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Items: 1 to 50 of 132

1.

NSD1 mutations by HPV status in head and neck cancer: differences in survival and response to DNA-damaging agents.

Pan C, Izreig S, Yarbrough WG, Issaeva N.

Cancers Head Neck. 2019 Jul 8;4:3. doi: 10.1186/s41199-019-0042-3. eCollection 2019.

PMID:
31321084
2.

HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis.

Pan C, Issaeva N, Yarbrough WG.

Cancers Head Neck. 2018 Dec 29;3:12. doi: 10.1186/s41199-018-0039-3. eCollection 2018. Review.

3.

Extracapsular extension is not a significant prognostic indicator in non-squamous cancers of the major salivary glands.

Cheraghlou S, Yu PK, Otremba MD, Mehra S, Yarbrough WG, Judson BL.

Cancers Head Neck. 2018 Jul 3;3:5. doi: 10.1186/s41199-018-0032-x. eCollection 2018.

4.

Genomic landscape of a metastatic malignant proliferating tricholemmal tumor and its response to PI3K inhibition.

Gallant JN, Sewell A, Almodovar K, Wang Q, Dahlman KB, Abramson RG, Kapp ME, Brown BT, Boyd KL, Gilbert J, Cohen DN, Yarbrough WG, Zhao Z, Lovly CM.

NPJ Precis Oncol. 2019 Feb 15;3:5. doi: 10.1038/s41698-019-0077-2. eCollection 2019.

5.

Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck.

Lee JW, Parameswaran J, Sandoval-Schaefer T, Eoh KJ, Yang DH, Zhu F, Mehra R, Sharma R, Gaffney SG, Perry EB, Townsend JP, Serebriiskii IG, Golemis EA, Issaeva N, Yarbrough WG, Koo JS, Burtness B.

Clin Cancer Res. 2019 Jun 1;25(11):3430-3442. doi: 10.1158/1078-0432.CCR-18-0440. Epub 2019 Feb 12.

6.

APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma.

Cannataro VL, Gaffney SG, Sasaki T, Issaeva N, Grewal NKS, Grandis JR, Yarbrough WG, Burtness B, Anderson KS, Townsend JP.

Oncogene. 2019 May;38(18):3475-3487. doi: 10.1038/s41388-018-0657-6. Epub 2019 Jan 15.

7.

Clinical value of transoral robotic surgery: Nationwide results from the first 5 years of adoption.

Li H, Torabi SJ, Park HS, Yarbrough WG, Mehra S, Choi R, Judson BL.

Laryngoscope. 2019 Aug;129(8):1844-1855. doi: 10.1002/lary.27740. Epub 2018 Dec 21.

PMID:
30575965
8.

Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers.

Cheng H, Yang X, Si H, Saleh AD, Xiao W, Coupar J, Gollin SM, Ferris RL, Issaeva N, Yarbrough WG, Prince ME, Carey TE, Van Waes C, Chen Z.

Cell Rep. 2018 Oct 30;25(5):1332-1345.e5. doi: 10.1016/j.celrep.2018.10.007.

9.

Pretreatment Identification of Head and Neck Cancer Nodal Metastasis and Extranodal Extension Using Deep Learning Neural Networks.

Kann BH, Aneja S, Loganadane GV, Kelly JR, Smith SM, Decker RH, Yu JB, Park HS, Yarbrough WG, Malhotra A, Burtness BA, Husain ZA.

Sci Rep. 2018 Sep 19;8(1):14036. doi: 10.1038/s41598-018-32441-y.

10.

Adjuvant Chemotherapy Is Associated With Improved Survival for Late-Stage Salivary Squamous Cell Carcinoma.

Cheraghlou S, Schettino A, Zogg CK, Otremba MD, Bhatia A, Park HS, Osborn HA, Mehra S, Yarbrough WG, Judson BL.

Laryngoscope. 2019 Apr;129(4):883-889. doi: 10.1002/lary.27444. Epub 2018 Aug 27.

