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Items: 1 to 50 of 166

1.

Five Piconewtons: The Difference between Osteogenic and Adipogenic Fate Choice in Human Mesenchymal Stem Cells.

Han P, Frith JE, Gomez GA, Yap AS, O'Neill GM, Cooper-White JJ.

ACS Nano. 2019 Oct 9. doi: 10.1021/acsnano.9b03914. [Epub ahead of print]

PMID:
31580055
2.

Identification of intracellular cavin target proteins reveals cavin-PP1alpha interactions regulate apoptosis.

McMahon KA, Wu Y, Gambin Y, Sierecki E, Tillu VA, Hall T, Martel N, Okano S, Moradi SV, Ruelcke JE, Ferguson C, Yap AS, Alexandrov K, Hill MM, Parton RG.

Nat Commun. 2019 Jul 22;10(1):3279. doi: 10.1038/s41467-019-11111-1.

3.

The membrane environment of cadherin adhesion receptors: a working hypothesis.

Teo JL, Parton RG, Yap AS.

Biochem Soc Trans. 2019 Aug 30;47(4):985-995. doi: 10.1042/BST20180012. Epub 2019 Jul 5. Review.

PMID:
31278153
4.

Retraction: The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling.

Mansour M, Haupt S, Chan AL, Godde N, Rizzitelli A, Loi S, Caramia F, Deb S, Takano EA, Bishton M, Johnstone C, Monahan B, Levav-Cohen Y, Jiang YH, Yap AS, Fox S, Bernard O, Anderson R, Haupt Y.

Cancer Res. 2019 Jun 1;79(11):3008. doi: 10.1158/0008-5472.CAN-19-1133. No abstract available.

PMID:
31160311
5.

Anillin Promotes Cell Contractility by Cyclic Resetting of RhoA Residence Kinetics.

Budnar S, Husain KB, Gomez GA, Naghibosadat M, Varma A, Verma S, Hamilton NA, Morris RG, Yap AS.

Dev Cell. 2019 Jun 17;49(6):894-906.e12. doi: 10.1016/j.devcel.2019.04.031. Epub 2019 May 16.

PMID:
31105010
6.

Probing compression versus stretch activated recruitment of cortical actin and apical junction proteins using mechanical stimulations of suspended doublets.

Gao X, Acharya BR, Engl WCO, De Mets R, Thiery JP, Yap AS, Viasnoff V.

APL Bioeng. 2018 Jun 19;2(2):026111. doi: 10.1063/1.5025216. eCollection 2018 Jun.

7.

A Mechanosensitive RhoA Pathway that Protects Epithelia against Acute Tensile Stress.

Acharya BR, Nestor-Bergmann A, Liang X, Gupta S, Duszyc K, Gauquelin E, Gomez GA, Budnar S, Marcq P, Jensen OE, Bryant Z, Yap AS.

Dev Cell. 2018 Nov 19;47(4):439-452.e6. doi: 10.1016/j.devcel.2018.09.016. Epub 2018 Oct 11.

PMID:
30318244
8.

Tensile Forces and Mechanotransduction at Cell-Cell Junctions.

Charras G, Yap AS.

Curr Biol. 2018 Apr 23;28(8):R445-R457. doi: 10.1016/j.cub.2018.02.003. Review.

9.

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.

Boucher D, Monteleone M, Coll RC, Chen KW, Ross CM, Teo JL, Gomez GA, Holley CL, Bierschenk D, Stacey KJ, Yap AS, Bezbradica JS, Schroder K.

J Exp Med. 2018 Mar 5;215(3):827-840. doi: 10.1084/jem.20172222. Epub 2018 Feb 6.

10.

Notching a New Pathway in Vascular Flow Sensing.

Lagendijk AK, Yap AS, Hogan BM.

Trends Cell Biol. 2018 Mar;28(3):173-175. doi: 10.1016/j.tcb.2017.12.003. Epub 2018 Jan 2.

PMID:
29305160
11.

Author Correction: Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1.

Liang X, Budnar S, Gupta S, Verma S, Han SP, Hill MM, Daly RJ, Parton RG, Hamilton NA, Gomez GA, Yap AS.

Nat Commun. 2017 Dec 5;8(1):2021. doi: 10.1038/s41467-017-02131-w.

12.

Versatile Scaffold: Extrajunctional Roles for α-Catenin.

