikumar V, Rao A, Schultz A, Li X, Sumazin P, Williams C, Mestdagh P, Gunaratne PH, Yau C, Bowlby R, Robertson AG, Tiezzi DG, Wang C, Cherniack AD, Godwin AK, Kuderer NM, Rader JS, Zuna RE, Sood AK, Lazar AJ, Ojesina AI, Adebamowo C, Adebamowo SN, Baggerly KA, Chen TW, Chiu HS, Lefever S, Liu L, MacKenzie K, Orsulic S, Roszik J, Shelley CS, Song Q, Vellano CP, Wentzensen N; Cancer Genome Atlas Research Network, Weinstein JN, Mills GB, Levine DA, Akbani R.

Cancer Cell. 2018 Apr 9;33(4):690-705.e9. doi: 10.1016/j.ccell.2018.03.014. Epub 2018 Apr 2.

23.

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.

Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf D, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I; Cancer Genome Atlas Research Network, Monnat RJ Jr, Xiao Y, Wang C.

Cell Rep. 2018 Apr 3;23(1):239-254.e6. doi: 10.1016/j.celrep.2018.03.076.

24.

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.

Campbell JD, Yau C, Bowlby R, Liu Y, Brennan K, Fan H, Taylor AM, Wang C, Walter V, Akbani R, Byers LA, Creighton CJ, Coarfa C, Shih J, Cherniack AD, Gevaert O, Prunello M, Shen H, Anur P, Chen J, Cheng H, Hayes DN, Bullman S, Pedamallu CS, Ojesina AI, Sadeghi S, Mungall KL, Robertson AG, Benz C, Schultz A, Kanchi RS, Gay CM, Hegde A, Diao L, Wang J, Ma W, Sumazin P, Chiu HS, Chen TW, Gunaratne P, Donehower L, Rader JS, Zuna R, Al-Ahmadie H, Lazar AJ, Flores ER, Tsai KY, Zhou JH, Rustgi AK, Drill E, Shen R, Wong CK; Cancer Genome Atlas Research Network, Stuart JM, Laird PW, Hoadley KA, Weinstein JN, Peto M, Pickering CR, Chen Z, Van Waes C.

Cell Rep. 2018 Apr 3;23(1):194-212.e6. doi: 10.1016/j.celrep.2018.03.063.

25.

The Hamming Ball Sampler.

Titsias MK, Yau C.

J Am Stat Assoc. 2017 Sep 3;112(520):1598-1611. doi: 10.1080/01621459.2016.1222288. eCollection 2017.

26.

Airway ciliary dysfunction and respiratory symptoms in patients with transposition of the great arteries.

Zahid M, Bais A, Tian X, Devine W, Lee DM, Yau C, Sonnenberg D, Beerman L, Khalifa O, Lo CW.

PLoS One. 2018 Feb 14;13(2):e0191605. doi: 10.1371/journal.pone.0191605. eCollection 2018.

27.

Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.

Zheng Y, Sethi R, Mangala LS, Taylor C, Goldsmith J, Wang M, Masuda K, Karaminejadranjbar M, Mannion D, Miranda F, Herrero-Gonzalez S, Hellner K, Chen F, Alsaadi A, Albukhari A, Fotso DC, Yau C, Jiang D, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, Knapp S, Gray NS, Campo L, Myers KA, Dhar S, Ferguson D, Bast RC Jr, Sood AK, von Delft F, Ahmed AA.

Nat Commun. 2018 Feb 2;9(1):476. doi: 10.1038/s41467-017-02811-7.

28.

Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer.

Lindström LS, Yau C, Czene K, Thompson CK, Hoadley KA, Van't Veer LJ, Balassanian R, Bishop JW, Carpenter PM, Chen YY, Datnow B, Hasteh F, Krings G, Lin F, Zhang Y, Nordenskjöld B, Stål O, Benz CC, Fornander T, Borowsky AD, Esserman LJ; STO Trialists Group.

J Natl Cancer Inst. 2018 Jul 1;110(7):726-733. doi: 10.1093/jnci/djx270.

29.

Ascites Due to Constrictive Pericardial Disease Not Appreciated on Echocardiogram: A Report of Three Cases.

Han SB, Yau C, Chin EE.

Dig Dis Sci. 2018 Mar;63(3):797-802. doi: 10.1007/s10620-018-4920-z. Epub 2018 Jan 18. No abstract available.

PMID:
29349692
30.

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma.

Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Walter V, Danilova L, Lichtenberg TM, Kucherlapati M, Kimes PK, Tang M, Penson A, Babur O, Akbani R, Bristow CA, Hoadley KA, Iype L, Chang MT; TCGA Research Network, Cherniack AD, Benz C, Mills GB, Verhaak RGW, Griewank KG, Felau I, Zenklusen JC, Gershenwald JE, Schoenfield L, Lazar AJ, Abdel-Rahman MH, Roman-Roman S, Stern MH, Cebulla CM, Williams MD, Jager MJ, Coupland SE, Esmaeli B, Kandoth C, Woodman SE.

Cancer Cell. 2018 Jan 8;33(1):151. doi: 10.1016/j.ccell.2017.12.013. No abstract available.

31.

Discovery of internalizing antibodies to basal breast cancer cells.

Zhou Y, Zou H, Yau C, Zhao L, Hall SC, Drummond DC, Farr-Jones S, Park JW, Benz CC, Marks JD.

Protein Eng Des Sel. 2018 Jan 1;31(1):17-28. doi: 10.1093/protein/gzx063.

32.

Features of MRI stromal enhancement with neoadjuvant chemotherapy: a subgroup analysis of the ACRIN 6657/I-SPY TRIAL.

Olshen A, Wolf D, Jones EF, Newitt D, van ‘t Veer LJ, Yau C, Esserman L, Wulfkuhle JD, Gallagher RI, Singer L, Petricoin EF 3rd, Hylton N, Park CC.

J Med Imaging (Bellingham). 2018 Jan;5(1):011014. doi: 10.1117/1.JMI.5.1.011014. Epub 2017 Dec 23.

33.

Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans.

Rigoni A, Poulsom R, Jeffery R, Mehta S, Lewis A, Yau C, Giannoulatou E, Feakins R, Lindsay JO, Colombo MP, Silver A.

Inflamm Bowel Dis. 2017 Dec 19;24(1):136-148. doi: 10.1093/ibd/izx024.

PMID:
29272487
34.

Japanese Encephalitis Virus Transmitted Via Blood Transfusion, Hong Kong, China.

Cheng VCC, Sridhar S, Wong SC, Wong SCY, Chan JFW, Yip CCY, Chau CH, Au TWK, Hwang YY, Yau CSW, Lo JYC, Lee CK, Yuen KY.

Emerg Infect Dis. 2018 Jan;24(1). doi: 10.3201/eid2401.171297. Epub 2018 Jan 17.

35.

DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.

Wolf DM, Yau C, Sanil A, Glas A, Petricoin E, Wulfkuhle J, Severson TM, Linn S, Brown-Swigart L, Hirst G, Buxton M, DeMichele A, Hylton N, Symmans F, Yee D, Paoloni M, Esserman L, Berry D, Rugo H, Olopade O, van 't Veer L.

NPJ Breast Cancer. 2017 Aug 25;3:31. doi: 10.1038/s41523-017-0025-7. eCollection 2017.

36.

Evaluating a bedside tool for neuroanatomical localization with extended-matching questions.

Tan K, Chin HX, Yau CWL, Lim ECH, Samarasekera D, Ponnamperuma G, Tan NCK.

Anat Sci Educ. 2018 May 6;11(3):262-269. doi: 10.1002/ase.1741. Epub 2017 Sep 22.

PMID:
28941011
37.

MicroRNA profiling study reveals miR-150 in association with metastasis in nasopharyngeal carcinoma.

Yue PY, Ha WY, Lau CC, Cheung FM, Lee AW, Ng WT, Ngan RK, Yau CC, Kwong DL, Lung HL, Mak NK, Lung ML, Wong RN.

Sci Rep. 2017 Sep 20;7(1):12012. doi: 10.1038/s41598-017-10695-2.

38.

The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting.

Severson TM, Wolf DM, Yau C, Peeters J, Wehkam D, Schouten PC, Chin SF, Majewski IJ, Michaut M, Bosma A, Pereira B, Bismeijer T, Wessels L, Caldas C, Bernards R, Simon IM, Glas AM, Linn S, van 't Veer L.

Breast Cancer Res. 2017 Aug 25;19(1):99. doi: 10.1186/s13058-017-0861-2.

39.

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma.

Robertson AG, Shih J, Yau C, Gibb EA, Oba J, Mungall KL, Hess JM, Uzunangelov V, Walter V, Danilova L, Lichtenberg TM, Kucherlapati M, Kimes PK, Tang M, Penson A, Babur O, Akbani R, Bristow CA, Hoadley KA, Iype L, Chang MT; TCGA Research Network, Cherniack AD, Benz C, Mills GB, Verhaak RGW, Griewank KG, Felau I, Zenklusen JC, Gershenwald JE, Schoenfield L, Lazar AJ, Abdel-Rahman MH, Roman-Roman S, Stern MH, Cebulla CM, Williams MD, Jager MJ, Coupland SE, Esmaeli B, Kandoth C, Woodman SE.

