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Identification of a Key Enzyme for the Hydrolysis of β-(1→3)-Xylosyl Linkage in Red Alga Dulse Xylooligosaccharide from Bifidobacterium Adolescentis.

Kobayashi M, Kumagai Y, Yamamoto Y, Yasui H, Kishimura H.

Mar Drugs. 2020 Mar 20;18(3). pii: E174. doi: 10.3390/md18030174.


[Imaging of Tumor-Specific Hypoxia Dynamics and Its Significance in Radiation Biology].

Yasui H, Matsumoto S, Inanami O, Krishna MC.

Igaku Butsuri. 2020;40(1):13-18. doi: 10.11323/jjmp.40.1_13. Japanese.


Effects of exercise on biological trace element concentrations and selenoprotein P expression in rats with fructose-induced glucose intolerance.

Miya N, Uratani A, Chikamoto K, Naito Y, Terao K, Yoshikawa Y, Yasui H.

J Clin Biochem Nutr. 2020 Mar;66(2):124-131. doi: 10.3164/jcbn.19-96. Epub 2020 Jan 17.


Randomized, Phase II Study of Trastuzumab Beyond Progression in Patients With HER2-Positive Advanced Gastric or Gastroesophageal Junction Cancer: WJOG7112G (T-ACT Study).

Makiyama A, Sukawa Y, Kashiwada T, Kawada J, Hosokawa A, Horie Y, Tsuji A, Moriwaki T, Tanioka H, Shinozaki K, Uchino K, Yasui H, Tsukuda H, Nishikawa K, Ishida H, Yamanaka T, Yamazaki K, Hironaka S, Esaki T, Boku N, Hyodo I, Muro K.

J Clin Oncol. 2020 Mar 24:JCO1903077. doi: 10.1200/JCO.19.03077. [Epub ahead of print]


In Silico Analysis of ACE Inhibitory Peptides from Chloroplast Proteins of Red Alga Grateloupia asiatica.

Sumikawa K, Takei K, Kumagai Y, Shimizu T, Yasui H, Kishimura H.

Mar Biotechnol (NY). 2020 Mar 24. doi: 10.1007/s10126-020-09959-2. [Epub ahead of print]


Intravoxel incoherent motion magnetic resonance imaging for predicting the long-term efficacy of immune checkpoint inhibitors in patients with non-small-cell lung cancer.

Karayama M, Yoshizawa N, Sugiyama M, Mori K, Yasui H, Hozumi H, Suzuki Y, Furuhashi K, Fujisawa T, Enomoto N, Nakamura Y, Inui N, Goshima S, Suda T, Takehara Y.

Lung Cancer. 2020 Mar 18;143:47-54. doi: 10.1016/j.lungcan.2020.03.013. [Epub ahead of print]


Prediction of S-1 adjuvant chemotherapy benefit in Stage II/III gastric cancer treatment based on comprehensive gene expression analysis.

Nakamura K, Hatakeyama K, Furukawa K, Fujiya K, Kamiya S, Hikage M, Tanizawa Y, Bando E, Ohshima K, Urakami K, Machida N, Yasui H, Yamaguchi K, Terashima M.

Gastric Cancer. 2020 Mar 18. doi: 10.1007/s10120-020-01056-6. [Epub ahead of print]


Long-term efficacy and predictive correlates of response to nivolumab in Japanese patients with esophageal cancer.

Kato K, Doki Y, Ura T, Hamamoto Y, Kojima T, Tsushima T, Hironaka S, Hara H, Kudo T, Iwasa S, Muro K, Yasui H, Minashi K, Yamaguchi K, Ohtsu A, Kitagawa Y.

Cancer Sci. 2020 Mar 11. doi: 10.1111/cas.14380. [Epub ahead of print]


Safety and efficacy of pembrolizumab in combination with S-1 plus oxaliplatin as a first-line treatment in patients with advanced gastric/gastroesophageal junction cancer: Cohort 1 data from the KEYNOTE-659 phase IIb study.

Kawazoe A, Yamaguchi K, Yasui H, Negoro Y, Azuma M, Amagai K, Hara H, Baba H, Tsuda M, Hosaka H, Kawakami H, Oshima T, Omuro Y, Machida N, Esaki T, Yoshida K, Nishina T, Komatsu Y, Han SR, Shiratori S, Shitara K.

