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Previous Aphid Infestation Induces Different Expression Profiles of Genes Associated with Hormone-Dependent Responses in Near-Isogenic Winter Wheat Lines.

Luo K, Yao XJ, Luo C, Hu XS, Hu ZQ, Zhang GS, Zhao HY.

J Econ Entomol. 2020 Feb 8;113(1):461-470. doi: 10.1093/jee/toz222.


miR‑20b promotes growth of non‑small cell lung cancer through a positive feedback loop of the Wnt/β‑catenin signaling pathway.

Ren T, Fan XX, Wang MF, Duan FG, Wei CL, Li RZ, Jiang ZB, Wang YW, Yao XJ, Chen MW, Tang YJ, Leung EL.

Int J Oncol. 2020 Feb;56(2):470-479. doi: 10.3892/ijo.2019.4940. Epub 2019 Dec 13.


Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism.

Law BYK, Michelangeli F, Qu YQ, Xu SW, Han Y, Mok SWF, Dias IRSR, Javed MU, Chan WK, Xue WW, Yao XJ, Zeng W, Zhang H, Wang JR, Liu L, Wong VKW.

Sci Rep. 2019 Dec 27;9(1):20034. doi: 10.1038/s41598-019-56675-6.


Investigator-initiated clinical study of a functional peptide, SR-0379, for limb ulcers of patients with Werner syndrome as a pilot study.

Nakagami H, Sugimoto K, Ishikawa T, Koshizaka M, Fujimoto T, Kiyohara E, Hayashi M, Nakagawa Y, Ando H, Terabe Y, Takami Y, Yamamoto K, Takeya Y, Takemoto M, Ebihara T, Nakamura A, Nishikawa M, Yao XJ, Hanaoka H, Yokote K, Rakugi H.

Geriatr Gerontol Int. 2019 Nov;19(11):1118-1123. doi: 10.1111/ggi.13782.


Wortmannine H, a phenylpentenol isolated from an endophytic fungus, Talaromyces wortmannii LGT-4.

Li XF, Yang ZD, Yang X, Yang LJ, Yao XJ, Shu ZM.

Nat Prod Res. 2019 Nov 12:1-6. doi: 10.1080/14786419.2019.1690488. [Epub ahead of print]


MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3'UTR and predicts poor survival in non-small cell lung cancer.

Duan FG, Wang MF, Cao YB, Dan Li, Li RZ, Fan XX, Khan I, Lai HL, Zhang YZ, Hsiao WW, Yao XJ, Wu QB, Liu L, Tang YJ, Leung EL.

Cell Death Dis. 2019 Oct 28;10(11):821. doi: 10.1038/s41419-019-2031-1.


Long-term in vivo study of biodegradable Zn-Cu stent: A 2-year implantation evaluation in porcine coronary artery.

Zhou C, Li HF, Yin YX, Shi ZZ, Li T, Feng XY, Zhang JW, Song CX, Cui XS, Xu KL, Zhao YW, Hou WB, Lu ST, Liu G, Li MQ, Ma JY, Toft E, Volinsky AA, Wan M, Yao XJ, Wang CB, Yao K, Xu SK, Lu H, Chang SF, Ge JB, Wang LN, Zhang HJ.

Acta Biomater. 2019 Oct 1;97:657-670. doi: 10.1016/j.actbio.2019.08.012. Epub 2019 Aug 8.


p53 sensitizes chemoresistant non-small cell lung cancer via elevation of reactive oxygen species and suppression of EGFR/PI3K/AKT signaling.

Zhang Y, Han CY, Duan FG, Fan XX, Yao XJ, Parks RJ, Tang YJ, Wang MF, Liu L, Tsang BK, Leung EL.

Cancer Cell Int. 2019 Jul 19;19:188. doi: 10.1186/s12935-019-0910-2. eCollection 2019.


Aggreganoids A-F, Carbon-Bridged Sesquiterpenoid Dimers and Trimers from Lindera aggregata.

Liu X, Yang J, Fu J, Yao XJ, Wang JR, Liu L, Jiang ZH, Zhu GY.

Org Lett. 2019 Jul 19;21(14):5753-5756. doi: 10.1021/acs.orglett.9b02166. Epub 2019 Jul 5.


Linderalides A-D, Disesquiterpenoid-Geranylbenzofuranone Conjugates from Lindera aggregata.

