Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 80

1.

Genome-Wide Overexpression Screen Identifies Genes Able to Bypass p16-Mediated Senescence in Melanoma.

Lee WJ, Škalamera D, Dahmer-Heath M, Shakhbazov K, Ranall MV, Fox C, Lambie D, Stevenson AJ, Yaswen P, Gonda TJ, Gabrielli B.

SLAS Discov. 2017 Mar;22(3):298-308. doi: 10.1177/1087057116679592. Epub 2016 Nov 23.

2.

PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression.

Horiuchi D, Camarda R, Zhou AY, Yau C, Momcilovic O, Balakrishnan S, Corella AN, Eyob H, Kessenbrock K, Lawson DA, Marsh LA, Anderton BN, Rohrberg J, Kunder R, Bazarov AV, Yaswen P, McManus MT, Rugo HS, Werb Z, Goga A.

Nat Med. 2016 Nov;22(11):1321-1329. doi: 10.1038/nm.4213. Epub 2016 Oct 24.

3.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Block KI, Gyllenhaal C, Lowe L, Amedei A, Amin ARMR, Amin A, Aquilano K, Arbiser J, Arreola A, Arzumanyan A, Ashraf SS, Azmi AS, Benencia F, Bhakta D, Bilsland A, Bishayee A, Blain SW, Block PB, Boosani CS, Carey TE, Carnero A, Carotenuto M, Casey SC, Chakrabarti M, Chaturvedi R, Chen GZ, Chen H, Chen S, Chen YC, Choi BK, Ciriolo MR, Coley HM, Collins AR, Connell M, Crawford S, Curran CS, Dabrosin C, Damia G, Dasgupta S, DeBerardinis RJ, Decker WK, Dhawan P, Diehl AME, Dong JT, Dou QP, Drew JE, Elkord E, El-Rayes B, Feitelson MA, Felsher DW, Ferguson LR, Fimognari C, Firestone GL, Frezza C, Fujii H, Fuster MM, Generali D, Georgakilas AG, Gieseler F, Gilbertson M, Green MF, Grue B, Guha G, Halicka D, Helferich WG, Heneberg P, Hentosh P, Hirschey MD, Hofseth LJ, Holcombe RF, Honoki K, Hsu HY, Huang GS, Jensen LD, Jiang WG, Jones LW, Karpowicz PA, Keith WN, Kerkar SP, Khan GN, Khatami M, Ko YH, Kucuk O, Kulathinal RJ, Kumar NB, Kwon BS, Le A, Lea MA, Lee HY, Lichtor T, Lin LT, Locasale JW, Lokeshwar BL, Longo VD, Lyssiotis CA, MacKenzie KL, Malhotra M, Marino M, Martinez-Chantar ML, Matheu A, Maxwell C, McDonnell E, Meeker AK, Mehrmohamadi M, Mehta K, Michelotti GA, Mohammad RM, Mohammed SI, Morre DJ, Muralidhar V, Muqbil I, Murphy MP, Nagaraju GP, Nahta R, Niccolai E, Nowsheen S, Panis C, Pantano F, Parslow VR, Pawelec G, Pedersen PL, Poore B, Poudyal D, Prakash S, Prince M, Raffaghello L, Rathmell JC, Rathmell WK, Ray SK, Reichrath J, Rezazadeh S, Ribatti D, Ricciardiello L, Robey RB, Rodier F, Rupasinghe HPV, Russo GL, Ryan EP, Samadi AK, Sanchez-Garcia I, Sanders AJ, Santini D, Sarkar M, Sasada T, Saxena NK, Shackelford RE, Shantha Kumara HMC, Sharma D, Shin DM, Sidransky D, Siegelin MD, Signori E, Singh N, Sivanand S, Sliva D, Smythe C, Spagnuolo C, Stafforini DM, Stagg J, Subbarayan PR, Sundin T, Talib WH, Thompson SK, Tran PT, Ungefroren H, Vander Heiden MG, Venkateswaran V, Vinay DS, Vlachostergios PJ, Wang Z, Wellen KE, Whelan RL, Yang ES, Yang H, Yang X, Yaswen P, Yedjou C, Yin X, Zhu J, Zollo M.

Semin Cancer Biol. 2015 Dec;35 Suppl:S276-S304. doi: 10.1016/j.semcancer.2015.09.007. Review.

4.

Parabens and Human Epidermal Growth Factor Receptor Ligand Cross-Talk in Breast Cancer Cells.

Pan S, Yuan C, Tagmount A, Rudel RA, Ackerman JM, Yaswen P, Vulpe CD, Leitman DC.

