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Silicon confers protective effect against ginseng root rot by regulating sugar efflux into apoplast.

Abbai R, Kim YJ, Mohanan P, El-Agamy Farh M, Mathiyalagan R, Yang DU, Rangaraj S, Venkatachalam R, Kim YJ, Yang DC.

Sci Rep. 2019 Dec 3;9(1):18259. doi: 10.1038/s41598-019-54678-x.


Preparation of Polyethylene Glycol-Ginsenoside Rh1 and Rh2 Conjugates and Their Efficacy against Lung Cancer and Inflammation.

Mathiyalagan R, Wang C, Kim YJ, Castro-Aceituno V, Ahn S, Subramaniyam S, Simu SY, Jiménez-Pérez ZE, Yang DC, Jung SK.

Molecules. 2019 Nov 29;24(23). pii: E4367. doi: 10.3390/molecules24234367.


Synthesis of a Zinc Oxide Nanoflower Photocatalyst from Sea Buckthorn Fruit for Degradation of Industrial Dyes in Wastewater Treatment.

Rupa EJ, Kaliraj L, Abid S, Yang DC, Jung SK.

Nanomaterials (Basel). 2019 Nov 26;9(12). pii: E1692. doi: 10.3390/nano9121692.


PlantRegMap: charting functional regulatory maps in plants.

Tian F, Yang DC, Meng YQ, Jin J, Gao G.

Nucleic Acids Res. 2019 Nov 8. pii: gkz1020. doi: 10.1093/nar/gkz1020. [Epub ahead of print]


Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression.

Yang DC, Li JM, Xu J, Oldham J, Phan SH, Last JA, Wu R, Chen CH.

FASEB J. 2019 Dec;33(12):14354-14369. doi: 10.1096/fj.201901705R. Epub 2019 Oct 26.


Photoluminescent And Self-Assembled Hyaluronic Acid-Zinc Oxide-Ginsenoside Rh2 Nanoparticles And Their Potential Caspase-9 Apoptotic Mechanism Towards Cancer Cell Lines.

Kim YJ, Perumalsamy H, Castro-Aceituno V, Kim D, Markus J, Lee S, Kim S, Liu Y, Yang DC.

Int J Nanomedicine. 2019 Oct 9;14:8195-8208. doi: 10.2147/IJN.S221328. eCollection 2019.


LncRNA HOTAIR inhibited osteogenic differentiation of BMSCs by regulating Wnt/β-catenin pathway.

Shen JJ, Zhang CH, Chen ZW, Wang ZX, Yang DC, Zhang FL, Feng KH.

Eur Rev Med Pharmacol Sci. 2019 Sep;23(17):7232-7246. doi: 10.26355/eurrev_201909_18826.


Synthesis of panos extract mediated ZnO nano-flowers as photocatalyst for industrial dye degradation by UV illumination.

Kaliraj L, Ahn JC, Rupa EJ, Abid S, Lu J, Yang DC.

J Photochem Photobiol B. 2019 Oct;199:111588. doi: 10.1016/j.jphotobiol.2019.111588. Epub 2019 Aug 9.


Quantum Monte Carlo Study of the Water Dimer Binding Energy and Halogen-π Interactions.

Yang DC, Kim DY, Kim KS.

J Phys Chem A. 2019 Sep 12;123(36):7785-7791. doi: 10.1021/acs.jpca.9b04072. Epub 2019 Aug 28.


Development of species-specific chloroplast markers for the authentication of Gynostemma pentaphyllum and their distribution in the Korean peninsula.

Abid S, Mohanan P, Kaliraj L, Park JK, Ahn JC, Yang DC.

Fitoterapia. 2019 Oct;138:104295. doi: 10.1016/j.fitote.2019.104295. Epub 2019 Aug 7.


Molecular discrimination of Panax ginseng cultivar K-1 using pathogenesis-related protein 5 gene.

Wang H, Xu F, Wang X, Kwon WS, Yang DC.

J Ginseng Res. 2019 Jul;43(3):482-487. doi: 10.1016/j.jgr.2018.07.001. Epub 2018 Jul 9.


