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The MEK Inhibitor Trametinib Ameliorates Kidney Fibrosis by Suppressing ERK1/2 and mTORC1 Signaling.

Andrikopoulos P, Kieswich J, Pacheco S, Nadarajah L, Harwood SM, O'Riordan CE, Thiemermann C, Yaqoob MM.

J Am Soc Nephrol. 2018 Dec 10. pii: ASN.2018020209. doi: 10.1681/ASN.2018020209. [Epub ahead of print]


A novel model of reno-cardiac syndrome in the C57BL/ 6 mouse strain.

Kieswich JE, Chen J, Alliouachene S, Caton PW, McCafferty K, Thiemermann C, Yaqoob MM.

BMC Nephrol. 2018 Dec 4;19(1):346. doi: 10.1186/s12882-018-1155-3.


Novel mutation G324C in WNT1 mapped in a large Pakistani family with severe recessively inherited Osteogenesis Imperfecta.

Kausar M, Siddiqi S, Yaqoob M, Mansoor S, Makitie O, Mir A, Khor CC, Foo JN, Anees M.

J Biomed Sci. 2018 Nov 17;25(1):82. doi: 10.1186/s12929-018-0481-x.


Surfactant enhanced flow injection chemiluminescence method for vitamin D3 determination in pharmaceutical formulations.

Khan F, Yaqoob M, Asghar M, Iqbal S, Ali S, Waseem A, Nabi A.

Spectrochim Acta A Mol Biomol Spectrosc. 2019 Feb 5;208:150-156. doi: 10.1016/j.saa.2018.10.001. Epub 2018 Oct 4.


Impact of Transplant Nephrectomy for Patient Survival Over the Past 15 Years: A Single-Center Study.

Muramatsu M, Hyodo Y, Sheaff M, Aikawa A, Yaqoob M, Puliatti C.

Exp Clin Transplant. 2018 Oct 5. doi: 10.6002/ect.2018.0233. [Epub ahead of print]


Fate, distribution, and bioconcentration of pesticides impact on the organic farms of Cameron Highlands, Malaysia.

Farina Y, Munawar N, Abdullah MP, Yaqoob M, Nabi A.

Environ Monit Assess. 2018 Jun 9;190(7):386. doi: 10.1007/s10661-018-6762-8.


Trends in Avoidable Hospitalizations for Diabetes: Experience of a Large Clinically Integrated Health Care System.

Yaqoob M, Wang J, Sweeney AT, Wells C, Rego V, Jaber BL.

J Healthc Qual. 2018 Jun 4. doi: 10.1097/JHQ.0000000000000145. [Epub ahead of print]


Healthcare use, costs and quality of life in patients with end-stage kidney disease receiving conservative management: results from a multi-centre observational study (PACKS).

Phair G, Agus A, Normand C, Brazil K, Burns A, Roderick P, Maxwell AP, Thompson C, Yaqoob M, Noble H.

Palliat Med. 2018 Sep;32(8):1401-1409. doi: 10.1177/0269216318775247. Epub 2018 May 16.


Letter by Mitchell et al Regarding Article, "Urinary Prostaglandin Metabolites: An Incomplete Reckoning and a Flush to Judgment".

Mitchell JA, Knowles RB, Kirkby NS, Reed DM, Edin ML, White WE, Chan MV, Longhurst H, Yaqoob MM, Milne GL, Zeldin DC, Warner TD.

Circ Res. 2018 May 11;122(10):e84-e85. doi: 10.1161/CIRCRESAHA.118.312976. No abstract available.


Systematic Review and the External Validity of Randomized Controlled Trials in Lupus Nephritis.

Pakozdi A, Rajakariar R, Pyne D, Cove-Smith A, Yaqoob MM.

Kidney Int Rep. 2017 Nov 16;3(2):403-411. doi: 10.1016/j.ekir.2017.11.005. eCollection 2018 Mar.


Impact of Allograft Nephrectomy on Second Renal Transplant Outcome.

Muramatsu M, Hyodo Y, Sheaff M, Gupta A, Ashman N, Aikawa A, Yaqoob M, Puliatti C.

Exp Clin Transplant. 2018 Jun;16(3):259-265. doi: 10.6002/ect.2018.0046. Epub 2018 Apr 20.