PMID:
30151947
11.

HPV status in unknown primary head and neck cancer: Prognosis and treatment outcomes.

Cheraghlou S, Torabi SJ, Husain ZA, Otremba MD, Osborn HA, Mehra S, Yarbrough WG, Burtness BA, Judson BL.

Laryngoscope. 2019 Mar;129(3):684-691. doi: 10.1002/lary.27475. Epub 2018 Aug 27.

PMID:
30151832
12.

A Clinical Care Pathway to Reduce ICU Usage in Head and Neck Microvascular Reconstruction.

Morse E, Henderson C, Carafeno T, Dibble J, Longley P, Chan E, Judson B, Yarbrough WG, Sasaki C, Mehra S.

Otolaryngol Head Neck Surg. 2019 May;160(5):783-790. doi: 10.1177/0194599818782404. Epub 2018 Jul 31.

PMID:
30060705
13.

Treatment Delays in Primarily Resected Oropharyngeal Squamous Cell Carcinoma: National Benchmarks and Survival Associations.

Morse E, Judson B, Husain Z, Burtness B, Yarbrough WG, Sasaki C, Cheraghlou S, Mehra S.

Otolaryngol Head Neck Surg. 2018 Jul 31:194599818779052. doi: 10.1177/0194599818779052. [Epub ahead of print]

PMID:
30060700
14.

Advances in biomarkers and treatment strategies for HPV-associated head and neck cancer.

Pan C, Yarbrough WG, Issaeva N.

Oncoscience. 2018 Jun 25;5(5-6):140-141. doi: 10.18632/oncoscience.425. eCollection 2018 May. No abstract available.

15.

Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers.

Zhang J, Chen T, Yang X, Cheng H, Späth SS, Clavijo PE, Chen J, Silvin C, Issaeva N, Su X, Yarbrough WG, Annunziata CM, Chen Z, Van Waes C.

Cancer Res. 2018 Aug 15;78(16):4613-4626. doi: 10.1158/0008-5472.CAN-17-0642. Epub 2018 Jun 19.

PMID:
29921694
16.

Association of Human Papillomavirus Status at Head and Neck Carcinoma Subsites With Overall Survival.

Li H, Torabi SJ, Yarbrough WG, Mehra S, Osborn HA, Judson B.

JAMA Otolaryngol Head Neck Surg. 2018 Jun 1;144(6):519-525. doi: 10.1001/jamaoto.2018.0395.

17.

Adjuvant therapy in major salivary gland cancers: Analysis of 8580 patients in the National Cancer Database.

Cheraghlou S, Kuo P, Mehra S, Agogo GO, Bhatia A, Husain ZA, Yarbrough WG, Burtness BA, Judson BL.

Head Neck. 2018 Jul;40(7):1343-1355. doi: 10.1002/hed.24984. Epub 2018 May 13.

PMID:
29756412
18.

Upfront surgery versus definitive chemoradiotherapy in patients with human Papillomavirus-associated oropharyngeal squamous cell cancer.

Kelly JR, Park HS, An Y, Yarbrough WG, Contessa JN, Decker R, Mehra S, Judson BL, Burtness B, Husain Z.

Oral Oncol. 2018 Apr;79:64-70. doi: 10.1016/j.oraloncology.2018.02.017. Epub 2018 Mar 8.

PMID:
29598952
19.

Salvage Surgery after Radiation Failure in T1/T2 Larynx Cancer: Outcomes following Total versus Conservation Surgery.

Cheraghlou S, Kuo P, Mehra S, Yarbrough WG, Judson BL.

Otolaryngol Head Neck Surg. 2018 Mar;158(3):497-504. doi: 10.1177/0194599817742596. Epub 2018 Jan 2.

PMID:
29292665
20.

Treatment deintensification in human papillomavirus-positive oropharynx cancer: Outcomes from the National Cancer Data Base.

Cheraghlou S, Yu PK, Otremba MD, Park HS, Bhatia A, Zogg CK, Mehra S, Yarbrough WG, Judson BL.

