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Items: 1 to 50 of 67

1.

Urinary Leukotriene E4 and 2,3-Dinor Thromboxane B2 Are Biomarkers of Potential Harm in Short-Term Tobacco Switching Studies.

Makena P, Liu G, Chen P, Yates CR, Prasad GL.

Cancer Epidemiol Biomarkers Prev. 2019 Dec;28(12):2095-2105. doi: 10.1158/1055-9965.EPI-19-0342. Epub 2019 Sep 26.

PMID:
31558507
2.

"…Not Intended to Diagnose, Treat, Cure or Prevent Any Disease." 25 Years of Botanical Dietary Supplement Research and the Lessons Learned.

Gurley BJ, Yates CR, Markowitz JS.

Clin Pharmacol Ther. 2018 Sep;104(3):470-483. doi: 10.1002/cpt.1131. Epub 2018 Jul 13. Review.

PMID:
29882958
3.

Genome-Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor.

Bime C, Pouladi N, Sammani S, Batai K, Casanova N, Zhou T, Kempf CL, Sun X, Camp SM, Wang T, Kittles RA, Lussier YA, Jones TK, Reilly JP, Meyer NJ, Christie JD, Karnes JH, Gonzalez-Garay M, Christiani DC, Yates CR, Wurfel MM, Meduri GU, Garcia JGN.

Am J Respir Crit Care Med. 2018 Jun 1;197(11):1421-1432. doi: 10.1164/rccm.201705-0961OC.

4.

Polycystin-1 interacts with TAZ to stimulate osteoblastogenesis and inhibit adipogenesis.

Xiao Z, Baudry J, Cao L, Huang J, Chen H, Yates CR, Li W, Dong B, Waters CM, Smith JC, Quarles LD.

J Clin Invest. 2018 Jan 2;128(1):157-174. doi: 10.1172/JCI93725. Epub 2017 Nov 27.

5.

Ensemble docking to difficult targets in early-stage drug discovery: Methodology and application to fibroblast growth factor 23.

Velazquez HA, Riccardi D, Xiao Z, Quarles LD, Yates CR, Baudry J, Smith JC.

Chem Biol Drug Des. 2018 Feb;91(2):491-504. doi: 10.1111/cbdd.13110. Epub 2017 Nov 3.

PMID:
28944571
6.

Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans.

He H, Ma D, Crone LB, Butawan M, Meibohm B, Bloomer RJ, Yates CR.

J Caffeine Res. 2017 Sep 1;7(3):95-102. doi: 10.1089/jcr.2017.0006.

7.

The quinic acid derivative KZ-41 prevents glucose-induced caspase-3 activation in retinal endothelial cells through an IGF-1 receptor dependent mechanism.

He H, Weir RL, Toutounchian JJ, Pagadala J, Steinle JJ, Baudry J, Miller DD, Yates CR.

PLoS One. 2017 Aug 10;12(8):e0180808. doi: 10.1371/journal.pone.0180808. eCollection 2017.

8.

Novel Small Molecule JP-153 Targets the Src-FAK-Paxillin Signaling Complex to Inhibit VEGF-Induced Retinal Angiogenesis.

Toutounchian JJ, Pagadala J, Miller DD, Baudry J, Park F, Chaum E, Morales-Tirado V, Yates CR.

Mol Pharmacol. 2017 Jan;91(1):1-13. Epub 2016 Nov 9. Erratum in: Mol Pharmacol. 2017 Dec;92 (6):627.

PMID:
27913654
9.

A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia.

Xiao Z, Riccardi D, Velazquez HA, Chin AL, Yates CR, Carrick JD, Smith JC, Baudry J, Quarles LD.

Sci Signal. 2016 Nov 22;9(455):ra113. Erratum in: Sci Signal. 2016 Dec 06;9(457):er3.

10.

Mitigation of the hematopoietic and gastrointestinal acute radiation syndrome by octadecenyl thiophosphate, a small molecule mimic of lysophosphatidic acid.

Deng W, Kimura Y, Gududuru V, Wu W, Balogh A, Szabo E, Thompson KE, Yates CR, Balazs L, Johnson LR, Miller DD, Strobos J, McCool WS, Tigyi GJ.

Radiat Res. 2015 Apr;183(4):465-75. doi: 10.1667/RR13830.1. Epub 2015 Mar 25.

11.

Exaggerated plasma interleukin 6, interleukin 10, and subsequent development of health care-associated infections in patients with sepsis.

Umberger R, Thompson CL, Cashion AK, Kuhl D, Wan J, Yates CR, Muthiah MP, Meduri GU.

Dimens Crit Care Nurs. 2015 Mar-Apr;34(2):100-11. doi: 10.1097/DCC.0000000000000098.

PMID:
25650495
12.

Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist.