Ethnic differences in the progression of chronic kidney disease and risk of death in a UK diabetic population: an observational cohort study.

Mathur R, Dreyer G, Yaqoob MM, Hull SA.

BMJ Open. 2018 Mar 27;8(3):e020145. doi: 10.1136/bmjopen-2017-020145.


Nephrotic syndrome in adults.

Mahalingasivam V, Booth J, Sheaff M, Yaqoob M.

Acute Med. 2018;17(1):36-43. Review.


Safety of fenbendazole in common peafowl (Pavo cristatus).

Umar S, Abbas S, Khan MI, Nisa Q, Younus M, Aqil K, Qayyum R, Yaqoob M, Ali A, Yaseen MA, Shah MA.

Pak J Pharm Sci. 2018 Jan;31(1):159-167.


Genetic characterization of phenicol-resistant Escherichia coli and role of wild-type repressor/regulator gene (acrR) on phenicol resistance.

Yaqoob M, Wang LP, Kashif J, Memon J, Umar S, Iqbal MF, Fiaz M, Lu CP.

Folia Microbiol (Praha). 2018 Jul;63(4):443-449. doi: 10.1007/s12223-017-0579-7. Epub 2018 Jan 6.


Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M.

Mitchell JA, Knowles RB, Kirkby NS, Reed DM, Edin ML, White WE, Chan MV, Longhurst H, Yaqoob MM, Milne GL, Zeldin DC, Warner TD.

Circ Res. 2018 Feb 16;122(4):555-559. doi: 10.1161/CIRCRESAHA.117.312144. Epub 2018 Jan 3.


Flow Injection-Chemiluminescence Method for Determination of Hyoscine Butylbromide Using Silver(III) as Oxidizing Agent.

Ahmed M, Asghar M, Yaqoob M, Munawar N, Shahid F, Asad M, Nabi A.

Anal Sci. 2017;33(11):1259-1263. doi: 10.2116/analsci.33.1259.


Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes.

Purvis GSD, Chiazza F, Chen J, Azevedo-Loiola R, Martin L, Kusters DHM, Reutelingsperger C, Fountoulakis N, Gnudi L, Yaqoob MM, Collino M, Thiemermann C, Solito E.

Diabetologia. 2018 Feb;61(2):482-495. doi: 10.1007/s00125-017-4469-y. Epub 2017 Oct 30.


Entirely S-protected chitosan: A promising mucoadhesive excipient for metronidazole vaginal tablets.

Lupo N, Fodor B, Muhammad I, Yaqoob M, Matuszczak B, Bernkop-Schnürch A.

Acta Biomater. 2017 Dec;64:106-115. doi: 10.1016/j.actbio.2017.10.014. Epub 2017 Oct 10.


Eye and foot checks in patients with diabetes on haemodialysis: Are they done, and who does them?

Mothojakan NB, Hussain S, McCafferty K, Yaqoob MM, Chowdhury TA.

World J Diabetes. 2017 Sep 15;8(9):436-439. doi: 10.4239/wjd.v8.i9.436.


Ischemic conditioning in solid organ transplantation: is it worth giving your right arm for?

Nadarajah L, Yaqoob MM, McCafferty K.

Curr Opin Nephrol Hypertens. 2017 Nov;26(6):467-476. doi: 10.1097/MNH.0000000000000367. Review.


Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis.

Johnson FL, Patel NSA, Purvis GSD, Chiazza F, Chen J, Sordi R, Hache G, Merezhko VV, Collino M, Yaqoob MM, Thiemermann C.

J Am Heart Assoc. 2017 Jul 3;6(7). pii: e005092. doi: 10.1161/JAHA.116.005092.


Membranous nephropathy: a retrospective observational study of membranous nephropathy in north east and central London.

Gupta S, Connolly J, Pepper RJ, Walsh SB, Yaqoob MM, Kleta R, Ashman N.

BMC Nephrol. 2017 Jun 21;18(1):201. doi: 10.1186/s12882-017-0615-5.


Coupling between the TRPC3 ion channel and the NCX1 transporter contributed to VEGF-induced ERK1/2 activation and angiogenesis in human primary endothelial cells.

Andrikopoulos P, Eccles SA, Yaqoob MM.

Cell Signal. 2017 Sep;37:12-30. doi: 10.1016/j.cellsig.2017.05.013. Epub 2017 May 20.


