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Items: 1 to 50 of 171

1.

Low dose chloroquine decreases insulin resistance in human metabolic syndrome but does not reduce carotid intima-media thickness.

McGill JB, Johnson M, Hurst S, Cade WT, Yarasheski KE, Ostlund RE, Schechtman KB, Razani B, Kastan MB, McClain DA, de Las Fuentes L, Davila-Roman VG, Ory DS, Wickline SA, Semenkovich CF.

Diabetol Metab Syndr. 2019 Jul 29;11:61. doi: 10.1186/s13098-019-0456-4. eCollection 2019.

2.

Dissemination and Implementation Program in Hypertension in Rwanda: Report on Initial Training and Evaluation.

Baumann AA, Mutabazi V, Brown AL, Hooley C, Reeds D, Ingabire C, Ndahindwa V, Nishimwe A, Cade WT, de Las Fuentes L, Proctor EK, Karengera S, Schecthman KB, Goss CW, Yarasheski K, Newsome B, Mutimura E, Davila-Roman VG.

Glob Heart. 2019 Jun;14(2):135-141. doi: 10.1016/j.gheart.2019.06.001.

PMID:
31324367
3.

Aerobic Plus Resistance Exercise in Obese Older Adults Improves Muscle Protein Synthesis and Preserves Myocellular Quality Despite Weight Loss.

Colleluori G, Aguirre L, Phadnis U, Fowler K, Armamento-Villareal R, Sun Z, Brunetti L, Hyoung Park J, Kaipparettu BA, Putluri N, Auetumrongsawat V, Yarasheski K, Qualls C, Villareal DT.

Cell Metab. 2019 Aug 6;30(2):261-273.e6. doi: 10.1016/j.cmet.2019.06.008. Epub 2019 Jul 3.

PMID:
31279675
4.

SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases.

Paterson RW, Gabelle A, Lucey BP, Barthélemy NR, Leckey CA, Hirtz C, Lehmann S, Sato C, Patterson BW, West T, Yarasheski K, Rohrer JD, Wildburger NC, Schott JM, Karch CM, Wray S, Miller TM, Elbert DL, Zetterberg H, Fox NC, Bateman RJ.

Nat Rev Neurol. 2019 Jul;15(7):419-427. doi: 10.1038/s41582-019-0222-0. Epub 2019 Jun 20. Review.

PMID:
31222062
5.

A Randomized, Double-blinded, Placebo-controlled Trial of Sitagliptin for Reducing Inflammation and Immune Activation in Treated and Suppressed Human Immunodeficiency Virus Infection.

Dubé MP, Chan ES, Lake JE, Williams B, Kinslow J, Landay A, Coombs RW, Floris-Moore M, Ribaudo HJ, Yarasheski KE.

Clin Infect Dis. 2019 Sep 13;69(7):1165-1172. doi: 10.1093/cid/ciy1051.

PMID:
30535188
6.

Tau Kinetics in Neurons and the Human Central Nervous System.

Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, Karch CM, Bateman RJ.

Neuron. 2018 May 16;98(4):861-864. doi: 10.1016/j.neuron.2018.04.035. No abstract available.

7.

Tau Kinetics in Neurons and the Human Central Nervous System.

Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, Karch CM, Bateman RJ.

Neuron. 2018 Mar 21;97(6):1284-1298.e7. doi: 10.1016/j.neuron.2018.02.015. Erratum in: Neuron. 2018 May 16;98 (4):861-864.

8.

HIV infection does not prevent the metabolic benefits of diet-induced weight loss in women with obesity.

Reeds DN, Pietka TA, Yarasheski KE, Cade WT, Patterson BW, Okunade A, Abumrad NA, Klein S.

Obesity (Silver Spring). 2017 Apr;25(4):682-688. doi: 10.1002/oby.21793. Epub 2017 Feb 28.

9.

SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy.

Mayer AL, Higgins CB, Heitmeier MR, Kraft TE, Qian X, Crowley JR, Hyrc KL, Beatty WL, Yarasheski KE, Hruz PW, DeBosch BJ.

Sci Rep. 2016 Dec 6;6:38586. doi: 10.1038/srep38586.

10.

Frailty in HIV: Epidemiology, Biology, Measurement, Interventions, and Research Needs.

Piggott DA, Erlandson KM, Yarasheski KE.

Curr HIV/AIDS Rep. 2016 Dec;13(6):340-348. Review.

11.