Eur J Cancer. 2020 Apr;129:97-106. doi: 10.1016/j.ejca.2020.02.002. Epub 2020 Mar 4.


Risk factors for aspiration pneumonia during concurrent chemoradiotherapy or bio-radiotherapy for head and neck cancer.

Shirasu H, Yokota T, Hamauchi S, Onozawa Y, Ogawa H, Onoe T, Onitsuka T, Yurikusa T, Mori K, Yasui H.

BMC Cancer. 2020 Mar 4;20(1):182. doi: 10.1186/s12885-020-6682-1.


FTY720 Protects Against Ischemia-Reperfusion Injury by Preventing the Redistribution of Tight Junction Proteins and Decreases Inflammation in the Subacute Phase in an Experimental Stroke Model.

Wang Z, Higashikawa K, Yasui H, Kuge Y, Ohno Y, Kihara A, Midori YA, Houkin K, Kawabori M.

Transl Stroke Res. 2020 Feb 27. doi: 10.1007/s12975-020-00789-x. [Epub ahead of print]


Safety and effectiveness of direct oral anticoagulants for venous thromboembolism in patients with active cancer: a retrospective study.

Ogata M, Satake H, Ama Y, Hirabatake M, Ogata T, Yasui H, Hashida T.

Ann Oncol. 2019 Jul;30 Suppl 4:iv45. doi: 10.1093/annonc/mdz155.164. Epub 2019 Dec 4. No abstract available.


Author Correction: Macrophage Mannose Receptor CD206 Predicts Prognosis in Community-acquired Pneumonia.

Tsuchiya K, Suzuki Y, Yoshimura K, Yasui H, Karayama M, Hozumi H, Furuhashi K, Enomoto N, Fujisawa T, Nakamura Y, Inui N, Yokomura K, Suda T.

Sci Rep. 2020 Feb 19;10(1):3324. doi: 10.1038/s41598-020-58958-9.


Pulse oximetric saturation to fraction of inspired oxygen (SpO2/FIO2) ratio 24 hours after high-flow nasal cannula (HFNC) initiation is a good predictor of HFNC therapy in patients with acute exacerbation of interstitial lung disease.

Koyauchi T, Yasui H, Enomoto N, Hasegawa H, Hozumi H, Suzuki Y, Karayama M, Furuhashi K, Fujisawa T, Nakamura Y, Inui N, Yokomura K, Suda T.

Ther Adv Respir Dis. 2020 Jan-Dec;14:1753466620906327. doi: 10.1177/1753466620906327.


Pre-treatment tumor size impacts on response to nivolumab in head and neck squamous cell carcinoma.

Inoue H, Yokota T, Hamauchi S, Onozawa Y, Kawakami T, Shirasu H, Notsu A, Yasui H, Onitsuka T.

Auris Nasus Larynx. 2020 Feb 5. pii: S0385-8146(20)30023-7. doi: 10.1016/j.anl.2020.01.003. [Epub ahead of print]


Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer.

Isobe Y, Sato K, Nishinaga Y, Takahashi K, Taki S, Yasui H, Shimizu M, Endo R, Koike C, Kuramoto N, Yukawa H, Nakamura S, Fukui T, Kawaguchi K, Chen-Yoshikawa TF, Baba Y, Hasegawa Y.

EBioMedicine. 2020 Feb;52:102632. doi: 10.1016/j.ebiom.2020.102632. Epub 2020 Jan 23.


Ovarian cancer-associated mesothelial cells induce acquired platinum-resistance in peritoneal metastasis via the FN1/Akt signaling pathway.

Yoshihara M, Kajiyama H, Yokoi A, Sugiyama M, Koya Y, Yamakita Y, Liu W, Nakamura K, Moriyama Y, Yasui H, Suzuki S, Yamamoto Y, Ricciardelli C, Nawa A, Shibata K, Kikkawa F.

Int J Cancer. 2020 Apr 15;146(8):2268-2280. doi: 10.1002/ijc.32854. Epub 2020 Jan 24.


Suppressive Effects of Hot-water Extract of Magnolia obovata on Clostridium perfringens Enterotoxin-induced Cytotoxicity in Human Intestinal Caco-2 Cells.

Kawahara T, Fujii K, Nakajima K, Fujii R, Inagaki S, Hara K, Yasui H.

Planta Med. 2020 Feb;86(3):198-204. doi: 10.1055/a-1078-7860. Epub 2020 Jan 2.


