Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 62

1.

CD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression.

Cano-Crespo S, Chillarón J, Junza A, Fernández-Miranda G, García J, Polte C, R de la Ballina L, Ignatova Z, Yanes Ó, Zorzano A, Stephan-Otto Attolini C, Palacín M.

Sci Rep. 2019 Oct 1;9(1):14065. doi: 10.1038/s41598-019-50547-9.

2.

Epigenetic Regulation at the Interplay Between Gut Microbiota and Host Metabolism.

Miro-Blanch J, Yanes O.

Front Genet. 2019 Jul 5;10:638. doi: 10.3389/fgene.2019.00638. eCollection 2019.

3.

Dysfunctional LAT2 Amino Acid Transporter Is Associated With Cataract in Mouse and Humans.

Knöpfel EB, Vilches C, Camargo SMR, Errasti-Murugarren E, Stäubli A, Mayayo C, Munier FL, Miroshnikova N, Poncet N, Junza A, Bhattacharya SS, Prat E, Berry V, Berger W, Heon E, Moore AT, Yanes Ó, Nunes V, Palacín M, Verrey F, Kloeckener-Gruissem B.

Front Physiol. 2019 Jun 4;10:688. doi: 10.3389/fphys.2019.00688. eCollection 2019.

4.

Plasma glucose, triglycerides, VLDL, leptin and resistin levels as potential biomarkers for myocardial fat in mice.

Rodríguez-Calvo R, Samino S, Guaita-Esteruelas S, Martínez-Micaelo N, Heras M, Girona J, Yanes O, Correig X, Masana L.

Clin Investig Arterioscler. 2019 Jun 17. pii: S0214-9168(19)30064-6. doi: 10.1016/j.arteri.2019.05.001. [Epub ahead of print] English, Spanish.

PMID:
31221535
5.

Fatty acid binding protein 4 (FABP4) as a potential biomarker reflecting myocardial lipid storage in type 2 diabetes.

Rodríguez-Calvo R, Girona J, Rodríguez M, Samino S, Barroso E, de Gonzalo-Calvo D, Guaita-Esteruelas S, Heras M, van der Meer RW, Lamb HJ, Yanes O, Correig X, Llorente-Cortés V, Vázquez-Carrera M, Masana L.

Metabolism. 2019 Jul;96:12-21. doi: 10.1016/j.metabol.2019.04.007. Epub 2019 Apr 15.

PMID:
30999003
6.

CliqueMS: a computational tool for annotating in-source metabolite ions from LC-MS untargeted metabolomics data based on a coelution similarity network.

Senan O, Aguilar-Mogas A, Navarro M, Capellades J, Noon L, Burks D, Yanes O, Guimerà R, Sales-Pardo M.

Bioinformatics. 2019 Oct 15;35(20):4089-4097. doi: 10.1093/bioinformatics/btz207.

PMID:
30903689
7.

Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.

Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R, Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, Whittington HJ, Lake HA, Zervou S, Lygate CA, Kessler BM, Harris AL.

Mol Cancer Res. 2019 Jul;17(7):1531-1544. doi: 10.1158/1541-7786.MCR-18-0315. Epub 2019 Mar 18.

PMID:
30885992
8.

Epigenetic loss of the endoplasmic reticulum-associated degradation inhibitor SVIP induces cancer cell metabolic reprogramming.

Llinàs-Arias P, Rosselló-Tortella M, López-Serra P, Pérez-Salvia M, Setién F, Marin S, Muñoz JP, Junza A, Capellades J, Calleja-Cervantes ME, Ferreira HJ, de Moura MC, Srbic M, Martínez-Cardús A, de la Torre C, Villanueva A, Cascante M, Yanes O, Zorzano A, Moutinho C, Esteller M.

JCI Insight. 2019 Mar 7;5. pii: 125888. doi: 10.1172/jci.insight.125888.

9.

FELLA: an R package to enrich metabolomics data.

Picart-Armada S, Fernández-Albert F, Vinaixa M, Yanes O, Perera-Lluna A.