Budnar S, Yap AS.

Dev Cell. 2017 Nov 20;43(4):381-382. doi: 10.1016/j.devcel.2017.11.004. Review.

13.

Regulated recruitment of SRGAP1 modulates RhoA signaling for contractility during epithelial junction maturation.

Liang X, Kiru S, Gomez GA, Yap AS.

Cytoskeleton (Hoboken). 2018 Feb;75(2):61-69. doi: 10.1002/cm.21420. Epub 2017 Dec 5.

PMID:
29160905
14.

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish.

Lagendijk AK, Gomez GA, Baek S, Hesselson D, Hughes WE, Paterson S, Conway DE, Belting HG, Affolter M, Smith KA, Schwartz MA, Yap AS, Hogan BM.

Nat Commun. 2017 Nov 10;8(1):1402. doi: 10.1038/s41467-017-01325-6.

15.

Role of contact inhibition of locomotion and junctional mechanics in epithelial collective responses to injury.

Coburn L, Lopez H, Schouwenaar IM, Yap AS, Lobaskin V, Gomez GA.

Phys Biol. 2018 Jan 25;15(2):024001. doi: 10.1088/1478-3975/aa976b.

PMID:
29091048
16.

Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1.

Liang X, Budnar S, Gupta S, Verma S, Han SP, Hill MM, Daly RJ, Parton RG, Hamilton NA, Gomez GA, Yap AS.

Nat Commun. 2017 Oct 5;8(1):790. doi: 10.1038/s41467-017-00797-w. Erratum in: Nat Commun. 2017 Dec 5;8(1):2021.

17.

Mechanosensing and Mechanotransduction at Cell-Cell Junctions.

Yap AS, Duszyc K, Viasnoff V.

Cold Spring Harb Perspect Biol. 2018 Aug 1;10(8). pii: a028761. doi: 10.1101/cshperspect.a028761. Review.

PMID:
28778874
18.

In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis.

Duszyc K, Gomez GA, Schroder K, Sweet MJ, Yap AS.

Tissue Barriers. 2017 Oct 2;5(4):e1345353. doi: 10.1080/21688370.2017.1345353. Epub 2017 Jul 7. Review.

19.

Caveolae Protect Notochord Cells against Catastrophic Mechanical Failure during Development.

Lim YW, Lo HP, Ferguson C, Martel N, Giacomotto J, Gomez GA, Yap AS, Hall TE, Parton RG.

Curr Biol. 2017 Jul 10;27(13):1968-1981.e7. doi: 10.1016/j.cub.2017.05.067. Epub 2017 Jun 22.

20.

Mammalian Diaphanous 1 Mediates a Pathway for E-cadherin to Stabilize Epithelial Barriers through Junctional Contractility.

Acharya BR, Wu SK, Lieu ZZ, Parton RG, Grill SW, Bershadsky AD, Gomez GA, Yap AS.

Cell Rep. 2017 Mar 21;18(12):2854-2867. doi: 10.1016/j.celrep.2017.02.078.

21.

Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis.

Kerr MC, Gomez GA, Ferguson C, Tanzer MC, Murphy JM, Yap AS, Parton RG, Huston WM, Teasdale RD.

Nat Commun. 2017 Mar 10;8:14729. doi: 10.1038/ncomms14729.

22.

Bistable front dynamics in a contractile medium: Travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions.

Priya R, Gomez GA, Budnar S, Acharya BR, Czirok A, Yap AS, Neufeld Z.

PLoS Comput Biol. 2017 Mar 8;13(3):e1005411. doi: 10.1371/journal.pcbi.1005411. eCollection 2017 Mar.

23.

Tmem2 Regulates Embryonic Vegf Signaling by Controlling Hyaluronic Acid Turnover.

De Angelis JE, Lagendijk AK, Chen H, Tromp A, Bower NI, Tunny KA, Brooks AJ, Bakkers J, Francois M, Yap AS, Simons C, Wicking C, Hogan BM, Smith KA.

Dev Cell. 2017 Feb 27;40(4):421. doi: 10.1016/j.devcel.2017.02.005. No abstract available.

24.

Tmem2 Regulates Embryonic Vegf Signaling by Controlling Hyaluronic Acid Turnover.