Extracellular pH Modulates Neuroendocrine Prostate Cancer Cell Metabolism and Susceptibility to the Mitochondrial Inhibitor Niclosamide.

Ippolito JE, Brandenburg MW, Ge X, Crowley JR, Kirmess KM, Som A, D'Avignon DA, Arbeit JM, Achilefu S, Yarasheski KE, Milbrandt J.

PLoS One. 2016 Jul 20;11(7):e0159675. doi: 10.1371/journal.pone.0159675. eCollection 2016.

12.

Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis.

DeBosch BJ, Heitmeier MR, Mayer AL, Higgins CB, Crowley JR, Kraft TE, Chi M, Newberry EP, Chen Z, Finck BN, Davidson NO, Yarasheski KE, Hruz PW, Moley KH.

Sci Signal. 2016 Feb 23;9(416):ra21. doi: 10.1126/scisignal.aac5472.

13.

How sweet is acute exercise after pure fructose ingestion?

Yarasheski KE, Parks EJ.

Am J Clin Nutr. 2016 Feb;103(2):301-2. doi: 10.3945/ajcn.115.126516. Epub 2016 Jan 13. No abstract available.

PMID:
26762370
14.

In vivo kinetic approach reveals slow SOD1 turnover in the CNS.

Crisp MJ, Mawuenyega KG, Patterson BW, Reddy NC, Chott R, Self WK, Weihl CC, Jockel-Balsarotti J, Varadhachary AS, Bucelli RC, Yarasheski KE, Bateman RJ, Miller TM.

J Clin Invest. 2015 Jul 1;125(7):2772-80. doi: 10.1172/JCI80705. Epub 2015 Jun 15.

15.

Age and amyloid effects on human central nervous system amyloid-beta kinetics.

Patterson BW, Elbert DL, Mawuenyega KG, Kasten T, Ovod V, Ma S, Xiong C, Chott R, Yarasheski K, Sigurdson W, Zhang L, Goate A, Benzinger T, Morris JC, Holtzman D, Bateman RJ.

Ann Neurol. 2015 Sep;78(3):439-53. doi: 10.1002/ana.24454. Epub 2015 Jul 20.

16.

Sitagliptin Reduces Inflammation and Chronic Immune Cell Activation in HIV+ Adults With Impaired Glucose Tolerance.

Best C, Struthers H, Laciny E, Royal M, Reeds DN, Yarasheski KE.

J Clin Endocrinol Metab. 2015 Jul;100(7):2621-9. doi: 10.1210/jc.2015-1531. Epub 2015 May 4.

17.

Reply to comment on "An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice".

Sheline YI, West T, Yarasheski K, Jasielec MS, Hettinger JC, Tripoli DL, Xiong C, Frederiksen C, Grzelak MV, Bateman RJ, Morris JC, Lee JM, Cirrito JR.

Sci Transl Med. 2014 Dec 24;6(268):268lr4. doi: 10.1126/scitranslmed.3010609. No abstract available.

18.

Testosterone Supplementation Improves Carbohydrate and Lipid Metabolism in Some Older Men with Abdominal Obesity.

Sattler F, He J, Chukwuneke J, Kim H, Stewart Y, Colletti P, Yarasheski K, Buchanan T.

J Gerontol Geriatr Res. 2014 Jun 7;3(3):1000159.

19.

CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition.

Dobrowolska JA, Michener MS, Wu G, Patterson BW, Chott R, Ovod V, Pyatkivskyy Y, Wildsmith KR, Kasten T, Mathers P, Dancho M, Lennox C, Smith BE, Gilberto D, McLoughlin D, Holder DJ, Stamford AW, Yarasheski KE, Kennedy ME, Savage MJ, Bateman RJ.

J Neurosci. 2014 Jun 11;34(24):8336-46. doi: 10.1523/JNEUROSCI.0540-14.2014.

20.

An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice.

Sheline YI, West T, Yarasheski K, Swarm R, Jasielec MS, Fisher JR, Ficker WD, Yan P, Xiong C, Frederiksen C, Grzelak MV, Chott R, Bateman RJ, Morris JC, Mintun MA, Lee JM, Cirrito JR.

Sci Transl Med. 2014 May 14;6(236):236re4. doi: 10.1126/scitranslmed.3008169.

21.

Microbial community dynamics and stability during an ammonia-induced shift to syntrophic acetate oxidation.

