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4D modelling of fluid mechanics in the zebrafish embryonic heart.

Foo YY, Pant S, Tay HS, Imangali N, Chen N, Winkler C, Yap CH.

Biomech Model Mechanobiol. 2019 Aug 24. doi: 10.1007/s10237-019-01205-6. [Epub ahead of print]


Prevention is better than cure: Persian Gulf biodiversity vulnerability to the impacts of desalination plants.

Sharifinia M, Afshari Bahmanbeigloo Z, Smith WO Jr, Yap CK, Keshavarzifard M.

Glob Chang Biol. 2019 Aug 22. doi: 10.1111/gcb.14808. [Epub ahead of print]


When to keep it simple - adaptive designs are not always useful.

Wason JMS, Brocklehurst P, Yap C.

BMC Med. 2019 Aug 2;17(1):152. doi: 10.1186/s12916-019-1391-9.


Differences in placental capillary shear stress in fetal growth restriction may affect endothelial cell function and vascular network formation.

Tun WM, Yap CH, Saw SN, James JL, Clark AR.

Sci Rep. 2019 Jul 8;9(1):9876. doi: 10.1038/s41598-019-46151-6.


Risk Factors for Sedation-related Events During Acute Agitation Management in the Emergency Department.

Yap CYL, Taylor DM, Kong DCM, Knott JC, Taylor SE; Sedation for Acute Agitation in Emergency Department Patients: Targeting Adverse Events (SIESTA) Collaborative Study Group.

Acad Emerg Med. 2019 Jul 2. doi: 10.1111/acem.13826. [Epub ahead of print]


Optimizing Vancomycin Dosing in Chronic Kidney Disease by Deriving and Implementing a Web-Based Tool Using a Population Pharmacokinetics Analysis.

Dorajoo SR, Winata CL, Goh JHF, Ooi ST, Somani J, Yeoh LY, Lee SY, Yap CW, Chan A, Chae JW.

Front Pharmacol. 2019 Jun 11;10:641. doi: 10.3389/fphar.2019.00641. eCollection 2019.


Role of diastolic vortices in flow and energy dynamics during systolic ejection.

Vasudevan V, Low AJJ, Annamalai SP, Sampath S, Chin CL, Ali AAB, Yap CH.

J Biomech. 2019 Jun 11;90:50-57. doi: 10.1016/j.jbiomech.2019.04.026. Epub 2019 Apr 23.


Use of clinical quality indicators to improve lung cancer care in a regional/rural network of health services.

Kim ML, Matheson L, Garrard B, Francis M, Broad A, Malone J, Eastman P, Rogers M, Yap CH.

Aust J Rural Health. 2019 Apr;27(2):183-187. doi: 10.1111/ajr.12493. Epub 2019 Apr 4.


Nestin in immature embryonic neurons affects axon growth cone morphology and Semaphorin3a sensitivity.

Bott CJ, Johnson CG, Yap CC, Dwyer ND, Litwa KA, Winckler B.

Mol Biol Cell. 2019 May 1;30(10):1214-1229. doi: 10.1091/mbc.E18-06-0361. Epub 2019 Mar 6.


Fluid dynamics and forces in the HH25 avian embryonic outflow tract.

Ho S, Chan WX, Rajesh S, Phan-Thien N, Yap CH.

Biomech Model Mechanobiol. 2019 Aug;18(4):1123-1137. doi: 10.1007/s10237-019-01132-6. Epub 2019 Feb 27.


Illness Perception of Anxiety Patients in Primary Care in Singapore.

Yap CK, Wong MY, Lim KK.

Indian J Psychol Med. 2019 Jan-Feb;41(1):75-80. doi: 10.4103/IJPSYM.IJPSYM_101_18.


Targeting autophagy using natural compounds for cancer prevention and therapy.

Deng S, Shanmugam MK, Kumar AP, Yap CT, Sethi G, Bishayee A.

Cancer. 2019 Apr 15;125(8):1228-1246. doi: 10.1002/cncr.31978. Epub 2019 Feb 12. Review.


Hand dominance in traumatic shoulder dislocations.

Lim CR, Yap C, Campbell P.

JSES Open Access. 2018 May 22;2(2):137-140. doi: 10.1016/j.jses.2018.04.001. eCollection 2018 Jul.


How to design a dose-finding study using the continual reassessment method.

Wheeler GM, Mander AP, Bedding A, Brock K, Cornelius V, Grieve AP, Jaki T, Love SB, Odondi L, Weir CJ, Yap C, Bond SJ.

BMC Med Res Methodol. 2019 Jan 18;19(1):18. doi: 10.1186/s12874-018-0638-z.


