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Histological changes in patients who developed hepatocellular carcinoma after hepatitis C virus eradication by interferon-based therapy.

Kawaguchi T, Ide T, Kondo R, Nomura Y, Arinaga-Hino T, Kuwahara R, Amano K, Sano T, Akiba J, Ohshima K, Yano H, Torimura T.

Exp Ther Med. 2019 Nov;18(5):3991-4001. doi: 10.3892/etm.2019.8024. Epub 2019 Sep 18.


Inhibitory receptors and ligands beyond PD-1, PD-L1 and CTLA-4: breakthroughs or backups.

Andrews LP, Yano H, Vignali DAA.

Nat Immunol. 2019 Oct 14. doi: 10.1038/s41590-019-0512-0. [Epub ahead of print] Review.


Leptomeningeal metastases arising from gynecological cancers.

Yano H, Nagao S, Yamaguchi S.

Int J Clin Oncol. 2019 Oct 4. doi: 10.1007/s10147-019-01556-1. [Epub ahead of print]


Correlation between microstructure of CAD/CAM composites and the silanization effect on adhesive bonding.

Yano HT, Ikeda H, Nagamatsu Y, Masaki C, Hosokawa R, Shimizu H.

J Mech Behav Biomed Mater. 2019 Sep 18;101:103441. doi: 10.1016/j.jmbbm.2019.103441. [Epub ahead of print]


Abdominal Aortic Graft Infection Caused by stG485.0, ST29 Streptococcus dysgalactiae subsp. equisimilis.

Kakuta R, Shimizu T, Goto H, Endo S, Kanamori H, Ohta N, Nakano R, Yano H, Katori Y, Kaku M.

Jpn J Infect Dis. 2019 Sep 30. doi: 10.7883/yoken.JJID.2019.171. [Epub ahead of print]


Scrotal ulcer due to community-acquired methicillin-resistant Staphylococcus aureus USA300 clone in an HIV-positive man who has sex with men in Japan: a case report.

Ogawa Y, Kasahara K, Asada T, Yoshihara S, Hirai N, Furukawa R, Nishimura T, Ohmori K, Nakano R, Yano H, Mikasa K.

Int J STD AIDS. 2019 Sep 27:956462419870986. doi: 10.1177/0956462419870986. [Epub ahead of print] No abstract available.


Diverse histomorphology of HER2 positive breast carcinomas based on differential ER expression.

Akashi M, Yamaguchi R, Kusano H, Obara H, Yamaguchi M, Toh U, Akiba J, Kakuma T, Tanaka M, Akagi Y, Yano H.

Histopathology. 2019 Sep 25. doi: 10.1111/his.14003. [Epub ahead of print]


Effect of evolocumab therapy on coronary fibrous cap thickness assessed by optical coherence tomography in patients with acute coronary syndrome.

Yano H, Horinaka S, Ishimitsu T.

J Cardiol. 2019 Sep 5. pii: S0914-5087(19)30251-5. doi: 10.1016/j.jjcc.2019.08.002. [Epub ahead of print]


Sparassis crispa Intake Improves the Reduced Lipopolysaccharide-Induced TNF-α Production That Occurs upon Exhaustive Exercise in Mice.

Uchida M, Horii N, Hasegawa N, Oyanagi E, Yano H, Iemitsu M.

Nutrients. 2019 Sep 2;11(9). pii: E2049. doi: 10.3390/nu11092049.


Factors Enhancing Serum Syndecan-1 Concentrations: A Large-Scale Comprehensive Medical Examination.

Oda K, Okada H, Suzuki A, Tomita H, Kobayashi R, Sumi K, Suzuki K, Takada C, Ishihara T, Suzuki K, Kano S, Kondo K, Iwashita Y, Yano H, Zaikokuji R, Sampei S, Fukuta T, Kitagawa Y, Okamoto H, Watanabe T, Kawaguchi T, Kojima T, Deguchi F, Miyazaki N, Yamada N, Doi T, Yoshida T, Ushikoshi H, Yoshida S, Takemura G, Ogura S.

J Clin Med. 2019 Aug 27;8(9). pii: E1320. doi: 10.3390/jcm8091320.


Images from the surface of asteroid Ryugu show rocks similar to carbonaceous chondrite meteorites.