BMC Bioinformatics. 2018 Dec 22;19(1):538. doi: 10.1186/s12859-018-2487-5.

10.

Assessing the potential of sputtered gold nanolayers in mass spectrometry imaging for metabolomics applications.

Ràfols P, Vilalta D, Torres S, Calavia R, Heijs B, McDonnell LA, Brezmes J, Del Castillo E, Yanes O, Ramírez N, Correig X.

PLoS One. 2018 Dec 12;13(12):e0208908. doi: 10.1371/journal.pone.0208908. eCollection 2018.

11.

Mind the Gap: Mapping Mass Spectral Databases in Genome-Scale Metabolic Networks Reveals Poorly Covered Areas.

Frainay C, Schymanski EL, Neumann S, Merlet B, Salek RM, Jourdan F, Yanes O.

Metabolites. 2018 Sep 15;8(3). pii: E51. doi: 10.3390/metabo8030051.

12.

Lifestyle Intervention Decreases Urine Trimethylamine N-Oxide Levels in Prepubertal Children with Obesity.

Leal-Witt MJ, Llobet M, Samino S, Castellano P, Cuadras D, Jimenez-Chillaron JC, Yanes O, Ramon-Krauel M, Lerin C.

Obesity (Silver Spring). 2018 Oct;26(10):1603-1610. doi: 10.1002/oby.22271. Epub 2018 Sep 11.

13.

Epigenetic programming at the Mogat1 locus may link neonatal overnutrition with long-term hepatic steatosis and insulin resistance.

Ramon-Krauel M, Pentinat T, Bloks VW, Cebrià J, Ribo S, Pérez-Wienese R, Vilà M, Palacios-Marin I, Fernández-Pérez A, Vallejo M, Téllez N, Rodríguez MÀ, Yanes O, Lerin C, Díaz R, Plosch T, Tietge UJF, Jimenez-Chillaron JC.

FASEB J. 2018 May 29:fj201700717RR. doi: 10.1096/fj.201700717RR. [Epub ahead of print]

PMID:
29812971
14.

Novel automated workflow for spectral alignment and mass calibration in MS imaging using a sputtered Ag nanolayer.

Ràfols P, Castillo ED, Yanes O, Brezmes J, Correig X.

Anal Chim Acta. 2018 Aug 31;1022:61-69. doi: 10.1016/j.aca.2018.03.031. Epub 2018 Apr 6.

PMID:
29729739
15.

EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation.

Silva J, Aivio S, Knobel PA, Bailey LJ, Casali A, Vinaixa M, Garcia-Cao I, Coyaud É, Jourdain AA, Pérez-Ferreros P, Rojas AM, Antolin-Fontes A, Samino-Gené S, Raught B, González-Reyes A, Ribas de Pouplana L, Doherty AJ, Yanes O, Stracker TH.

Nat Cell Biol. 2018 Feb;20(2):162-174. doi: 10.1038/s41556-017-0016-9. Epub 2018 Jan 15.

16.

Metabolomics reveals novel blood plasma biomarkers associated to the BRCA1-mutated phenotype of human breast cancer.

Roig B, Rodríguez-Balada M, Samino S, Lam EW, Guaita-Esteruelas S, Gomes AR, Correig X, Borràs J, Yanes O, Gumà J.

Sci Rep. 2017 Dec 19;7(1):17831. doi: 10.1038/s41598-017-17897-8.

17.

Null diffusion-based enrichment for metabolomics data.

Picart-Armada S, Fernández-Albert F, Vinaixa M, Rodríguez MA, Aivio S, Stracker TH, Yanes O, Perera-Lluna A.

PLoS One. 2017 Dec 6;12(12):e0189012. doi: 10.1371/journal.pone.0189012. eCollection 2017.

18.

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption.

Posavec Marjanović M, Hurtado-Bagès S, Lassi M, Valero V, Malinverni R, Delage H, Navarro M, Corujo D, Guberovic I, Douet J, Gama-Perez P, Garcia-Roves PM, Ahel I, Ladurner AG, Yanes O, Bouvet P, Suelves M, Teperino R, Pospisilik JA, Buschbeck M.

