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Items: 12

1.

Inhibition of Heat shock protein 90 suppresses Twist1 transcription.

Chong KY, Kang M, Garofalo F, Ueno D, Liang H, Cady S, Madarikan O, Pitruzzello N, Tsai CH, Hartwich T, Shuch B, Yang-Hartwich Y.

Mol Pharmacol. 2019 Jun 7. pii: mol.119.116137. doi: 10.1124/mol.119.116137. [Epub ahead of print]

2.

Protein kinase Cα-mediated phosphorylation of Twist1 at Ser-144 prevents Twist1 ubiquitination and stabilizes it.

Tedja R, Roberts CM, Alvero AB, Cardenas C, Yang-Hartwich Y, Spadinger S, Pitruzzello M, Yin G, Glackin CA, Mor G.

J Biol Chem. 2019 Mar 29;294(13):5082-5093. doi: 10.1074/jbc.RA118.005921. Epub 2019 Feb 7.

PMID:
30733340
3.

Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors.

Li C, Bonazzoli E, Bellone S, Choi J, Dong W, Menderes G, Altwerger G, Han C, Manzano A, Bianchi A, Pettinella F, Manara P, Lopez S, Yadav G, Riccio F, Zammataro L, Zeybek B, Yang-Hartwich Y, Buza N, Hui P, Wong S, Ravaggi A, Bignotti E, Romani C, Todeschini P, Zanotti L, Zizioli V, Odicino F, Pecorelli S, Ardighieri L, Silasi DA, Litkouhi B, Ratner E, Azodi M, Huang GS, Schwartz PE, Lifton RP, Schlessinger J, Santin AD.

Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):619-624. doi: 10.1073/pnas.1814027116. Epub 2018 Dec 24. Erratum in: Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5829.

PMID:
30584090
4.

p53-Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT.

Yang-Hartwich Y, Tedja R, Roberts CM, Goodner-Bingham J, Cardenas C, Gurea M, Sumi NJ, Alvero AB, Glackin CA, Mor G.

Mol Cancer Res. 2019 Jan;17(1):153-164. doi: 10.1158/1541-7786.MCR-18-0238. Epub 2018 Aug 21.

PMID:
30131448
5.

TRX-E-002-1 Induces c-Jun-Dependent Apoptosis in Ovarian Cancer Stem Cells and Prevents Recurrence In Vivo.

Alvero AB, Heaton A, Lima E, Pitruzzello M, Sumi N, Yang-Hartwich Y, Cardenas C, Steinmacher S, Silasi DA, Brown D, Mor G.

Mol Cancer Ther. 2016 Jun;15(6):1279-90. doi: 10.1158/1535-7163.MCT-16-0005. Epub 2016 Apr 8.

6.

Murine model for non-invasive imaging to detect and monitor ovarian cancer recurrence.

Sumi NJ, Lima E, Pizzonia J, Orton SP, Craveiro V, Joo W, Holmberg JC, Gurrea M, Yang-Hartwich Y, Alvero A, Mor G.

J Vis Exp. 2014 Nov 2;(93):e51815. doi: 10.3791/51815.

7.

Detection of p53 protein transcriptional activity by chromatin immunoprecipitation.

Yang-Hartwich Y, Romanoff E, Bingham J, Alvero AB, Mor G.

Methods Mol Biol. 2015;1219:87-93. doi: 10.1007/978-1-4939-1661-0_8.

PMID:
25308264
8.

Detection of p53 protein aggregation in cancer cell lines and tumor samples.

Yang-Hartwich Y, Bingham J, Garofalo F, Alvero AB, Mor G.

Methods Mol Biol. 2015;1219:75-86. doi: 10.1007/978-1-4939-1661-0_7.

PMID:
25308263
9.

p53 protein aggregation promotes platinum resistance in ovarian cancer.

Yang-Hartwich Y, Soteras MG, Lin ZP, Holmberg J, Sumi N, Craveiro V, Liang M, Romanoff E, Bingham J, Garofalo F, Alvero A, Mor G.

Oncogene. 2015 Jul;34(27):3605-16. doi: 10.1038/onc.2014.296. Epub 2014 Sep 29.

PMID:
25263447
10.

Ovulation and extra-ovarian origin of ovarian cancer.

Yang-Hartwich Y, Gurrea-Soteras M, Sumi N, Joo WD, Holmberg JC, Craveiro V, Alvero AB, Mor G.

Sci Rep. 2014 Aug 19;4:6116. doi: 10.1038/srep06116.

11.

Phenotypic modifications in ovarian cancer stem cells following Paclitaxel treatment.

Craveiro V, Yang-Hartwich Y, Holmberg JC, Joo WD, Sumi NJ, Pizzonia J, Griffin B, Gill SK, Silasi DA, Azodi M, Rutherford T, Alvero AB, Mor G.

Cancer Med. 2013 Dec;2(6):751-62. doi: 10.1002/cam4.115. Epub 2013 Aug 27. Erratum in: Cancer Med. 2013 Dec;2(6):987. Joo, Won Duk [added].

12.

TLR2 enhances ovarian cancer stem cell self-renewal and promotes tumor repair and recurrence.

Chefetz I, Alvero AB, Holmberg JC, Lebowitz N, Craveiro V, Yang-Hartwich Y, Yin G, Squillace L, Gurrea Soteras M, Aldo P, Mor G.

Cell Cycle. 2013 Feb 1;12(3):511-21. doi: 10.4161/cc.23406. Epub 2013 Jan 16.

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