Jaumann R, Schmitz N, Ho TM, Schröder SE, Otto KA, Stephan K, Elgner S, Krohn K, Preusker F, Scholten F, Biele J, Ulamec S, Krause C, Sugita S, Matz KD, Roatsch T, Parekh R, Mottola S, Grott M, Michel P, Trauthan F, Koncz A, Michaelis H, Lange C, Grundmann JT, Maibaum M, Sasaki K, Wolff F, Reill J, Moussi-Soffys A, Lorda L, Neumann W, Vincent JB, Wagner R, Bibring JP, Kameda S, Yano H, Watanabe S, Yoshikawa M, Tsuda Y, Okada T, Yoshimitsu T, Mimasu Y, Saiki T, Yabuta H, Rauer H, Honda R, Morota T, Yokota Y, Kouyama T.

Science. 2019 Aug 23;365(6455):817-820. doi: 10.1126/science.aaw8627.


A Novel Mismatched PCR-Restriction Fragment Length Polymorphism Assay for Rapid Detection of gyrA and parC Mutations Associated With Fluoroquinolone Resistance in Acinetobacter baumannii.

Kakuta N, Nakano R, Nakano A, Suzuki Y, Tanouchi A, Masui T, Horiuchi S, Endo S, Kakuta R, Ono Y, Yano H.

Ann Lab Med. 2020 Jan;40(1):27-32. doi: 10.3343/alm.2020.40.1.27.


Painful swelling of the arm due to a bizarre intramuscular vascular malformation.

Theodorou DJ, Theodorou SJ, Yano H, Chosa E, Marutsuka K, Kakitsubata Y.

J Orthop Sci. 2019 Aug 17. pii: S0949-2658(19)30240-4. doi: 10.1016/j.jos.2019.07.011. [Epub ahead of print] No abstract available.


Phagocytic elimination of synapses by microglia during sleep.

Choudhury ME, Miyanishi K, Takeda H, Islam A, Matsuoka N, Kubo M, Matsumoto S, Kunieda T, Nomoto M, Yano H, Tanaka J.

Glia. 2019 Aug 19. doi: 10.1002/glia.23698. [Epub ahead of print]


A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter.

Slack RD, Abramyan AM, Tang H, Meena S, Davis BA, Bonifazi A, Giancola JB, Deschamps JR, Naing S, Yano H, Singh SK, Newman AH, Shi L.

ACS Chem Neurosci. 2019 Sep 18;10(9):3946-3952. doi: 10.1021/acschemneuro.9b00375. Epub 2019 Aug 22.


Significance of neoadjuvant chemoradiotherapy for borderline resectable pancreatic head cancer: Pathological local invasion and microvessel invasion analysis.

Naito Y, Ishikawa H, Sadashima E, Okabe Y, Takahashi K, Kawahara R, Hisaka T, Fukahori M, Ushijima T, Ishida Y, Tanigawa M, Mihara Y, Nakayama M, Kondo R, Kusano H, Takase Y, Abe H, Ogo E, Okuda K, Shimamatsu K, Yano H, Akiba J.

Mol Clin Oncol. 2019 Sep;11(3):225-233. doi: 10.3892/mco.2019.1885. Epub 2019 Jun 20.


Programmed death-ligand 1 expression is an unfavorable prognostic factor of hepatocellular carcinoma after archiving sustained virologic response for hepatitis C virus infection.

Kondo R, Akiba J, Ogasawara S, Nakashima O, Naito Y, Kusano H, Mihara Y, Tanigawa M, Yano H.

Oncol Lett. 2019 Aug;18(2):1458-1466. doi: 10.3892/ol.2019.10448. Epub 2019 Jun 7.


Usefulness of positron emission tomography for differentiating gliomas according to the 2016 World Health Organization classification of tumors of the central nervous system.

Takei H, Shinoda J, Ikuta S, Maruyama T, Muragaki Y, Kawasaki T, Ikegame Y, Okada M, Ito T, Asano Y, Yokoyama K, Nakayama N, Yano H, Iwama T.

J Neurosurg. 2019 Aug 16:1-10. doi: 10.3171/2019.5.JNS19780. [Epub ahead of print]


KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells.

Okamoto K, Tanaka Y, Ogasawara S, Obuse C, Nakayama JI, Yano H, Tsuneoka M.

Oncotarget. 2019 Jul 30;10(46):4743-4760. doi: 10.18632/oncotarget.27092. eCollection 2019 Jul 30.


A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases.

Nishimiya D, Kawaguchi Y, Kodama S, Nasu H, Yano H, Yamaguchi A, Tamura M, Hashimoto R.