Hepatic Arterial Infusion Chemotherapy for Metastatic Breast Cancer Patients With Resistance to Standard Systemic Chemotherapies.

Furuta M, Watanabe J, Aramaki T, Notsu A, Yasui H.

In Vivo. 2020 Jan-Feb;34(1):275-282. doi: 10.21873/invivo.11771.


Preclinical investigation of potential use of thymidine phosphorylase-targeting tracer for diagnosis of nonalcoholic steatohepatitis.

Higashikawa K, Horiguchi S, Tarisawa M, Shibata Y, Ohkura K, Yasui H, Takeda H, Kuge Y.

Nucl Med Biol. 2019 Dec 16;82-83:25-32. doi: 10.1016/j.nucmedbio.2019.12.006. [Epub ahead of print]


The Safety and Survival Outcome of Hepatectomy with Combined Bile Duct Resection for Colorectal Liver Metastasis.

Ito T, Sugiura T, Okamura Y, Yamamoto Y, Ashida R, Ohgi K, Yasui H, Yamazaki K, Uesaka K.

World J Surg. 2020 Apr;44(4):1231-1243. doi: 10.1007/s00268-019-05326-y.


A simplified method for therapeutic drug monitoring of mitotane by gas chromatography-electron ionization-mass spectrometry.

Ando M, Hirabatake M, Yasui H, Fukushima S, Sugioka N, Hashida T.

Biomed Chromatogr. 2020 Mar;34(3):e4776. doi: 10.1002/bmc.4776. Epub 2020 Jan 28.


Macrophage Mannose Receptor CD206 Predicts Prognosis in Community-acquired Pneumonia.

Tsuchiya K, Suzuki Y, Yoshimura K, Yasui H, Karayama M, Hozumi H, Furuhashi K, Enomoto N, Fujisawa T, Nakamura Y, Inui N, Yokomura K, Suda T.

Sci Rep. 2019 Dec 10;9(1):18750. doi: 10.1038/s41598-019-55289-2. Erratum in: Sci Rep. 2020 Feb 19;10(1):3324.


Erastin, a ferroptosis-inducing agent, sensitized cancer cells to X-ray irradiation via glutathione starvation in vitro and in vivo.

Shibata Y, Yasui H, Higashikawa K, Miyamoto N, Kuge Y.

PLoS One. 2019 Dec 4;14(12):e0225931. doi: 10.1371/journal.pone.0225931. eCollection 2019.


Mitochondrial fission promotes radiation-induced increase in intracellular Ca2+ level leading to mitotic catastrophe in mouse breast cancer EMT6 cells.

Bo T, Yamamori T, Yamamoto K, Fujimoto M, Yasui H, Inanami O.

Biochem Biophys Res Commun. 2020 Jan 29;522(1):144-150. doi: 10.1016/j.bbrc.2019.11.027. Epub 2019 Nov 19.


The Development and Characterization of Near-Isogenic and Pyramided Lines Carrying Resistance Genes to Brown Planthopper with the Genetic Background of Japonica Rice (Oryza sativa L.).

Nguyen CD, Verdeprado H, Zita D, Sanada-Morimura S, Matsumura M, Virk PS, Brar DS, Horgan FG, Yasui H, Fujita D.

Plants (Basel). 2019 Nov 12;8(11). pii: E498. doi: 10.3390/plants8110498.


Prognostic factors for primary Sjögren's syndrome-associated interstitial lung diseases.

Kamiya Y, Fujisawa T, Kono M, Nakamura H, Yokomura K, Koshimizu N, Toyoshima M, Imokawa S, Sumikawa H, Johkoh T, Yasui H, Hozumi H, Suzuki Y, Karayama M, Furuhashi K, Enomoto N, Nakamura Y, Inui N, Suda T.

Respir Med. 2019 Nov;159:105811. doi: 10.1016/j.rmed.2019.105811. Epub 2019 Nov 5.


Exfiltration and infiltration effect on sewage flow and quality: a case study of Hue, Vietnam.

Watanabe R, Harada H, Yasui H, Le TV, Fujii S.

Environ Technol. 2019 Oct 28:1-11. doi: 10.1080/09593330.2019.1680739. [Epub ahead of print]


High drug efflux pump capacity and low DNA damage response induce doxorubicin resistance in canine hemangiosarcoma cell lines.

