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Karyopherin Alpha 2-Expressing Pancreatic Duct Glands and Intra-Islet Ducts in Aged Diabetic C414A-Mutant-CRY1 Transgenic Mice.

Okano S, Yasui A, Kanno SI, Satoh K, Igarashi M, Nakajima O.

J Diabetes Res. 2019 Apr 24;2019:7234549. doi: 10.1155/2019/7234549. eCollection 2019.


Safety and Efficacy of Empagliflozin as Add-On Therapy to GLP-1 Receptor Agonist (Liraglutide) in Japanese Patients with Type 2 Diabetes Mellitus: A Randomised, Double-Blind, Parallel-Group Phase 4 Study.

Terauchi Y, Utsunomiya K, Yasui A, Seki T, Cheng G, Shiki K, Lee J.

Diabetes Ther. 2019 Jun;10(3):951-963. doi: 10.1007/s13300-019-0604-8. Epub 2019 Mar 25.


RACK1 regulates centriole duplication by controlling localization of BRCA1 to the centrosome in mammary tissue-derived cells.

Yoshino Y, Qi H, Kanazawa R, Sugamata M, Suzuki K, Kobayashi A, Shindo K, Matsuzawa A, Shibata S, Endo S, Miyanishi Y, Shimaoka T, Ishioka C, Kanno SI, Yasui A, Chiba N.

Oncogene. 2019 Apr;38(16):3077-3092. doi: 10.1038/s41388-018-0647-8. Epub 2019 Jan 7.


DNMTs and SETDB1 function as co-repressors in MAX-mediated repression of germ cell-related genes in mouse embryonic stem cells.

Tatsumi D, Hayashi Y, Endo M, Kobayashi H, Yoshioka T, Kiso K, Kanno S, Nakai Y, Maeda I, Mochizuki K, Tachibana M, Koseki H, Okuda A, Yasui A, Kono T, Matsui Y.

PLoS One. 2018 Nov 7;13(11):e0205969. doi: 10.1371/journal.pone.0205969. eCollection 2018.


Realization of a scanning soft X-ray microscope for magnetic imaging under high magnetic fields.

Kotani Y, Senba Y, Toyoki K, Billington D, Okazaki H, Yasui A, Ueno W, Ohashi H, Hirosawa S, Shiratsuchi Y, Nakamura T.

J Synchrotron Radiat. 2018 Sep 1;25(Pt 5):1444-1449. doi: 10.1107/S1600577518009177. Epub 2018 Aug 2.


Safety and tolerability of empagliflozin in East Asian patients with type 2 diabetes: Pooled analysis of phase I-III clinical trials.

Yabe D, Yasui A, Ji L, Lee MK, Ma RCW, Chang TJ, Okamura T, Zeller C, Kaspers S, Lee J, Kohler S, Seino Y.

J Diabetes Investig. 2019 Mar;10(2):418-428. doi: 10.1111/jdi.12910. Epub 2018 Sep 20.


Efficacy of a dinotefuran, pyriproxyfen and permethrin combination product against Ctenocephalides felis felis (Bouché, 1835) (Siphonaptera: Pulicidae) on artificially infested rabbits.

Borges DA, Moraes PA, Cardoso JD, Oliveira PC, Yasui AM, Fernandes IMP, Lambert MM, Correia TR, Scott FB.

Vet Parasitol. 2018 Aug 15;259:74-79. doi: 10.1016/j.vetpar.2018.07.006. Epub 2018 Jul 17.


Electronic Structure of Ce-Doped and -Undoped Nd_{2}CuO_{4} Superconducting Thin Films Studied by Hard X-Ray Photoemission and Soft X-Ray Absorption Spectroscopy.

Horio M, Krockenberger Y, Yamamoto K, Yokoyama Y, Takubo K, Hirata Y, Sakamoto S, Koshiishi K, Yasui A, Ikenaga E, Shin S, Yamamoto H, Wadati H, Fujimori A.

Phys Rev Lett. 2018 Jun 22;120(25):257001. doi: 10.1103/PhysRevLett.120.257001.


Empagliflozin as adjunct to insulin in Japanese participants with type 1 diabetes: Results of a 4-week, double-blind, randomized, placebo-controlled phase 2 trial.

Shimada A, Hanafusa T, Yasui A, Lee G, Taneda Y, Sarashina A, Shiki K, George J, Soleymanlou N, Marquard J.