Cancer. 2018 Feb 15;124(4):717-726. doi: 10.1002/cncr.31104. Epub 2017 Dec 15.

21.

Response.

Bledsoe TJ, Park HS, Stahl JM, Yarbrough WG, Burtness BA, Decker RH, Husain ZA.

J Natl Cancer Inst. 2018 Apr 1;110(4):433-434. doi: 10.1093/jnci/djx230. No abstract available.

PMID:
29121329
22.

Demethylation Therapy as a Targeted Treatment for Human Papillomavirus-Associated Head and Neck Cancer.

Biktasova A, Hajek M, Sewell A, Gary C, Bellinger G, Deshpande HA, Bhatia A, Burtness B, Judson B, Mehra S, Yarbrough WG, Issaeva N.

Clin Cancer Res. 2017 Dec 1;23(23):7276-7287. doi: 10.1158/1078-0432.CCR-17-1438. Epub 2017 Sep 15.

23.

Clinical and molecular insights into adenoid cystic carcinoma: Neural crest-like stemness as a target.

Yarbrough WG, Panaccione A, Chang MT, Ivanov SV.

Laryngoscope Investig Otolaryngol. 2016 Aug 4;1(4):60-77. doi: 10.1002/lio2.22. eCollection 2016 Aug. Review.

24.

Untreated oral cavity cancer: Long-term survival and factors associated with treatment refusal.

Cheraghlou S, Kuo P, Mehra S, Yarbrough WG, Judson BL.

Laryngoscope. 2018 Mar;128(3):664-669. doi: 10.1002/lary.26809. Epub 2017 Sep 2.

PMID:
28865100
25.

Treatment guidelines and patterns of care in oral cavity squamous cell carcinoma: Primary surgical resection vs. nonsurgical treatment.

Fujiwara RJT, Burtness B, Husain ZA, Judson BL, Bhatia A, Sasaki CT, Yarbrough WG, Mehra S.

Oral Oncol. 2017 Aug;71:129-137. doi: 10.1016/j.oraloncology.2017.06.013. Epub 2017 Jun 23.

PMID:
28688680
26.

Hypofractionated Radiotherapy for Patients with Early-Stage Glottic Cancer: Patterns of Care and Survival.

Bledsoe TJ, Park HS, Stahl JM, Yarbrough WG, Burtness BA, Decker RH, Husain ZA.

J Natl Cancer Inst. 2017 Oct 1;109(10). doi: 10.1093/jnci/djx042.

PMID:
28521361
27.

MYB fusions and CD markers as tools for authentication and purification of cancer stem cells from salivary adenoid cystic carcinoma.

Panaccione A, Zhang Y, Ryan M, Moskaluk CA, Anderson KS, Yarbrough WG, Ivanov SV.

Stem Cell Res. 2017 May;21:160-166. doi: 10.1016/j.scr.2017.05.002. Epub 2017 May 5.

28.

Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner.

Wamsley JJ, Gary C, Biktasova A, Hajek M, Bellinger G, Virk R, Issaeva N, Yarbrough WG.

Oncogenesis. 2017 Apr 10;6(4):e314. doi: 10.1038/oncsis.2017.12.

29.

The risk of level IB nodal involvement in oropharynx cancer: Guidance for submandibular gland sparing irradiation.

Lee NCJ, Kelly JR, Park HS, Yarbrough WG, Burtness BA, Husain ZA.

Pract Radiat Oncol. 2017 Sep - Oct;7(5):e317-e321. doi: 10.1016/j.prro.2017.02.004. Epub 2017 Feb 16.

PMID:
28356201
30.

Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer.

Bauman JE, Duvvuri U, Gooding WE, Rath TJ, Gross ND, Song J, Jimeno A, Yarbrough WG, Johnson FM, Wang L, Chiosea S, Sen M, Kass J, Johnson JT, Ferris RL, Kim S, Hirsch FR, Ellison K, Flaherty JT, Mills GB, Grandis JR.

