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Items: 34

1.

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes.

Lin JR, Izar B, Wang S, Yapp C, Mei S, Shah PM, Santagata S, Sorger PK.

Elife. 2018 Jul 11;7. pii: e31657. doi: 10.7554/eLife.31657.

2.

Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.

Gerken PA, Wolstenhulme JR, Tumber A, Hatch SB, Zhang Y, Müller S, Chandler SA, Mair B, Li F, Nijman SMB, Konietzny R, Szommer T, Yapp C, Fedorov O, Benesch JLP, Vedadi M, Kessler BM, Kawamura A, Brennan PE, Smith MD.

Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15555-15559. doi: 10.1002/anie.201706788. Epub 2017 Nov 7.

3.

Superresolution microscopy of the β-carboxysome reveals a homogeneous matrix.

Niederhuber MJ, Lambert TJ, Yapp C, Silver PA, Polka JK.

Mol Biol Cell. 2017 Oct 1;28(20):2734-2745. doi: 10.1091/mbc.E17-01-0069. Epub 2017 Aug 9.

4.

Poly I:C Delivery into J774.1 and RAW264.7 Macrophages Induces Rapid Cell Death.

Yapp CW, Widaad Mohaimin A, Idris A.

Iran J Immunol. 2017 Sep;14(3):250-256. doi: IJIv14i3A8.

5.

Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation.

Meier JC, Tallant C, Fedorov O, Witwicka H, Hwang SY, van Stiphout RG, Lambert JP, Rogers C, Yapp C, Gerstenberger BS, Fedele V, Savitsky P, Heidenreich D, Daniels DL, Owen DR, Fish PV, Igoe NM, Bayle ED, Haendler B, Oppermann UCT, Buffa F, Brennan PE, Müller S, Gingras AC, Odgren PR, Birnbaum MJ, Knapp S.

ACS Chem Biol. 2017 Oct 20;12(10):2619-2630. doi: 10.1021/acschembio.7b00481. Epub 2017 Sep 12.

6.

Mesoporous Silica Nanoparticles as a Carrier Platform for Intracellular Delivery of Nucleic Acids.

Keasberry NA, Yapp CW, Idris A.

Biochemistry (Mosc). 2017 Jun;82(6):655-662. doi: 10.1134/S0006297917060025. Review.

7.

Highly selective inhibition of histone demethylases by de novo macrocyclic peptides.

Kawamura A, Münzel M, Kojima T, Yapp C, Bhushan B, Goto Y, Tumber A, Katoh T, King ON, Passioura T, Walport LJ, Hatch SB, Madden S, Müller S, Brennan PE, Chowdhury R, Hopkinson RJ, Suga H, Schofield CJ.

Nat Commun. 2017 Apr 6;8:14773. doi: 10.1038/ncomms14773.

8.

Assessing histone demethylase inhibitors in cells: lessons learned.

Hatch SB, Yapp C, Montenegro RC, Savitsky P, Gamble V, Tumber A, Ruda GF, Bavetsias V, Fedorov O, Atrash B, Raynaud F, Lanigan R, Carmichael L, Tomlin K, Burke R, Westaway SM, Brown JA, Prinjha RK, Martinez ED, Oppermann U, Schofield CJ, Bountra C, Kawamura A, Blagg J, Brennan PE, Rossanese O, Müller S.

Epigenetics Chromatin. 2017 Mar 1;10:9. doi: 10.1186/s13072-017-0116-6. eCollection 2017.

9.

HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus.

Fusco DN, Pratt H, Kandilas S, Cheon SS, Lin W, Cronkite DA, Basavappa M, Jeffrey KL, Anselmo A, Sadreyev R, Yapp C, Shi X, O'Sullivan JF, Gerszten RE, Tomaru T, Yoshino S, Satoh T, Chung RT.

Front Microbiol. 2017 Feb 20;8:240. doi: 10.3389/fmicb.2017.00240. eCollection 2017.

10.

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.

Tumber A, Nuzzi A, Hookway ES, Hatch SB, Velupillai S, Johansson C, Kawamura A, Savitsky P, Yapp C, Szykowska A, Wu N, Bountra C, Strain-Damerell C, Burgess-Brown NA, Ruda GF, Fedorov O, Munro S, England KS, Nowak RP, Schofield CJ, La Thangue NB, Pawlyn C, Davies F, Morgan G, Athanasou N, Müller S, Oppermann U, Brennan PE.