Morita A, Aoshima K, Gulay KCM, Onishi S, Shibata Y, Yasui H, Kobayashi A, Kimura T.

Res Vet Sci. 2019 Dec;127:1-10. doi: 10.1016/j.rvsc.2019.09.011. Epub 2019 Oct 17.


Pretreatment predictive factors for feasibility of oral intake in adjuvant concurrent chemoradiotherapy for patients with locally advanced squamous cell carcinoma of the head and neck.

Kimura H, Hamauchi S, Kawai S, Onozawa Y, Yasui H, Yamashita A, Ogawa H, Onoe T, Kamijo T, Iida Y, Onitsuka T, Yokota T.

Int J Clin Oncol. 2020 Feb;25(2):258-266. doi: 10.1007/s10147-019-01560-5. Epub 2019 Oct 16.


Ligand-Independent EGFR Activation by Anchorage-Stimulated Src Promotes Cancer Cell Proliferation and Cetuximab Resistance via ErbB3 Phosphorylation.

Nozaki M, Yasui H, Ohnishi Y.

Cancers (Basel). 2019 Oct 14;11(10). pii: E1552. doi: 10.3390/cancers11101552.


High-resolution mapping of GRH6, a gene from Oryza nivara (Sharma et Shastry) conferring resistance to green rice leafhopper (Nephotettix cincticeps Uhler).

Phi CN, Fujita D, Yamagata Y, Yoshimura A, Yasui H.

Breed Sci. 2019 Sep;69(3):439-446. doi: 10.1270/jsbbs.19029. Epub 2019 Jun 27.


Clinical significance of serum S100 calcium-binding protein A4 in idiopathic pulmonary fibrosis.

Akiyama N, Hozumi H, Isayama T, Okada J, Sugiura K, Yasui H, Suzuki Y, Kono M, Karayama M, Furuhashi K, Enomoto N, Fujisawa T, Inui N, Nakamura Y, Suda T.

Respirology. 2019 Oct 9. doi: 10.1111/resp.13707. [Epub ahead of print]


Once-daily fluticasone furoate/vilanterol combination versus twice-daily budesonide/formoterol combination in the treatment of controlled stable asthma: a randomized crossover trial.

Furuhashi K, Fujisawa T, Hashimoto D, Kamiya Y, Yasui H, Karayama M, Suzuki Y, Hozumi H, Enomoto N, Nakamura Y, Inui N, Suda T.

J Asthma Allergy. 2019 Sep 17;12:253-261. doi: 10.2147/JAA.S223093. eCollection 2019. Review.


Identification of Anther Length QTL and Construction of Chromosome Segment Substitution Lines of Oryza longistaminata.

Ogami T, Yasui H, Yoshimura A, Yamagata Y.

Plants (Basel). 2019 Sep 29;8(10). pii: E388. doi: 10.3390/plants8100388.


Perspectives on the Use of Ninjin'yoeito in Modern Medicine: A Review of Randomized Controlled Trials.

Takayama S, Arita R, Ohsawa M, Kikuchi A, Yasui H, Makino T, Motoo Y, Ishii T.

Evid Based Complement Alternat Med. 2019 Sep 2;2019:9590260. doi: 10.1155/2019/9590260. eCollection 2019. Review.


Nucleoside analogs as a radiosensitizer modulating DNA repair, cell cycle checkpoints, and apoptosis.

Yasui H, Iizuka D, Hiraoka W, Kuwabara M, Matsuda A, Inanami O.

Nucleosides Nucleotides Nucleic Acids. 2019 Sep 27:1-14. doi: 10.1080/15257770.2019.1670839. [Epub ahead of print]


Pathological response measured using virtual microscopic slides for gastric cancer patients who underwent neoadjuvant chemotherapy.

Kawai S, Shimoda T, Nakajima T, Terashima M, Omae K, Machida N, Yasui H.

World J Gastroenterol. 2019 Sep 21;25(35):5334-5343. doi: 10.3748/wjg.v25.i35.5334.


CCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway.

Yasui H, Kajiyama H, Tamauchi S, Suzuki S, Peng Y, Yoshikawa N, Sugiyama M, Nakamura K, Kikkawa F.

Clin Exp Metastasis. 2020 Feb;37(1):145-158. doi: 10.1007/s10585-019-09993-y. Epub 2019 Sep 21.