Sci Rep. 2019 Aug 7;9(1):11436. doi: 10.1038/s41598-019-47615-5.


Discontinuation of disease-modifying therapy for patients with relapsing-remitting multiple sclerosis: Effect on clinical and MRI outcomes.

Yano H, Gonzalez C, Healy BC, Glanz BI, Weiner HL, Chitnis T.

Mult Scler Relat Disord. 2019 Jul 25;35:119-127. doi: 10.1016/j.msard.2019.07.021. [Epub ahead of print]


Sarcomatous Component in Pancreatic Adenosquamous Carcinoma: A Clinicopathological Series of 7 Cases.

Taniwaki S, Hisaka T, Sakai H, Goto Y, Nomura Y, Kawahara R, Ishikawa H, Yasunaga M, Naito Y, Akiba J, Yano H, Tanaka H, Akagi Y, Okuda K.

Anticancer Res. 2019 Aug;39(8):4575-4580. doi: 10.21873/anticanres.13636.


Clinicopathological Study of Resections of Intraductal Papillary Neoplasm of the Bile Duct.

Sato T, Hisaka T, Sakai H, Ishikawa H, Kawahara R, Goto Y, Nomura Y, Yasunaga M, Fujita F, Tanigawa M, Naito Y, Akiba J, Yano H, Tanaka H, Akagi Y, Okuda K.

Anticancer Res. 2019 Aug;39(8):4569-4573. doi: 10.21873/anticanres.13635.


Clinical and Prognostic Significance of Neoplastic Spindle Cells in Gallbladder Cancer.

Midorikawa R, Hisaka T, Sakai H, Nomura Y, Goto Y, Sato T, Kawahara R, Ishikawa H, Fujita F, Yasunaga M, Tanigawa M, Naito Y, Akiba J, Yano H, Tanaka H, Akagi Y, Okuda K.

Anticancer Res. 2019 Aug;39(8):4561-4568. doi: 10.21873/anticanres.13634.


Sinusoidal Obstruction Syndrome and Postoperative Complications Resulting from Preoperative Chemotherapy for Colorectal Cancer Liver Metastasis.

Hisaka T, Ishikawa H, Sakai H, Kawahara R, Goto Y, Nomura Y, Yasunaga M, Kinugasa T, Fujita F, Mizobe T, Fukahori M, Miwa K, Nakashima O, Tanigawa M, Naito Y, Akiba J, Yano H, Tanaka H, Akagi Y, Okuda K.

Anticancer Res. 2019 Aug;39(8):4549-4554. doi: 10.21873/anticanres.13632.


Expression of Matrix Metalloproteinases in Intraductal Papillary Mucinous Neoplasm of the Pancreas.

Akashi M, Hisaka T, Sakai H, Ishikawa H, Kawahara R, Goto Y, Nomura Y, Yasunaga M, Fujita F, Tanigawa M, Naito Y, Akiba J, Yano H, Tanaka H, Akagi Y, Okuda K.

Anticancer Res. 2019 Aug;39(8):4485-4490. doi: 10.21873/anticanres.13623.


Recent practical researches in the development of gluten-free breads.

Yano H.

NPJ Sci Food. 2019 May 1;3:7. doi: 10.1038/s41538-019-0040-1. eCollection 2019. Review.


Anti-apoptotic effect by the suppression of IRF1 as a downstream of Wnt/β-catenin signaling in colorectal cancer cells.

Ohsugi T, Yamaguchi K, Zhu C, Ikenoue T, Takane K, Shinozaki M, Tsurita G, Yano H, Furukawa Y.

Oncogene. 2019 Aug;38(32):6051-6064. doi: 10.1038/s41388-019-0856-9. Epub 2019 Jul 10.


TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas.

Tanaka A, Matsuse M, Saenko V, Nakao T, Yamanouchi K, Sakimura C, Yano H, Nishihara E, Hirokawa M, Suzuki K, Miyauchi A, Eguchi S, Yoshiura KI, Yamashita S, Nagayasu T, Mitsutake N.

Thyroid. 2019 Aug;29(8):1105-1114. doi: 10.1089/thy.2018.0695. Epub 2019 Aug 5.


Phase II trial of paclitaxel, carboplatin, and bevacizumab for advanced or recurrent cervical cancer.

Suzuki K, Nagao S, Shibutani T, Yamamoto K, Jimi T, Yano H, Kitai M, Shiozaki T, Matsuoka K, Yamaguchi S.