Environ Health Perspect. 2016 May;124(5):563-9. doi: 10.1289/ehp.1409200. Epub 2015 Oct 27.

5.

A TORC2-Akt Feed-Forward Topology Underlies HER3 Resiliency in HER2-Amplified Cancers.

Amin DN, Ahuja D, Yaswen P, Moasser MM.

Mol Cancer Ther. 2015 Dec;14(12):2805-17. doi: 10.1158/1535-7163.MCT-15-0403. Epub 2015 Oct 5.

6.

Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells.

Lawson DA, Bhakta NR, Kessenbrock K, Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY, Yaswen P, Goga A, Werb Z.

Nature. 2015 Oct 1;526(7571):131-5. doi: 10.1038/nature15260. Epub 2015 Sep 23.

7.

Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias.

Hines WC, Yaswen P, Bissell MJ.

Nat Commun. 2015 Apr 21;6:6927. doi: 10.1038/ncomms7927.

8.

Therapeutic targeting of replicative immortality.

Yaswen P, MacKenzie KL, Keith WN, Hentosh P, Rodier F, Zhu J, Firestone GL, Matheu A, Carnero A, Bilsland A, Sundin T, Honoki K, Fujii H, Georgakilas AG, Amedei A, Amin A, Helferich B, Boosani CS, Guha G, Ciriolo MR, Chen S, Mohammed SI, Azmi AS, Bhakta D, Halicka D, Niccolai E, Aquilano K, Ashraf SS, Nowsheen S, Yang X.

Semin Cancer Biol. 2015 Dec;35 Suppl:S104-S128. doi: 10.1016/j.semcancer.2015.03.007. Epub 2015 Apr 11. Review.

9.

Reinforcing targeted therapeutics with phenotypic stability factors.

Yaswen P.

Cell Cycle. 2014;13(24):3818-22. doi: 10.4161/15384101.2014.985071.

10.

ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium.

Nguyen-Ngoc KV, Cheung KJ, Brenot A, Shamir ER, Gray RS, Hines WC, Yaswen P, Werb Z, Ewald AJ.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):E2595-604. Epub 2012 Aug 23.

11.

Age-associated gene expression in normal breast tissue mirrors qualitative age-at-incidence patterns for breast cancer.

Pirone JR, D'Arcy M, Stewart DA, Hines WC, Johnson M, Gould MN, Yaswen P, Jerry DJ, Smith Schneider S, Troester MA.

Cancer Epidemiol Biomarkers Prev. 2012 Oct;21(10):1735-44. doi: 10.1158/1055-9965.EPI-12-0451. Epub 2012 Aug 2.

12.

The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression.

Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, Sweeney CA, Collins CC, Gray JW, Chang HY, Werb Z.

Cancer Discov. 2012 Jul;2(7):638-51. doi: 10.1158/2159-8290.CD-12-0093. Epub 2012 May 10.

13.

MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition.

Horiuchi D, Kusdra L, Huskey NE, Chandriani S, Lenburg ME, Gonzalez-Angulo AM, Creasman KJ, Bazarov AV, Smyth JW, Davis SE, Yaswen P, Mills GB, Esserman LJ, Goga A.

J Exp Med. 2012 Apr 9;209(4):679-96. doi: 10.1084/jem.20111512. Epub 2012 Mar 19.

14.

The specific role of pRb in p16 (INK4A) -mediated arrest of normal and malignant human breast cells.

Bazarov AV, Lee WJ, Bazarov I, Bosire M, Hines WC, Stankovich B, Chicas A, Lowe SW, Yaswen P.

Cell Cycle. 2012 Mar 1;11(5):1008-13. doi: 10.4161/cc.11.5.19492. Epub 2012 Mar 1.

15.

A tumor-suppressing function in the epithelial adhesion protein Trask.

Spassov DS, Wong CH, Harris G, McDonough S, Phojanakong P, Wang D, Hann B, Bazarov AV, Yaswen P, Khanafshar E, Moasser MM.

Oncogene. 2012 Jan 26;31(4):419-31. doi: 10.1038/onc.2011.246. Epub 2011 Jun 27.

16.

Who is in the driver's seat in 8p12 amplifications? ZNF703 in luminal B breast tumors.

Bazarov AV, Yaswen P.

Breast Cancer Res. 2011 May 25;13(3):308. doi: 10.1186/bcr2873.

17.

Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo.

Beliveau A, Mott JD, Lo A, Chen EI, Koller AA, Yaswen P, Muschler J, Bissell MJ.