Patil R, Szabó E, Fells JI, Balogh A, Lim KG, Fujiwara Y, Norman DD, Lee SC, Balazs L, Thomas F, Patil S, Emmons-Thompson K, Boler A, Strobos J, McCool SW, Yates CR, Stabenow J, Byrne GI, Miller DD, Tigyi GJ.

Chem Biol. 2015 Feb 19;22(2):206-16. doi: 10.1016/j.chembiol.2014.12.009. Epub 2015 Jan 22.

13.

EDL-360: A Potential Novel Antiglioma Agent.

Hosni-Ahmed A, Sims M, Jones TS, Patil R, Patil S, Abdelsamed H, Yates CR, Miller DD, Pfeffer LM.

J Cancer Sci Ther. 2014 Sep 25;6(9):370-377.

14.

Radiation combined injury models to study the effects of interventions and wound biomechanics.

Zawaski JA, Yates CR, Miller DD, Kaffes CC, Sabek OM, Afshar SF, Young DA, Yang Y, Gaber MW.

Radiat Res. 2014 Dec;182(6):640-52. doi: 10.1667/RR13751.1.

PMID:
25409125
15.

Modulation of radiation injury response in retinal endothelial cells by quinic acid derivative KZ-41 involves p38 MAPK.

Toutounchian JJ, Steinle JJ, Makena PS, Waters CM, Wilson MW, Haik BG, Miller DD, Yates CR.

PLoS One. 2014 Jun 23;9(6):e100210. doi: 10.1371/journal.pone.0100210. eCollection 2014.

16.

Quinic acid derivative KZ-41 exhibits radiomitigating activity in preclinical models of radiation injury.

Thompson KE, Zeng K, Wilson CM, Gaber MW, Miller DD, Yates CR.

Drug Dev Res. 2014 Feb;75(1):29-36. doi: 10.1002/ddr.21164. Epub 2013 Dec 26.

PMID:
24648047
17.

A sensitive and fast LC-MS/MS method for determination of β-receptor agonist JP-49b: application to a pharmacokinetic study in rats.

He H, Williams-Guy K, Pagadala J, Presley CS, Miller DD, Steinle JJ, Yates CR.

J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Mar 15;953-954:86-91. doi: 10.1016/j.jchromb.2014.01.031. Epub 2014 Feb 8.

18.

In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.

Slominski AT, Kim TK, Shehabi HZ, Tang EK, Benson HA, Semak I, Lin Z, Yates CR, Wang J, Li W, Tuckey RC.

Mol Cell Endocrinol. 2014 Mar 5;383(1-2):181-92. doi: 10.1016/j.mce.2013.12.012. Epub 2013 Dec 29.

19.

Synthesis and characterization of an anti-apoptotic immunosuppressive compound for improving the outcome of islet transplantation.

Wu H, Pagadala J, Yates CR, Miller D, Mahato RI.

Bioconjug Chem. 2013 Dec 18;24(12):2036-44. doi: 10.1021/bc400369t. Epub 2013 Nov 27.

20.

Physiological and pharmacokinetic effects of oral 1,3-dimethylamylamine administration in men.

Schilling BK, Hammond KG, Bloomer RJ, Presley CS, Yates CR.

BMC Pharmacol Toxicol. 2013 Oct 4;14:52. doi: 10.1186/2050-6511-14-52.

21.

Novel quinic acid derivative KZ-41 prevents retinal endothelial cell apoptosis without inhibiting retinoblastoma cell death through p38 signaling.

Zhang Q, Jiang Y, Toutounchian J, Wilson MW, Morales-Tirado V, Miller DD, Yates CR, Steinle JJ.

Invest Ophthalmol Vis Sci. 2013 Sep 3;54(9):5937-43. doi: 10.1167/iovs.13-12326.

22.

Insulin-like growth factor binding protein-3 inhibits monocyte adhesion to retinal endothelial cells in high glucose conditions.

Zhang Q, Jiang Y, Toutounchian JJ, Soderland C, Yates CR, Steinle JJ.

Mol Vis. 2013 Apr 5;19:796-803. Print 2013.

23.

LC-MS/MS identification of the one-carbon cycle metabolites in human plasma.

Gardner LA, Desiderio DM, Groover CJ, Hartzes A, Yates CR, Zucker-Levin AR, Bloom L, Levin MC.

Electrophoresis. 2013 Jun;34(11):1710-6. doi: 10.1002/elps.201200536. Epub 2013 Apr 23.

PMID:
23417555
24.

Mitigation of radiation injury by selective stimulation of the LPA(2) receptor.

Kiss GN, Lee SC, Fells JI, Liu J, Valentine WJ, Fujiwara Y, Thompson KE, Yates CR, Sümegi B, Tigyi G.

Biochim Biophys Acta. 2013 Jan;1831(1):117-25. doi: 10.1016/j.bbalip.2012.08.020.