Gynecol Oncol. 2019 Sep;154(3):554-557. doi: 10.1016/j.ygyno.2019.05.018. Epub 2019 Jul 5.


Usefulness of Attenuation Imaging with an Ultrasound Scanner for the Evaluation of Hepatic Steatosis.

Tada T, Iijima H, Kobayashi N, Yoshida M, Nishimura T, Kumada T, Kondo R, Yano H, Kage M, Nakano C, Aoki T, Aizawa N, Ikeda N, Takashima T, Yuri Y, Ishii N, Hasegawa K, Takata R, Yoh K, Sakai Y, Nishikawa H, Iwata Y, Enomoto H, Hirota S, Fujimoto J, Nishiguchi S.

Ultrasound Med Biol. 2019 Oct;45(10):2679-2687. doi: 10.1016/j.ultrasmedbio.2019.05.033. Epub 2019 Jul 3.


Case of endobronchial metastasis from breast cancer accompanied with Cunninghamella bertholletiae tracheobronchial mycetoma.

Uno K, Hishiya N, Matsuda M, Kai Y, Amano M, Nakamura A, Tohjyo T, Kawaguchi T, Nakano R, Yano H, Kasahara K, Mikasa K.

J Infect Chemother. 2019 Jun 18. pii: S1341-321X(19)30166-7. doi: 10.1016/j.jiac.2019.05.031. [Epub ahead of print]


High-Frequency Activation of Nucleus Accumbens D1-MSNs Drives Excitatory Potentiation on D2-MSNs.

Francis TC, Yano H, Demarest TG, Shen H, Bonci A.

Neuron. 2019 Aug 7;103(3):432-444.e3. doi: 10.1016/j.neuron.2019.05.031. Epub 2019 Jun 17.


Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma.

Sanada T, Islam A, Kaminota T, Kirino Y, Tanimoto R, Yoshimitsu H, Yano H, Mizuno Y, Okada M, Mitani S, Ugumori T, Tanaka J, Hato N.

Laryngoscope. 2019 Jun 20. doi: 10.1002/lary.28142. [Epub ahead of print]


Genetic relatedness of Mycobacterium avium subsp. hominissuis isolates from bathrooms of healthy volunteers, rivers, and soils in Japan with human clinical isolates from different geographical areas.

Arikawa K, Ichijo T, Nakajima S, Nishiuchi Y, Yano H, Tamaru A, Yoshida S, Maruyama F, Ota A, Nasu M, Starkova DA, Mokrousov I, Narvskaya OV, Iwamoto T.

Infect Genet Evol. 2019 Oct;74:103923. doi: 10.1016/j.meegid.2019.103923. Epub 2019 Jun 14.


Vessels Encapsulating Tumor Clusters (VETC) Is a Powerful Predictor of Aggressive Hepatocellular Carcinoma.

Renne SL, Woo HY, Allegra S, Rudini N, Yano H, Donadon M, Viganò L, Akiba J, Lee HS, Rhee H, Park YN, Roncalli M, Di Tommaso L.

Hepatology. 2019 Jun 17. doi: 10.1002/hep.30814. [Epub ahead of print]


Development of a loop-mediated isothermal amplification assay for rapid Helicobacter pylori detection.

Horiuchi S, Nakano R, Nakano A, Hishiya N, Uno K, Suzuki Y, Tanouchi A, Kakuta N, Masui T, Jojima N, Yano H.

J Microbiol Methods. 2019 Aug;163:105653. doi: 10.1016/j.mimet.2019.105653. Epub 2019 Jun 11.


Peritonitis due to Moraxella osloensis: A case report and literature review.

Yamada A, Kasahara K, Ogawa Y, Samejima K, Eriguchi M, Yano H, Mikasa K, Tsuruya K.

J Infect Chemother. 2019 Jun 10. pii: S1341-321X(19)30150-3. doi: 10.1016/j.jiac.2019.05.018. [Epub ahead of print]


Hepatectomy for metachronous colorectal liver metastases following complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal metastases: a report of three cases.

Ito K, Takemura N, Inagaki F, Mihara F, Kurokawa T, Gohda Y, Kiyomatsu T, Yano H, Kokudo N.

World J Surg Oncol. 2019 Jun 13;17(1):99. doi: 10.1186/s12957-019-1646-0.


Prognostic impact of p16 and PD-L1 expression in patients with oropharyngeal squamous cell carcinoma receiving a definitive treatment.

