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Items: 27


Distinct Imprinting Signatures and Biased Differentiation of Human Androgenetic and Parthenogenetic Embryonic Stem Cells.

Sagi I, De Pinho JC, Zuccaro MV, Atzmon C, Golan-Lev T, Yanuka O, Prosser R, Sadowy A, Perez G, Cabral T, Glaser B, Tsang SH, Goland R, Sauer MV, Lobo R, Benvenisty N, Egli D.

Cell Stem Cell. 2019 Sep 5;25(3):419-432.e9. doi: 10.1016/j.stem.2019.06.013.


Genome-wide Screen for Culture Adaptation and Tumorigenicity-Related Genes in Human Pluripotent Stem Cells.

Weissbein U, Peretz M, Plotnik O, Yanuka O, Sagi I, Golan-Lev T, Benvenisty N.

iScience. 2019 Jan 25;11:398-408. doi: 10.1016/j.isci.2018.12.031. Epub 2019 Jan 3.


Epigenetic mechanism of FMR1 inactivation in Fragile X syndrome.

Hecht M, Tabib A, Kahan T, Orlanski S, Gropp M, Tabach Y, Yanuka O, Benvenisty N, Keshet I, Cedar H.

Int J Dev Biol. 2017;61(3-4-5):285-292. doi: 10.1387/ijdb.170022hc.


Molecular Characterization of Down Syndrome Embryonic Stem Cells Reveals a Role for RUNX1 in Neural Differentiation.

Halevy T, Biancotti JC, Yanuka O, Golan-Lev T, Benvenisty N.

Stem Cell Reports. 2016 Oct 11;7(4):777-786. doi: 10.1016/j.stemcr.2016.08.003. Epub 2016 Sep 8.


Derivation and differentiation of haploid human embryonic stem cells.

Sagi I, Chia G, Golan-Lev T, Peretz M, Weissbein U, Sui L, Sauer MV, Yanuka O, Egli D, Benvenisty N.

Nature. 2016 Apr 7;532(7597):107-11. doi: 10.1038/nature17408. Epub 2016 Mar 16.


Reversion of FMR1 Methylation and Silencing by Editing the Triplet Repeats in Fragile X iPSC-Derived Neurons.

Park CY, Halevy T, Lee DR, Sung JJ, Lee JS, Yanuka O, Benvenisty N, Kim DW.

Cell Rep. 2015 Oct 13;13(2):234-41. doi: 10.1016/j.celrep.2015.08.084. Epub 2015 Oct 1.


Aberrant DNA methylation in ES cells.

Ludwig G, Nejman D, Hecht M, Orlanski S, Abu-Remaileh M, Yanuka O, Sandler O, Marx A, Roberts D, Benvenisty N, Bergman Y, Mendelsohn M, Cedar H.

PLoS One. 2014 May 22;9(5):e96090. doi: 10.1371/journal.pone.0096090. eCollection 2014.


The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome.

Stelzer Y, Sagi I, Yanuka O, Eiges R, Benvenisty N.

Nat Genet. 2014 Jun;46(6):551-7. doi: 10.1038/ng.2968. Epub 2014 May 11.


Human pluripotent stem cells with distinct X inactivation status show molecular and cellular differences controlled by the X-Linked ELK-1 gene.

Bruck T, Yanuka O, Benvenisty N.

Cell Rep. 2013 Jul 25;4(2):262-70. doi: 10.1016/j.celrep.2013.06.026. Epub 2013 Jul 18.


Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen.

Ben-David U, Gan QF, Golan-Lev T, Arora P, Yanuka O, Oren YS, Leikin-Frenkel A, Graf M, Garippa R, Boehringer M, Gromo G, Benvenisty N.

Cell Stem Cell. 2013 Feb 7;12(2):167-79. doi: 10.1016/j.stem.2012.11.015. Epub 2013 Jan 11.


Reprogramming of the MHC-I and its regulation by NFκB in human-induced pluripotent stem cells.

Pick M, Ronen D, Yanuka O, Benvenisty N.

