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Items: 1 to 50 of 286

1.

Induction of Kaposi Sarcoma Associated Herpesvirus-encoded Thymidine Kinase (ORF21) by X-Box Binding Protein-1.

Wang V, Davis DA, Deleage C, Brands C, Choi HS, Haque M, Yarchoan R.

J Virol. 2019 Dec 4. pii: JVI.01555-19. doi: 10.1128/JVI.01555-19. [Epub ahead of print]

PMID:
31801863
2.

No evidence of ongoing HIV replication or compartmentalization in tissues during combination antiretroviral therapy: Implications for HIV eradication.

Bozzi G, Simonetti FR, Watters SA, Anderson EM, Gouzoulis M, Kearney MF, Rote P, Lange C, Shao W, Gorelick R, Fullmer B, Kumar S, Wank S, Hewitt S, Kleiner DE, Hattori J, Bale MJ, Hill S, Bell J, Rehm C, Grossman Z, Yarchoan R, Uldrick T, Maldarelli F.

Sci Adv. 2019 Sep 25;5(9):eaav2045. doi: 10.1126/sciadv.aav2045. eCollection 2019 Sep.

3.

Assessment of the Safety of Pembrolizumab in Patients With HIV and Advanced Cancer-A Phase 1 Study.

Uldrick TS, Gonçalves PH, Abdul-Hay M, Claeys AJ, Emu B, Ernstoff MS, Fling SP, Fong L, Kaiser JC, Lacroix AM, Lee SY, Lundgren LM, Lurain K, Parsons CH, Peeramsetti S, Ramaswami R, Sharon E, Sznol M, Wang CJ, Yarchoan R, Cheever MA; Cancer Immunotherapy Trials Network (CITN)-12 Study Team.

JAMA Oncol. 2019 Jun 2. doi: 10.1001/jamaoncol.2019.2244. [Epub ahead of print]

PMID:
31154457
4.

The Changing Face of HIV-Associated Malignancies: Advances, Opportunities, and Future Directions.

Lurain K, Yarchoan R, Ramaswami R.

Am Soc Clin Oncol Educ Book. 2019 Jan;39:36-40. doi: 10.1200/EDBK_100017. Epub 2019 May 17. Review.

5.

A Pilot Study of Liposomal Doxorubicin Combined with Bevacizumab followed by Bevacizumab Monotherapy in Patients with Advanced Kaposi Sarcoma.

Ramaswami R, Uldrick TS, Polizzotto MN, Wyvill KM, Goncalves P, Widell A, Lurain K, Steinberg SM, Figg WD, Tosato G, Whitby D, Yarchoan R.

Clin Cancer Res. 2019 Jul 15;25(14):4238-4247. doi: 10.1158/1078-0432.CCR-18-3528. Epub 2019 Apr 12.

PMID:
30979736
6.

Viral, immunologic, and clinical features of primary effusion lymphoma.

Lurain K, Polizzotto MN, Aleman K, Bhutani M, Wyvill KM, Gonçalves PH, Ramaswami R, Marshall VA, Miley W, Steinberg SM, Little RF, Wilson W, Filie AC, Pittaluga S, Jaffe ES, Whitby D, Yarchoan R, Uldrick TS.

Blood. 2019 Apr 18;133(16):1753-1761. doi: 10.1182/blood-2019-01-893339. Epub 2019 Feb 19.

7.

Pomalidomide increases immune surface marker expression and immune recognition of oncovirus-infected cells.

Davis DA, Shrestha P, Aisabor AI, Stream A, Galli V, Pise-Masison CA, Tagawa T, Ziegelbauer JM, Franchini G, Yarchoan R.

Oncoimmunology. 2018 Dec 5;8(2):e1546544. doi: 10.1080/2162402X.2018.1546544. eCollection 2019.

8.

Emergence of Kaposi's Sarcoma Herpesvirus-Associated Complications Following Corticosteroid Use in TB-IRIS.

Manion M, Uldrick T, Polizzotto MN, Sheikh V, Roby G, Lurain K, Metzger D, Mican JM, Pau A, Lisco A, Laidlaw E, Hammoud DA, Whitby D, Yarchoan R, Sereti I.

Open Forum Infect Dis. 2018 Oct 12;5(10):ofy217. doi: 10.1093/ofid/ofy217. eCollection 2018 Oct.

9.

Metagenomic Discovery of 83 New Human Papillomavirus Types in Patients with Immunodeficiency.