Nat Struct Mol Biol. 2017 Nov;24(11):902-910. doi: 10.1038/nsmb.3481. Epub 2017 Oct 9.

19.

Role of the Transforming Growth Factor-β in regulating hepatocellular carcinoma oxidative metabolism.

Soukupova J, Malfettone A, Hyroššová P, Hernández-Alvarez MI, Peñuelas-Haro I, Bertran E, Junza A, Capellades J, Giannelli G, Yanes O, Zorzano A, Perales JC, Fabregat I.

Sci Rep. 2017 Oct 2;7(1):12486. doi: 10.1038/s41598-017-12837-y.

20.

Untargeted metabolomics identifies a plasma sphingolipid-related signature associated with lifestyle intervention in prepubertal children with obesity.

Leal-Witt MJ, Ramon-Krauel M, Samino S, Llobet M, Cuadras D, Jimenez-Chillaron JC, Yanes O, Lerin C.

Int J Obes (Lond). 2018 Jan;42(1):72-78. doi: 10.1038/ijo.2017.201. Epub 2017 Aug 17.

PMID:
28947825
21.

rMSI: an R package for MS imaging data handling and visualization.

Ràfols P, Torres S, Ramírez N, Del Castillo E, Yanes O, Brezmes J, Correig X.

Bioinformatics. 2017 Aug 1;33(15):2427-2428. doi: 10.1093/bioinformatics/btx182.

PMID:
28369250
22.

iMet: A Network-Based Computational Tool To Assist in the Annotation of Metabolites from Tandem Mass Spectra.

Aguilar-Mogas A, Sales-Pardo M, Navarro M, Guimerà R, Yanes O.

Anal Chem. 2017 Mar 21;89(6):3474-3482. doi: 10.1021/acs.analchem.6b04512. Epub 2017 Mar 3.

PMID:
28221024
23.

Positional Enrichment by Proton Analysis (PEPA): A One-Dimensional 1 H-NMR Approach for 13 C Stable Isotope Tracer Studies in Metabolomics.

Vinaixa M, Rodríguez MA, Aivio S, Capellades J, Gómez J, Canyellas N, Stracker TH, Yanes O.

Angew Chem Int Ed Engl. 2017 Mar 20;56(13):3531-3535. doi: 10.1002/anie.201611347. Epub 2017 Feb 21.

24.

Metabolic Profiling in Formalin-Fixed and Paraffin-Embedded Prostate Cancer Tissues.

Cacciatore S, Zadra G, Bango C, Penney KL, Tyekucheva S, Yanes O, Loda M.

Mol Cancer Res. 2017 Apr;15(4):439-447. doi: 10.1158/1541-7786.MCR-16-0262. Epub 2017 Jan 10.

25.

Signal preprocessing, multivariate analysis and software tools for MA(LDI)-TOF mass spectrometry imaging for biological applications.

Ràfols P, Vilalta D, Brezmes J, Cañellas N, Del Castillo E, Yanes O, Ramírez N, Correig X.

Mass Spectrom Rev. 2018 May;37(3):281-306. doi: 10.1002/mas.21527. Epub 2016 Nov 9. Review.

PMID:
27862147
26.

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells.

Ratajczak J, Joffraud M, Trammell SA, Ras R, Canela N, Boutant M, Kulkarni SS, Rodrigues M, Redpath P, Migaud ME, Auwerx J, Yanes O, Brenner C, Cantó C.

Nat Commun. 2016 Oct 11;7:13103. doi: 10.1038/ncomms13103.

27.

eRah: A Computational Tool Integrating Spectral Deconvolution and Alignment with Quantification and Identification of Metabolites in GC/MS-Based Metabolomics.

Domingo-Almenara X, Brezmes J, Vinaixa M, Samino S, Ramirez N, Ramon-Krauel M, Lerin C, Díaz M, Ibáñez L, Correig X, Perera-Lluna A, Yanes O.

Anal Chem. 2016 Oct 4;88(19):9821-9829. Epub 2016 Sep 14.

PMID:
27584001
28.