Combination Lenalidomide and Azacitidine: A Novel Salvage Therapy in Patients Who Relapse After Allogeneic Stem-Cell Transplantation for Acute Myeloid Leukemia.

Craddock C, Slade D, De Santo C, Wheat R, Ferguson P, Hodgkinson A, Brock K, Cavenagh J, Ingram W, Dennis M, Malladi R, Siddique S, Mussai F, Yap C.

J Clin Oncol. 2019 Mar 1;37(7):580-588. doi: 10.1200/JCO.18.00889. Epub 2019 Jan 17.


SIAN: software for structural identifiability analysis of ODE models.

Hong H, Ovchinnikov A, Pogudin G, Yap C.

Bioinformatics. 2019 Aug 15;35(16):2873-2874. doi: 10.1093/bioinformatics/bty1069.


Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.

Yap CX, Sidorenko J, Wu Y, Kemper KE, Yang J, Wray NR, Robinson MR, Visscher PM.

Nat Commun. 2018 Dec 20;9(1):5407. doi: 10.1038/s41467-018-07862-y.


Effects of chronic diseases on health-related quality of life and self-rated health among three adult age groups.

Ge L, Ong R, Yap CW, Heng BH.

Nurs Health Sci. 2019 Jun;21(2):214-222. doi: 10.1111/nhs.12585. Epub 2018 Dec 10.


HIV knowledge, sexual health and sexual behaviour among Black and minority ethnic men who have sex with men in the UK: a cross-sectional study.

Jaspal R, Lopes B, Jamal Z, Yap C, Paccoud I, Sekhon P.

Sex Health. 2019 Feb;16(1):25-31. doi: 10.1071/SH18032.


Author Correction: Misestimation of heritability and prediction accuracy of male-pattern baldness.

Yap CX, Sidorenko J, Marioni RE, Yengo L, Wray NR, Visscher PM.

Nat Commun. 2018 Nov 20;9(1):4953. doi: 10.1038/s41467-018-07400-w.


Altered Placental Chorionic Arterial Biomechanical Properties During Intrauterine Growth Restriction.

Saw SN, Tay JJH, Poh YW, Yang L, Tan WC, Tan LK, Clark A, Biswas A, Mattar CNZ, Yap CH.

Sci Rep. 2018 Nov 8;8(1):16526. doi: 10.1038/s41598-018-34834-5.


A Mini Review: Can Graphene Be a Novel Material for Perovskite Solar Cell Applications?

Lim EL, Yap CC, Jumali MHH, Teridi MAM, Teh CH.

Nanomicro Lett. 2018;10(2):27. doi: 10.1007/s40820-017-0182-0. Epub 2017 Dec 22. Review.


Development of Clinical Criteria for Functional Assessment to Predict Primary Nonfunction of High-Risk Livers Using Normothermic Machine Perfusion.

Mergental H, Stephenson BTF, Laing RW, Kirkham AJ, Neil DAH, Wallace LL, Boteon YL, Widmer J, Bhogal RH, Perera MTPR, Smith A, Reynolds GM, Yap C, Hübscher SG, Mirza DF, Afford SC.

Liver Transpl. 2018 Oct;24(10):1453-1469. doi: 10.1002/lt.25291.


Bioinspired Dual-Tier Coalescence for Water-Collection Efficiency Enhancement.

Ang BTW, Yap CH, Vincent Lee WS, Xue J.

Langmuir. 2018 Nov 6;34(44):13409-13415. doi: 10.1021/acs.langmuir.8b02474. Epub 2018 Oct 26.


Deep sequencing of primary human lung epithelial cells challenged with H5N1 influenza virus reveals a proviral role for CEACAM1.

Ye S, Cowled CJ, Yap CH, Stambas J.

Sci Rep. 2018 Oct 19;8(1):15468. doi: 10.1038/s41598-018-33605-6.


A dominant dendrite phenotype caused by the disease-associated G253D mutation in doublecortin (DCX) is not due to its endocytosis defect.

Yap CC, Digilio L, Kruczek K, Roszkowska M, Fu XQ, Liu JS, Winckler B.

J Biol Chem. 2018 Dec 7;293(49):18890-18902. doi: 10.1074/jbc.RA118.004462. Epub 2018 Oct 5.


Naturopathic approaches to irritable bowel syndrome: protocol for a prospective observational study in academic teaching clinics.

Goldenberg JZ, Steel A, Day A, Yap C, Bradley R, Cooley K.

Integr Med Res. 2018 Sep;7(3):279-286. doi: 10.1016/j.imr.2018.06.001. Epub 2018 Jun 9.