Pastrana DV, Peretti A, Welch NL, Borgogna C, Olivero C, Badolato R, Notarangelo LD, Gariglio M, FitzGerald PC, McIntosh CE, Reeves J, Starrett GJ, Bliskovsky V, Velez D, Brownell I, Yarchoan R, Wyvill KM, Uldrick TS, Maldarelli F, Lisco A, Sereti I, Gonzalez CM, Androphy EJ, McBride AA, Van Doorslaer K, Garcia F, Dvoretzky I, Liu JS, Han J, Murphy PM, McDermott DH, Buck CB.

mSphere. 2018 Dec 12;3(6). pii: e00645-18. doi: 10.1128/mSphereDirect.00645-18.

10.

Polymorphisms in KSHV-encoded microRNA sequences affect levels of mature viral microRNA in Kaposi Sarcoma lesions.

Marshall VA, Labo N, Sztuba-Solinska J, Cornejo Castro EM, Aleman K, Wyvill KM, McNamara L, Le Grice SFJ, Yarchoan R, Uldrick TS, MacPhail P, Polizzotto MN, Whitby D.

Oncotarget. 2018 Nov 9;9(88):35856-35869. doi: 10.18632/oncotarget.26321. eCollection 2018 Nov 9.

11.

Discovery of Kaposi's sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA.

Tagawa T, Gao S, Koparde VN, Gonzalez M, Spouge JL, Serquiña AP, Lurain K, Ramaswami R, Uldrick TS, Yarchoan R, Ziegelbauer JM.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12805-12810. doi: 10.1073/pnas.1816183115. Epub 2018 Nov 19.

12.

HIV-Associated Cancers and Related Diseases.

Yarchoan R, Uldrick TS.

N Engl J Med. 2018 May 31;378(22):2145. doi: 10.1056/NEJMc1804812. No abstract available.

PMID:
29847760
13.

Relationship Between Anemia, Malaria Coinfection, and Kaposi Sarcoma-Associated Herpesvirus Seropositivity in a Population-Based Study in Rural Uganda.

Nalwoga A, Cose S, Nash S, Miley W, Asiki G, Kusemererwa S, Yarchoan R, Labo N, Whitby D, Newton R.

J Infect Dis. 2018 Aug 24;218(7):1061-1065. doi: 10.1093/infdis/jiy274.

14.

HIV-Associated Cancers and Related Diseases.

Yarchoan R, Uldrick TS.

N Engl J Med. 2018 Mar 15;378(11):1029-1041. doi: 10.1056/NEJMra1615896. Review. No abstract available.

15.

T-cell responses to KSHV infection: a systematic approach.

Roshan R, Labo N, Trivett M, Miley W, Marshall V, Coren L, Cornejo Castro EM, Perez H, Holdridge B, Davis E, Matus-Nicodemos R, Ayala VI, Sowder R 2nd, Wyvill KM, Aleman K, Fennessey C, Lifson J, Polizzotto MN, Douek D, Keele B, Uldrick TS, Yarchoan R, Ohlen C, Ott D, Whitby D.

Oncotarget. 2017 Nov 25;8(65):109402-109416. doi: 10.18632/oncotarget.22683. eCollection 2017 Dec 12.

16.

Treatment of Kaposi Sarcoma Herpesvirus-Associated Multicentric Castleman Disease.

Lurain K, Yarchoan R, Uldrick TS.

Hematol Oncol Clin North Am. 2018 Feb;32(1):75-88. doi: 10.1016/j.hoc.2017.09.007. Review.

17.

A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency.

Aoki M, Hayashi H, Rao KV, Das D, Higashi-Kuwata N, Bulut H, Aoki-Ogata H, Takamatsu Y, Yedidi RS, Davis DA, Hattori SI, Nishida N, Hasegawa K, Takamune N, Nyalapatla PR, Osswald HL, Jono H, Saito H, Yarchoan R, Misumi S, Ghosh AK, Mitsuya H.

Elife. 2017 Oct 17;6. pii: e28020. doi: 10.7554/eLife.28020.

18.

Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma.

Shrestha P, Davis DA, Veeranna RP, Carey RF, Viollet C, Yarchoan R.

PLoS Pathog. 2017 Sep 18;13(9):e1006628. doi: 10.1371/journal.ppat.1006628. eCollection 2017 Sep.

19.

Restoration of immune surface molecules in Kaposi sarcoma-associated herpes virus infected cells by lenalidomide and pomalidomide.

Davis DA, Mishra S, Anagho HA, Aisabor AI, Shrestha P, Wang V, Takamatsu Y, Maeda K, Mitsuya H, Zeldis JB, Yarchoan R.