Redundant roles of the phosphatidate phosphatase family in triacylglycerol synthesis in human adipocytes.

Temprano A, Sembongi H, Han GS, Sebastián D, Capellades J, Moreno C, Guardiola J, Wabitsch M, Richart C, Yanes O, Zorzano A, Carman GM, Siniossoglou S, Miranda M.

Diabetologia. 2016 Sep;59(9):1985-94. doi: 10.1007/s00125-016-4018-0. Epub 2016 Jun 25.

29.

ADP-ribose-derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling.

Wright RH, Lioutas A, Le Dily F, Soronellas D, Pohl A, Bonet J, Nacht AS, Samino S, Font-Mateu J, Vicent GP, Wierer M, Trabado MA, Schelhorn C, Carolis C, Macias MJ, Yanes O, Oliva B, Beato M.

Science. 2016 Jun 3;352(6290):1221-5. doi: 10.1126/science.aad9335.

30.

FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth.

Slebe F, Rojo F, Vinaixa M, García-Rocha M, Testoni G, Guiu M, Planet E, Samino S, Arenas EJ, Beltran A, Rovira A, Lluch A, Salvatella X, Yanes O, Albanell J, Guinovart JJ, Gomis RR.

Nat Commun. 2016 Apr 5;7:11199. doi: 10.1038/ncomms11199.

31.

Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans.

Ceperuelo-Mallafré V, Ejarque M, Serena C, Duran X, Montori-Grau M, Rodríguez MA, Yanes O, Núñez-Roa C, Roche K, Puthanveetil P, Garrido-Sánchez L, Saez E, Tinahones FJ, Garcia-Roves PM, Gómez-Foix AM, Saltiel AR, Vendrell J, Fernández-Veledo S.

Mol Metab. 2015 Oct 16;5(1):5-18. doi: 10.1016/j.molmet.2015.10.001. eCollection 2016 Jan.

32.

Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: "Herniated" HDL, a common feature in diabetes.

Amigó N, Mallol R, Heras M, Martínez-Hervás S, Blanco Vaca F, Escolà-Gil JC, Plana N, Yanes Ó, Masana L, Correig X.

Sci Rep. 2016 Jan 18;6:19249. doi: 10.1038/srep19249.

33.

geoRge: A Computational Tool To Detect the Presence of Stable Isotope Labeling in LC/MS-Based Untargeted Metabolomics.

Capellades J, Navarro M, Samino S, Garcia-Ramirez M, Hernandez C, Simo R, Vinaixa M, Yanes O.

Anal Chem. 2016 Jan 5;88(1):621-8. doi: 10.1021/acs.analchem.5b03628. Epub 2015 Dec 18.

PMID:
26639619
34.

Metabolomics reveals impaired maturation of HDL particles in adolescents with hyperinsulinaemic androgen excess.

Samino S, Vinaixa M, Díaz M, Beltran A, Rodríguez MA, Mallol R, Heras M, Cabre A, Garcia L, Canela N, de Zegher F, Correig X, Ibáñez L, Yanes O.

Sci Rep. 2015 Jun 23;5:11496. doi: 10.1038/srep11496.

35.

Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways.

Valli A, Rodriguez M, Moutsianas L, Fischer R, Fedele V, Huang HL, Van Stiphout R, Jones D, Mccarthy M, Vinaxia M, Igarashi K, Sato M, Soga T, Buffa F, Mccullagh J, Yanes O, Harris A, Kessler B.

Oncotarget. 2015 Feb 10;6(4):1920-41.

36.

Liposcale: a novel advanced lipoprotein test based on 2D diffusion-ordered 1H NMR spectroscopy.

Mallol R, Amigó N, Rodríguez MA, Heras M, Vinaixa M, Plana N, Rock E, Ribalta J, Yanes O, Masana L, Correig X.

J Lipid Res. 2015 Mar;56(3):737-46. doi: 10.1194/jlr.D050120. Epub 2015 Jan 7.

37.

Sample preparation methods for LC-MS-based global aqueous metabolite profiling.

Beltran A, Samino S, Yanes O.