25.

Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes.

Slominski AT, Kim TK, Chen J, Nguyen MN, Li W, Yates CR, Sweatman T, Janjetovic Z, Tuckey RC.

Int J Biochem Cell Biol. 2012 Nov;44(11):2003-18. doi: 10.1016/j.biocel.2012.07.027. Epub 2012 Aug 2.

26.

In vivo evidence for a novel pathway of vitamin D₃ metabolism initiated by P450scc and modified by CYP27B1.

Slominski AT, Kim TK, Shehabi HZ, Semak I, Tang EK, Nguyen MN, Benson HA, Korik E, Janjetovic Z, Chen J, Yates CR, Postlethwaite A, Li W, Tuckey RC.

FASEB J. 2012 Sep;26(9):3901-15. doi: 10.1096/fj.12-208975. Epub 2012 Jun 8.

27.

Compound 49b prevents diabetes-induced apoptosis through increased IGFBP-3 levels.

Zhang Q, Guy K, Pagadala J, Jiang Y, Walker RJ, Liu L, Soderland C, Kern TS, Ferry R Jr, He H, Yates CR, Miller DD, Steinle JJ.

Invest Ophthalmol Vis Sci. 2012 May 17;53(6):3004-13. doi: 10.1167/iovs.11-8779.

28.

Intra-ophthalmic artery chemotherapy triggers vascular toxicity through endothelial cell inflammation and leukostasis.

Steinle JJ, Zhang Q, Thompson KE, Toutounchian J, Yates CR, Soderland C, Wang F, Stewart CF, Haik BG, Williams JS, Jackson JS, Mandrell TD, Johnson D, Wilson MW.

Invest Ophthalmol Vis Sci. 2012 Apr 30;53(4):2439-45. doi: 10.1167/iovs.12-9466.

29.

EDL-291, a novel isoquinoline, presents antiglioblastoma effects in vitro and in vivo.

Wang XD, Freeman NE, Patil R, Patil SA, Mitra S, Orr WE, Abner CW, Yates CR, Miller DD, Geisert EE.

Anticancer Drugs. 2012 Jun;23(5):494-504. doi: 10.1097/CAD.0b013e328351ee4f.

PMID:
22391460
30.

Preclinical pharmacokinetics of the radiomitigator KZ-41 in rats.

Zeng K, Thompson KE, Presley CS, Miller DD, Yates CR.

Xenobiotica. 2011 Nov;41(11):1006-12. doi: 10.3109/00498254.2011.603387. Epub 2011 Aug 25.

PMID:
21864202
31.

Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.

Gupte R, Patil R, Liu J, Wang Y, Lee SC, Fujiwara Y, Fells J, Bolen AL, Emmons-Thompson K, Yates CR, Siddam A, Panupinthu N, Pham TC, Baker DL, Parrill AL, Mills GB, Tigyi G, Miller DD.

ChemMedChem. 2011 May 2;6(5):922-35. doi: 10.1002/cmdc.201000425. Epub 2011 Apr 4.

32.

Pharmacokinetics of a combination of Δ9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock.

Vaddady PK, Mehrotra N, Zhang X, Yates CR, Moore BM, Meibohm B.

Biopharm Drug Dispos. 2011 Mar;32(2):89-98. doi: 10.1002/bdd.740. Epub 2010 Dec 23.

PMID:
21341278
33.

Development of an LC-MS/MS assay to determine plasma pharmacokinetics of the radioprotectant octadecenyl thiophosphate (OTP) in monkeys.

Kosanam H, Ma F, He H, Ramagiri S, Gududuru V, Tigyi GJ, Van Rompay K, Miller DD, Yates CR.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Sep 15;878(26):2379-83. doi: 10.1016/j.jchromb.2010.07.004. Epub 2010 Jul 18.

34.

Treating retinoblastoma in tissue culture and in a rat model with a novel isoquinoline derivative.

Nassr M, Wang X, Mitra S, Freeman-Anderson NE, Patil R, Yates CR, Miller DD, Geisert EE.

Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3813-9. doi: 10.1167/iovs.09-5042.

PMID:
20570997
35.

Synthesis and biological evaluation of quinic acid derivatives as anti-inflammatory agents.

Zeng K, Thompson KE, Yates CR, Miller DD.

Bioorg Med Chem Lett. 2009 Sep 15;19(18):5458-60. doi: 10.1016/j.bmcl.2009.07.096. Epub 2009 Jul 23.

PMID:
19674895
36.

Inter-individual variability of plasma PAF-acetylhydrolase activity in ARDS patients and PAFAH genotype.

Li S, Stuart L, Zhang Y, Meduri GU, Umberger R, Yates CR.

J Clin Pharm Ther. 2009 Aug;34(4):447-55. doi: 10.1111/j.1365-2710.2008.01014.x.

