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Items: 1 to 50 of 149

1.

Outcomes of controlled human malaria infection after BCG vaccination.

Walk J, de Bree LCJ, Graumans W, Stoter R, van Gemert GJ, van de Vegte-Bolmer M, Teelen K, Hermsen CC, Arts RJW, Behet MC, Keramati F, Moorlag SJCFM, Yang ASP, van Crevel R, Aaby P, de Mast Q, van der Ven AJAM, Stabell Benn C, Netea MG, Sauerwein RW.

Nat Commun. 2019 Feb 20;10(1):874. doi: 10.1038/s41467-019-08659-3.

2.

Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities.

Jian JW, Chen HS, Chiu YK, Peng HP, Tung CP, Chen IC, Yu CM, Tsou YL, Kuo WY, Hsu HJ, Yang AS.

MAbs. 2019 Feb/Mar;11(2):373-387. doi: 10.1080/19420862.2018.1550320. Epub 2019 Jan 9.

3.

Antibody-drug conjugates with HER2-targeting antibodies from synthetic antibody libraries are highly potent against HER2-positive human gastric tumor in xenograft models.

Kuo WY, Hsu HJ, Wu CY, Chen HS, Chou YC, Tsou YL, Peng HP, Jian JW, Yu CM, Chiu YK, Chen IC, Tung CP, Hsiao M, Lin CL, Wang YA, Wang AH, Yang AS.

MAbs. 2019 Jan;11(1):153-165. doi: 10.1080/19420862.2018.1541370. Epub 2018 Nov 8.

4.

Noninvasive assessment of characteristics of novel anti-HER2 antibodies by molecular imaging in a human gastric cancer xenograft-bearing mouse model.

Kuo WY, Lin JJ, Hsu HJ, Chen HS, Yang AS, Wu CY.

Sci Rep. 2018 Sep 13;8(1):13735. doi: 10.1038/s41598-018-32094-x.

5.

A Plasmodium berghei sporozoite-based vaccination platform against human malaria.

Mendes AM, Machado M, Gonçalves-Rosa N, Reuling IJ, Foquet L, Marques C, Salman AM, Yang ASP, Moser KA, Dwivedi A, Hermsen CC, Jiménez-Díaz B, Viera S, Santos JM, Albuquerque I, Bhatia SN, Bial J, Angulo-Barturen I, Silva JC, Leroux-Roels G, Janse CJ, Khan SM, Mota MM, Sauerwein RW, Prudêncio M.

NPJ Vaccines. 2018 Aug 24;3:33. doi: 10.1038/s41541-018-0068-2. eCollection 2018.

6.

Germline breast cancer susceptibility gene mutations and breast cancer outcomes.

Wang YA, Jian JW, Hung CF, Peng HP, Yang CF, Cheng HS, Yang AS.

BMC Cancer. 2018 Mar 22;18(1):315. doi: 10.1186/s12885-018-4229-5.

7.

Platinum-Catalyzed Allylation of 2,3-Disubstituted Indoles with Allylic Acetates.

Peng BJ, Wu WT, Yang AS.

Molecules. 2017 Nov 29;22(12). pii: E2097. doi: 10.3390/molecules22122097.

8.

High throughput discovery of influenza virus neutralizing antibodies from phage-displayed synthetic antibody libraries.

Chen IC, Chiu YK, Yu CM, Lee CC, Tung CP, Tsou YL, Huang YJ, Lin CL, Chen HS, Wang AH, Yang AS.

Sci Rep. 2017 Oct 31;7(1):14455. doi: 10.1038/s41598-017-14823-w.

9.

Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts.

Lopaticki S, Yang ASP, John A, Scott NE, Lingford JP, O'Neill MT, Erickson SM, McKenzie NC, Jennison C, Whitehead LW, Douglas DN, Kneteman NM, Goddard-Borger ED, Boddey JA.

Nat Commun. 2017 Sep 15;8(1):561. doi: 10.1038/s41467-017-00571-y.

