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Items: 24

1.

Influence of long term administration of tofogliflozin on chronic inflammation of visceral adipose tissue in mice with obesity induced by a high-fat diet.

Shirakawa K, Yano W, Inoue K, Katsumata Y, Endo J, Sano M.

PLoS One. 2019 Jan 25;14(1):e0211387. doi: 10.1371/journal.pone.0211387. eCollection 2019.

2.

Dipeptidyl peptidase 4 inhibitor anagliptin ameliorates hypercholesterolemia in hypercholesterolemic mice through inhibition of intestinal cholesterol transport.

Goto M, Furuta S, Yamashita S, Hashimoto H, Yano W, Inoue N, Kato N, Kaku K.

J Diabetes Investig. 2018 Nov;9(6):1261-1269. doi: 10.1111/jdi.12860. Epub 2018 Jun 5.

3.

TAS-114, a First-in-Class Dual dUTPase/DPD Inhibitor, Demonstrates Potential to Improve Therapeutic Efficacy of Fluoropyrimidine-Based Chemotherapy.

Yano W, Yokogawa T, Wakasa T, Yamamura K, Fujioka A, Yoshisue K, Matsushima E, Miyahara S, Miyakoshi H, Taguchi J, Chong KT, Takao Y, Fukuoka M, Matsuo K.

Mol Cancer Ther. 2018 Aug;17(8):1683-1693. doi: 10.1158/1535-7163.MCT-17-0911. Epub 2018 May 10.

4.

Metabolic effects of Tofogliflozin are efficiently enhanced with appropriate dietary carbohydrate ratio and are distinct from carbohydrate restriction.

Ito S, Hosaka T, Yano W, Itou T, Yasumura M, Shimizu Y, Kobayashi H, Nakagawa T, Inoue K, Tanabe S, Kondo T, Ishida H.

Physiol Rep. 2018 Mar;6(5). doi: 10.14814/phy2.13642.

5.

Characterization of the Adaptive Morphology of Japanese Stream Toad (Bufo torrenticola) Using Geometric Morphometrics.

Tokita M, Hasegawa Y, Yano W, Tsuji H.

Zoolog Sci. 2018 Feb;35(1):99-108. doi: 10.2108/zs170099.

PMID:
29417890
6.

Cranial shape evolution in adaptive radiations of birds: comparative morphometrics of Darwin's finches and Hawaiian honeycreepers.

Tokita M, Yano W, James HF, Abzhanov A.

Philos Trans R Soc Lond B Biol Sci. 2017 Feb 5;372(1713). pii: 20150481.

7.

Mechanism of lipid-lowering action of the dipeptidyl peptidase-4 inhibitor, anagliptin, in low-density lipoprotein receptor-deficient mice.

Yano W, Inoue N, Ito S, Itou T, Yasumura M, Yoshinaka Y, Hagita S, Goto M, Nakagawa T, Inoue K, Tanabe S, Kaku K.

J Diabetes Investig. 2017 Mar;8(2):155-160. doi: 10.1111/jdi.12593. Epub 2016 Dec 15.

8.

Semicircular Canal Size and Locomotion in Colobine Monkeys: A Cautionary Tale.

Rae TC, Johnson PM, Yano W, Hirasaki E.

Folia Primatol (Basel). 2016;87(4):213-223. Epub 2016 Oct 26.

9.

Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance.

Sasaki Y, Ohta M, Desai D, Figueiredo JL, Whelan MC, Sugano T, Yamabi M, Yano W, Faits T, Yabusaki K, Zhang H, Mlynarchik AK, Inoue K, Mizuno K, Aikawa M.

PLoS One. 2015 Jul 1;10(7):e0131176. doi: 10.1371/journal.pone.0131176. eCollection 2015.

10.

Patterns of morphological variation in enamel-dentin junction and outer enamel surface of human molars.

Morita W, Yano W, Nagaoka T, Abe M, Ohshima H, Nakatsukasa M.

J Anat. 2014 Jun;224(6):669-80. doi: 10.1111/joa.12180. Epub 2014 Apr 1.

11.

Size and shape variability in human molars during odontogenesis.

Morita W, Yano W, Nagaoka T, Abe M, Nakatsukasa M.

J Dent Res. 2014 Mar;93(3):275-80. doi: 10.1177/0022034513519268. Epub 2014 Jan 10.

PMID:
24413405
12.

1,2,3-Triazole-containing uracil derivatives with excellent pharmacokinetics as a novel class of potent human deoxyuridine triphosphatase inhibitors.