Sato F, Ono T, Kawahara A, Kawaguchi T, Tanaka H, Shimamatsu K, Kakuma T, Akiba J, Umeno H, Yano H.

J Clin Pathol. 2019 Aug;72(8):542-549. doi: 10.1136/jclinpath-2019-205818. Epub 2019 May 21.


Neutrophil Elastase Damages the Pulmonary Endothelial Glycocalyx in Lipopolysaccharide-Induced Experimental Endotoxemia.

Suzuki K, Okada H, Takemura G, Takada C, Kuroda A, Yano H, Zaikokuji R, Morishita K, Tomita H, Oda K, Matsuo S, Uchida A, Fukuta T, Sampei S, Miyazaki N, Kawaguchi T, Watanabe T, Yoshida T, Ushikoshi H, Yoshida S, Maekawa Y, Ogura S.

Am J Pathol. 2019 Aug;189(8):1526-1535. doi: 10.1016/j.ajpath.2019.05.002. Epub 2019 May 18.


Development of an MSI-positive colon tumor with aberrant DNA methylation in a PPAP patient.

Yamaguchi K, Shimizu E, Yamaguchi R, Imoto S, Komura M, Hatakeyama S, Noguchi R, Takane K, Ikenoue T, Gohda Y, Yano H, Miyano S, Furukawa Y.

J Hum Genet. 2019 Aug;64(8):729-740. doi: 10.1038/s10038-019-0611-7. Epub 2019 May 14.


Intratumoral regulatory T cells: markers, subsets and their impact on anti-tumor immunity.

Yano H, Andrews LP, Workman CJ, Vignali DAA.

Immunology. 2019 Jul;157(3):232-247. doi: 10.1111/imm.13067. Epub 2019 Jun 3. Review.


Malic enzyme 1 is a potential marker of combined hepatocellular cholangiocarcinoma, subtype with stem-cell features, intermediate-cell type.

Mihara Y, Akiba J, Ogasawara S, Kondo R, Fukushima H, Itadani H, Obara H, Kakuma T, Kusano H, Naito Y, Okuda K, Nakashima O, Yano H.

Hepatol Res. 2019 Sep;49(9):1066-1075. doi: 10.1111/hepr.13365. Epub 2019 Jun 18.


High sex hormone-binding globulin concentration is a risk factor for high fibrosis-4 index in middle-aged Japanese men.

Fujihara Y, Hamanoue N, Yano H, Tanabe M, Akehi Y, Nomiyama T, Yanase T.

Endocr J. 2019 Jul 28;66(7):637-645. doi: 10.1507/endocrj.EJ18-0505. Epub 2019 May 9.


Expression and role of regulator of G-protein signaling 5 in squamous cell carcinoma of the tongue.

Abe Y, Ogasawara S, Akiba J, Naito Y, Kondo R, Nakamura K, Kusukawa J, Yano H.

Clin Exp Dent Res. 2019 Mar 4;5(2):160-169. doi: 10.1002/cre2.166. eCollection 2019 Apr.


Identification of reference genes for microRNAs of extracellular vesicles isolated from plasma samples of healthy dogs by ultracentrifugation, precipitation, and membrane affinity chromatography methods.

Narita M, Nishida H, Asahina R, Nakata K, Yano H, Ueda T, Inden M, Akiyoshi H, Maeda S, Kamishina H.

Am J Vet Res. 2019 May;80(5):449-454. doi: 10.2460/ajvr.80.5.449.


Insect Cuticle-Mimetic Hydrogels with High Mechanical Properties Achieved via the Combination of Chitin Nanofiber and Gelatin.

Chen C, Li D, Yano H, Abe K.

J Agric Food Chem. 2019 May 15;67(19):5571-5578. doi: 10.1021/acs.jafc.9b00984. Epub 2019 May 2.


Fully soluble self-doped poly(3,4-ethylenedioxythiophene) with an electrical conductivity greater than 1000 S cm-1.

Yano H, Kudo K, Marumo K, Okuzaki H.

Sci Adv. 2019 Apr 12;5(4):eaav9492. doi: 10.1126/sciadv.aav9492. eCollection 2019 Apr.


Nephrotic range proteinuria and metabolic alkalosis in Takayasu arteritis.

Tsuchida T, Yano H, Raita Y, Kinjo M.

BMJ Case Rep. 2019 Apr 15;12(4). pii: e228637. doi: 10.1136/bcr-2018-228637.


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