Clinician views of patient decisional conflict when deciding between dialysis and conservative management: Qualitative findings from the PAlliative Care in chronic Kidney diSease (PACKS) study.

Noble H, Brazil K, Burns A, Hallahan S, Normand C, Roderick P, Thompson C, Maxwell P, Yaqoob M.

Palliat Med. 2017 Dec;31(10):921-931. doi: 10.1177/0269216317704625. Epub 2017 Apr 18.


Could metformin be used in patients with diabetes and advanced chronic kidney disease?

Chowdhury TA, Srirathan D, Abraham G, Oei EL, Fan SL, McCafferty K, Yaqoob MM.

Diabetes Obes Metab. 2017 Feb;19(2):156-161. doi: 10.1111/dom.12799. Epub 2016 Nov 9. Review.


Monomeric eNAMPT in the development of experimental diabetes in mice: a potential target for type 2 diabetes treatment.

Kieswich J, Sayers SR, Silvestre MF, Harwood SM, Yaqoob MM, Caton PW.

Diabetologia. 2016 Nov;59(11):2477-2486. doi: 10.1007/s00125-016-4076-3. Epub 2016 Aug 19.


Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation.

Bagnati M, Ogunkolade BW, Marshall C, Tucci C, Hanna K, Jones TA, Bugliani M, Nedjai B, Caton PW, Kieswich J, Yaqoob MM, Ball GR, Marchetti P, Hitman GA, Turner MD.

Cell Death Dis. 2016 Aug 11;7(8):e2329. doi: 10.1038/cddis.2016.203.


Myocardial bioenergetic abnormalities in experimental uremia.

Chesser AM, Harwood SM, Raftery MJ, Yaqoob MM.

Int J Nephrol Renovasc Dis. 2016 May 24;9:129-37. doi: 10.2147/IJNRD.S89926. eCollection 2016.


IκB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD.

Chen J, Kieswich JE, Chiazza F, Moyes AJ, Gobbetti T, Purvis GS, Salvatori DC, Patel NS, Perretti M, Hobbs AJ, Collino M, Yaqoob MM, Thiemermann C.

J Am Soc Nephrol. 2017 Jan;28(1):94-105. doi: 10.1681/ASN.2015060670. Epub 2016 May 6.


Challenges in Implementation of the ANISA Protocol at the Matiari Site, Pakistan.

Ahmed S, Ariff S, Soofi SB, Hussain A, Hotwani A, Yaqoob M, Qureshi SM, Ahmed I, Islam MS, Saha SK, Bhutta ZA.

Pediatr Infect Dis J. 2016 May;35(5 Suppl 1):S65-9. doi: 10.1097/INF.0000000000001110.


Development of oral self nano-emulsifying delivery system(s) of lanreotide with improved stability against presystemic thiol-disulfide exchange reactions.

Ijaz M, Bonengel S, Zupančič O, Yaqoob M, Hartl M, Hussain S, Huck CW, Bernkop-Schnürch A.

Expert Opin Drug Deliv. 2016 Jul;13(7):923-9. doi: 10.1517/17425247.2016.1167034. Epub 2016 Apr 7.


Synergistic effects of thymoquinone and curcumin on immune response and anti-viral activity against avian influenza virus (H9N2) in turkeys.

Umar S, Shah MA, Munir MT, Yaqoob M, Fiaz M, Anjum S, Kaboudi K, Bouzouaia M, Younus M, Nisa Q, Iqbal M, Umar W.

Poult Sci. 2016 Jul 1;95(7):1513-20. doi: 10.3382/ps/pew069. Epub 2016 Mar 4.


Nurses' care practices at the end of life in intensive care units in Bahrain.

O'Neill CS, Yaqoob M, Faraj S, O'Neill CL.

Nurs Ethics. 2017 Dec;24(8):950-961. doi: 10.1177/0969733016629771. Epub 2016 Feb 22.


Managing blood glucose levels in patients with diabetes and renal impairment.

Chowdhury TA, O'Toole S, Yaqoob MM.

Br J Hosp Med (Lond). 2016 Jan;77(1):C10-3. doi: 10.12968/hmed.2016.77.1.C10. Review. No abstract available.


What do patients need to know? A study to assess patients' satisfaction with information about medicines.