Cancer Cell. 2017 Aug 14;32(2):204-220.e15. doi: 10.1016/j.ccell.2017.07.003. Erratum in: Cancer Cell. 2018 Jan 8;33(1):151.

40.

Determination of the mutant-prevention concentration of imipenem for the two imipenem-susceptible Bacteroides fragilis strains, Q1F2 (cfiA-positive) and ATCC 25282 (cfiA-negative).

Ho PL, Yau CY, Wang Y, Chow KH.

Int J Antimicrob Agents. 2018 Feb;51(2):270-271. doi: 10.1016/j.ijantimicag.2017.08.004. Epub 2017 Aug 4. No abstract available.

PMID:
28782706
41.

Tamoxifen therapy benefit for patients with 70-gene signature high and low risk.

van 't Veer LJ, Yau C, Yu NY, Benz CC, Nordenskjöld B, Fornander T, Stål O, Esserman LJ, Lindström LS.

Breast Cancer Res Treat. 2017 Nov;166(2):593-601. doi: 10.1007/s10549-017-4428-9. Epub 2017 Aug 4.

42.

Differentially localized rice ethylene receptors OsERS1 and OsETR2 and their potential role during submergence.

Yu M, Yau CP, Yip WK.

Plant Signal Behav. 2017 Aug 3;12(8):e1356532. doi: 10.1080/15592324.2017.1356532. Epub 2017 Jul 31.

43.

Response to 'Telling the whole story about simulation-based education'.

Yau CWH, Pizzo E, Morris S, Odd DE, Winter C, Draycott TJ.

Acta Obstet Gynecol Scand. 2017 Oct;96(10):1274. doi: 10.1111/aogs.13196. Epub 2017 Aug 18. No abstract available.

PMID:
28742935
44.

ST elevation myocardial infarction after coronary artery spasm with no clear trigger.

Patel P, Yau C, Kurian J.

Br J Hosp Med (Lond). 2017 Jul 2;78(7):412-413. doi: 10.12968/hmed.2017.78.7.412. No abstract available.

PMID:
28692363
45.

Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades.

Esserman LJ, Yau C, Thompson CK, van 't Veer LJ, Borowsky AD, Hoadley KA, Tobin NP, Nordenskjöld B, Fornander T, Stål O, Benz CC, Lindström LS.

JAMA Oncol. 2017 Nov 1;3(11):1503-1510. doi: 10.1001/jamaoncol.2017.1261. Erratum in: JAMA Oncol. 2017 Nov 1;3(11):1589.

46.

A pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decay.

Hu Z, Yau C, Ahmed AA.

Nat Commun. 2017 Jun 26;8:15943. doi: 10.1038/ncomms15943.

47.

Colorectal Cancer Cell Line Proteomes Are Representative of Primary Tumors and Predict Drug Sensitivity.

Wang J, Mouradov D, Wang X, Jorissen RN, Chambers MC, Zimmerman LJ, Vasaikar S, Love CG, Li S, Lowes K, Leuchowius KJ, Jousset H, Weinstock J, Yau C, Mariadason J, Shi Z, Ban Y, Chen X, Coffey RJC, Slebos RJC, Burgess AW, Liebler DC, Zhang B, Sieber OM.

Gastroenterology. 2017 Oct;153(4):1082-1095. doi: 10.1053/j.gastro.2017.06.008. Epub 2017 Jun 16.

48.
49.

Comparison of residual cancer burden, American Joint Committee on Cancer staging and pathologic complete response in breast cancer after neoadjuvant chemotherapy: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657).

Campbell JI, Yau C, Krass P, Moore D, Carey LA, Au A, Chhieng D, Giri D, Livasy C, Mies C, Rabban J, Sarode VR, Singh B, Esserman L, Chen YY.

Breast Cancer Res Treat. 2017 Aug;165(1):181-191. doi: 10.1007/s10549-017-4303-8. Epub 2017 Jun 2.

50.

Probabilistic modeling of bifurcations in single-cell gene expression data using a Bayesian mixture of factor analyzers.

Campbell KR, Yau C.

Wellcome Open Res. 2017 Mar 15;2:19. doi: 10.12688/wellcomeopenres.11087.1.

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