Long non-coding RNAs in Oral squamous cell carcinoma: biologic function, mechanisms and clinical implications.

Zhang L, Meng X, Zhu XW, Yang DC, Chen R, Jiang Y, Xu T.

Mol Cancer. 2019 May 27;18(1):102. doi: 10.1186/s12943-019-1021-3. Review.


A Genome-Wide Helicobacter pylori Morphology Screen Uncovers a Membrane-Spanning Helical Cell Shape Complex.

Yang DC, Blair KM, Taylor JA, Petersen TW, Sessler T, Tull CM, Leverich CK, Collar AL, Wyckoff TJ, Biboy J, Vollmer W, Salama NR.

J Bacteriol. 2019 Jun 21;201(14). pii: e00724-18. doi: 10.1128/JB.00724-18. Print 2019 Jul 15.


mACPpred: A Support Vector Machine-Based Meta-Predictor for Identification of Anticancer Peptides.

Boopathi V, Subramaniyam S, Malik A, Lee G, Manavalan B, Yang DC.

Int J Mol Sci. 2019 Apr 22;20(8). pii: E1964. doi: 10.3390/ijms20081964.


6-Methoxyflavonols from the aerial parts of Tetragonia tetragonoides (Pall.) Kuntze and their anti-inflammatory activity.

Lee YG, Lee H, Ryuk JA, Hwang JT, Kim HG, Lee DS, Kim YJ, Yang DC, Ko BS, Baek NI.

Bioorg Chem. 2019 Jul;88:102922. doi: 10.1016/j.bioorg.2019.102922. Epub 2019 Apr 11.


Rapid nickel(ii)-promoted cysteine S-arylation with arylboronic acids.

Hanaya K, Ohata J, Miller MK, Mangubat-Medina AE, Swierczynski MJ, Yang DC, Rosenthal RM, Popp BV, Ball ZT.

Chem Commun (Camb). 2019 Feb 28;55(19):2841-2844. doi: 10.1039/c9cc00159j.


Development of Lactobacillus kimchicus DCY51T-mediated gold nanoparticles for delivery of ginsenoside compound K: in vitro photothermal effects and apoptosis detection in cancer cells.

Kim YJ, Perumalsamy H, Markus J, Balusamy SR, Wang C, Ho Kang S, Lee S, Park SY, Kim S, Castro-Aceituno V, Kim SH, Yang DC.

Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):30-44. doi: 10.1080/21691401.2018.1541900.


Discovery of a new primer set for detection and quantification of Ilyonectria mors-panacis in soils for ginseng cultivation.

Farh ME, Han JA, Kim YJ, Kim JC, Singh P, Yang DC.

J Ginseng Res. 2019 Jan;43(1):1-9. doi: 10.1016/j.jgr.2017.07.002. Epub 2017 Jul 31.


A H₂O₂-Responsive Boron Dipyrromethene-Based Photosensitizer for Imaging-Guided Photodynamic Therapy.

Wang ZW, Su D, Li XQ, Cao JJ, Yang DC, Liu JY.

Molecules. 2018 Dec 21;24(1). pii: E32. doi: 10.3390/molecules24010032.


Synthesis of a Novel α-Glucosyl Ginsenoside F1 by Cyclodextrin Glucanotransferase and Its In Vitro Cosmetic Applications.

Moon SS, Lee HJ, Mathiyalagan R, Kim YJ, Yang DU, Lee DY, Min JW, Jimenez Z, Yang DC.

Biomolecules. 2018 Nov 10;8(4). pii: E142. doi: 10.3390/biom8040142.


Ornithinimicrobium panacihumi sp. nov., Antagonistic Bacteria Against Root Rot Fungal Pathogens, Isolated from Cultivated Ginseng Soil.

Huo Y, Kang JP, Ahn JC, Yang DU, Yang DC.

Curr Microbiol. 2019 Jan;76(1):22-28. doi: 10.1007/s00284-018-1579-9. Epub 2018 Oct 31.