10.

Impact of Chromosomal Rearrangement upon DNA Methylation Patterns in Leukemia.

Byun HM, Eshaghian S, Douer D, Trent J, Garcia-Manero G, Bhatia R, Siegmund K, Yang AS.

Open Med (Wars). 2017 May 4;12:76-85. doi: 10.1515/med-2017-0014. eCollection 2017.

11.

Phase I Study of Fenretinide Delivered Intravenously in Patients with Relapsed or Refractory Hematologic Malignancies: A California Cancer Consortium Trial.

Mohrbacher AM, Yang AS, Groshen S, Kummar S, Gutierrez ME, Kang MH, Tsao-Wei D, Reynolds CP, Newman EM, Maurer BJ.

Clin Cancer Res. 2017 Aug 15;23(16):4550-4555. doi: 10.1158/1078-0432.CCR-17-0234. Epub 2017 Apr 18.

12.

AMA1 and MAEBL are important for Plasmodium falciparum sporozoite infection of the liver.

Yang ASP, Lopaticki S, O'Neill MT, Erickson SM, Douglas DN, Kneteman NM, Boddey JA.

Cell Microbiol. 2017 Sep;19(9). doi: 10.1111/cmi.12745. Epub 2017 May 18.

PMID:
28371168
13.

Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice.

Yang ASP, O'Neill MT, Jennison C, Lopaticki S, Allison CC, Armistead JS, Erickson SM, Rogers KL, Ellisdon AM, Whisstock JC, Tweedell RE, Dinglasan RR, Douglas DN, Kneteman NM, Boddey JA.

Cell Rep. 2017 Mar 28;18(13):3105-3116. doi: 10.1016/j.celrep.2017.03.017.

14.

Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1.

Kwong PD, Chuang GY, DeKosky BJ, Gindin T, Georgiev IS, Lemmin T, Schramm CA, Sheng Z, Soto C, Yang AS, Mascola JR, Shapiro L.

Immunol Rev. 2017 Jan;275(1):108-128. doi: 10.1111/imr.12480. Review.

15.

Molecular mechanisms of host cell traversal by malaria sporozoites.

Yang AS, Boddey JA.

Int J Parasitol. 2017 Feb;47(2-3):129-136. doi: 10.1016/j.ijpara.2016.09.002. Epub 2016 Nov 5. Review.

PMID:
27825827
16.

High throughput cytotoxicity screening of anti-HER2 immunotoxins conjugated with antibody fragments from phage-displayed synthetic antibody libraries.

Hou SC, Chen HS, Lin HW, Chao WT, Chen YS, Fu CY, Yu CM, Huang KF, Wang AH, Yang AS.

Sci Rep. 2016 Aug 23;6:31878. doi: 10.1038/srep31878.

17.

Predicting Ligand Binding Sites on Protein Surfaces by 3-Dimensional Probability Density Distributions of Interacting Atoms.

Jian JW, Elumalai P, Pitti T, Wu CY, Tsai KC, Chang JY, Peng HP, Yang AS.

PLoS One. 2016 Aug 11;11(8):e0160315. doi: 10.1371/journal.pone.0160315. eCollection 2016.

18.

Klippel-Feil syndrome associated with Pierre Robin sequence and mandibular duplication.

Yang AS, Al-Ani SA.

J Plast Reconstr Aesthet Surg. 2016 Aug;69(8):1155-6. doi: 10.1016/j.bjps.2016.04.020. Epub 2016 May 13. No abstract available.

PMID:
27236503
19.

The failure of epigenetic combination therapy for cancer and what it might be telling us about DNA methylation inhibitors.

Yang AS, Yang BJ.

Epigenomics. 2016 Jan;8(1):9-12. doi: 10.2217/epi.15.94. Epub 2015 Dec 23. No abstract available.

PMID:
26698294
20.