Liu X, Yang J, Yao XJ, Yang X, Fu J, Bai LP, Liu L, Jiang ZH, Zhu GY.

J Org Chem. 2019 Jun 21;84(12):8242-8247. doi: 10.1021/acs.joc.9b00522. Epub 2019 Jun 10.


Intracranial Mirror Aneurysm: Epidemiology, Rupture Risk, New Imaging, Controversies, and Treatment Strategies.

Liu HJ, Zhou H, Lu DL, Jiao YB, Chen SF, Cheng J, Yao XJ, Ren JY, Li SF, Liu W, Gao JC, Yue Y, Xu JX, Zhang PN, Feng YG.

World Neurosurg. 2019 Jul;127:165-175. doi: 10.1016/j.wneu.2019.03.275. Epub 2019 Apr 4. Review.


Two new compounds, Talaromycin A and B, isolated from an endophytic fungus, Talaromyces aurantiacus.

Zhang YF, Yang ZD, Yang X, Yang LJ, Yao XJ, Shu ZM.

Nat Prod Res. 2019 Mar 31:1-7. doi: 10.1080/14786419.2019.1593163. [Epub ahead of print]


Phenolic acids and their glycosides from the rhizomes of Cimicifuga dahurica.

Lu Q, Zhang WY, Pan DB, Shi DF, Pang QQ, Li HB, Yao XJ, Yao ZH, Yu Y, Yao XS.

Fitoterapia. 2019 Apr;134:485-492. doi: 10.1016/j.fitote.2019.03.023. Epub 2019 Mar 23.


Near-Complete Genome Sequences of 12 Coxsackievirus Group A Strains from Hand, Foot, and Mouth Disease and Herpangina Cases with Different Clinical Symptoms.

Xu SJ, He YQ, Zhang RL, Yang H, Yao XJ, Zhang HL, Meng J, Chen L, Lin QH.

Microbiol Resour Announc. 2019 Feb 21;8(8). pii: e01655-18. doi: 10.1128/MRA.01655-18. eCollection 2019 Feb.


Structure based virtual screening of novel noncompetitive antagonist  of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor.

Duan ML, Tan LL, Du J, Yao XJ.

J Biotechnol. 2019 Apr 10;295:9-18. doi: 10.1016/j.jbiotec.2019.01.023. Epub 2019 Mar 1.


Identification of a new inhibitor of KRAS-PDEδ interaction targeting KRAS mutant nonsmall cell lung cancer.

Leung EL, Luo LX, Li Y, Liu ZQ, Li LL, Shi DF, Xie Y, Huang M, Lu LL, Duan FG, Huang JM, Fan XX, Yuan ZW, Ding J, Yao XJ, Ward DC, Liu L.

Int J Cancer. 2019 Sep 1;145(5):1334-1345. doi: 10.1002/ijc.32222. Epub 2019 Mar 12.


How Does Chirality Determine the Selective Inhibition of Histone Deacetylase 6? A Lesson from Trichostatin A Enantiomers Based on Molecular Dynamics.

Zhang Y, Ying JB, Hong JJ, Li FC, Fu TT, Yang FY, Zheng GX, Yao XJ, Lou Y, Qiu Y, Xue WW, Zhu F.

ACS Chem Neurosci. 2019 May 15;10(5):2467-2480. doi: 10.1021/acschemneuro.8b00729. Epub 2019 Feb 26.


Molecular surveillance of coxsackievirus A16 reveals the emergence of a new clade in mainland China.

Chen L, Yao XJ, Xu SJ, Yang H, Wu CL, Lu J, Xu WB, Zhang HL, Meng J, Zhang Y, He YQ, Zhang RL.

Arch Virol. 2019 Mar;164(3):867-874. doi: 10.1007/s00705-018-4112-3. Epub 2018 Nov 29.


What Roles Do Probiotics Play in the Eradication of Helicobacter pylori? Current Knowledge and Ongoing Research.

Song HY, Zhou L, Liu DY, Yao XJ, Li Y.

Gastroenterol Res Pract. 2018 Oct 16;2018:9379480. doi: 10.1155/2018/9379480. eCollection 2018. Review.


Binding Performance of Human Intravenous Immunoglobulin and 20(S)-7-Ethylcamptothecin.