Gold Nanoparticles Synthesized with Fresh Panax ginseng Leaf Extract Suppress Adipogenesis by Downregulating PPARγ/CEBPα Signaling in 3T3-L1 Mature Adipocytes.

Simu SY, Ahn S, Castro-Aceituno V, Singh P, Mathiyalagan R, Jiménez-Pérez ZE, Hurh J, Oi LZ, Hun NJ, Kim YJ, Yang DC.

J Nanosci Nanotechnol. 2019 Feb 1;19(2):701-708. doi: 10.1166/jnn.2019.15753.


Characterization of squalene-induced PgCYP736B involved in salt tolerance by modulating key genes of abscisic acid biosynthesis.

Balusamy SR, Rahimi S, Yang DC.

Int J Biol Macromol. 2019 Jan;121:796-805. doi: 10.1016/j.ijbiomac.2018.10.058. Epub 2018 Oct 15.


Lysobacter panacihumi sp. nov., isolated from ginseng cultivated soil.

Huo Y, Kang JP, Hurh J, Han Y, Ahn JC, Mathiyalagan R, Piao C, Yang DC.

J Microbiol. 2018 Oct;56(10):748-752. doi: 10.1007/s12275-018-8202-4. Epub 2018 Sep 28.


Rhizobium panacihumi sp. nov., an isolate from ginseng-cultivated soil, as a potential plant growth promoting bacterium.

Kang JP, Huo Y, Kim YJ, Ahn JC, Hurh J, Yang DU, Yang DC.

Arch Microbiol. 2019 Jan;201(1):99-105. doi: 10.1007/s00203-018-1578-z. Epub 2018 Sep 27.


Rhodanobacter ginsengiterrae sp. nov., an antagonistic bacterium against root rot fungal pathogen Fusarium solani, isolated from ginseng rhizospheric soil.

Huo Y, Kang JP, Park JK, Li J, Chen L, Yang DC.

Arch Microbiol. 2018 Dec;200(10):1457-1463. doi: 10.1007/s00203-018-1560-9. Epub 2018 Aug 16.


A Growth-Promoting Bacteria, Paenibacillus yonginensis DCY84T Enhanced Salt Stress Tolerance by Activating Defense-Related Systems in Panax ginseng.

Sukweenadhi J, Balusamy SR, Kim YJ, Lee CH, Kim YJ, Koh SC, Yang DC.

Front Plant Sci. 2018 Jul 23;9:813. doi: 10.3389/fpls.2018.00813. eCollection 2018.


Applications of Panax ginseng leaves-mediated gold nanoparticles in cosmetics relation to antioxidant, moisture retention, and whitening effect on B16BL6 cells.

Jiménez-Pérez ZE, Singh P, Kim YJ, Mathiyalagan R, Kim DH, Lee MH, Yang DC.

J Ginseng Res. 2018 Jul;42(3):327-333. doi: 10.1016/j.jgr.2017.04.003. Epub 2017 Apr 21.


Paraburkholderia panacihumi sp. nov., an isolate from ginseng-cultivated soil, is antagonistic against root rot fungal pathogen.

Huo Y, Kang JP, Kim YJ, Yang DC.

Arch Microbiol. 2018 Oct;200(8):1151-1158. doi: 10.1007/s00203-018-1530-2. Epub 2018 Jun 5.


Ginsenoside Rg5: Rk1 Exerts an Anti-obesity Effect on 3T3-L1 Cell Line by the Downregulation of PPARγ and CEBPα.

Yesmin Simu S, Ahn S, Castro-Aceituno V, Yang DC.

Iran J Biotechnol. 2017 Dec 29;15(4):252-259. doi: 10.15171/ijb.1517. eCollection 2017.


Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions.

Mohanan P, Subramaniyam S, Mathiyalagan R, Yang DC.

J Ginseng Res. 2018 Apr;42(2):123-132. doi: 10.1016/j.jgr.2017.01.008. Epub 2017 Jan 19. Review.


Paenibacillus panacihumi sp. nov., a potential plant growth-promoting bacterium isolated from ginseng-cultivated soil.

Kim CG, Kang JP, Huo Y, Chokkalingam M, Kim YJ, Kim DH, Yang DC.