De Angelis JE, Lagendijk AK, Chen H, Tromp A, Bower NI, Tunny KA, Brooks AJ, Bakkers J, Francois M, Yap AS, Simons C, Wicking C, Hogan BM, Smith KA.

Dev Cell. 2017 Jan 23;40(2):123-136. doi: 10.1016/j.devcel.2016.12.017.

25.

ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens.

Priya R, Liang X, Teo JL, Duszyc K, Yap AS, Gomez GA.

Mol Biol Cell. 2017 Jan 1;28(1):12-20. doi: 10.1091/mbc.E16-04-0262. Epub 2016 Nov 9.

26.

Editorial overview: Membrane traffic and cell polarity.

Bryant DM, Yap AS.

Traffic. 2016 Dec;17(12):1231-1232. doi: 10.1111/tra.12433. No abstract available.

27.

Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates.

Coburn L, Lopez H, Caldwell BJ, Moussa E, Yap C, Priya R, Noppe A, Roberts AP, Lobaskin V, Yap AS, Neufeld Z, Gomez GA.

Mol Biol Cell. 2016 Nov 7;27(22):3436-3448. Epub 2016 Sep 7.

28.

Targeted Genome Editing via CRISPR in the Pathogen Cryptococcus neoformans.

Arras SD, Chua SM, Wizrah MS, Faint JA, Yap AS, Fraser JA.

PLoS One. 2016 Oct 6;11(10):e0164322. doi: 10.1371/journal.pone.0164322. eCollection 2016.

29.

Coronin 1B supports RhoA signaling at cell-cell junctions through Myosin II.

Priya R, Wee K, Budnar S, Gomez GA, Yap AS, Michael M.

Cell Cycle. 2016 Nov 16;15(22):3033-3041. Epub 2016 Sep 20.

30.

Cycling Rho for tissue contraction.

Teo JL, Yap AS.

J Cell Biol. 2016 Aug 29;214(5):495-8. doi: 10.1083/jcb.201608017. Epub 2016 Aug 22.

31.

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling.

Humphrey ES, Su SP, Nagrial AM, Hochgräfe F, Pajic M, Lehrbach GM, Parton RG, Yap AS, Horvath LG, Chang DK, Biankin AV, Wu J, Daly RJ.

Mol Cell Proteomics. 2016 Aug;15(8):2671-85. doi: 10.1074/mcp.M116.058313. Epub 2016 Jun 3.

32.

The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling.

Mansour M, Haupt S, Chan AL, Godde N, Rizzitelli A, Loi S, Caramia F, Deb S, Takano EA, Bishton M, Johnstone C, Monahan B, Levav-Cohen Y, Jiang YH, Yap AS, Fox S, Bernard O, Anderson R, Haupt Y.

Cancer Res. 2016 Jul 15;76(14):4236-48. doi: 10.1158/0008-5472.CAN-15-1553. Epub 2016 May 26. Retraction in: Cancer Res. 2019 Jun 1;79(11):3008.

33.

The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis.

Oh TG, Wang SM, Acharya BR, Goode JM, Graham JD, Clarke CL, Yap AS, Muscat GEO.

EBioMedicine. 2016 Apr;6:59-72. doi: 10.1016/j.ebiom.2016.02.028. Epub 2016 Feb 18.

34.

Remodeling the zonula adherens in response to tension and the role of afadin in this response.

Choi W, Acharya BR, Peyret G, Fardin MA, Mège RM, Ladoux B, Yap AS, Fanning AS, Peifer M.

J Cell Biol. 2016 Apr 25;213(2):243-60. doi: 10.1083/jcb.201506115.

35.

Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions.

Michael M, Meiring JCM, Acharya BR, Matthews DR, Verma S, Han SP, Hill MM, Parton RG, Gomez GA, Yap AS.

Dev Cell. 2016 Apr 4;37(1):58-71. doi: 10.1016/j.devcel.2016.03.008.

36.

Neogenin recruitment of the WAVE regulatory complex maintains adherens junction stability and tension.

Lee NK, Fok KW, White A, Wilson NH, O'Leary CJ, Cox HL, Michael M, Yap AS, Cooper HM.

Nat Commun. 2016 Mar 31;7:11082. doi: 10.1038/ncomms11082.

37.

Pli Selon Pli: Mechanochemical Feedback and the Morphogenetic Role of Contractility at Cadherin Cell-Cell Junctions.