JCI Insight. 2017 Mar 23;2(6):e90449. doi: 10.1172/jci.insight.90449.

31.

The prognostic value of extranodal extension in human papillomavirus-associated oropharyngeal squamous cell carcinoma.

An Y, Park HS, Kelly JR, Stahl JM, Yarbrough WG, Burtness BA, Contessa JN, Decker RH, Koshy M, Husain ZA.

Cancer. 2017 Jul 15;123(14):2762-2772. doi: 10.1002/cncr.30598. Epub 2017 Mar 21.

32.

TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinoma.

Hajek M, Sewell A, Kaech S, Burtness B, Yarbrough WG, Issaeva N.

Cancer. 2017 May 15;123(10):1778-1790. doi: 10.1002/cncr.30570. Epub 2017 Mar 13.

33.

Chromosomal abnormalities and molecular landscape of metastasizing mucinous salivary adenocarcinoma.

Panaccione A, Zhang Y, Mi Y, Mitani Y, Yan G, Prasad ML, McDonald WH, El-Naggar AK, Yarbrough WG, Ivanov SV.

Oral Oncol. 2017 Mar;66:38-45. doi: 10.1016/j.oraloncology.2016.12.011. Epub 2017 Jan 9.

34.

Treatment delays in oral cavity squamous cell carcinoma and association with survival.

Fujiwara RJ, Judson BL, Yarbrough WG, Husain Z, Mehra S.

Head Neck. 2017 Apr;39(4):639-646. doi: 10.1002/hed.24608. Epub 2017 Feb 25.

PMID:
28236349
35.

Expression Profiling of Clinical Specimens Supports the Existence of Neural Progenitor-Like Stem Cells in Basal Breast Cancers.

Panaccione A, Guo Y, Yarbrough WG, Ivanov SV.

Clin Breast Cancer. 2017 Jul;17(4):298-306.e7. doi: 10.1016/j.clbc.2017.01.007. Epub 2017 Jan 27.

36.

Novel Role of the Mitochondrial Protein Fus1 in Protection from Premature Hearing Loss via Regulation of Oxidative Stress and Nutrient and Energy Sensing Pathways in the Inner Ear.

Tan WJT, Song L, Graham M, Schettino A, Navaratnam D, Yarbrough WG, Santos-Sacchi J, Ivanova AV.

Antioxid Redox Signal. 2017 Sep 10;27(8):489-509. doi: 10.1089/ars.2016.6851. Epub 2017 Mar 9.

37.

Comparison of Survival Outcomes Among Human Papillomavirus-Negative cT1-2 N1-2b Patients With Oropharyngeal Squamous Cell Cancer Treated With Upfront Surgery vs Definitive Chemoradiation Therapy: An Observational Study.

Kelly JR, Park HS, An Y, Contessa JN, Yarbrough WG, Burtness BA, Decker R, Husain Z.

JAMA Oncol. 2017 Aug 1;3(8):1107-1111. doi: 10.1001/jamaoncol.2016.5769.

38.

LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro.

Wamsley JJ, Issaeva N, An H, Lu X, Donehower LA, Yarbrough WG.

Cell Cycle. 2017 Jan 17;16(2):213-223. doi: 10.1080/15384101.2016.1261767. Epub 2016 Dec 27.

39.

LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer).

Simonik EA, Cai Y, Kimmelshue KN, Brantley-Sieders DM, Loomans HA, Andl CD, Westlake GM, Youngblood VM, Chen J, Yarbrough WG, Brown BT, Nagarajan L, Brandt SJ.

PLoS One. 2016 Oct 25;11(10):e0164804. doi: 10.1371/journal.pone.0164804. eCollection 2016.

40.

Selective antitumor activity of roscovitine in head and neck cancer.

Gary C, Hajek M, Biktasova A, Bellinger G, Yarbrough WG, Issaeva N.

Oncotarget. 2016 Jun 21;7(25):38598-38611. doi: 10.18632/oncotarget.9560.