Oncotarget. 2017 May 17;8(31):50342-50358. doi: 10.18632/oncotarget.17960. eCollection 2017 Aug 1.

20.

Corrigendum: Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: multicentric Castleman disease (KSHV-MCD) and the KSHV inflammatory cytokine syndrome.

Polizzotto MN, Uldrick TS, Hu D, Yarchoan R.

Front Microbiol. 2017 Aug 21;8:1572. doi: 10.3389/fmicb.2017.01572. eCollection 2017.

21.

Identification of functional hypoxia inducible factor response elements in the human lysyl oxidase gene promoter.

Wang V, Davis DA, Yarchoan R.

Biochem Biophys Res Commun. 2017 Aug 19;490(2):480-485. doi: 10.1016/j.bbrc.2017.06.066. Epub 2017 Jun 15.

22.

HIV-associated Kaposi sarcoma and related diseases.

Gonçalves PH, Uldrick TS, Yarchoan R.

AIDS. 2017 Sep 10;31(14):1903-1916. doi: 10.1097/QAD.0000000000001567. Review.

23.

Evidence for a Mesothelial Origin of Body Cavity Effusion Lymphomas.

Sanchez-Martin D, Uldrick TS, Kwak H, Ohnuki H, Polizzotto MN, Annunziata CM, Raffeld M, Wyvill KM, Aleman K, Wang V, Marshall VA, Whitby D, Yarchoan R, Tosato G.

J Natl Cancer Inst. 2017 Sep 1;109(9). doi: 10.1093/jnci/djx016.

24.

A Phase Ib Study of Sorafenib (BAY 43-9006) in Patients with Kaposi Sarcoma.

Uldrick TS, Gonçalves PH, Wyvill KM, Peer CJ, Bernstein W, Aleman K, Polizzotto MN, Venzon D, Steinberg SM, Marshall V, Whitby D, Little RF, Wright JJ, Rudek MA, Figg WD, Yarchoan R.

Oncologist. 2017 May;22(5):505-e49. doi: 10.1634/theoncologist.2016-0486. Epub 2017 Mar 24.

25.

Flow virometric sorting and analysis of HIV quasispecies from plasma.

Musich T, Jones JC, Keele BF, Jenkins LMM, Demberg T, Uldrick TS, Yarchoan R, Robert-Guroff M.

JCI Insight. 2017 Feb 23;2(4):e90626. doi: 10.1172/jci.insight.90626.

26.

Clinical and pathological characteristics of HIV- and HHV-8-negative Castleman disease.

Yu L, Tu M, Cortes J, Xu-Monette ZY, Miranda RN, Zhang J, Orlowski RZ, Neelapu S, Boddu PC, Akosile MA, Uldrick TS, Yarchoan R, Medeiros LJ, Li Y, Fajgenbaum DC, Young KH.

Blood. 2017 Mar 23;129(12):1658-1668. doi: 10.1182/blood-2016-11-748855. Epub 2017 Jan 18.

27.

RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature.

Viollet C, Davis DA, Tekeste SS, Reczko M, Ziegelbauer JM, Pezzella F, Ragoussis J, Yarchoan R.

PLoS Pathog. 2017 Jan 3;13(1):e1006143. doi: 10.1371/journal.ppat.1006143. eCollection 2017 Jan.

28.

Pomalidomide for Symptomatic Kaposi's Sarcoma in People With and Without HIV Infection: A Phase I/II Study.

Polizzotto MN, Uldrick TS, Wyvill KM, Aleman K, Peer CJ, Bevans M, Sereti I, Maldarelli F, Whitby D, Marshall V, Goncalves PH, Khetani V, Figg WD, Steinberg SM, Zeldis JB, Yarchoan R.

J Clin Oncol. 2016 Dec;34(34):4125-4131. Epub 2016 Oct 31. Erratum in: J Clin Oncol. 2018 Jul 1;36(19):2008.

29.

Kaposi sarcoma herpesvirus-associated cancers and related diseases.

Goncalves PH, Ziegelbauer J, Uldrick TS, Yarchoan R.

Curr Opin HIV AIDS. 2017 Jan;12(1):47-56. Review.

30.

Cancer prevention in HIV-infected populations.

Goncalves PH, Montezuma-Rusca JM, Yarchoan R, Uldrick TS.

Semin Oncol. 2016 Feb;43(1):173-188. doi: 10.1053/j.seminoncol.2015.09.011. Epub 2015 Sep 8. Review.

31.