Werner JJ, Garcia ML, Perkins SD, Yarasheski KE, Smith SR, Muegge BD, Stadermann FJ, DeRito CM, Floss C, Madsen EL, Gordon JI, Angenent LT.

Appl Environ Microbiol. 2014 Jun;80(11):3375-83. doi: 10.1128/AEM.00166-14. Epub 2014 Mar 21.

22.

Pilot study of pioglitazone and exercise training effects on basal myocardial substrate metabolism and left ventricular function in HIV-positive individuals with metabolic complications.

Cade WT, Reeds DN, Overton ET, Herrero P, Waggoner AD, Laciny E, Bopp C, Lassa-Claxton S, Gropler RJ, Peterson LR, Yarasheski KE.

HIV Clin Trials. 2013 Nov-Dec;14(6):303-12. doi: 10.1310/hct1406-303.

23.

Cardiometabolic risks during anabolic hormone supplementation in older men.

He J, Bhasin S, Binder EF, Yarasheski KE, Castaneda-Sceppa C, Schroeder ET, Roubenoff R, Chou CP, Azen SP, Sattler FR.

Obesity (Silver Spring). 2013 May;21(5):968-75. doi: 10.1002/oby.20081.

24.

Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers.

Potter R, Patterson BW, Elbert DL, Ovod V, Kasten T, Sigurdson W, Mawuenyega K, Blazey T, Goate A, Chott R, Yarasheski KE, Holtzman DM, Morris JC, Benzinger TL, Bateman RJ.

Sci Transl Med. 2013 Jun 12;5(189):189ra77. doi: 10.1126/scitranslmed.3005615.

25.

Relationships among HIV infection, metabolic risk factors, and left ventricular structure and function.

Cade WT, Overton ET, Mondy K, de las Fuentes L, Davila-Roman VG, Waggoner AD, Reeds DN, Lassa-Claxton S, Krauss MJ, Peterson LR, Yarasheski KE.

AIDS Res Hum Retroviruses. 2013 Aug;29(8):1151-60. doi: 10.1089/AID.2012.0254. Epub 2013 May 6.

26.

Gastric cancer in Zambian adults: a prospective case-control study that assessed dietary intake and antioxidant status by using urinary isoprostane excretion.

Asombang AW, Kayamba V, Mwanza-Lisulo M, Colditz G, Mudenda V, Yarasheski K, Chott R, Rubin DC, Gyawali CP, Sinkala E, Mwanamakondo S, Anderson-Spearie C, Kelly P.

Am J Clin Nutr. 2013 May;97(5):1029-35. doi: 10.3945/ajcn.112.051284. Epub 2013 Mar 27.

27.

Age attenuates leucine oxidation after eccentric exercise.

Kullman EL, Campbell WW, Krishnan RK, Yarasheski KE, Evans WJ, Kirwan JP.

Int J Sports Med. 2013 Aug;34(8):695-9. doi: 10.1055/s-0032-1327659. Epub 2013 Jan 16.

28.

Dipeptidyl peptidase IV inhibition does not adversely affect immune or virological status in HIV infected men and women: a pilot safety study.

Goodwin SR, Reeds DN, Royal M, Struthers H, Laciny E, Yarasheski KE.

J Clin Endocrinol Metab. 2013 Feb;98(2):743-51. doi: 10.1210/jc.2012-3532. Epub 2012 Dec 21.

29.

Age and sex affect protein metabolism at protein intakes that span the range of adequacy: comparison of leucine kinetics and nitrogen balance data.

Conley TB, McCabe GP, Lim E, Yarasheski KE, Johnson CA, Campbell WW.

J Nutr Biochem. 2013 Apr;24(4):693-9. doi: 10.1016/j.jnutbio.2012.03.021. Epub 2012 Jul 26.

30.

Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells.

Everts B, Amiel E, van der Windt GJ, Freitas TC, Chott R, Yarasheski KE, Pearce EL, Pearce EJ.

Blood. 2012 Aug 16;120(7):1422-31. doi: 10.1182/blood-2012-03-419747. Epub 2012 Jul 11.

31.

18FDG PET-CT imaging detects arterial inflammation and early atherosclerosis in HIV-infected adults with cardiovascular disease risk factors.

Yarasheski KE, Laciny E, Overton ET, Reeds DN, Harrod M, Baldwin S, Dávila-Román VG.

J Inflamm (Lond). 2012 Jun 22;9(1):26. doi: 10.1186/1476-9255-9-26.