Diabetes Obes Metab. 2018 Sep;20(9):2190-2199. doi: 10.1111/dom.13351. Epub 2018 Jun 5.


Empagliflozin Induces Transient Diuresis Without Changing Long-Term Overall Fluid Balance in Japanese Patients With Type 2 Diabetes.

Yasui A, Lee G, Hirase T, Kaneko T, Kaspers S, von Eynatten M, Okamura T.

Diabetes Ther. 2018 Apr;9(2):863-871. doi: 10.1007/s13300-018-0385-5. Epub 2018 Feb 27.


ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair.

Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, Murai J, Hiraoka M, Koike K, Pommier Y, Takeda S, Hirota K.

PLoS One. 2017 Nov 17;12(11):e0188320. doi: 10.1371/journal.pone.0188320. eCollection 2017.


Nucleosome remodelling, DNA repair and transcriptional regulation build negative feedback loops in cancer and cellular ageing.

Watanabe R, Kanno SI, Mohammadi Roushandeh A, Ui A, Yasui A.

Philos Trans R Soc Lond B Biol Sci. 2017 Oct 5;372(1731). pii: 20160473. doi: 10.1098/rstb.2016.0473. Review.


DNA Polymerase Beta Participates in Mitochondrial DNA Repair.

Sykora P, Kanno S, Akbari M, Kulikowicz T, Baptiste BA, Leandro GS, Lu H, Tian J, May A, Becker KA, Croteau DL, Wilson DM 3rd, Sobol RW, Yasui A, Bohr VA.

Mol Cell Biol. 2017 Jul 28;37(16). pii: e00237-17. doi: 10.1128/MCB.00237-17. Print 2017 Aug 15.


Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair.

Ishida N, Nakagawa T, Iemura SI, Yasui A, Shima H, Katoh Y, Nagasawa Y, Natsume T, Igarashi K, Nakayama K.

Mol Cell Biol. 2017 Feb 1;37(4). pii: e00347-16. doi: 10.1128/MCB.00347-16. Print 2017 Feb 15.


Analysis of Azodicarbonamide in Wheat Flour and Prepared Flour Mixes.

Yasui A, Oishi M, Hayafuji C, Kobayashi C, Shindo T, Ozawa H, Nakazato M.

Shokuhin Eiseigaku Zasshi. 2016;57(5):133-138. Japanese.


Total Synthesis of Miuraenamides A and D.

Ojima D, Yasui A, Tohyama K, Tokuzumi K, Toriihara E, Ito K, Iwasaki A, Tomura T, Ojika M, Suenaga K.

J Org Chem. 2016 Oct 21;81(20):9886-9894. Epub 2016 Oct 3.


Retinal sensitivity after selective retina therapy (SRT) on patients with central serous chorioretinopathy.

Yasui A, Yamamoto M, Hirayama K, Shiraki K, Theisen-Kunde D, Brinkmann R, Miura Y, Kohno T.

Graefes Arch Clin Exp Ophthalmol. 2017 Feb;255(2):243-254. doi: 10.1007/s00417-016-3441-8. Epub 2016 Aug 6.


Unique food-entrained circadian rhythm in cysteine414-alanine mutant mCRY1 transgenic mice.

Okano S, Yasui A, Hayasaka K, Nakajima O.

Sleep Biol Rhythms. 2016;14:261-269. Epub 2016 Jan 29.


Collaboration of MLLT1/ENL, Polycomb and ATM for transcription and genome integrity.

Ui A, Yasui A.

Nucleus. 2016 Apr 25;7(2):138-45. doi: 10.1080/19491034.2016.1177681. Review.


Improvement and Interlaboratory Validation of the Lipophilic Oxygen Radical Absorbance Capacity: Determination of Antioxidant Capacities of Lipophilic Antioxidant Solutions and Food Extracts.

Watanabe J, Oki T, Takebayashi J, Yada H, Wagaki M, Takano-Ishikawa Y, Yasui A.

Anal Sci. 2016;32(2):171-5. doi: 10.2116/analsci.32.171.


Cytotoxicity and colloidal behavior of polystyrene latex nanoparticles toward filamentous fungi in isotonic solutions.

Nomura T, Tani S, Yamamoto M, Nakagawa T, Toyoda S, Fujisawa E, Yasui A, Konishi Y.

Chemosphere. 2016 Apr;149:84-90. doi: 10.1016/j.chemosphere.2016.01.091. Epub 2016 Feb 5.