PMID:
19583678
37.

Transrepression and transactivation potencies of inhaled glucocorticoids.

Dirks NL, Li S, Huth B, Hochhaus G, Yates CR, Meibohm B.

Pharmazie. 2008 Dec;63(12):893-8.

PMID:
19177906
38.

Fast and sensitive liquid chromatography/electrospray mass spectrometry method to study ocular penetration of EDL-155, a novel antitumor agent for retinoblastoma in rats.

Ramagiri S, Ma F, Kosanam H, Wang X, Patil R, Miller DD, Geisert E, Yates CR.

J Mass Spectrom. 2009 May;44(5):786-93. doi: 10.1002/jms.1556.

PMID:
19160451
39.

Quantitative chiral analysis of phthaloylglutamic acid and related analogs by a single ratio kinetic method using electrospray ionization and matrix-assisted laser desorption techniques.

Ramagiri S, Gupte R, Rakov I, Yates CR, Miller DD.

Rapid Commun Mass Spectrom. 2008;22(5):639-46. doi: 10.1002/rcm.3405.

PMID:
18247407
40.

Plasma and cerebrospinal fluid pharmacokinetics of the novel tetrahydroisoquinoline EDL-155 in rats.

Song P, Ma F, Wang F, Wang X, Patil R, Ramagiri S, Orr WE, Miller DD, Geisert E, Yates CR.

Cancer Chemother Pharmacol. 2008 May;61(6):1037-44. Epub 2007 Sep 1.

PMID:
17768626
41.

Rapid screening of doping agents in human urine by vacuum MALDI-linear ion trap mass spectrometry.

Kosanam H, Prakash PK, Yates CR, Miller DD, Ramagiri S.

Anal Chem. 2007 Aug 1;79(15):6020-6. Epub 2007 Jun 30. Erratum in: Anal Chem. 2007 Nov 1;79(21):8420.

PMID:
17602668
42.

Macrophage migration inhibitory factor in acute lung injury: expression, biomarker, and associations.

Gao L, Flores C, Fan-Ma S, Miller EJ, Moitra J, Moreno L, Wadgaonkar R, Simon B, Brower R, Sevransky J, Tuder RM, Maloney JP, Moss M, Shanholtz C, Yates CR, Meduri GU, Ye SQ, Barnes KC, Garcia JG.

Transl Res. 2007 Jul;150(1):18-29. Epub 2007 May 25.

43.

Hexafunctionalized borromeates using olefin cross metathesis.

Yates CR, Benítez D, Khan SI, Stoddart JF.

Org Lett. 2007 Jun 21;9(13):2433-6. Epub 2007 May 22.

PMID:
17516651
44.

Status of PharmD/PhD programs in colleges of pharmacy: the University of Tennessee dual PharmD/PhD program.

Gourley DR, Rowell C, Wingate L, Yates CR, Gourley GK, Miller DD, Vleet V.

Am J Pharm Educ. 2006 Apr 15;70(2):44.

45.

Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans.

Gurley BJ, Swain A, Barone GW, Williams DK, Breen P, Yates CR, Stuart LB, Hubbard MA, Tong Y, Cheboyina S.

Drug Metab Dispos. 2007 Feb;35(2):240-5. Epub 2006 Nov 1.

46.

A modern view of excipient effects on bioequivalence: case study of sorbitol.

Chen ML, Straughn AB, Sadrieh N, Meyer M, Faustino PJ, Ciavarella AB, Meibohm B, Yates CR, Hussain AS.

Pharm Res. 2007 Jan;24(1):73-80. Epub 2006 Oct 18.

PMID:
17048115
47.

LC/MS/MS in drug development: targeting the brain.

Song P, Meibohm B, Yates CR.

Biotechniques. 2005 Jun;Suppl:19-23. Review. No abstract available.

48.

G2677T and C3435T genotype and haplotype are associated with hepatic ABCB1 (MDR1) expression.

Song P, Lamba JK, Zhang L, Schuetz E, Shukla N, Meibohm B, Yates CR.

J Clin Pharmacol. 2006 Mar;46(3):373-9. No abstract available.

PMID:
16490813
49.

P-glycoprotein modulates aldosterone plasma disposition and tissue uptake.

Parker RB, Yates CR, Laizure SC, Weber KT.

J Cardiovasc Pharmacol. 2006 Jan;47(1):55-9.

PMID:
16424786
50.

Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury.

Gao L, Grant A, Halder I, Brower R, Sevransky J, Maloney JP, Moss M, Shanholtz C, Yates CR, Meduri GU, Shriver MD, Ingersoll R, Scott AF, Beaty TH, Moitra J, Ma SF, Ye SQ, Barnes KC, Garcia JG.

Am J Respir Cell Mol Biol. 2006 Apr;34(4):487-95. Epub 2006 Jan 6.

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