Liu YC, Li YY, Yao XJ, Qi HL, Wei XX, Liu JN.

Molecules. 2018 Sep 18;23(9). pii: E2389. doi: 10.3390/molecules23092389.


Identification of a potent kinase inhibitor targeting EML4-ALK fusion protein in non-small cell lung cancer.

Luo LX, Li Y, Niu YZ, Wang YW, Wang QQ, Fan XX, Xu JH, Liu L, Leung EL, Yao XJ.

Medchemcomm. 2017 Aug 25;8(10):1914-1918. doi: 10.1039/c7md00305f. eCollection 2017 Oct 1.


Potential Role of Interleukin-25/Interleukin-33/Thymic Stromal Lymphopoietin-Fibrocyte Axis in the Pathogenesis of Allergic Airway Diseases.

Yao XJ, Liu XF, Wang XD.

Chin Med J (Engl). 2018 Aug 20;131(16):1983-1989. doi: 10.4103/0366-6999.238150. Review.


Identification of a new pyruvate kinase M2 isoform (PKM2) activator for the treatment of non-small-cell lung cancer (NSCLC).

Li RZ, Fan XX, Shi DF, Zhu GY, Wang YW, Luo LX, Pan HD, Yao XJ, Leung EL, Liu L.

Chem Biol Drug Des. 2018 Nov;92(5):1851-1858. doi: 10.1111/cbdd.13354. Epub 2018 Jul 10.


Psoriasis localized to the glans penis in a 37-year-old man.

Yao XJ, Zhang TD.

CMAJ. 2018 Jun 18;190(24):E747. doi: 10.1503/cmaj.180262. No abstract available.


Proscillaridin A induces apoptosis and suppresses non-small-cell lung cancer tumor growth via calcium-induced DR4 upregulation.

Li RZ, Fan XX, Duan FG, Jiang ZB, Pan HD, Luo LX, Zhou YL, Li Y, Yao YJ, Yao XJ, Leung EL, Liu L.

Cell Death Dis. 2018 Jun 13;9(6):696. doi: 10.1038/s41419-018-0733-4.


Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells.

Dai X, Li RZ, Jiang ZB, Wei CL, Luo LX, Yao XJ, Li GP, Leung EL.

Front Pharmacol. 2018 May 28;9:558. doi: 10.3389/fphar.2018.00558. eCollection 2018.


Phenolic Constituents Isolated from the Twigs of Cinnamomum cassia and Their Potential Neuroprotective Effects.

Liu X, Fu J, Yao XJ, Yang J, Liu L, Xie TG, Jiang PC, Jiang ZH, Zhu GY.

J Nat Prod. 2018 Jun 22;81(6):1333-1342. doi: 10.1021/acs.jnatprod.7b00924. Epub 2018 Jun 8.


Comparison of the degradation behavior of PLGA scaffolds in micro-channel, shaking, and static conditions.

Ma CH, Zhang HB, Yang SM, Yin RX, Yao XJ, Zhang WJ.

Biomicrofluidics. 2018 May 18;12(3):034106. doi: 10.1063/1.5021394. eCollection 2018 May.


Complete Genome Sequence of an Enterovirus A71 Strain Isolated in 2006 from a Patient in Shenzhen, Southern China, with a Lethal Case of Enterovirus Infection.

Yao XJ, Chen L, Yang H, Meng J, Zhang HL, Jiang M, Zhang HY, He YQ, Wu CL, Zhang RL.

Genome Announc. 2018 Mar 8;6(10). pii: e00074-18. doi: 10.1128/genomeA.00074-18.


Physician-initiated clinical study of limb ulcers treated with a functional peptide, SR-0379: from discovery to a randomized, double-blind, placebo-controlled trial.

Nakagami H, Sugimoto K, Ishikawa T, Fujimoto T, Yamaoka T, Hayashi M, Kiyohara E, Ando H, Terabe Y, Takami Y, Yamamoto K, Takeya Y, Takemoto M, Koshizaka M, Ebihara T, Nakamura A, Nishikawa M, Yao XJ, Hanaoka H, Katayama I, Yokote K, Rakugi H.

NPJ Aging Mech Dis. 2018 Feb 13;4:2. doi: 10.1038/s41514-018-0021-7. eCollection 2018.


Inhibition of KRAS-dependent lung cancer cell growth by deltarasin: blockage of autophagy increases its cytotoxicity.