41.

Proposing prognostic thresholds for lymph node yield in clinically lymph node-negative and lymph node-positive cancers of the oral cavity.

Kuo P, Mehra S, Sosa JA, Roman SA, Husain ZA, Burtness BA, Tate JP, Yarbrough WG, Judson BL.

Cancer. 2016 Dec 1;122(23):3624-3631. doi: 10.1002/cncr.30227. Epub 2016 Aug 1.

42.

Pretreatment predictors of adjuvant chemoradiation in patients receiving transoral robotic surgery for squamous cell carcinoma of the oropharynx: a case control study.

Subramanian HE, Park HS, Barbieri A, Mahajan A, Judson BL, Mehra S, Yarbrough WG, Burtness BA, Husain ZA.

Cancers Head Neck. 2016 Jul 4;1:7. doi: 10.1186/s41199-016-0008-7. eCollection 2016.

43.

NOTCH1 and SOX10 are Essential for Proliferation and Radiation Resistance of Cancer Stem-Like Cells in Adenoid Cystic Carcinoma.

Panaccione A, Chang MT, Carbone BE, Guo Y, Moskaluk CA, Virk RK, Chiriboga L, Prasad ML, Judson B, Mehra S, Yarbrough WG, Ivanov SV.

Clin Cancer Res. 2016 Apr 15;22(8):2083-95. doi: 10.1158/1078-0432.CCR-15-2208.

44.

Treatment trends and survival effects of chemotherapy for hypopharyngeal cancer: Analysis of the National Cancer Data Base.

Kuo P, Sosa JA, Burtness BA, Husain ZA, Mehra S, Roman SA, Yarbrough WG, Judson BL.

Cancer. 2016 Jun 15;122(12):1853-60. doi: 10.1002/cncr.29962. Epub 2016 Mar 28.

45.

National treatment patterns in patients presenting with Stage IVC head and neck cancer: analysis of the National Cancer Database.

Schwam ZG, Burtness B, Yarbrough WG, Mehra S, Husain Z, Judson BL.

Cancer Med. 2015 Dec;4(12):1828-35. doi: 10.1002/cam4.546. Epub 2015 Oct 16.

46.

Mitochondria, calcium, and tumor suppressor Fus1: At the crossroad of cancer, inflammation, and autoimmunity.

Uzhachenko R, Shanker A, Yarbrough WG, Ivanova AV.

Oncotarget. 2015 Aug 28;6(25):20754-72. Review.

47.

Detection and genotype of high-risk human papillomavirus in fine-needle aspirates of patients with metastatic squamous cell carcinoma is helpful in determining tumor origin.

Baldassarri R, Aronberg R, Levi AW, Yarbrough WG, Kowalski D, Chhieng D.

Am J Clin Pathol. 2015 May;143(5):694-700. doi: 10.1309/AJCPCZA4PSZCFHQ4.

PMID:
25873503
48.

Lymphatic drainage patterns in oral squamous cell carcinoma: findings of the ACOSOG Z0360 (Alliance) study.

Farmer RW, McCall L, Civantos FJ, Myers JN, Yarbrough WG, Murphy B, O'Leary M, Zitsch R, Siegel BA.

Otolaryngol Head Neck Surg. 2015 Apr;152(4):673-7. doi: 10.1177/0194599815572585. Epub 2015 Mar 6.

49.

Cellular oxidative stress response mediates radiosensitivity in Fus1-deficient mice.

Yazlovitskaya EM, Voziyan PA, Manavalan T, Yarbrough WG, Ivanova AV.

Cell Death Dis. 2015 Feb 19;6:e1652. doi: 10.1038/cddis.2014.593.

50.

Negative regulation of RelA phosphorylation: emerging players and their roles in cancer.

Lu X, Yarbrough WG.

Cytokine Growth Factor Rev. 2015 Feb;26(1):7-13. doi: 10.1016/j.cytogfr.2014.09.003. Epub 2014 Oct 2. Review.

PMID:
25438737

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