Clinical Features and Outcomes of Patients With Symptomatic Kaposi Sarcoma Herpesvirus (KSHV)-associated Inflammation: Prospective Characterization of KSHV Inflammatory Cytokine Syndrome (KICS).

Polizzotto MN, Uldrick TS, Wyvill KM, Aleman K, Marshall V, Wang V, Whitby D, Pittaluga S, Jaffe ES, Millo C, Tosato G, Little RF, Steinberg SM, Sereti I, Yarchoan R.

Clin Infect Dis. 2016 Mar 15;62(6):730-738. doi: 10.1093/cid/civ996. Epub 2015 Dec 12. Erratum in: Clin Infect Dis. 2018 Mar 5;66(6):985.

32.

Induction of Kaposi's Sarcoma-Associated Herpesvirus-Encoded Viral Interleukin-6 by X-Box Binding Protein 1.

Hu D, Wang V, Yang M, Abdullah S, Davis DA, Uldrick TS, Polizzotto MN, Veeranna RP, Pittaluga S, Tosato G, Yarchoan R.

J Virol. 2015 Oct 21;90(1):368-78. doi: 10.1128/JVI.01192-15. Print 2016 Jan 1.

33.

Identification of Caspase Cleavage Sites in KSHV Latency-Associated Nuclear Antigen and Their Effects on Caspase-Related Host Defense Responses.

Davis DA, Naiman NE, Wang V, Shrestha P, Haque M, Hu D, Anagho HA, Carey RF, Davidoff KS, Yarchoan R.

PLoS Pathog. 2015 Jul 28;11(7):e1005064. doi: 10.1371/journal.ppat.1005064. eCollection 2015 Jul.

34.

Next-Generation Sequencing Analysis Reveals Differential Expression Profiles of MiRNA-mRNA Target Pairs in KSHV-Infected Cells.

Viollet C, Davis DA, Reczko M, Ziegelbauer JM, Pezzella F, Ragoussis J, Yarchoan R.

PLoS One. 2015 May 5;10(5):e0126439. doi: 10.1371/journal.pone.0126439. eCollection 2015.

35.

Kaposi sarcoma-associated herpesvirus-associated malignancies: epidemiology, pathogenesis, and advances in treatment.

Bhutani M, Polizzotto MN, Uldrick TS, Yarchoan R.

Semin Oncol. 2015 Apr;42(2):223-46. doi: 10.1053/j.seminoncol.2014.12.027. Epub 2014 Dec 31. Review.

36.

18F-fluorodeoxyglucose Positron Emission Tomography in Kaposi Sarcoma Herpesvirus-Associated Multicentric Castleman Disease: Correlation With Activity, Severity, Inflammatory and Virologic Parameters.

Polizzotto MN, Millo C, Uldrick TS, Aleman K, Whatley M, Wyvill KM, O'Mahony D, Marshall V, Whitby D, Maass-Moreno R, Steinberg SM, Little RF, Yarchoan R.

J Infect Dis. 2015 Oct 15;212(8):1250-60. doi: 10.1093/infdis/jiv204. Epub 2015 Mar 31.

37.

Rituximab plus liposomal doxorubicin in HIV-infected patients with KSHV-associated multicentric Castleman disease.

Uldrick TS, Polizzotto MN, Aleman K, Wyvill KM, Marshall V, Whitby D, Wang V, Pittaluga S, O'Mahony D, Steinberg SM, Little RF, Yarchoan R.

Blood. 2014 Dec 4;124(24):3544-52. doi: 10.1182/blood-2014-07-586800. Epub 2014 Oct 20.

38.

Paradoxical central nervous system immune reconstitution syndrome in acquired immunodeficiency syndrome-related primary central nervous system lymphoma.

Kranick SM, Goncalves PH, Stetler-Stevenson M, Aleman K, Polizzotto MN, Little RF, Yarchoan R, Uldrick TS.

Haematologica. 2015 Jan;100(1):e21-4. doi: 10.3324/haematol.2014.114736. Epub 2014 Oct 10. No abstract available.

39.

Heterogeneity and breadth of host antibody response to KSHV infection demonstrated by systematic analysis of the KSHV proteome.

Labo N, Miley W, Marshall V, Gillette W, Esposito D, Bess M, Turano A, Uldrick T, Polizzotto MN, Wyvill KM, Bagni R, Yarchoan R, Whitby D.

PLoS Pathog. 2014 Mar 27;10(3):e1004046. doi: 10.1371/journal.ppat.1004046. eCollection 2014 Mar.

40.

A sensitive and robust HPLC assay with fluorescence detection for the quantification of pomalidomide in human plasma for pharmacokinetic analyses.