Discovering neutralizing antibodies targeting the stem epitope of H1N1 influenza hemagglutinin with synthetic phage-displayed antibody libraries.

Tung CP, Chen IC, Yu CM, Peng HP, Jian JW, Ma SH, Lee YC, Jan JT, Yang AS.

Sci Rep. 2015 Oct 12;5:15053. doi: 10.1038/srep15053.

21.

Predominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigens.

Chen HS, Hou SC, Jian JW, Goh KS, Shen ST, Lee YC, You JJ, Peng HP, Kuo WC, Chen ST, Peng MC, Wang AH, Yu CM, Chen IC, Tung CP, Chen TH, Ping Chiu K, Ma C, Yuan Wu C, Lin SW, Yang AS.

Sci Rep. 2015 Jul 23;5:12411. doi: 10.1038/srep12411.

22.

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.

Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS, Louder MK, McKee K, O'Dell S, Schmidt SD, Tran L, Yang Z, Druz A, Luongo TS, Moquin S, Srivatsan S, Yang Y, Zhang B, Zheng A, Pancera M, Kirys T, Georgiev IS, Gindin T, Peng HP, Yang AS; NISC Comparative Sequencing Program, Mullikin JC, Gray MD, Stamatatos L, Burton DR, Koff WC, Cohen MS, Haynes BF, Casazza JP, Connors M, Corti D, Lanzavecchia A, Sattentau QJ, Weiss RA, West AP Jr, Bjorkman PJ, Scheid JF, Nussenzweig MC, Shapiro L, Mascola JR, Kwong PD.

Cell. 2015 Jun 4;161(6):1280-92. doi: 10.1016/j.cell.2015.05.007. Epub 2015 May 21.

23.

Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial.

Weber JS, D'Angelo SP, Minor D, Hodi FS, Gutzmer R, Neyns B, Hoeller C, Khushalani NI, Miller WH Jr, Lao CD, Linette GP, Thomas L, Lorigan P, Grossmann KF, Hassel JC, Maio M, Sznol M, Ascierto PA, Mohr P, Chmielowski B, Bryce A, Svane IM, Grob JJ, Krackhardt AM, Horak C, Lambert A, Yang AS, Larkin J.

Lancet Oncol. 2015 Apr;16(4):375-84. doi: 10.1016/S1470-2045(15)70076-8. Epub 2015 Mar 18.

PMID:
25795410
24.

High prevalence of respiratory muscle weakness in hospitalized acute heart failure elderly patients.

Verissimo P, Casalaspo TJ, Gonçalves LH, Yang AS, Eid RC, Timenetsky KT.

PLoS One. 2015 Feb 11;10(2):e0118218. doi: 10.1371/journal.pone.0118218. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0124855.

25.

Development of romiplostim: a novel engineered peptibody.

Yang AS.

Semin Hematol. 2015 Jan;52(1):12-5. doi: 10.1053/j.seminhematol.2014.10.007. Epub 2014 Oct 31. Review.

PMID:
25578414
27.

Relationship of different platelet response criteria and patient outcomes in a romiplostim myelodysplastic syndromes trial.

Platzbecker U, Sekeres MA, Kantarjian H, Giagounidis A, Mufti GJ, Jia C, Yang AS, Fenaux P.

Leukemia. 2014 Dec;28(12):2418-21. doi: 10.1038/leu.2014.253. Epub 2014 Sep 2. No abstract available.

28.

Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes.

Sekeres MA, Giagounidis A, Kantarjian H, Mufti GJ, Fenaux P, Jia C, Yang AS, Platzbecker U.

Br J Haematol. 2014 Nov;167(3):337-45. doi: 10.1111/bjh.13037. Epub 2014 Jul 14.

PMID:
25039607
29.

Origins of specificity and affinity in antibody-protein interactions.

Peng HP, Lee KH, Jian JW, Yang AS.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):E2656-65. doi: 10.1073/pnas.1401131111. Epub 2014 Jun 17.

30.