Identification and Characterization of the Pheromones in the Minute Pirate Bug Orius sauteri (Heteroptera: Anthocoridae).

Uehara T, Maeda T, Shimoda M, Fujiwara-Tsujii N, Yasui H.

J Chem Ecol. 2019 Oct;45(10):811-817. doi: 10.1007/s10886-019-01104-1. Epub 2019 Sep 7.


Development of introgression lines of AA genome Oryza species, O. glaberrima, O. rufipogon, and O. nivara, in the genetic background of O. sativa L. cv. Taichung 65.

Yamagata Y, Win KT, Miyazaki Y, Ogata C, Yasui H, Yoshimura A.

Breed Sci. 2019 Jun;69(2):359-363. doi: 10.1270/jsbbs.19002. Epub 2019 May 18.


Prognostic impact of an early marginal decline in forced vital capacity in idiopathic pulmonary fibrosis patients treated with pirfenidone.

Kono M, Nakamura Y, Enomoto N, Saito G, Koyanagi Y, Miyashita K, Tsutsumi A, Kobayashi T, Yasui H, Hozumi H, Karayama M, Suzuki Y, Furuhashi K, Miki Y, Hashimoto D, Fujisawa T, Inui N, Suda T, Nakamura H.

Respir Investig. 2019 Nov;57(6):552-560. doi: 10.1016/j.resinv.2019.07.003. Epub 2019 Aug 31.


Body composition changes successfully classify prognosis in patients with mycobacterium avium complex lung disease.

Akahori D, Suzuki Y, Yokomura K, Shirai M, Yasui H, Hozumi H, Karayama M, Furuhashi K, Enomoto N, Fujisawa T, Nakamura Y, Inui N, Hayakawa H, Suda T.

J Infect. 2019 Oct;79(4):341-348. doi: 10.1016/j.jinf.2019.07.014. Epub 2019 Jul 31.


Soluble SLAMF7 promotes the growth of myeloma cells via homophilic interaction with surface SLAMF7.

Kikuchi J, Hori M, Iha H, Toyama-Sorimachi N, Hagiwara S, Kuroda Y, Koyama D, Izumi T, Yasui H, Suzuki A, Furukawa Y.

Leukemia. 2020 Jan;34(1):180-195. doi: 10.1038/s41375-019-0525-6. Epub 2019 Jul 29.


Antioxidant activity of proteins extracted from red alga dulse harvested in Japan.

Sato N, Furuta T, Takeda T, Miyabe Y, Ura K, Takagi Y, Yasui H, Kumagai Y, Kishimura H.

J Food Biochem. 2019 Feb;43(2):e12709. doi: 10.1111/jfbc.12709. Epub 2018 Oct 29.


Simultaneous Occurrence of Sarcoidosis and Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis in a Patient with Lung Cancer.

Tsuchiya K, Karayama M, Sato T, Yasui H, Hozumi H, Suzuki Y, Furuhashi K, Enomoto N, Fujisawa T, Nakamura Y, Inui N, Sugimura H, Yasuda H, Suda T.

Intern Med. 2019 Nov 15;58(22):3299-3304. doi: 10.2169/internalmedicine.3004-19. Epub 2019 Jul 22.


Reduction and Escalation in the Dose of Sunitinib Were Adequately Effective against Gastrointestinal Stromal Tumor of the Small Intestine.

Ogata M, Satake H, Ogata T, Hatachi Y, Hara S, Hirota S, Yasui H.

Intern Med. 2019 Nov 15;58(22):3243-3246. doi: 10.2169/internalmedicine.2806-19. Epub 2019 Jul 22.


Minute Pulmonary Meningothelial-like Nodules Showing Multiple Ring-shaped Opacities.

Harada M, Aono Y, Yasui H, Uto T, Sato J, Imokawa S, Suzuki S, Tanioka F, Suda T.

Intern Med. 2019 Nov 1;58(21):3149-3152. doi: 10.2169/internalmedicine.2108-18. Epub 2019 Jul 22. Review.


Analysis of serum adiponectin and leptin in patients with acute exacerbation of idiopathic pulmonary fibrosis.

Enomoto N, Oyama Y, Yasui H, Karayama M, Hozumi H, Suzuki Y, Kono M, Furuhashi K, Fujisawa T, Inui N, Nakamura Y, Suda T.

Sci Rep. 2019 Jul 19;9(1):10484. doi: 10.1038/s41598-019-46990-3.

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