Shahbazi S, Peer CJ, Polizzotto MN, Uldrick TS, Roth J, Wyvill KM, Aleman K, Zeldis JB, Yarchoan R, Figg WD.

J Pharm Biomed Anal. 2014 Apr;92:63-8. doi: 10.1016/j.jpba.2014.01.001. Epub 2014 Jan 9.

41.

Evaluation of non-invasive multispectral imaging as a tool for measuring the effect of systemic therapy in Kaposi sarcoma.

Kainerstorfer JM, Polizzotto MN, Uldrick TS, Rahman R, Hassan M, Najafizadeh L, Ardeshirpour Y, Wyvill KM, Aleman K, Smith PD, Yarchoan R, Gandjbakhche AH.

PLoS One. 2013 Dec 27;8(12):e83887. doi: 10.1371/journal.pone.0083887. eCollection 2013.

42.

Case 29-2013: An HIV-positive man with dyspnea and skin lesions.

Polizzotto MN, Uldrick TS, Yarchoan R.

N Engl J Med. 2014 Jan 2;370(1):87-8. doi: 10.1056/NEJMc1313214. No abstract available.

43.

Human and viral interleukin-6 and other cytokines in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.

Polizzotto MN, Uldrick TS, Wang V, Aleman K, Wyvill KM, Marshall V, Pittaluga S, O'Mahony D, Whitby D, Tosato G, Steinberg SM, Little RF, Yarchoan R.

Blood. 2013 Dec 19;122(26):4189-98. doi: 10.1182/blood-2013-08-519959. Epub 2013 Oct 30.

44.

Activation of virus uptake through induction of macropinocytosis with a novel polymerizing peptide.

Daniels SI, Soule EE, Davidoff KS, Bernbaum JG, Hu D, Maeda K, Stahl SJ, Naiman NE, Waheed AA, Freed EO, Wingfield P, Yarchoan R, Davis DA.

FASEB J. 2014 Jan;28(1):106-16. doi: 10.1096/fj.13-238113. Epub 2013 Oct 4.

45.

Bone marrow findings in HIV-positive patients with Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.

Venkataraman G, Uldrick TS, Aleman K, O'Mahony D, Karcher DS, Steinberg SM, Raffeld MA, Marshall V, Whitby D, Little RF, Yarchoan R, Pittaluga S, Maric I.

Am J Clin Pathol. 2013 May;139(5):651-61. doi: 10.1309/AJCPKGF7U8AWQBVG.

PMID:
23596117
46.

Kaposi's sarcoma-associated herpesvirus microRNAs target IRAK1 and MYD88, two components of the toll-like receptor/interleukin-1R signaling cascade, to reduce inflammatory-cytokine expression.

Abend JR, Ramalingam D, Kieffer-Kwon P, Uldrick TS, Yarchoan R, Ziegelbauer JM.

J Virol. 2012 Nov;86(21):11663-74. doi: 10.1128/JVI.01147-12. Epub 2012 Aug 15.

47.

Recent advances in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.

Uldrick TS, Polizzotto MN, Yarchoan R.

Curr Opin Oncol. 2012 Sep;24(5):495-505. doi: 10.1097/CCO.0b013e328355e0f3. Review.

48.

A20/TNFAIP3 inhibits NF-κB activation induced by the Kaposi's sarcoma-associated herpesvirus vFLIP oncoprotein.

Sakakibara S, Espigol-Frigole G, Gasperini P, Uldrick TS, Yarchoan R, Tosato G.

Oncogene. 2013 Mar 7;32(10):1223-32. doi: 10.1038/onc.2012.145. Epub 2012 Apr 23.

49.

Activity of human immunodeficiency virus type 1 protease inhibitors against the initial autocleavage in Gag-Pol polyprotein processing.

Davis DA, Soule EE, Davidoff KS, Daniels SI, Naiman NE, Yarchoan R.

Antimicrob Agents Chemother. 2012 Jul;56(7):3620-8. doi: 10.1128/AAC.00055-12. Epub 2012 Apr 16.

50.

Sequence analysis of Kaposi sarcoma-associated herpesvirus (KSHV) microRNAs in patients with multicentric Castleman disease and KSHV-associated inflammatory cytokine syndrome.

Ray A, Marshall V, Uldrick T, Leighty R, Labo N, Wyvill K, Aleman K, Polizzotto MN, Little RF, Yarchoan R, Whitby D.

J Infect Dis. 2012 Jun;205(11):1665-76. doi: 10.1093/infdis/jis249. Epub 2012 Mar 23.

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