Genes Dev. 2010 Dec 15;24(24):2800-11. doi: 10.1101/gad.1990410.

19.

HDAC inhibitors conquer Polycomb proteins.

Yaswen P.

Cell Cycle. 2010 Jul 15;9(14):2705. Epub 2010 Jul 15. No abstract available.

PMID:
20676029
20.

ZNF217, a candidate breast cancer oncogene amplified at 20q13, regulates expression of the ErbB3 receptor tyrosine kinase in breast cancer cells.

Krig SR, Miller JK, Frietze S, Beckett LA, Neve RM, Farnham PJ, Yaswen PI, Sweeney CA.

Oncogene. 2010 Oct 7;29(40):5500-10. doi: 10.1038/onc.2010.289. Epub 2010 Jul 26.

21.

p16(INK4a) -mediated suppression of telomerase in normal and malignant human breast cells.

Bazarov AV, Van Sluis M, Hines WC, Bassett E, Beliveau A, Campeau E, Mukhopadhyay R, Lee WJ, Melodyev S, Zaslavsky Y, Lee L, Rodier F, Chicas A, Lowe SW, Benhattar J, Ren B, Campisi J, Yaswen P.

Aging Cell. 2010 Oct;9(5):736-46. doi: 10.1111/j.1474-9726.2010.00599.x. Epub 2010 Jul 14.

22.

BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas.

Hines WC, Bazarov AV, Mukhopadhyay R, Yaswen P.

PLoS One. 2010 Mar 17;5(3):e9738. doi: 10.1371/journal.pone.0009738.

23.

Multidimensional profiling of cell surface proteins and nuclear markers.

Han J, Chang H, Andarawewa K, Yaswen P, Barcellos-Hoff MH, Parvin B.

IEEE/ACM Trans Comput Biol Bioinform. 2010 Jan-Mar;7(1):80-90. doi: 10.1109/TCBB.2008.134.

PMID:
20150670
24.

Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies.

Mukhopadhyay R, Costes SV, Bazarov AV, Hines WC, Barcellos-Hoff MH, Yaswen P.

Breast Cancer Res. 2010;12(1):R11. doi: 10.1186/bcr2477. Epub 2010 Feb 10.

25.

Telomerase activation by c-Myc in human mammary epithelial cells requires additional genomic changes.

Bazarov AV, Hines WC, Mukhopadhyay R, Beliveau A, Melodyev S, Zaslavsky Y, Yaswen P.

Cell Cycle. 2009 Oct 15;8(20):3373-8. Epub 2009 Oct 19.

PMID:
19806010
26.

A versatile viral system for expression and depletion of proteins in mammalian cells.

Campeau E, Ruhl VE, Rodier F, Smith CL, Rahmberg BL, Fuss JO, Campisi J, Yaswen P, Cooper PK, Kaufman PD.

PLoS One. 2009 Aug 6;4(8):e6529. doi: 10.1371/journal.pone.0006529.

27.

Aging and cancer cell biology, 2009.

Campisi J, Yaswen P.

Aging Cell. 2009 Jun;8(3):221-5. doi: 10.1111/j.1474-9726.2009.00475.x. Epub 2009 Mar 27. Review.

28.

Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells.

Fournier MV, Fata JE, Martin KJ, Yaswen P, Bissell MJ.

Cancer Res. 2009 May 15;69(10):4545-52. doi: 10.1158/0008-5472.CAN-08-1694. Epub 2009 May 5.

29.

Amplification of zinc finger gene 217 (ZNF217) and cancer: when good fingers go bad.

Quinlan KG, Verger A, Yaswen P, Crossley M.

Biochim Biophys Acta. 2007 Jun;1775(2):333-40. Epub 2007 May 22. Review.

PMID:
17572303
30.

Soothing the watchman: telomerase reduces the p53-dependent cellular stress response.

Beliveau A, Yaswen P.

Cell Cycle. 2007 Jun 1;6(11):1284-7. Epub 2007 Jun 13. Review.

31.

p53-dependent integration of telomere and growth factor deprivation signals.

Beliveau A, Bassett E, Lo AT, Garbe J, Rubio MA, Bissell MJ, Campisi J, Yaswen P.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4431-6. Epub 2007 Mar 5.

32.

Identification of genes directly regulated by the oncogene ZNF217 using chromatin immunoprecipitation (ChIP)-chip assays.

Krig SR, Jin VX, Bieda MC, O'Geen H, Yaswen P, Green R, Farnham PJ.

J Biol Chem. 2007 Mar 30;282(13):9703-12. Epub 2007 Jan 26.

33.