Leung ELH, Luo LX, Liu ZQ, Wong VKW, Lu LL, Xie Y, Zhang N, Qu YQ, Fan XX, Li Y, Huang M, Xiao DK, Huang J, Zhou YL, He JX, Ding J, Yao XJ, Ward DC, Liu L.

Cell Death Dis. 2018 Feb 13;9(2):216. doi: 10.1038/s41419-017-0065-9.


(±)-Sativamides A and B, Two Pairs of Racemic Nor-Lignanamide Enantiomers from the Fruits of Cannabis sativa.

Zhu GY, Yang J, Yao XJ, Yang X, Fu J, Liu X, Bai LP, Liu L, Jiang ZH.

J Org Chem. 2018 Feb 16;83(4):2376-2381. doi: 10.1021/acs.joc.7b02765. Epub 2018 Jan 31.


Dimeric Cadinane Sesquiterpenoid Derivatives from Artemisia annua.

Qin DP, Pan DB, Xiao W, Li HB, Yang B, Yao XJ, Dai Y, Yu Y, Yao XS.

Org Lett. 2018 Jan 19;20(2):453-456. doi: 10.1021/acs.orglett.7b03796. Epub 2018 Jan 4.


Descriptor Selection via Log-Sum Regularization for the Biological Activities of Chemical Structure.

Xia LY, Wang YW, Meng DY, Yao XJ, Chai H, Liang Y.

Int J Mol Sci. 2017 Dec 22;19(1). pii: E30. doi: 10.3390/ijms19010030.


Novel direct AMPK activator suppresses non-small cell lung cancer through inhibition of lipid metabolism.

Chen X, Xie C, Fan XX, Jiang ZB, Wong VK, Xu JH, Yao XJ, Liu L, Leung EL.

Oncotarget. 2017 Oct 9;8(56):96089-96102. doi: 10.18632/oncotarget.21716. eCollection 2017 Nov 10.


Identification of a New Potent Inhibitor Targeting KRAS in Non-small Cell Lung Cancer Cells.

Xie C, Li Y, Li LL, Fan XX, Wang YW, Wei CL, Liu L, Leung EL, Yao XJ.

Front Pharmacol. 2017 Nov 14;8:823. doi: 10.3389/fphar.2017.00823. eCollection 2017.


[Association of PD-1, TIM-3 and TREM-1 single nucleotide polymorphisms with pulmonary tuberculosis susceptibility].

Wang FM, Zhang X, Lan L, Ji JM, Tang HB, Yao XJ, Jiang Y, Qian J, Xu XG, Li Q, Yao P, Li JH, Shen YP.

Zhonghua Yi Xue Za Zhi. 2017 Nov 14;97(42):3301-3305. doi: 10.3760/cma.j.issn.0376-2491.2017.42.006. Chinese.


Complete Genome Sequences of Four Coxsackievirus A16 Strains Isolated from Four Children with Severe Hand, Foot, and Mouth Disease.

Xu SJ, Yang H, Yao XJ, Zhang HL, Ren Y, Wu W, Meng J, Chen HB, He YQ, Zhang RL, Lin QH, Chen L.

Genome Announc. 2017 Aug 3;5(31). pii: e00760-17. doi: 10.1128/genomeA.00760-17.


Suppressing mPGES-1 expression by sinomenine ameliorates inflammation and arthritis.

Zhou H, Liu JX, Luo JF, Cheng CS, Leung EL, Li Y, Su XH, Liu ZQ, Chen TB, Duan FG, Dong Y, Zuo YH, Li C, Lio CK, Li T, Luo P, Xie Y, Yao XJ, Wang PX, Liu L.

Biochem Pharmacol. 2017 Oct 15;142:133-144. doi: 10.1016/j.bcp.2017.07.010. Epub 2017 Jul 13.


N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca2+ Mobilization.

Law BYK, Mok SWF, Chen J, Michelangeli F, Jiang ZH, Han Y, Qu YQ, Qiu ACL, Xu SW, Xue WW, Yao XJ, Gao JY, Javed MU, Coghi P, Liu L, Wong VKW.

Front Pharmacol. 2017 Jun 16;8:388. doi: 10.3389/fphar.2017.00388. eCollection 2017.