32.

In vivo human apolipoprotein E isoform fractional turnover rates in the CNS.

Wildsmith KR, Basak JM, Patterson BW, Pyatkivskyy Y, Kim J, Yarasheski KE, Wang JX, Mawuenyega KG, Jiang H, Parsadanian M, Yoon H, Kasten T, Sigurdson WC, Xiong C, Goate A, Holtzman DM, Bateman RJ.

PLoS One. 2012;7(6):e38013. doi: 10.1371/journal.pone.0038013. Epub 2012 Jun 4.

33.

Effects of human immunodeficiency virus and metabolic complications on myocardial nutrient metabolism, blood flow, and oxygen consumption: a cross-sectional analysis.

Cade WT, Reeds DN, Overton ET, Herrero P, Waggoner AD, Davila-Roman VG, Lassa-Claxton S, Gropler RJ, Soto PF, Krauss MJ, Yarasheski KE, Peterson LR.

Cardiovasc Diabetol. 2011 Dec 8;10:111. doi: 10.1186/1475-2840-10-111.

34.

Value of measuring muscle performance to assess changes in lean mass with testosterone and growth hormone supplementation.

Schroeder ET, He J, Yarasheski KE, Binder EF, Castaneda-Sceppa C, Bhasin S, Dieli-Conwright CM, Kawakubo M, Roubenoff R, Azen SP, Sattler FR.

Eur J Appl Physiol. 2012 Mar;112(3):1123-31. doi: 10.1007/s00421-011-2077-y. Epub 2011 Jul 12.

35.

Whole-body and muscle protein metabolism are not affected by acute deviations from habitual protein intake in older men: the Hormonal Regulators of Muscle and Metabolism in Aging (HORMA) Study.

Yarasheski KE, Castaneda-Sceppa C, He J, Kawakubo M, Bhasin S, Binder EF, Schroeder ET, Roubenoff R, Azen SP, Sattler FR.

Am J Clin Nutr. 2011 Jul;94(1):172-81. doi: 10.3945/ajcn.110.010959. Epub 2011 May 4.

36.

Durability of the effects of testosterone and growth hormone supplementation in older community-dwelling men: the HORMA Trial.

Sattler FR, Bhasin S, He J, Yarasheski KE, Binder EF, Schroeder ET, Castaneda-Sceppa C, Kawakubo M, Roubenoff R, Dunn M, Hahn C, Stewart Y, Martinez C, Azen SP.

Clin Endocrinol (Oxf). 2011 Jul;75(1):103-11. doi: 10.1111/j.1365-2265.2011.04014.x.

37.

Evaluation of early biomarkers of muscle anabolic response to testosterone.

Chen F, Lam R, Shaywitz D, Hendrickson RC, Opiteck GJ, Wishengrad D, Liaw A, Song Q, Stewart AJ, Cummings CE, Beals C, Yarasheski KE, Reicin A, Ruddy M, Hu X, Yates NA, Menetski J, Herman GA.

J Cachexia Sarcopenia Muscle. 2011 Mar;2(1):45-56. Epub 2011 Feb 26.

38.

Bacterial community structures are unique and resilient in full-scale bioenergy systems.

Werner JJ, Knights D, Garcia ML, Scalfone NB, Smith S, Yarasheski K, Cummings TA, Beers AR, Knight R, Angenent LT.

Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4158-63. doi: 10.1073/pnas.1015676108. Epub 2011 Feb 22.

39.

Age-related skeletal muscle decline is similar in HIV-infected and uninfected individuals.

Yarasheski KE, Scherzer R, Kotler DP, Dobs AS, Tien PC, Lewis CE, Kronmal RA, Heymsfield SB, Bacchetti P, Grunfeld C; Study of Fat Redistribution and Metabolic Change in HIV Infection (FRAM).

J Gerontol A Biol Sci Med Sci. 2011 Mar;66(3):332-40. doi: 10.1093/gerona/glq228. Epub 2011 Feb 10.

40.

Decreased clearance of CNS beta-amyloid in Alzheimer's disease.

Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, Yarasheski KE, Bateman RJ.

Science. 2010 Dec 24;330(6012):1774. doi: 10.1126/science.1197623. Epub 2010 Dec 9.

41.

Testosterone threshold levels and lean tissue mass targets needed to enhance skeletal muscle strength and function: the HORMA trial.

