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Dynamin and reverse-mode sodium calcium exchanger blockade confers neuroprotection from diffuse axonal injury.

Omelchenko A, Shrirao AB, Bhattiprolu AK, Zahn JD, Schloss RS, Dickson S, Meaney DF, Boustany NN, Yarmush ML, Firestein BL.

Cell Death Dis. 2019 Sep 27;10(10):727. doi: 10.1038/s41419-019-1908-3.


Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages.

Krishnan S, Ding Y, Saeidi N, Choi M, Sridharan GV, Sherr DH, Yarmush ML, Alaniz RC, Jayaraman A, Lee K.

Cell Rep. 2019 Sep 17;28(12):3285. doi: 10.1016/j.celrep.2019.08.080. No abstract available.


Supercooling extends preservation time of human livers.

de Vries RJ, Tessier SN, Banik PD, Nagpal S, Cronin SEJ, Ozer S, Hafiz EOA, van Gulik TM, Yarmush ML, Markmann JF, Toner M, Yeh H, Uygun K.

Nat Biotechnol. 2019 Oct;37(10):1131-1136. doi: 10.1038/s41587-019-0223-y. Epub 2019 Sep 9.


A microfluidic patterned model of non-alcoholic fatty liver disease: applications to disease progression and zonation.

Bulutoglu B, Rey-Bedón C, Kang YBA, Mert S, Yarmush ML, Usta OB.

Lab Chip. 2019 Sep 10;19(18):3022-3031. doi: 10.1039/c9lc00354a.


Repopulation of intrahepatic bile ducts in engineered rat liver grafts.

Chen Y, Devalliere J, Bulutoglu B, Yarmush ML, Uygun BE.

Technology (Singap World Sci). 2019 Mar-Jun;7(1-2):46-55. doi: 10.1142/S2339547819500043. Epub 2019 Jun 28.


A microfluidic 3D hepatocyte chip for hepatotoxicity testing of nanoparticles.

Li L, Gokduman K, Gokaltun A, Yarmush ML, Usta OB.

Nanomedicine (Lond). 2019 Aug;14(16):2209-2226. doi: 10.2217/nnm-2019-0086. Epub 2019 Jun 10.


Simple Surface Modification of Poly(dimethylsiloxane) via Surface Segregating Smart Polymers for Biomicrofluidics.

Gökaltun A, Kang YBA, Yarmush ML, Usta OB, Asatekin A.

Sci Rep. 2019 May 14;9(1):7377. doi: 10.1038/s41598-019-43625-5.


Mouse Model of Pressure Ulcers After Spinal Cord Injury.

Kumar S, Tan Y, Yarmush ML, Dash BC, Hsia HC, Berthiaume F.

J Vis Exp. 2019 Mar 9;(145). doi: 10.3791/58188.


The growing role of precision and personalized medicine for cancer treatment.

Krzyszczyk P, Acevedo A, Davidoff EJ, Timmins LM, Marrero-Berrios I, Patel M, White C, Lowe C, Sherba JJ, Hartmanshenn C, O'Neill KM, Balter ML, Fritz ZR, Androulakis IP, Schloss RS, Yarmush ML.

Technology (Singap World Sci). 2018 Sep-Dec;6(3-4):79-100. doi: 10.1142/S2339547818300020. Epub 2019 Jan 11.


Oxygenated UW Solution Decreases ATP Decay and Improves Survival After Transplantation of DCD Liver Grafts.

Martins PN, Berendsen TA, Yeh H, Bruinsma BG, Izamis ML, Op den Dries S, Gillooly AR, Porte R, Yarmush ML, Uygun K, Markmann JF.

Transplantation. 2019 Feb;103(2):363-370. doi: 10.1097/TP.0000000000002530.


Rejuvenation of aged rat skin with pulsed electric fields.

Li X, Saeidi N, Villiger M, Albadawi H, Jones JD, Quinn KP, Austin WG Jr, Golberg A, Yarmush ML.

J Tissue Eng Regen Med. 2018 Dec;12(12):2309-2318. doi: 10.1002/term.2763. Epub 2018 Nov 22.


Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity.

Luther J, Gala MK, Borren N, Masia R, Goodman RP, Moeller IH, DiGiacomo E, Ehrlich A, Warren A, Yarmush ML, Ananthakrishnan A, Corey K, Kaplan LM, Bhatia S, Chung RT, Patel SJ.

Hepatol Commun. 2018 Jul 16;2(7):786-797. doi: 10.1002/hep4.1179. eCollection 2018 Jul.