Arch Microbiol. 2018 Sep;200(7):1049-1055. doi: 10.1007/s00203-018-1517-z. Epub 2018 Apr 20.


Genome and evolution of the shade-requiring medicinal herb Panax ginseng.

Kim NH, Jayakodi M, Lee SC, Choi BS, Jang W, Lee J, Kim HH, Waminal NE, Lakshmanan M, van Nguyen B, Lee YS, Park HS, Koo HJ, Park JY, Perumal S, Joh HJ, Lee H, Kim J, Kim IS, Kim K, Koduru L, Kang KB, Sung SH, Yu Y, Park DS, Choi D, Seo E, Kim S, Kim YC, Hyun DY, Park YI, Kim C, Lee TH, Kim HU, Soh MS, Lee Y, In JG, Kim HS, Kim YM, Yang DC, Wing RA, Lee DY, Paterson AH, Yang TJ.

Plant Biotechnol J. 2018 Nov;16(11):1904-1917. doi: 10.1111/pbi.12926. Epub 2018 May 25.


Expression and functional analysis of three nicosulfuron-degrading enzymes from Bacillus subtilis YB1.

Zhang Z, Zhang Y, Yang DC, Zhang JL.

J Environ Sci Health B. 2018;53(7):476-485. doi: 10.1080/03601234.2018.1455344. Epub 2018 Mar 29.


Rhizome of Anemarrhena asphodeloides as mediators of the eco-friendly synthesis of silver and gold spherical, face-centred cubic nanocrystals and its anti-migratory and cytotoxic potential in normal and cancer cell lines.

Lee HA, Castro-Aceituno V, Abbai R, Moon SS, Kim YJ, Simu SY, Yang DC.

Artif Cells Nanomed Biotechnol. 2018;46(sup2):285-294. doi: 10.1080/21691401.2018.1457038. Epub 2018 Mar 29.


QMCPACK: an open source ab initio quantum Monte Carlo package for the electronic structure of atoms, molecules and solids.

Kim J, Baczewski AT, Beaudet TD, Benali A, Bennett MC, Berrill MA, Blunt NS, Borda EJL, Casula M, Ceperley DM, Chiesa S, Clark BK, Clay RC, Delaney KT, Dewing M, Esler KP, Hao H, Heinonen O, Kent PRC, Krogel JT, Kylänpää I, Li YW, Lopez MG, Luo Y, Malone FD, Martin RM, Mathuriya A, McMinis J, Melton CA, Mitas L, Morales MA, Neuscamman E, Parker WD, Pineda Flores SD, Romero NA, Rubenstein BM, Shea JAR, Shin H, Shulenburger L, Tillack AF, Townsend JP, Tubman NM, Van Der Goetz B, Vincent JE, Yang DC, Yang Y, Zhang S, Zhao L.

J Phys Condens Matter. 2018 May 16;30(19):195901. doi: 10.1088/1361-648X/aab9c3. Epub 2018 Mar 27.


Anisotropic and amphoteric characteristics of diverse carbenes.

Kim DY, Yang DC, Madridejos JML, Hajibabaei A, Baig C, Kim KS.

Phys Chem Chem Phys. 2018 May 23;20(20):13722-13733. doi: 10.1039/C8CP00457A.


In vitro evaluation of the potential therapeutic role of Dendropanax morbifera extract in ameliorating osteoporosis and resultant bone impairment using MC3T3-E1 cells.

Yang DU, Siddiqi MH, Ahn S, Kang S, Noh HY, Yang DC.

In Vitro Cell Dev Biol Anim. 2018 May;54(5):346-354. doi: 10.1007/s11626-018-0242-x. Epub 2018 Mar 20.


Socioeconomic Inequality in One-Year Mortality of Elderly People with Hip Fracture in Taiwan.

Hsu IL, Chang CM, Yang DC, Chang YH, Li CC, Hu SC, Li CY.

Int J Environ Res Public Health. 2018 Feb 16;15(2). pii: E352. doi: 10.3390/ijerph15020352.