Twigg MJ, Bhattacharya D, Clark A, Patel R, Rogers H, Whiteside H, Yaqoob M, Wright DJ.

Int J Pharm Pract. 2016 Aug;24(4):229-36. doi: 10.1111/ijpp.12252. Epub 2016 Feb 15.


The Authors Reply.

Gallagher SM, Archbold RA, Jones DA, Wragg A, Uppal R, Yaqoob MM.

Kidney Int. 2015 Nov;88(5):1195-6. doi: 10.1038/ki.2015.263. No abstract available.


Macrophage Blockade Using CSF1R Inhibitors Reverses the Vascular Leakage Underlying Malignant Ascites in Late-Stage Epithelial Ovarian Cancer.

Moughon DL, He H, Schokrpur S, Jiang ZK, Yaqoob M, David J, Lin C, Iruela-Arispe ML, Dorigo O, Wu L.

Cancer Res. 2015 Nov 15;75(22):4742-52. doi: 10.1158/0008-5472.CAN-14-3373. Epub 2015 Oct 15.


Estrogen protects the blood-brain barrier from inflammation-induced disruption and increased lymphocyte trafficking.

Maggioli E, McArthur S, Mauro C, Kieswich J, Kusters DH, Reutelingsperger CP, Yaqoob M, Solito E.

Brain Behav Immun. 2016 Jan;51:212-22. doi: 10.1016/j.bbi.2015.08.020. Epub 2015 Aug 29.


Ethnic/Race Diversity and Diabetic Kidney Disease.

Muthuppalaniappan VM, Yaqoob MM.

J Clin Med. 2015 Jul 31;4(8):1561-5. doi: 10.3390/jcm4081561. Review.


PAlliative Care in chronic Kidney diSease: the PACKS study--quality of life, decision making, costs and impact on carers in people managed without dialysis.

Noble HR, Agus A, Brazil K, Burns A, Goodfellow NA, Guiney M, McCourt F, McDowell C, Normand C, Roderick P, Thompson C, Maxwell AP, Yaqoob MM.

BMC Nephrol. 2015 Jul 11;16:104. doi: 10.1186/s12882-015-0084-7.


Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins.

Thomson S, Edin ML, Lih FB, Davies M, Yaqoob MM, Hammock BD, Gilroy D, Zeldin DC, Bishop-Bailey D.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):774-80. doi: 10.1016/j.bbrc.2015.06.012. Epub 2015 Jun 15.


Endothelial Angiogenesis and Barrier Function in Response to Thrombin Require Ca2+ Influx through the Na+/Ca2+ Exchanger.

Andrikopoulos P, Kieswich J, Harwood SM, Baba A, Matsuda T, Barbeau O, Jones K, Eccles SA, Yaqoob MM.

J Biol Chem. 2015 Jul 24;290(30):18412-28. doi: 10.1074/jbc.M114.628156. Epub 2015 May 15.


Using metformin in the presence of renal disease.

Chowdhury TA, Wright R, Yaqoob MM.

BMJ. 2015 Apr 14;350:h1758. doi: 10.1136/bmj.h1758. No abstract available.


Aging and uremia: Is there cellular and molecular crossover?

White WE, Yaqoob MM, Harwood SM.

World J Nephrol. 2015 Feb 6;4(1):19-30. doi: 10.5527/wjn.v4.i1.19. Review.


Determination of manganese- and manganese-containing fungicides with lucigenin-Tween-20-enhanced chemiluminescence detection.

Yaqoob M, Asghar M, Nabi A.

Luminescence. 2015 Nov;30(7):950-61. doi: 10.1002/bio.2844. Epub 2015 Jan 30.


Flow Injection Photosensitized Chemiluminescence of Luminol with Cu(II)-Rose Bengal: Mechanistic Approach and Vitamin A and C Determination.

Asgher M, Yaqoob M, Nabi A, Murtaza G, Siddiqi AR, Waseem A.

Int J Anal Chem. 2014;2014:109592. doi: 10.1155/2014/109592. Epub 2014 Dec 28.


The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities.

McCafferty K, Forbes S, Thiemermann C, Yaqoob MM.

Dis Model Mech. 2014 Dec;7(12):1321-33. doi: 10.1242/dmm.016741. Review.

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