Human fetal hearts with tetralogy of Fallot have altered fluid dynamics and forces.

Wiputra H, Chen CK, Talbi E, Lim GL, Soomar SM, Biswas A, Mattar CNZ, Bark D, Leo HL, Yap CH.

Am J Physiol Heart Circ Physiol. 2018 Dec 1;315(6):H1649-H1659. doi: 10.1152/ajpheart.00235.2018. Epub 2018 Sep 14.


The rate of progression of type 2 diabetes mellitus to end stage renal disease - A single centred retrospective study from Malaysia.

Ng YP, Ahmed R, Ooi GS, Lau CY, Balasubramanian GP, Yap CH.

Diabetes Metab Syndr. 2018 Nov;12(6):1025-1030. doi: 10.1016/j.dsx.2018.06.018. Epub 2018 Jul 5.


Iodine deficiency in women of childbearing age: not bread alone?

Burns K, Yap C, Mina A, Gunton JE.

Asia Pac J Clin Nutr. 2018;27(4):853-859. doi: 10.6133/apjcn.102017.02.


Author Correction: PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.

Wang L, Cho YL, Tang Y, Wang J, Park JE, Wu Y, Wang C, Tong Y, Chawla R, Zhang J, Shi Y, Deng S, Lu G, Wu Y, Tan HW, Pawijit P, Lim GG, Chan HY, Zhang J, Fang L, Yu H, Liou YC, Karthik M, Bay BH, Lim KL, Sze SK, Yap CT, Shen HM.

Cell Res. 2018 Aug;28(8):872-873. doi: 10.1038/s41422-018-0068-9.


Acute Macular Neuroretinopathy following Oral Intake of Adrenergic Flu Treatments.

Stanescu-Segall D, Yap C, Burton BJL.

Case Rep Ophthalmol. 2018 Jun 15;9(2):322-326. doi: 10.1159/000487075. eCollection 2018 May-Aug.


Effectiveness of the eCARE Programme: A Short Message Service (SMS) for Asthma Monitoring.

Prabhakaran L, Yap CW, Neo LP, Gan CC, Tham LM, Wong WM, Abisheganaden J, Lim TK.

Ann Acad Med Singapore. 2018 Jun;47(6):233-236. No abstract available.


The Real-World Cost-Effectiveness of Coronary Artery Bypass Surgery Versus Stenting in High-Risk Patients: Propensity Score-Matched Analysis of a Single-Centre Experience.

Ariyaratne TV, Ademi Z, Huq M, Rosenfeldt F, Duffy SJ, Parkinson B, Yap CH, Smith J, Billah B, Yan BP, Brennan AL, Tran L, Reid CM.

Appl Health Econ Health Policy. 2018 Oct;16(5):661-674. doi: 10.1007/s40258-018-0407-5.


Misestimation of heritability and prediction accuracy of male-pattern baldness.

Yap CX, Sidorenko J, Marioni RE, Yengo L, Wray NR, Visscher PM.

Nat Commun. 2018 Jun 29;9(1):2537. doi: 10.1038/s41467-018-04807-3. No abstract available. Erratum in: Nat Commun. 2018 Nov 20;9(1):4953.


PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.

Wang L, Cho YL, Tang Y, Wang J, Park JE, Wu Y, Wang C, Tong Y, Chawla R, Zhang J, Shi Y, Deng S, Lu G, Wu Y, Tan HW, Pawijit P, Lim GG, Chan HY, Zhang J, Fang L, Yu H, Liou YC, Karthik M, Bay BH, Lim KL, Sze SK, Yap CT, Shen HM.

Cell Res. 2018 Aug;28(8):787-802. doi: 10.1038/s41422-018-0056-0. Epub 2018 Jun 22. Erratum in: Cell Res. 2018 Jul 23;:.


Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes.

Yap CC, Digilio L, McMahon LP, Garcia ADR, Winckler B.

J Cell Biol. 2018 Sep 3;217(9):3141-3159. doi: 10.1083/jcb.201711039. Epub 2018 Jun 15.


Electrocatalytic proton reduction by an air-stable nickel(ii)-thiolato PNN pincer complex.

Yap CP, Chong YY, Chwee TS, Fan WY.

Dalton Trans. 2018 Jun 25;47(25):8483-8488. doi: 10.1039/c8dt00911b.


Trans-eQTLs identified in whole blood have limited influence on complex disease biology.

Yap CX, Lloyd-Jones L, Holloway A, Smartt P, Wray NR, Gratten J, Powell JE.

Eur J Hum Genet. 2018 Sep;26(9):1361-1368. doi: 10.1038/s41431-018-0174-7. Epub 2018 Jun 11.