Long-term deep-supercooling of large-volume water and red cell suspensions via surface sealing with immiscible liquids.

Huang H, Yarmush ML, Usta OB.

Nat Commun. 2018 Aug 10;9(1):3201. doi: 10.1038/s41467-018-05636-0.


Improving functional re-endothelialization of acellular liver scaffold using REDV cell-binding domain.

Devalliere J, Chen Y, Dooley K, Yarmush ML, Uygun BE.

Acta Biomater. 2018 Sep 15;78:151-164. doi: 10.1016/j.actbio.2018.07.046. Epub 2018 Jul 31.


Automated end-to-end blood testing at the point-of-care: Integration of robotic phlebotomy with downstream sample processing.

Balter ML, Leipheimer JM, Chen AI, Shrirao A, Maguire TJ, Yarmush ML.

Technology (Singap World Sci). 2018 Jun;6(2):59-66. doi: 10.1142/S2339547818500048.


Dose-, treatment- and time-dependent toxicity of superparamagnetic iron oxide nanoparticles on primary rat hepatocytes.

Gokduman K, Bestepe F, Li L, Yarmush ML, Usta OB.

Nanomedicine (Lond). 2018 Jun;13(11):1267-1284. doi: 10.2217/nnm-2017-0387.


Metabolic Patterning on a Chip: Towards in vitro Liver Zonation of Primary Rat and Human Hepatocytes.

Kang YBA, Eo J, Mert S, Yarmush ML, Usta OB.

Sci Rep. 2018 Jun 12;8(1):8951. doi: 10.1038/s41598-018-27179-6.


Multi-omic network-based interrogation of rat liver metabolism following gastric bypass surgery featuring SWATH proteomics.

Sridharan GV, D'Alessandro M, Bale SS, Bhagat V, Gagnon H, Asara JM, Uygun K, Yarmush ML, Saeidi N.

Technology (Singap World Sci). 2017 Sep;5(3):139-184. doi: 10.1142/S233954781750008X. Epub 2017 Sep 26.


Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages.

Krishnan S, Ding Y, Saedi N, Choi M, Sridharan GV, Sherr DH, Yarmush ML, Alaniz RC, Jayaraman A, Lee K.

Cell Rep. 2018 Apr 24;23(4):1099-1111. doi: 10.1016/j.celrep.2018.03.109. Erratum in: Cell Rep. 2019 Sep 17;28(12):3285.


Microfluidic flow cytometry: The role of microfabrication methodologies, performance and functional specification.

Shrirao AB, Fritz Z, Novik EM, Yarmush GM, Schloss RS, Zahn JD, Yarmush ML.

Technology (Singap World Sci). 2018 Mar;6(1):1-23. doi: 10.1142/S2339547818300019. Epub 2018 Mar 16.


Prostaglandin E2 Produced by Alginate-Encapsulated Mesenchymal Stromal Cells Modulates the Astrocyte Inflammatory Response.

Stucky EC, Erndt-Marino J, Schloss RS, Yarmush ML, Shreiber DI.

Nano Life. 2017 Jun;7(2). pii: 1750005. doi: 10.1142/s1793984417500052.


Microfluidic platforms for the study of neuronal injury in vitro.

Shrirao AB, Kung FH, Omelchenko A, Schloss RS, Boustany NN, Zahn JD, Yarmush ML, Firestein BL.

Biotechnol Bioeng. 2018 Apr;115(4):815-830. doi: 10.1002/bit.26519. Epub 2018 Feb 21. Review.


Design and Evaluation of a Robotic Device for Automated Tail Vein Cannulations in Rodent Models.

Fromholtz A, Balter ML, Chen AI, Leipheimer JM, Shrirao A, Maguire TJ, Yarmush ML.

J Med Device. 2017 Dec;11(4):0410081-410087. doi: 10.1115/1.4038011. Epub 2017 Oct 16.


Decellularized human liver extracellular matrix (hDLM)-mediated hepatic differentiation of human induced pluripotent stem cells (hIPSCs).

Jaramillo M, Yeh H, Yarmush ML, Uygun BE.

J Tissue Eng Regen Med. 2018 Apr;12(4):e1962-e1973. doi: 10.1002/term.2627. Epub 2018 Jan 21.


Impact of Complete Spinal Cord Injury on Healing of Skin Ulcers in Mouse Models.

Kumar S, Yarmush ML, Dash BC, Hsia HC, Berthiaume F.

J Neurotrauma. 2018 Mar 15;35(6):815-824. doi: 10.1089/neu.2017.5405. Epub 2018 Jan 11.