Rare ginsenoside Ia synthesized from F1 by cloning and overexpression of the UDP-glycosyltransferase gene from Bacillus subtilis: synthesis, characterization, and in vitro melanogenesis inhibition activity in BL6B16 cells.

Wang DD, Jin Y, Wang C, Kim YJ, Perez ZEJ, Baek NI, Mathiyalagan R, Markus J, Yang DC.

J Ginseng Res. 2018 Jan;42(1):42-49. doi: 10.1016/j.jgr.2016.12.009. Epub 2016 Dec 24.


Cylindrocarpon destructans/Ilyonectria radicicola-species complex: Causative agent of ginseng root-rot disease and rusty symptoms.

Farh ME, Kim YJ, Kim YJ, Yang DC.

J Ginseng Res. 2018 Jan;42(1):9-15. doi: 10.1016/j.jgr.2017.01.004. Epub 2017 Jan 16. Review.


Caspase-3/MAPK pathways as main regulators of the apoptotic effect of the phyto-mediated synthesized silver nanoparticle from dried stem of Eleutherococcus senticosus in human cancer cells.

Kim CG, Castro-Aceituno V, Abbai R, Lee HA, Simu SY, Han Y, Hurh J, Kim YJ, Yang DC.

Biomed Pharmacother. 2018 Mar;99:128-133. doi: 10.1016/j.biopha.2018.01.050. Epub 2018 Jan 10.


Gold nanoflowers synthesized using Acanthopanacis cortex extract inhibit inflammatory mediators in LPS-induced RAW264.7 macrophages via NF-κB and AP-1 pathways.

Ahn S, Singh P, Jang M, Kim YJ, Castro-Aceituno V, Simu SY, Kim YJ, Yang DC.

Colloids Surf B Biointerfaces. 2018 Feb 1;162:398-404. doi: 10.1016/j.colsurfb.2017.11.037. Epub 2017 Nov 17.


In vitro anti-inflammatory activity of spherical silver nanoparticles and monodisperse hexagonal gold nanoparticles by fruit extract of Prunus serrulata: a green synthetic approach.

Singh P, Ahn S, Kang JP, Veronika S, Huo Y, Singh H, Chokkaligam M, El-Agamy Farh M, Aceituno VC, Kim YJ, Yang DC.

Artif Cells Nanomed Biotechnol. 2018 Dec;46(8):2022-2032. doi: 10.1080/21691401.2017.1408117. Epub 2017 Nov 30.


Metabolic dynamics and physiological adaptation of Panax ginseng during development.

Kim YJ, Joo SC, Shi J, Hu C, Quan S, Hu J, Sukweenadhi J, Mohanan P, Yang DC, Zhang D.

Plant Cell Rep. 2018 Mar;37(3):393-410. doi: 10.1007/s00299-017-2236-7. Epub 2017 Nov 17.


Cigarette Smoke Regulates the Competitive Interactions between NRF2 and BACH1 for Heme Oxygenase-1 Induction.

Chang WH, Thai P, Xu J, Yang DC, Wu R, Chen CH.

Int J Mol Sci. 2017 Nov 10;18(11). pii: E2386. doi: 10.3390/ijms18112386.


The avian egg exhibits general allometric invariances in mechanical design.

Juang JY, Chen PY, Yang DC, Wu SP, Yen A, Hsieh HI.

Sci Rep. 2017 Oct 27;7(1):14205. doi: 10.1038/s41598-017-14552-0.


Rattling the border wall: Pathophysiological implications of functional and proteomic venom variation between Mexican and US subspecies of the desert rattlesnake Crotalus scutulatus.

Dobson J, Yang DC, Op den Brouw B, Cochran C, Huynh T, Kurrupu S, Sánchez EE, Massey DJ, Baumann K, Jackson TNW, Nouwens A, Josh P, Neri-Castro E, Alagón A, Hodgson WC, Fry BG.

Comp Biochem Physiol C Toxicol Pharmacol. 2018 Feb;205:62-69. doi: 10.1016/j.cbpc.2017.10.008. Epub 2017 Oct 24.

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