Cell Chem Biol. 2017 Mar 16;24(3):371-380. doi: 10.1016/j.chembiol.2017.02.006. Epub 2017 Mar 2.

11.

H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis.

Yapp C, Carr AJ, Price A, Oppermann U, Snelling SJ.

Arthritis Res Ther. 2016 Jul 7;18(1):158. doi: 10.1186/s13075-016-1053-7.

12.

Using Fluorescence Recovery After Photobleaching to Study Gap Junctional Communication In Vitro.

Kuzma-Kuzniarska M, Yapp C, Hulley PA.

Methods Mol Biol. 2016;1437:171-9. doi: 10.1007/978-1-4939-3664-9_12.

PMID:
27207294
13.

Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex.

Sutherell CL, Tallant C, Monteiro OP, Yapp C, Fuchs JE, Fedorov O, Siejka P, Müller S, Knapp S, Brenton JD, Brennan PE, Ley SV.

J Med Chem. 2016 May 26;59(10):5095-101. doi: 10.1021/acs.jmedchem.5b01997. Epub 2016 May 11.

14.

Frapid: achieving full automation of FRAP for chemical probe validation.

Yapp C, Rogers C, Savitsky P, Philpott M, Müller S.

Biomed Opt Express. 2016 Jan 11;7(2):422-41. doi: 10.1364/BOE.7.000422. eCollection 2016 Feb 1.

15.

The response of tenocytes to commercial scaffolds used for rotator cuff repair.

Smith RD, Carr A, Dakin SG, Snelling SJ, Yapp C, Hakimi O.

Eur Cell Mater. 2016 Jan 27;31:107-18.

16.

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.

Picaud S, Fedorov O, Thanasopoulou A, Leonards K, Jones K, Meier J, Olzscha H, Monteiro O, Martin S, Philpott M, Tumber A, Filippakopoulos P, Yapp C, Wells C, Che KH, Bannister A, Robson S, Kumar U, Parr N, Lee K, Lugo D, Jeffrey P, Taylor S, Vecellio ML, Bountra C, Brennan PE, O'Mahony A, Velichko S, Müller S, Hay D, Daniels DL, Urh M, La Thangue NB, Kouzarides T, Prinjha R, Schwaller J, Knapp S.

Cancer Res. 2015 Dec 1;75(23):5106-5119. doi: 10.1158/0008-5472.CAN-15-0236. Epub 2015 Nov 9.

17.

Inflammation activation and resolution in human tendon disease.

Dakin SG, Martinez FO, Yapp C, Wells G, Oppermann U, Dean BJ, Smith RD, Wheway K, Watkins B, Roche L, Carr AJ.

Sci Transl Med. 2015 Oct 28;7(311):311ra173. doi: 10.1126/scitranslmed.aac4269.

18.

Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases.

Thinnes CC, Tumber A, Yapp C, Scozzafava G, Yeh T, Chan MC, Tran TA, Hsu K, Tarhonskaya H, Walport LJ, Wilkins SE, Martinez ED, Müller S, Pugh CW, Ratcliffe PJ, Brennan PE, Kawamura A, Schofield CJ.

Chem Commun (Camb). 2015 Oct 28;51(84):15458-61. doi: 10.1039/c5cc06095h.

PMID:
26345662
19.

The Mechanical, Structural, and Compositional Changes of Tendon Exposed to Elastase.

Grant TM, Yapp C, Chen Q, Czernuszka JT, Thompson MS.

Ann Biomed Eng. 2015 Oct;43(10):2477-86. doi: 10.1007/s10439-015-1308-5. Epub 2015 Mar 26.

PMID:
25808209
20.

Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching.

Philpott M, Rogers CM, Yapp C, Wells C, Lambert JP, Strain-Damerell C, Burgess-Brown NA, Gingras AC, Knapp S, Müller S.

Epigenetics Chromatin. 2014 Jul 13;7:14. doi: 10.1186/1756-8935-7-14. eCollection 2014.

21.

Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains.

Hay DA, Fedorov O, Martin S, Singleton DC, Tallant C, Wells C, Picaud S, Philpott M, Monteiro OP, Rogers CM, Conway SJ, Rooney TP, Tumber A, Yapp C, Filippakopoulos P, Bunnage ME, Müller S, Knapp S, Schofield CJ, Brennan PE.