Metabolomic Modularity Analysis (MMA) to Quantify Human Liver Perfusion Dynamics.

Sridharan GV, Bruinsma BG, Bale SS, Swaminathan A, Saeidi N, Yarmush ML, Uygun K.

Metabolites. 2017 Nov 13;7(4). pii: E58. doi: 10.3390/metabo7040058.


Live cell imaging of cytosolic NADH/NAD+ ratio in hepatocytes and liver slices.

Masia R, McCarty WJ, Lahmann C, Luther J, Chung RT, Yarmush ML, Yellen G.

Am J Physiol Gastrointest Liver Physiol. 2018 Jan 1;314(1):G97-G108. doi: 10.1152/ajpgi.00093.2017. Epub 2017 Oct 12.


Recent advances in nonbiofouling PDMS surface modification strategies applicable to microfluidic technology.

Gokaltun A, Yarmush ML, Asatekin A, Usta OB.

Technology (Singap World Sci). 2017 Mar;5(1):1-12. doi: 10.1142/S2339547817300013. Epub 2017 Feb 7.


Co-delivery of a growth factor and a tissue-protective molecule using elastin biopolymers accelerates wound healing in diabetic mice.

Devalliere J, Dooley K, Hu Y, Kelangi SS, Uygun BE, Yarmush ML.

Biomaterials. 2017 Oct;141:149-160. doi: 10.1016/j.biomaterials.2017.06.043. Epub 2017 Jun 30.


Regulation of Energy Homeostasis After Gastric Bypass Surgery.

Yarmush ML, D'Alessandro M, Saeidi N.

Annu Rev Biomed Eng. 2017 Jun 21;19:459-484. doi: 10.1146/annurev-bioeng-071813-105140. Review.


Generation and manipulation of hydrogel microcapsules by droplet-based microfluidics for mammalian cell culture.

Huang H, Yu Y, Hu Y, He X, Berk Usta O, Yarmush ML.

Lab Chip. 2017 May 31;17(11):1913-1932. doi: 10.1039/c7lc00262a. Review.


Differential Leukocyte Counting via Fluorescent Detection and Image Processing on a Centrifugal Microfluidic Platform.

Balter ML, Chen AI, Colinco CA, Gorshkov A, Bixon B, Martin V, Fromholtz A, Maguire TJ, Yarmush ML.

Anal Methods. 2016 Dec 21;8(47):8272-8279. doi: 10.1039/C6AY02614A. Epub 2016 Oct 28.


System Design and Development of a Robotic Device for Automated Venipuncture and Diagnostic Blood Cell Analysis.

Balter ML, Chen AI, Fromholtz A, Gorshkov A, Maguire TJ, Yarmush ML.

Rep U S. 2016 Oct;2016:514-520. doi: 10.1109/IROS.2016.7759102. Epub 2016 Dec 1.


CFD assessment of the effect of convective mass transport on the intracellular clearance of intracellular triglycerides in macrosteatotic hepatocytes.

Yarmush G, Santos L, Yarmush J, Koundinyan S, Saleem M, Nativ NI, Yarmush ML, Berthiaume F, Maguire TJ, Guaghan C.

Biomech Model Mechanobiol. 2017 Aug;16(4):1095-1102. doi: 10.1007/s10237-017-0882-x. Epub 2017 Feb 20.


Stromal Cell-Derived Growth Factor-1 Alpha-Elastin Like Peptide Fusion Protein Promotes Cell Migration and Revascularization of Experimental Wounds in Diabetic Mice.

Yeboah A, Maguire T, Schloss R, Berthiaume F, Yarmush ML.

Adv Wound Care (New Rochelle). 2017 Jan 1;6(1):10-22. doi: 10.1089/wound.2016.0694.


Adaptive Kinematic Control of a Robotic Venipuncture Device Based on Stereo Vision, Ultrasound, and Force Guidance.

Balter ML, Chen AI, Maguire TJ, Yarmush ML.

IEEE Trans Ind Electron. 2017 Feb;64(2):1626-1635. doi: 10.1109/TIE.2016.2557306. Epub 2016 Apr 21.


3D Near Infrared and Ultrasound Imaging of Peripheral Blood Vessels for Real-Time Localization and Needle Guidance.

Chen AI, Balter ML, Maguire TJ, Yarmush ML.

Med Image Comput Comput Assist Interv. 2016 Oct;9902:388-396. Epub 2016 Oct 2.


Skin regeneration with all accessory organs following ablation with irreversible electroporation.