Sattler F, Bhasin S, He J, Chou CP, Castaneda-Sceppa C, Yarasheski K, Binder E, Schroeder ET, Kawakubo M, Zhang A, Roubenoff R, Azen S.

J Gerontol A Biol Sci Med Sci. 2011 Jan;66(1):122-9. doi: 10.1093/gerona/glq183. Epub 2010 Nov 8.

42.

Exercise training augments the peripheral insulin-sensitizing effects of pioglitazone in HIV-infected adults with insulin resistance and central adiposity.

Yarasheski KE, Cade WT, Overton ET, Mondy KE, Hubert S, Laciny E, Bopp C, Lassa-Claxton S, Reeds DN.

Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E243-51. doi: 10.1152/ajpendo.00468.2010. Epub 2010 Oct 19.

43.

Impact of viral-mediated IGF-I gene transfer on skeletal muscle following cast immobilization.

Stevens-Lapsley JE, Ye F, Liu M, Borst SE, Conover C, Yarasheski KE, Walter GA, Sweeney HL, Vandenborne K.

Am J Physiol Endocrinol Metab. 2010 Nov;299(5):E730-40. doi: 10.1152/ajpendo.00230.2010. Epub 2010 Aug 24.

44.

Acute gamma-secretase inhibition of nonhuman primate CNS shifts amyloid precursor protein (APP) metabolism from amyloid-beta production to alternative APP fragments without amyloid-beta rebound.

Cook JJ, Wildsmith KR, Gilberto DB, Holahan MA, Kinney GG, Mathers PD, Michener MS, Price EA, Shearman MS, Simon AJ, Wang JX, Wu G, Yarasheski KE, Bateman RJ.

J Neurosci. 2010 May 12;30(19):6743-50. doi: 10.1523/JNEUROSCI.1381-10.2010.

45.

HIV-protease inhibitors suppress skeletal muscle fatty acid oxidation by reducing CD36 and CPT1 fatty acid transporters.

Richmond SR, Carper MJ, Lei X, Zhang S, Yarasheski KE, Ramanadham S.

Biochim Biophys Acta. 2010 May;1801(5):559-66. doi: 10.1016/j.bbalip.2010.01.007. Epub 2010 Feb 1.

46.

Yoga lifestyle intervention reduces blood pressure in HIV-infected adults with cardiovascular disease risk factors.

Cade WT, Reeds DN, Mondy KE, Overton ET, Grassino J, Tucker S, Bopp C, Laciny E, Hubert S, Lassa-Claxton S, Yarasheski KE.

HIV Med. 2010 Jul 1;11(6):379-88. doi: 10.1111/j.1468-1293.2009.00801.x. Epub 2010 Jan 5.

47.

N-terminal propeptide of type III procollagen as a biomarker of anabolic response to recombinant human GH and testosterone.

Bhasin S, He EJ, Kawakubo M, Schroeder ET, Yarasheski K, Opiteck GJ, Reicin A, Chen F, Lam R, Tsou JA, Castaneda-Sceppa C, Binder EF, Azen SP, Sattler FR.

J Clin Endocrinol Metab. 2009 Nov;94(11):4224-33. doi: 10.1210/jc.2009-1434. Epub 2009 Oct 16.

48.

1H-magnetic resonance spectroscopy for quantifying myocardial lipid content in humans with the cardiometabolic syndrome.

O'Connor RD, Bashir A, Cade WT, Yarasheski KE, Gropler RJ.

J Clin Hypertens (Greenwich). 2009 Sep;11(9):528-32. doi: 10.1111/j.1559-4572.2009.00061.x. No abstract available.

49.

A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system.

Bateman RJ, Siemers ER, Mawuenyega KG, Wen G, Browning KR, Sigurdson WC, Yarasheski KE, Friedrich SW, Demattos RB, May PC, Paul SM, Holtzman DM.

Ann Neurol. 2009 Jul;66(1):48-54. doi: 10.1002/ana.21623.

50.

Peripheral and visceral fat changes following a treatment switch to a non-thymidine analogue or a nucleoside-sparing regimen in HIV-infected subjects with peripheral lipoatrophy: results of ACTG A5110.

Tebas P, Zhang J, Hafner R, Tashima K, Shevitz A, Yarasheski K, Berzins B, Owens S, Forand J, Evans S, Murphy R.

J Antimicrob Chemother. 2009 May;63(5):998-1005. doi: 10.1093/jac/dkp071. Epub 2009 Mar 19.

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