Mesenchymal Stromal Cell (MSC)-Derived Combination of CXCL5 and Anti-CCL24 Is Synergistic and Superior to MSC and Cyclosporine for the Treatment of Graft-versus-Host Disease.

Fan X, Guo D, Cheung AMS, Poon ZY, Yap CS, Goh SE, Guo D, Li H, Bari S, Li S, Lim KH, Hwang WYK.

Biol Blood Marrow Transplant. 2018 Oct;24(10):1971-1980. doi: 10.1016/j.bbmt.2018.05.029. Epub 2018 Jun 5.


Results of a real-world study on vortioxetine in patients with major depressive disorder in South East Asia (REVIDA).

Chin CN, Zain A, Hemrungrojn S, Ung EK, Kwansanit P, Au Yong KC, Chong MSW, Inpa C, Yen TH, Yeoh BBD, Tay LK, Bernardo C, Lim LC, Yap CH, Fones C, Nayak A, Nelleman L.

Curr Med Res Opin. 2018 Nov;34(11):1975-1984. doi: 10.1080/03007995.2018.1477746. Epub 2018 Jun 14.


Sex differences in associations between multimorbidity and physical function domains among community-dwelling adults in Singapore.

Ge L, Yap CW, Heng BH.

PLoS One. 2018 May 14;13(5):e0197443. doi: 10.1371/journal.pone.0197443. eCollection 2018.


Characterization of the hemodynamic wall shear stresses in human umbilical vessels from normal and intrauterine growth restricted pregnancies.

Saw SN, Poh YW, Chia D, Biswas A, Mattar CNZ, Yap CH.

Biomech Model Mechanobiol. 2018 Aug;17(4):1107-1117. doi: 10.1007/s10237-018-1017-8. Epub 2018 Apr 24.


Signatures of negative selection in the genetic architecture of human complex traits.

Zeng J, de Vlaming R, Wu Y, Robinson MR, Lloyd-Jones LR, Yengo L, Yap CX, Xue A, Sidorenko J, McRae AF, Powell JE, Montgomery GW, Metspalu A, Esko T, Gibson G, Wray NR, Visscher PM, Yang J.

Nat Genet. 2018 May;50(5):746-753. doi: 10.1038/s41588-018-0101-4. Epub 2018 Apr 16.


Hyperelastic Mechanical Properties of Ex Vivo Normal and Intrauterine Growth Restricted Placenta.

Saw SN, Low JYR, Ong MHH, Poh YW, Mattar CNZ, Biswas A, Yap CH.

Ann Biomed Eng. 2018 Jul;46(7):1066-1077. doi: 10.1007/s10439-018-2019-5. Epub 2018 Apr 6.


Economic Evaluation of Midazolam-Droperidol Combination, Versus Droperidol or Olanzapine for the Management of Acute Agitation in the Emergency Department: A Within-Trial Analysis.

Yap CYL, Hsueh YA, Knott JC, Taylor DM, Chan EW, Kong DCM.

Pharmacoecon Open. 2018 Jun;2(2):141-151. doi: 10.1007/s41669-017-0047-y.


Transcytosis of TrkA leads to diversification of dendritic signaling endosomes.

Barford K, Keeler A, McMahon L, McDaniel K, Yap CC, Deppmann CD, Winckler B.

Sci Rep. 2018 Mar 16;8(1):4715. doi: 10.1038/s41598-018-23036-8.


Cognitive benefits of lithium chloride in APP/PS1 mice are associated with enhanced brain clearance of β-amyloid.

Pan Y, Short JL, Newman SA, Choy KHC, Tiwari D, Yap C, Senyschyn D, Banks WA, Nicolazzo JA.

Brain Behav Immun. 2018 May;70:36-47. doi: 10.1016/j.bbi.2018.03.007. Epub 2018 Mar 12.


Adaptive designs in clinical trials: why use them, and how to run and report them.

Pallmann P, Bedding AW, Choodari-Oskooei B, Dimairo M, Flight L, Hampson LV, Holmes J, Mander AP, Odondi L, Sydes MR, Villar SS, Wason JMS, Weir CJ, Wheeler GM, Yap C, Jaki T.

BMC Med. 2018 Feb 28;16(1):29. doi: 10.1186/s12916-018-1017-7.


Elevated Blood Viscosity and Microrecirculation Resulting From Coronary Stent Malapposition.

Poon EKW, Thondapu V, Hayat U, Barlis P, Yap CY, Kuo PH, Wang Q, Ma J, Zhu SJ, Moore S, Ooi ASH.

J Biomech Eng. 2018 May 1;140(5). doi: 10.1115/1.4039306.


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