Oncogene-induced senescence pathways weave an intricate tapestry.

Yaswen P, Campisi J.

Cell. 2007 Jan 26;128(2):233-4. Review.

34.

Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins.

Quinlan KG, Nardini M, Verger A, Francescato P, Yaswen P, Corda D, Bolognesi M, Crossley M.

Mol Cell Biol. 2006 Nov;26(21):8159-72. Epub 2006 Aug 28.

35.

Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer.

Fournier MV, Martin KJ, Kenny PA, Xhaja K, Bosch I, Yaswen P, Bissell MJ.

Cancer Res. 2006 Jul 15;66(14):7095-102.

36.

ZNF217 suppresses cell death associated with chemotherapy and telomere dysfunction.

Huang G, Krig S, Kowbel D, Xu H, Hyun B, Volik S, Feuerstein B, Mills GB, Stokoe D, Yaswen P, Collins C.

Hum Mol Genet. 2005 Nov 1;14(21):3219-25. Epub 2005 Oct 3.

PMID:
16203743
37.

Cancer and aging: the importance of telomeres in genome maintenance.

Rodier F, Kim SH, Nijjar T, Yaswen P, Campisi J.

Int J Biochem Cell Biol. 2005 May;37(5):977-90. Epub 2005 Jan 4. Review.

PMID:
15743672
38.

Accumulation and altered localization of telomere-associated protein TRF2 in immortally transformed and tumor-derived human breast cells.

Nijjar T, Bassett E, Garbe J, Takenaka Y, Stampfer MR, Gilley D, Yaswen P.

Oncogene. 2005 May 5;24(20):3369-76.

PMID:
15735711
39.

In situ analyses of genome instability in breast cancer.

Chin K, de Solorzano CO, Knowles D, Jones A, Chou W, Rodriguez EG, Kuo WL, Ljung BM, Chew K, Myambo K, Miranda M, Krig S, Garbe J, Stampfer M, Yaswen P, Gray JW, Lockett SJ.

Nat Genet. 2004 Sep;36(9):984-8. Epub 2004 Aug 8.

PMID:
15300252
40.

Culture models of human mammary epithelial cell transformation.

Stampfer MR, Yaswen P.

J Mammary Gland Biol Neoplasia. 2000 Oct;5(4):365-78. Review.

PMID:
14973382
41.

Loss of p53 function accelerates acquisition of telomerase activity in indefinite lifespan human mammary epithelial cell lines.

Stampfer MR, Garbe J, Nijjar T, Wigington D, Swisshelm K, Yaswen P.

Oncogene. 2003 Aug 14;22(34):5238-51.

PMID:
12917625
42.

Reversal of human cellular senescence: roles of the p53 and p16 pathways.

Beauséjour CM, Krtolica A, Galimi F, Narita M, Lowe SW, Yaswen P, Campisi J.

EMBO J. 2003 Aug 15;22(16):4212-22.

43.

Human epithelial cell immortalization as a step in carcinogenesis.

Stampfer MR, Yaswen P.

Cancer Lett. 2003 May 15;194(2):199-208. Review.

PMID:
12757978
44.
45.

Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells.

Yaswen P, Stampfer MR.

Int J Biochem Cell Biol. 2002 Nov;34(11):1382-94. Review.

PMID:
12200033
46.

Crystal structure of human calmodulin-like protein: insights into its functional role.

Han BG, Han M, Sui H, Yaswen P, Walian PJ, Jap BK.

FEBS Lett. 2002 Jun 19;521(1-3):24-30.

47.

Epigenetic changes accompanying human mammary epithelial cell immortalization.

Yaswen P, Stampfer MR.

J Mammary Gland Biol Neoplasia. 2001 Apr;6(2):223-34. Review.

PMID:
11501582
48.

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression.

Kaminker PG, Kim SH, Taylor RD, Zebarjadian Y, Funk WD, Morin GB, Yaswen P, Campisi J.

J Biol Chem. 2001 Sep 21;276(38):35891-9. Epub 2001 Jul 13.

49.

Monitoring signal transduction in cancer: tyrosine kinase gene expression profiling.

Weier HU, Zitzelsberger HF, Hsieh HB, Sun MV, Wong M, Lersch RA, Yaswen P, Smida J, Kuschnick C, Clark OH.

J Histochem Cytochem. 2001 May;49(5):673-4.

PMID:
11304810
50.

Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells.

Stampfer MR, Garbe J, Levine G, Lichtsteiner S, Vasserot AP, Yaswen P.

Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4498-503. Epub 2001 Apr 3.

Supplemental Content

Loading ...
Support Center