J Am Chem Soc. 2014 Jul 2;136(26):9308-19. doi: 10.1021/ja412434f. Epub 2014 Jun 19.

22.

Training doctors to respond to domestic violence: more than just communication skills.

Yapp CG.

BMJ. 2014 Mar 19;348:g2203. doi: 10.1136/bmj.g2203. No abstract available.

PMID:
24647173
23.

Functional assessment of gap junctions in monolayer and three-dimensional cultures of human tendon cells using fluorescence recovery after photobleaching.

Kuzma-Kuzniarska M, Yapp C, Pearson-Jones TW, Jones AK, Hulley PA.

J Biomed Opt. 2014 Jan;19(1):15001. doi: 10.1117/1.JBO.19.1.015001.

24.

Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.

Rotili D, Tomassi S, Conte M, Benedetti R, Tortorici M, Ciossani G, Valente S, Marrocco B, Labella D, Novellino E, Mattevi A, Altucci L, Tumber A, Yapp C, King ON, Hopkinson RJ, Kawamura A, Schofield CJ, Mai A.

J Med Chem. 2014 Jan 9;57(1):42-55. doi: 10.1021/jm4012802. Epub 2013 Dec 19.

PMID:
24325601
25.

[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains.

Fedorov O, Lingard H, Wells C, Monteiro OP, Picaud S, Keates T, Yapp C, Philpott M, Martin SJ, Felletar I, Marsden BD, Filippakopoulos P, Müller S, Knapp S, Brennan PE.

J Med Chem. 2014 Jan 23;57(2):462-76. doi: 10.1021/jm401568s. Epub 2013 Dec 30.

26.

5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation.

Hopkinson RJ, Tumber A, Yapp C, Chowdhury R, Aik W, Che KH, Li XS, Kristensen JBL, King ONF, Chan MC, Yeoh KK, Choi H, Walport LJ, Thinnes CC, Bush JT, Lejeune C, Rydzik AM, Rose NR, Bagg EA, McDonough MA, Krojer T, Yue WW, Ng SS, Olsen L, Brennan PE, Oppermann U, Muller-Knapp S, Klose RJ, Ratcliffe PJ, Schofield CJ, Kawamura A.

Chem Sci. 2013 Aug 1;4(8):3110-3117. doi: 10.1039/C3SC51122G.

27.

A novel in vitro loading system for high frequency loading of cultured tendon fascicles.

Adekanmbi I, Baboldashti NZ, Yapp C, Franklin S, Thompson MS.

Med Eng Phys. 2013 Feb;35(2):205-10. doi: 10.1016/j.medengphy.2012.08.015. Epub 2012 Sep 11. Erratum in: Med Eng Phys. 2013 Jul;35(7):1051. Baboldashti, Nasim Zargar [added]; Yapp, Clarence [added].

PMID:
22974534
28.

Hypertension management: a comparison of urban versus rural general practitioners in Western Australia.

Yapp CK, Taylor LS, Ow CY, Jamrozik K, Puddey IB.

Clin Exp Pharmacol Physiol. 1995 Jun-Jul;22(6-7):447-9.

PMID:
8582098
29.

Multiple isotope effect probes of glutamate decarboxylase.

O'Leary MH, Yamada H, Yapp CJ.

Biochemistry. 1981 Mar 17;20(6):1476-81.

PMID:
7013794
30.

Equilibrium carbon isotope effect on a decarboxylation reaction.

O'Leary MH, Yapp CJ.

Biochem Biophys Res Commun. 1978 Jan 13;80(1):155-60. No abstract available.

PMID:
623650
31.

Oxygen and hydrogen isotopic ratios in plant cellulose.

Epstein S, Thompson P, Yapp CJ.

Science. 1977 Dec 23;198(4323):1209-15.

PMID:
17741685
32.

Some Nurses' Problems.

Yapp CS.

Hospital (Lond 1886). 1919 Nov 15;67(1745):151. No abstract available.

33.

Certificated Nurses and Trades Unions: A Better and More Effective Alternative.

Yapp CS.

Hospital (Lond 1886). 1919 Oct 18;67(1741):61. No abstract available.

34.

Wake up, College of Nursing.

Yapp CS.

Hospital (Lond 1886). 1919 Jan 4;65(1700):287-288. No abstract available.

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