Miyakoshi H, Miyahara S, Yokogawa T, Endoh K, Muto T, Yano W, Wakasa T, Ueno H, Chong KT, Taguchi J, Nomura M, Takao Y, Fujioka A, Hashimoto A, Itou K, Yamamura K, Shuto S, Nagasawa H, Fukuoka M.

J Med Chem. 2012 Jul 26;55(14):6427-37. doi: 10.1021/jm3004174. Epub 2012 Jul 3.

PMID:
22715973
13.

Discovery of highly potent human deoxyuridine triphosphatase inhibitors based on the conformation restriction strategy.

Miyahara S, Miyakoshi H, Yokogawa T, Chong KT, Taguchi J, Muto T, Endoh K, Yano W, Wakasa T, Ueno H, Takao Y, Fujioka A, Hashimoto A, Itou K, Yamamura K, Nomura M, Nagasawa H, Shuto S, Fukuoka M.

J Med Chem. 2012 Jun 14;55(11):5483-96. doi: 10.1021/jm300416h. Epub 2012 May 30.

PMID:
22607122
14.

Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors.

Miyakoshi H, Miyahara S, Yokogawa T, Chong KT, Taguchi J, Endoh K, Yano W, Wakasa T, Ueno H, Takao Y, Nomura M, Shuto S, Nagasawa H, Fukuoka M.

J Med Chem. 2012 Apr 12;55(7):2960-9. doi: 10.1021/jm201627n. Epub 2012 Mar 26.

PMID:
22404301
15.

Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors.

Miyahara S, Miyakoshi H, Yokogawa T, Chong KT, Taguchi J, Muto T, Endoh K, Yano W, Wakasa T, Ueno H, Takao Y, Fujioka A, Hashimoto A, Itou K, Yamamura K, Nomura M, Nagasawa H, Shuto S, Fukuoka M.

J Med Chem. 2012 Apr 12;55(7):2970-80. doi: 10.1021/jm201628y. Epub 2012 Mar 26.

PMID:
22339362
16.

Earliest colobine skeletons from Nakali, Kenya.

Nakatsukasa M, Mbua E, Sawada Y, Sakai T, Nakaya H, Yano W, Kunimatsu Y.

Am J Phys Anthropol. 2010 Nov;143(3):365-82. doi: 10.1002/ajpa.21327.

PMID:
20949609
17.

Prenatal ontogeny of subspecific variation in the craniofacial morphology of the Japanese macaque (Macaca fuscata).

Yano W, Egi N, Takano T, Ogihara N.

Primates. 2010 Jul;51(3):263-71. doi: 10.1007/s10329-010-0197-3. Epub 2010 Apr 2.

PMID:
20361348
18.

Molecular mechanism of moderate insulin resistance in adiponectin-knockout mice.

Yano W, Kubota N, Itoh S, Kubota T, Awazawa M, Moroi M, Sugi K, Takamoto I, Ogata H, Tokuyama K, Noda T, Terauchi Y, Ueki K, Kadowaki T.

Endocr J. 2008 Jul;55(3):515-22. Epub 2008 Apr 30.

19.

Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.

Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T.

Cell Metab. 2007 Jul;6(1):55-68.

20.

Promotion of corneal epithelial wound healing in vitro and in vivo by annexin A5.

Watanabe M, Kondo S, Mizuno K, Yano W, Nakao H, Hattori Y, Kimura K, Nishida T.

Invest Ophthalmol Vis Sci. 2006 May;47(5):1862-8.

PMID:
16638992
21.

Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways.

Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T.

J Biol Chem. 2006 Mar 31;281(13):8748-55. Epub 2006 Jan 23.

22.

Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.

Kubota N, Terauchi Y, Tobe K, Yano W, Suzuki R, Ueki K, Takamoto I, Satoh H, Maki T, Kubota T, Moroi M, Okada-Iwabu M, Ezaki O, Nagai R, Ueta Y, Kadowaki T, Noda T.

J Clin Invest. 2004 Oct;114(7):917-27.

23.

Up-regulation of urokinase-type plasminogen activator in corneal epithelial cells induced by wounding.

Watanabe M, Yano W, Kondo S, Hattori Y, Yamada N, Yanai R, Nishida T.

Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3332-8.

PMID:
12882778
24.

Disruption of adiponectin causes insulin resistance and neointimal formation.

Kubota N, Terauchi Y, Yamauchi T, Kubota T, Moroi M, Matsui J, Eto K, Yamashita T, Kamon J, Satoh H, Yano W, Froguel P, Nagai R, Kimura S, Kadowaki T, Noda T.

J Biol Chem. 2002 Jul 19;277(29):25863-6. Epub 2002 May 24.

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