Effect of dietary fibers on losartan uptake and transport in Caco-2 cells.

Iwazaki A, Takahashi N, Miyake R, Hiroshima Y, Abe M, Yasui A, Imai K.

Biopharm Drug Dispos. 2016 May;37(4):212-9. doi: 10.1002/bdd.2004. Epub 2016 Mar 31.


IMAGES IN CLINICAL MEDICINE. Oral Maxillary Exostosis.

Kitajima S, Yasui A.

N Engl J Med. 2015 Oct 8;373(15):1457. doi: 10.1056/NEJMicm1414626. No abstract available.


Modal variety of microsatellite instability in human endometrial carcinomas.

Eto T, Zhao Y, Maruyama A, Miyashita K, Yasui A, Nakao S, Taguchi K, Shimokawa M, Oda S, Saito T.

J Cancer Res Clin Oncol. 2016 Feb;142(2):353-63. doi: 10.1007/s00432-015-2030-2. Epub 2015 Aug 23.


Transcriptional elongation factor ENL phosphorylated by ATM recruits polycomb and switches off transcription for DSB repair.

Ui A, Nagaura Y, Yasui A.

Mol Cell. 2015 May 7;58(3):468-82. doi: 10.1016/j.molcel.2015.03.023. Epub 2015 Apr 23.


Role of isolated and clustered DNA damage and the post-irradiating repair process in the effects of heavy ion beam irradiation.

Tokuyama Y, Furusawa Y, Ide H, Yasui A, Terato H.

J Radiat Res. 2015 May;56(3):446-55. doi: 10.1093/jrr/rru122. Epub 2015 Feb 25.


Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylation.

Homma Y, Kanno S, Sasaki K, Nishita M, Yasui A, Asano T, Ohashi K, Mizuno K.

J Biol Chem. 2014 Sep 19;289(38):26302-13. doi: 10.1074/jbc.M114.565945. Epub 2014 Aug 6.


SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.

Watanabe R, Ui A, Kanno S, Ogiwara H, Nagase T, Kohno T, Yasui A.

Cancer Res. 2014 May 1;74(9):2465-75. doi: 10.1158/0008-5472.CAN-13-3608.


[A rapid dialysis method for analysis of artificial sweeteners in food].

Tahara S, Fujiwara T, Yasui A, Hayafuji C, Kobayashi C, Uematsu Y.

Shokuhin Eiseigaku Zasshi. 2014;55(1):13-8. Japanese.


Ubiquitin-specific protease 5 is required for the efficient repair of DNA double-strand breaks.

Nakajima S, Lan L, Wei L, Hsieh CL, Rapić-Otrin V, Yasui A, Levine AS.

PLoS One. 2014 Jan 14;9(1):e84899. doi: 10.1371/journal.pone.0084899. eCollection 2014.


The novel zinc finger protein dASCIZ regulates mitosis in Drosophila via an essential role in dynein light-chain expression.

Zaytseva O, Tenis N, Mitchell N, Kanno S, Yasui A, Heierhorst J, Quinn LM.

Genetics. 2014 Feb;196(2):443-53. doi: 10.1534/genetics.113.159541. Epub 2013 Dec 13.


Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin.

Lan L, Nakajima S, Wei L, Sun L, Hsieh CL, Sobol RW, Bruchez M, Van Houten B, Yasui A, Levine AS.

Nucleic Acids Res. 2014 Feb;42(4):2330-45. doi: 10.1093/nar/gkt1233. Epub 2013 Nov 29.


The BRCA1/BARD1-interacting protein OLA1 functions in centrosome regulation.

Matsuzawa A, Kanno S, Nakayama M, Mochiduki H, Wei L, Shimaoka T, Furukawa Y, Kato K, Shibata S, Yasui A, Ishioka C, Chiba N.

Mol Cell. 2014 Jan 9;53(1):101-14. doi: 10.1016/j.molcel.2013.10.028. Epub 2013 Nov 27.


Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitylation after degradation of poly(ADP-ribose).

Wei L, Nakajima S, Hsieh CL, Kanno S, Masutani M, Levine AS, Yasui A, Lan L.

J Cell Sci. 2013 Oct 1;126(Pt 19):4414-23. doi: 10.1242/jcs.128272. Epub 2013 Jul 18.


Curcumin suppresses multiple DNA damage response pathways and has potency as a sensitizer to PARP inhibitor.

