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Items: 24


Properties of single-channel and whole cell Cl- currents in guinea pig detrusor smooth muscle cells.

Yarotskyy V, Malysz J, Petkov GV.

Am J Physiol Cell Physiol. 2019 May 1;316(5):C698-C710. doi: 10.1152/ajpcell.00327.2018. Epub 2018 Dec 19.


Congenital myopathy results from misregulation of a muscle Ca2+ channel by mutant Stac3.

Linsley JW, Hsu IU, Groom L, Yarotskyy V, Lavorato M, Horstick EJ, Linsley D, Wang W, Franzini-Armstrong C, Dirksen RT, Kuwada JY.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E228-E236. doi: 10.1073/pnas.1619238114. Epub 2016 Dec 21.


Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function.

Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL.

Skelet Muscle. 2015 Jan 29;5:4. doi: 10.1186/s13395-014-0027-1. eCollection 2015.


RGK proteins: fashioning muscle with “Rad” new brakes.

Yarotskyy V, Dirksen RT.

Channels (Austin). 2014;8(4):286-7. No abstract available.


Monovalent cationic channel activity in the inner membrane of nuclei from skeletal muscle fibers.

Yarotskyy V, Dirksen RT.

Biophys J. 2014 Nov 4;107(9):2027-36. doi: 10.1016/j.bpj.2014.09.030.


Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic- and heat-induced sudden death.

Yarotskyy V, Protasi F, Dirksen RT.

PLoS One. 2013 Oct 15;8(10):e77633. doi: 10.1371/journal.pone.0077633. eCollection 2013.


Temperature and RyR1 regulate the activation rate of store-operated Ca²+ entry current in myotubes.

Yarotskyy V, Dirksen RT.

Biophys J. 2012 Jul 18;103(2):202-11. doi: 10.1016/j.bpj.2012.06.001. Epub 2012 Jul 17.


AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation.

Lanner JT, Georgiou DK, Dagnino-Acosta A, Ainbinder A, Cheng Q, Joshi AD, Chen Z, Yarotskyy V, Oakes JM, Lee CS, Monroe TO, Santillan A, Dong K, Goodyear L, Ismailov II, Rodney GG, Dirksen RT, Hamilton SL.

Nat Med. 2012 Jan 8;18(2):244-51. doi: 10.1038/nm.2598.


Domain III regulates N-type (CaV2.2) calcium channel closing kinetics.

Yarotskyy V, Gao G, Peterson BZ, Elmslie KS.

J Neurophysiol. 2012 Apr;107(7):1942-51. doi: 10.1152/jn.00993.2011. Epub 2011 Dec 28.


Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel.

Tang ZZ, Yarotskyy V, Wei L, Sobczak K, Nakamori M, Eichinger K, Moxley RT, Dirksen RT, Thornton CA.

Hum Mol Genet. 2012 Mar 15;21(6):1312-24. doi: 10.1093/hmg/ddr568. Epub 2011 Dec 2.


Roscovitine inhibits CaV3.1 (T-type) channels by preferentially affecting closed-state inactivation.

Yarotskyy V, Elmslie KS.

J Pharmacol Exp Ther. 2012 Feb;340(2):463-72. doi: 10.1124/jpet.111.187104. Epub 2011 Nov 16.


The large-conductance ion channels in the nuclear envelope of central neurons.

Fedorenko O, Yarotskyy V, Duzhyy D, Marchenko S.

Pflugers Arch. 2010 Nov;460(6):1045-50. doi: 10.1007/s00424-010-0882-5. Epub 2010 Oct 1.


The intravenous anesthetic propofol inhibits human L-type calcium channels by enhancing voltage-dependent inactivation.

Fassl J, High KM, Stephenson ER, Yarotskyy V, Elmslie KS.

J Clin Pharmacol. 2011 May;51(5):719-30. doi: 10.1177/0091270010373098. Epub 2010 Jun 14.


Interference between two modulators of N-type (CaV2.2) calcium channel gating demonstrates that omega-conotoxin GVIA disrupts open state gating.

Yarotskyy V, Elmslie KS.

Biochim Biophys Acta. 2010 Sep;1798(9):1821-8. doi: 10.1016/j.bbamem.2010.05.004. Epub 2010 May 13.


Phospholemman modulates the gating of cardiac L-type calcium channels.

Wang X, Gao G, Guo K, Yarotskyy V, Huang C, Elmslie KS, Peterson BZ.

Biophys J. 2010 Apr 7;98(7):1149-59. doi: 10.1016/j.bpj.2009.11.032.


Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, omega-selenoconotoxin GVIA.

Gowd KH, Yarotskyy V, Elmslie KS, Skalicky JJ, Olivera BM, Bulaj G.

Biochemistry. 2010 Mar 30;49(12):2741-52. doi: 10.1021/bi902137c.


Roscovitine binds to novel L-channel (CaV1.2) sites that separately affect activation and inactivation.

Yarotskyy V, Gao G, Du L, Ganapathi SB, Peterson BZ, Elmslie KS.

J Biol Chem. 2010 Jan 1;285(1):43-53. doi: 10.1074/jbc.M109.076448. Epub 2009 Nov 2.


Open-state occupancy prevents gating charge relaxation of N-type (CaV2.2) calcium channels.

Yarotskyy V, Elmslie KS.

Biophys J. 2009 Nov 4;97(9):2446-55. doi: 10.1016/j.bpj.2009.08.014.


The Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation.

Yarotskyy V, Gao G, Peterson BZ, Elmslie KS.

J Physiol. 2009 Feb 1;587(3):551-65. doi: 10.1113/jphysiol.2008.161737. Epub 2008 Dec 15.


omega-conotoxin GVIA alters gating charge movement of N-type (CaV2.2) calcium channels.

Yarotskyy V, Elmslie KS.

J Neurophysiol. 2009 Jan;101(1):332-40. doi: 10.1152/jn.91064.2008. Epub 2008 Oct 29.


Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders.

Martynyuk AE, Seubert CN, Yarotskyy V, Glushakov AV, Gravenstein N, Sumners C, Dennis DM.

Recent Pat CNS Drug Discov. 2006 Nov;1(3):261-70. Review.


Spontaneously active and InsP3-activated ion channels in cell nuclei from rat cerebellar Purkinje and granule neurones.

Marchenko SM, Yarotskyy VV, Kovalenko TN, Kostyuk PG, Thomas RC.

J Physiol. 2005 Jun 15;565(Pt 3):897-910. Epub 2005 Mar 17.


Differential modulation of glutamatergic transmission by 3,5-dibromo-L-phenylalanine.

Yarotskyy V, Glushakov AV, Sumners C, Gravenstein N, Dennis DM, Seubert CN, Martynyuk AE.

Mol Pharmacol. 2005 May;67(5):1648-54. Epub 2005 Feb 1.


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