Prediction of fatty acid-binding residues on protein surfaces with three-dimensional probability distributions of interacting atoms.

Mahalingam R, Peng HP, Yang AS.

Biophys Chem. 2014 Aug;192:10-9. doi: 10.1016/j.bpc.2014.05.002. Epub 2014 May 29.

PMID:
24934883
31.

Analysis of prostate-specific antigen transcripts in chimpanzees, cynomolgus monkeys, baboons, and African green monkeys.

Mubiru JN, Yang AS, Olsen C, Nayak S, Livi CB, Dick EJ Jr, Owston M, Garcia-Forey M, Shade RE, Rogers J.

PLoS One. 2014 Apr 14;9(4):e94522. doi: 10.1371/journal.pone.0094522. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e106018.

32.

Results of a randomized, double-blind study of romiplostim versus placebo in patients with low/intermediate-1-risk myelodysplastic syndrome and thrombocytopenia.

Giagounidis A, Mufti GJ, Fenaux P, Sekeres MA, Szer J, Platzbecker U, Kuendgen A, Gaidano G, Wiktor-Jedrzejczak W, Hu K, Woodard P, Yang AS, Kantarjian HM.

Cancer. 2014 Jun 15;120(12):1838-46. doi: 10.1002/cncr.28663. Epub 2014 Apr 4.

33.

Loop-sequence features and stability determinants in antibody variable domains by high-throughput experiments.

Chang HJ, Jian JW, Hsu HJ, Lee YC, Chen HS, You JJ, Hou SC, Shao CY, Chen YJ, Chiu KP, Peng HP, Lee KH, Yang AS.

Structure. 2014 Jan 7;22(1):9-21. doi: 10.1016/j.str.2013.10.005. Epub 2013 Nov 21.

34.

Antibody variable domain interface and framework sequence requirements for stability and function by high-throughput experiments.

Hsu HJ, Lee KH, Jian JW, Chang HJ, Yu CM, Lee YC, Chen IC, Peng HP, Wu CY, Huang YF, Shao CY, Chiu KP, Yang AS.

Structure. 2014 Jan 7;22(1):22-34. doi: 10.1016/j.str.2013.10.006. Epub 2013 Nov 21.

35.

Prediction of FMN-binding residues with three-dimensional probability distributions of interacting atoms on protein surfaces.

Mahalingam R, Peng HP, Yang AS.

J Theor Biol. 2014 Feb 21;343:154-61. doi: 10.1016/j.jtbi.2013.10.020. Epub 2013 Nov 7.

PMID:
24211525
36.

Substrate phage display for protease substrate sequence characterization: bovine factor Xa as a model system.

Hsu HJ, Yang AS.

Methods Mol Biol. 2014;1088:107-24. doi: 10.1007/978-1-62703-673-3_8.

PMID:
24146400
37.

Design of phage-displayed cystine-stabilized mini-protein libraries for proteinaceous binder engineering.

Chang HJ, Yang AS.

Methods Mol Biol. 2014;1088:1-17. doi: 10.1007/978-1-62703-673-3_1.

PMID:
24146393
38.

Targeted 13C enrichment of lipid and protein pools in the body reveals circadian changes in oxidative fuel mixture during prolonged fasting: a case study using Japanese quail.

McCue MD, Amaya JA, Yang AS, Erhardt EB, Wolf BO, Hanson DT.

Comp Biochem Physiol A Mol Integr Physiol. 2013 Dec;166(4):546-54. doi: 10.1016/j.cbpa.2013.08.009. Epub 2013 Aug 27.

PMID:
23988480
39.
40.

Amino acid substitutions of MagA in Klebsiella pneumoniae affect the biosynthesis of the capsular polysaccharide.

Lin TL, Yang FL, Yang AS, Peng HP, Li TL, Tsai MD, Wu SH, Wang JT.

PLoS One. 2012;7(10):e46783. doi: 10.1371/journal.pone.0046783. Epub 2012 Oct 31.