Acharya BR, Yap AS.

Curr Top Dev Biol. 2016;117:631-46. doi: 10.1016/bs.ctdb.2015.10.021. Epub 2016 Jan 7. Review.

PMID:
26970005
38.

Biomechanical guidance helps elongate a lumen.

Wee K, Yap AS.

Nat Cell Biol. 2016 Mar;18(3):255-7. doi: 10.1038/ncb3319.

PMID:
26911909
39.

Vegfc Regulates Bipotential Precursor Division and Prox1 Expression to Promote Lymphatic Identity in Zebrafish.

Koltowska K, Lagendijk AK, Pichol-Thievend C, Fischer JC, Francois M, Ober EA, Yap AS, Hogan BM.

Cell Rep. 2015 Dec 1;13(9):1828-41. doi: 10.1016/j.celrep.2015.10.055. Epub 2015 Nov 19.

40.

Mammalian farnesyltransferase α subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A)--dependent intracellular trafficking through recycling endosomes.

Kubala MH, Norwood SJ, Gomez GA, Jones A, Johnston W, Yap AS, Mureev S, Alexandrov K.

Biochem Biophys Res Commun. 2015 Dec 25;468(4):580-6. doi: 10.1016/j.bbrc.2015.10.148. Epub 2015 Nov 10.

PMID:
26551458
41.

Seeing and believing: recent advances in imaging cell-cell interactions.

Yap AS, Michael M, Parton RG.

F1000Res. 2015 Jul 17;4(F1000 Faculty Rev):273. doi: 10.12688/f1000research.6435.1. eCollection 2015. Review.

42.

Towards a Dynamic Understanding of Cadherin-Based Mechanobiology.

Hoffman BD, Yap AS.

Trends Cell Biol. 2015 Dec;25(12):803-814. doi: 10.1016/j.tcb.2015.09.008. Epub 2015 Oct 28. Review.

PMID:
26519989
43.

Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies.

Yap AS, Gomez GA, Parton RG.

Dev Cell. 2015 Oct 12;35(1):12-20. doi: 10.1016/j.devcel.2015.09.012. Review.

44.

Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions.

Priya R, Gomez GA, Budnar S, Verma S, Cox HL, Hamilton NA, Yap AS.

Nat Cell Biol. 2015 Oct;17(10):1282-93. doi: 10.1038/ncb3239. Epub 2015 Sep 14.

PMID:
26368311
45.

Making a Choice: How Cadherin Switching Controls Cell Migration.

Priya R, Yap AS.

Dev Cell. 2015 Aug 24;34(4):383-4. doi: 10.1016/j.devcel.2015.08.002.

46.

Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization.

Greenlees R, Mihelec M, Yousoof S, Speidel D, Wu SK, Rinkwitz S, Prokudin I, Perveen R, Cheng A, Ma A, Nash B, Gillespie R, Loebel DA, Clayton-Smith J, Lloyd IC, Grigg JR, Tam PP, Yap AS, Becker TS, Black GC, Semina E, Jamieson RV.

Hum Mol Genet. 2015 Oct 15;24(20):5789-804. doi: 10.1093/hmg/ddv298. Epub 2015 Jul 30.

PMID:
26231217
47.

Modelling wound closure in an epithelial cell sheet using the cellular Potts model.

Noppe AR, Roberts AP, Yap AS, Gomez GA, Neufeld Z.

Integr Biol (Camb). 2015 Oct;7(10):1253-64. doi: 10.1039/c5ib00053j. Epub 2015 Jun 29.

PMID:
26119963
48.

E-cadherin junctions as active mechanical integrators in tissue dynamics.

Lecuit T, Yap AS.

Nat Cell Biol. 2015 May;17(5):533-9. doi: 10.1038/ncb3136. Review.

PMID:
25925582
49.

Preface. Cellular adhesion in development and disease.

Yap AS.

Curr Top Dev Biol. 2015;112:xv-xvii. doi: 10.1016/S0070-2153(15)00024-1. No abstract available.

PMID:
25733150
50.

Active tension: the role of cadherin adhesion and signaling in generating junctional contractility.

Priya R, Yap AS.

Curr Top Dev Biol. 2015;112:65-102. doi: 10.1016/bs.ctdb.2014.11.016. Epub 2015 Feb 12. Review.

PMID:
25733138

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