Ogiwara H, Ui A, Shiotani B, Zou L, Yasui A, Kohno T.

Carcinogenesis. 2013 Nov;34(11):2486-97. doi: 10.1093/carcin/bgt240. Epub 2013 Jul 3.


Direct k-space mapping of the electronic structure in an oxide-oxide interface.

Berner G, Sing M, Fujiwara H, Yasui A, Saitoh Y, Yamasaki A, Nishitani Y, Sekiyama A, Pavlenko N, Kopp T, Richter C, Mannhart J, Suga S, Claessen R.

Phys Rev Lett. 2013 Jun 14;110(24):247601. Epub 2013 Jun 12.


A transfection reporter for the prevention of false-negative results in molecular beacon experiments.

Toga T, Kuraoka I, Yasui A, Iwai S.

Anal Biochem. 2013 Sep 1;440(1):9-11. doi: 10.1016/j.ab.2013.04.027. Epub 2013 May 17.


Alternative excision repair pathways.

Yasui A.

Cold Spring Harb Perspect Biol. 2013 Jun 1;5(6). pii: a012617. doi: 10.1101/cshperspect.a012617. Review.


Possible involvement of LKB1-AMPK signaling in non-homologous end joining.

Ui A, Ogiwara H, Nakajima S, Kanno S, Watanabe R, Harata M, Okayama H, Harris CC, Yokota J, Yasui A, Kohno T.

Oncogene. 2014 Mar 27;33(13):1640-8. doi: 10.1038/onc.2013.125. Epub 2013 Apr 15.


The role of hnRPUL1 involved in DNA damage response is related to PARP1.

Hong Z, Jiang J, Ma J, Dai S, Xu T, Li H, Yasui A.

PLoS One. 2013;8(4):e60208. doi: 10.1371/journal.pone.0060208. Epub 2013 Apr 5.


Improvement of the lipophilic-oxygen radical absorbance capacity (L-ORAC) method and single-laboratory validation.

Watanabe J, Oki T, Takebayashi J, Yamasaki K, Takano-Ishikawa Y, Hino A, Yasui A.

Biosci Biotechnol Biochem. 2013;77(4):857-9. Epub 2013 Apr 7.


Nucleoporin Nup188 is required for chromosome alignment in mitosis.

Itoh G, Sugino S, Ikeda M, Mizuguchi M, Kanno S, Amin MA, Iemura K, Yasui A, Hirota T, Tanaka K.

Cancer Sci. 2013 Jul;104(7):871-9. doi: 10.1111/cas.12159. Epub 2013 May 2.


Polycomb group protein PHF1 regulates p53-dependent cell growth arrest and apoptosis.

Yang Y, Wang C, Zhang P, Gao K, Wang D, Yu H, Zhang T, Jiang S, Hexige S, Hong Z, Yasui A, Liu JO, Huang H, Yu L.

J Biol Chem. 2013 Jan 4;288(1):529-39. doi: 10.1074/jbc.M111.338996. Epub 2012 Nov 13.


Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.

Musselman CA, Avvakumov N, Watanabe R, Abraham CG, Lalonde ME, Hong Z, Allen C, Roy S, Nuñez JK, Nickoloff J, Kulesza CA, Yasui A, Côté J, Kutateladze TG.

Nat Struct Mol Biol. 2012 Dec;19(12):1266-72. doi: 10.1038/nsmb.2435. Epub 2012 Nov 11.


Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair.

Zhang X, Horibata K, Saijo M, Ishigami C, Ukai A, Kanno S, Tahara H, Neilan EG, Honma M, Nohmi T, Yasui A, Tanaka K.

Nat Genet. 2012 May;44(5):593-7. doi: 10.1038/ng.2228.


WRNIP1 accumulates at laser light irradiated sites rapidly via its ubiquitin-binding zinc finger domain and independently from its ATPase domain.

Nomura H, Yoshimura A, Edo T, Kanno S, Tada S, Seki M, Yasui A, Enomoto T.

Biochem Biophys Res Commun. 2012 Jan 27;417(4):1145-50. doi: 10.1016/j.bbrc.2011.12.080. Epub 2011 Dec 22.


Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system.

Li S, Kanno S, Watanabe R, Ogiwara H, Kohno T, Watanabe G, Yasui A, Lieber MR.

J Biol Chem. 2011 Oct 21;286(42):36368-77. doi: 10.1074/jbc.M111.287797. Epub 2011 Sep 1.

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