41.

Black sentinel lymph node and 'scary stickers'.

Yang AS, Creagh TA.

J Plast Reconstr Aesthet Surg. 2013 Apr;66(4):558-60. doi: 10.1016/j.bjps.2012.08.021. Epub 2012 Sep 24.

PMID:
23010587
42.

A randomized controlled trial of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving decitabine.

Greenberg PL, Garcia-Manero G, Moore M, Damon L, Roboz G, Hu K, Yang AS, Franklin J.

Leuk Lymphoma. 2013 Feb;54(2):321-8. doi: 10.3109/10428194.2012.713477. Epub 2012 Nov 15.

PMID:
22906162
43.

Prediction of carbohydrate binding sites on protein surfaces with 3-dimensional probability density distributions of interacting atoms.

Tsai KC, Jian JW, Yang EW, Hsu PC, Peng HP, Chen CT, Chen JB, Chang JY, Hsu WL, Yang AS.

PLoS One. 2012;7(7):e40846. doi: 10.1371/journal.pone.0040846. Epub 2012 Jul 25.

44.

Protein-protein interaction site predictions with three-dimensional probability distributions of interacting atoms on protein surfaces.

Chen CT, Peng HP, Jian JW, Tsai KC, Chang JY, Yang EW, Chen JB, Ho SY, Hsu WL, Yang AS.

PLoS One. 2012;7(6):e37706. doi: 10.1371/journal.pone.0037706. Epub 2012 Jun 6.

45.

An innovative numerical approach to resolve the pulse wave velocity in a healthy thoracic aorta model.

Yang AS, Wen CY, Tseng LY, Chiang CC, Tseng WY, Yu HY.

Comput Methods Biomech Biomed Engin. 2014 Apr;17(5):461-73. doi: 10.1080/10255842.2012.691476. Epub 2012 Jun 1.

PMID:
22657104
46.

Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface.

Yu CM, Peng HP, Chen IC, Lee YC, Chen JB, Tsai KC, Chen CT, Chang JY, Yang EW, Hsu PC, Jian JW, Hsu HJ, Chang HJ, Hsu WL, Huang KF, Ma AC, Yang AS.

PLoS One. 2012;7(3):e33340. doi: 10.1371/journal.pone.0033340. Epub 2012 Mar 22.

47.

Immunologic correlates of the abscopal effect in a patient with melanoma.

Postow MA, Callahan MK, Barker CA, Yamada Y, Yuan J, Kitano S, Mu Z, Rasalan T, Adamow M, Ritter E, Sedrak C, Jungbluth AA, Chua R, Yang AS, Roman RA, Rosner S, Benson B, Allison JP, Lesokhin AM, Gnjatic S, Wolchok JD.

N Engl J Med. 2012 Mar 8;366(10):925-31. doi: 10.1056/NEJMoa1112824.

48.

Mono-allelic retrotransposon insertion addresses epigenetic transcriptional repression in human genome.

Byun HM, Heo K, Mitchell KJ, Yang AS.

J Biomed Sci. 2012 Feb 2;19:13. doi: 10.1186/1423-0127-19-13.

49.

A practical synthesis of zanamivir phosphonate congeners with potent anti-influenza activity.

Shie JJ, Fang JM, Lai PT, Wen WH, Wang SY, Cheng YS, Tsai KC, Yang AS, Wong CH.

J Am Chem Soc. 2011 Nov 9;133(44):17959-65. doi: 10.1021/ja207892q. Epub 2011 Oct 14.

PMID:
21942552
50.

E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors.

Shen YF, Chen YH, Chu SY, Lin MI, Hsu HT, Wu PY, Wu CJ, Liu HW, Lin FY, Lin G, Hsu PH, Yang AS, Cheng YS, Wu YT, Wong CH, Tsai MD.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16515-20. doi: 10.1073/pnas.1113107108. Epub 2011 Sep 19.

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