Stem Cells. 2012 Dec;30(12):2700-8. doi: 10.1002/stem.1242.


Global analysis of parental imprinting in human parthenogenetic induced pluripotent stem cells.

Stelzer Y, Yanuka O, Benvenisty N.

Nat Struct Mol Biol. 2011 Jun;18(6):735-41. doi: 10.1038/nsmb.2050. Epub 2011 May 15.


Human embryonic stem cells as models for aneuploid chromosomal syndromes.

Biancotti JC, Narwani K, Buehler N, Mandefro B, Golan-Lev T, Yanuka O, Clark A, Hill D, Benvenisty N, Lavon N.

Stem Cells. 2010 Sep;28(9):1530-40. doi: 10.1002/stem.483.


Teratogen screening using transcriptome profiling of differentiating human embryonic stem cells.

Mayshar Y, Yanuka O, Benvenisty N.

J Cell Mol Med. 2011 Jun;15(6):1393-401. doi: 10.1111/j.1582-4934.2010.01105.x. Epub 2010 Jun 17.


Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos.

Eiges R, Urbach A, Malcov M, Frumkin T, Schwartz T, Amit A, Yaron Y, Eden A, Yanuka O, Benvenisty N, Ben-Yosef D.

Cell Stem Cell. 2007 Nov;1(5):568-77. doi: 10.1016/j.stem.2007.09.001.


Molecular analysis of LEFTY-expressing cells in early human embryoid bodies.

Dvash T, Sharon N, Yanuka O, Benvenisty N.

Stem Cells. 2007 Feb;25(2):465-72. Epub 2006 Oct 12.


The effect of overexpression of Pdx1 and Foxa2 on the differentiation of human embryonic stem cells into pancreatic cells.

Lavon N, Yanuka O, Benvenisty N.

Stem Cells. 2006 Aug;24(8):1923-30. Epub 2006 May 4.


Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies.

Dvash T, Mayshar Y, Darr H, McElhaney M, Barker D, Yanuka O, Kotkow KJ, Rubin LL, Benvenisty N, Eiges R.

Hum Reprod. 2004 Dec;19(12):2875-83. Epub 2004 Sep 16.


Differentiation and isolation of hepatic-like cells from human embryonic stem cells.

Lavon N, Yanuka O, Benvenisty N.

Differentiation. 2004 Jun;72(5):230-8.


Induced neuronal differentiation of human embryonic stem cells.

Schuldiner M, Eiges R, Eden A, Yanuka O, Itskovitz-Eldor J, Goldstein RS, Benvenisty N.

Brain Res. 2001 Sep 21;913(2):201-5.


Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells.

Eiges R, Schuldiner M, Drukker M, Yanuka O, Itskovitz-Eldor J, Benvenisty N.

Curr Biol. 2001 Apr 3;11(7):514-8.


Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells.

Schuldiner M, Yanuka O, Itskovitz-Eldor J, Melton DA, Benvenisty N.

Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11307-12.


Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers.

Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M, Soreq H, Benvenisty N.

Mol Med. 2000 Feb;6(2):88-95.


The tmp gene, encoding a membrane protein, is a c-Myc target with a tumorigenic activity.

Ben-Porath I, Yanuka O, Benvenisty N.

Mol Cell Biol. 1999 May;19(5):3529-39.


Involvement of Myc targets in c-myc and N-myc induced human tumors.

Ben-Yosef T, Yanuka O, Halle D, Benvenisty N.

Oncogene. 1998 Jul 16;17(2):165-71.


ECA39 is regulated by c-Myc in human and by a Jun/Fos homolog, Gcn4, in yeast.

Ben-Yosef T, Yanuka O, Benvenisty N.

Oncogene. 1996 Nov 7;13(9):1859-66.


ECA39, a conserved gene regulated by c-Myc in mice, is involved in G1/S cell cycle regulation in yeast.

Schuldiner O, Eden A, Ben-Yosef T, Yanuka O, Simchen G, Benvenisty N.

Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7143-8.

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