Suppression of Lipogenesis via Reactive Oxygen Species-AMPK Signaling for Treating Malignant and Proliferative Diseases.

Fan XX, Leung EL, Xie Y, Liu ZQ, Zheng YF, Yao XJ, Lu LL, Wu JL, He JX, Yuan ZW, Fu J, Wei CL, Huang J, Xiao DK, Luo LX, Jiang ZB, Zhou YL, Kam RK, Liu L.

Antioxid Redox Signal. 2018 Feb 10;28(5):339-357. doi: 10.1089/ars.2017.7090. Epub 2017 Aug 4. Erratum in: Antioxid Redox Signal. 2019 Feb 1;30(4):710.


Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms.

Wong VKW, Zeng W, Chen J, Yao XJ, Leung ELH, Wang QQ, Chiu P, Ko BCB, Law BYK.

Front Pharmacol. 2017 Jun 8;8:351. doi: 10.3389/fphar.2017.00351. eCollection 2017.


Identification of Epigallocatechin-3- Gallate as an Inhibitor of Phosphoglycerate Mutase 1.

Li X, Tang S, Wang QQ, Leung EL, Jin H, Huang Y, Liu J, Geng M, Huang M, Yuan S, Yao XJ, Ding J.

Front Pharmacol. 2017 May 30;8:325. doi: 10.3389/fphar.2017.00325. eCollection 2017.


DNA vaccination protects mice against Zika virus-induced damage to the testes.

Griffin BD, Muthumani K, Warner BM, Majer A, Hagan M, Audet J, Stein DR, Ranadheera C, Racine T, De La Vega MA, Piret J, Kucas S, Tran KN, Frost KL, De Graff C, Soule G, Scharikow L, Scott J, McTavish G, Smid V, Park YK, Maslow JN, Sardesai NY, Kim JJ, Yao XJ, Bello A, Lindsay R, Boivin G, Booth SA, Kobasa D, Embury-Hyatt C, Safronetz D, Weiner DB, Kobinger GP.

Nat Commun. 2017 Jun 7;8:15743. doi: 10.1038/ncomms15743.


[Application of long term video electroencephalogram and resting-state functional magnetic resonance imaging in detection of cognition in patients with benign epilepsy of childhood with centrotemporal spikes].

Yan XX, Yu Q, Gao YT, Li LT, Yu DH, Chen Y, Yao XJ, Yang WD, Chen ZJ, Yin JZ, An Y, Tan K.

Zhonghua Yi Xue Za Zhi. 2017 May 23;97(19):1474-1478. doi: 10.3760/cma.j.issn.0376-2491.2017.19.010. Chinese.


Honokiol Induces Apoptosis, G1 Arrest, and Autophagy in KRAS Mutant Lung Cancer Cells.

Luo LX, Li Y, Liu ZQ, Fan XX, Duan FG, Li RZ, Yao XJ, Leung EL, Liu L.

Front Pharmacol. 2017 Apr 11;8:199. doi: 10.3389/fphar.2017.00199. eCollection 2017.


Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death.

Law BYK, Gordillo-Martínez F, Qu YQ, Zhang N, Xu SW, Coghi PS, Mok SWF, Guo J, Zhang W, Leung ELH, Fan XX, Wu AG, Chan WK, Yao XJ, Wang JR, Liu L, Wong VKW.

Oncotarget. 2017 May 2;8(18):30077-30091. doi: 10.18632/oncotarget.15616.


Molecular basis of P450 OleTJE: an investigation of substrate binding mechanism and major pathways.

Du J, Liu L, Guo LZ, Yao XJ, Yang JM.

J Comput Aided Mol Des. 2017 May;31(5):483-495. doi: 10.1007/s10822-017-0013-x. Epub 2017 Mar 25.


Inhibition of Monoamine Oxidase by Stilbenes from Rheum palmatum.

Wei B, Yang ZD, Shi DF, Yao XJ, Wang MG.

Iran J Pharm Res. 2016 Fall;15(4):885-892.


In Situ Bioorthogonal Metabolic Labeling for Fluorescence Imaging of Virus Infection In Vivo.

Pan H, Li WJ, Yao XJ, Wu YY, Liu LL, He HM, Zhang RL, Ma YF, Cai LT.

Small. 2017 May;13(17). doi: 10.1002/smll.201604036. Epub 2017 Feb 20.


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