Golberg A, Villiger M, Felix Broelsch G, Quinn KP, Albadawi H, Khan S, Watkins MT, Georgakoudi I, Austen WG Jr, Bei M, Bouma BE, Mihm MC Jr, Yarmush ML.

J Tissue Eng Regen Med. 2018 Jan;12(1):98-113. doi: 10.1002/term.2374. Epub 2017 May 23.


Discarded Livers Find a New Life: Engineered Liver Grafts Using Hepatocytes Recovered From Marginal Livers.

Uygun BE, Izamis ML, Jaramillo M, Chen Y, Price G, Ozer S, Yarmush ML.

Artif Organs. 2017 Jun;41(6):579-585. doi: 10.1111/aor.12781. Epub 2016 Nov 8.


Preventing Scars after Injury with Partial Irreversible Electroporation.

Golberg A, Villiger M, Khan S, Quinn KP, Lo WCY, Bouma BE, Mihm MC Jr, Austen WG Jr, Yarmush ML.

J Invest Dermatol. 2016 Nov;136(11):2297-2304. doi: 10.1016/j.jid.2016.06.620. Epub 2016 Jul 5.


Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types.

Salloum S, Holmes JA, Jindal R, Bale SS, Brisac C, Alatrakchi N, Lidofsky A, Kruger AJ, Fusco DN, Luther J, Schaefer EA, Lin W, Yarmush ML, Chung RT.

Hepatology. 2016 Dec;64(6):1951-1968. doi: 10.1002/hep.28766. Epub 2016 Oct 5.


Multilayered tissue mimicking skin and vessel phantoms with tunable mechanical, optical, and acoustic properties.

Chen AI, Balter ML, Chen MI, Gross D, Alam SK, Maguire TJ, Yarmush ML.

Med Phys. 2016 Jun;43(6):3117-3131. doi: 10.1118/1.4951729.


Single-step electrical field strength screening to determine electroporation induced transmembrane transport parameters.

Blumrosen G, Abazari A, Golberg A, Yarmush ML, Toner M.

Biochim Biophys Acta. 2016 Sep;1858(9):2041-2049. doi: 10.1016/j.bbamem.2016.05.022. Epub 2016 Jun 3.


A Microfabricated Platform for Generating Physiologically-Relevant Hepatocyte Zonation.

McCarty WJ, Usta OB, Yarmush ML.

Sci Rep. 2016 May 31;6:26868. doi: 10.1038/srep26868.


Functionalized Biopolymer Particles Enhance Performance of a Tissue-Protective Peptide under Proteolytic and Thermal Stress.

Dooley K, Devalliere J, Uygun BE, Yarmush ML.

Biomacromolecules. 2016 Jun 13;17(6):2073-9. doi: 10.1021/acs.biomac.6b00280. Epub 2016 May 31.


Nondestructive Methods for Monitoring Cell Removal During Rat Liver Decellularization.

Geerts S, Ozer S, Jaramillo M, Yarmush ML, Uygun BE.

Tissue Eng Part C Methods. 2016 Jul;22(7):671-8. doi: 10.1089/ten.TEC.2015.0571. Epub 2016 Jun 13.


Isolation and co-culture of rat parenchymal and non-parenchymal liver cells to evaluate cellular interactions and response.

Bale SS, Geerts S, Jindal R, Yarmush ML.

Sci Rep. 2016 May 4;6:25329. doi: 10.1038/srep25329.


Elastin-like polypeptides: A strategic fusion partner for biologics.

Yeboah A, Cohen RI, Rabolli C, Yarmush ML, Berthiaume F.

Biotechnol Bioeng. 2016 Aug;113(8):1617-27. doi: 10.1002/bit.25998. Epub 2016 Jun 3. Review.


Nanolayered siRNA delivery platforms for local silencing of CTGF reduce cutaneous scar contraction in third-degree burns.

Castleberry SA, Golberg A, Sharkh MA, Khan S, Almquist BD, Austen WG Jr, Yarmush ML, Hammond PT.

Biomaterials. 2016 Jul;95:22-34. doi: 10.1016/j.biomaterials.2016.04.007. Epub 2016 Apr 14.


The development and characterization of SDF1α-elastin-like-peptide nanoparticles for wound healing.

Yeboah A, Cohen RI, Faulknor R, Schloss R, Yarmush ML, Berthiaume F.

J Control Release. 2016 Jun 28;232:238-47. doi: 10.1016/j.jconrel.2016.04.020. Epub 2016 Apr 16.

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