Methods Mol Biol. 2014;1198:75-80. doi: 10.1007/978-1-4939-1258-2_5.

PMID:
25270923
38.

Integrative analysis reveals novel pathways mediating the interaction between adipose tissue and pancreatic islets in obesity in rats.

Malpique R, Figueiredo H, Esteban Y, Rebuffat SA, Hanzu FA, Vinaixa M, Yanes O, Correig X, Barceló-Batllori S, Gasa R, Kalko SG, Gomis R.

Diabetologia. 2014 Jun;57(6):1219-31. doi: 10.1007/s00125-014-3205-0. Epub 2014 Mar 15.

PMID:
24633677
39.

Neurons have an active glycogen metabolism that contributes to tolerance to hypoxia.

Saez I, Duran J, Sinadinos C, Beltran A, Yanes O, Tevy MF, Martínez-Pons C, Milán M, Guinovart JJ.

J Cereb Blood Flow Metab. 2014 Jun;34(6):945-55. doi: 10.1038/jcbfm.2014.33. Epub 2014 Feb 26.

40.

Metabolomics: playing piñata with single cells.

Yanes O.

Nat Chem Biol. 2013 Aug;9(8):471-3. doi: 10.1038/nchembio.1297.

PMID:
23868315
41.

Assessment of compatibility between extraction methods for NMR- and LC/MS-based metabolomics.

Beltran A, Suarez M, Rodríguez MA, Vinaixa M, Samino S, Arola L, Correig X, Yanes O.

Anal Chem. 2012 Jul 17;84(14):5838-44. doi: 10.1021/ac3005567. Epub 2012 Jun 26.

PMID:
22697410
42.

Nanostructure Initiator Mass Spectrometry for tissue imaging in metabolomics: future prospects and perspectives.

Calavia R, Annanouch FE, Correig X, Yanes O.

J Proteomics. 2012 Aug 30;75(16):5061-5068. doi: 10.1016/j.jprot.2012.05.002. Epub 2012 May 9. Review.

PMID:
22580361
43.

Innovation: Metabolomics: the apogee of the omics trilogy.

Patti GJ, Yanes O, Siuzdak G.

Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):263-9. doi: 10.1038/nrm3314. Review.

44.

Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy.

Marchetti V, Yanes O, Aguilar E, Wang M, Friedlander D, Moreno S, Storm K, Zhan M, Naccache S, Nemerow G, Siuzdak G, Friedlander M.

Sci Rep. 2011;1:76. doi: 10.1038/srep00076. Epub 2011 Aug 30.

45.

Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin.

Patti GJ, Yanes O, Shriver LP, Courade JP, Tautenhahn R, Manchester M, Siuzdak G.

Nat Chem Biol. 2012 Jan 22;8(3):232-4. doi: 10.1038/nchembio.767.

46.

A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data.

Vinaixa M, Samino S, Saez I, Duran J, Guinovart JJ, Yanes O.

Metabolites. 2012 Oct 18;2(4):775-95. doi: 10.3390/metabo2040775.

47.

Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy.

Vinaixa M, Rodriguez MA, Samino S, Díaz M, Beltran A, Mallol R, Bladé C, Ibañez L, Correig X, Yanes O.

PLoS One. 2011;6(12):e29052. doi: 10.1371/journal.pone.0029052. Epub 2011 Dec 16.

48.

The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming.

Panopoulos AD, Yanes O, Ruiz S, Kida YS, Diep D, Tautenhahn R, Herrerías A, Batchelder EM, Plongthongkum N, Lutz M, Berggren WT, Zhang K, Evans RM, Siuzdak G, Izpisua Belmonte JC.

Cell Res. 2012 Jan;22(1):168-77. doi: 10.1038/cr.2011.177. Epub 2011 Nov 8.

49.

Expanding coverage of the metabolome for global metabolite profiling.

Yanes O, Tautenhahn R, Patti GJ, Siuzdak G.

Anal Chem. 2011 Mar 15;83(6):2152-61. doi: 10.1021/ac102981k. Epub 2011 Feb 17.

50.

Metabolic oxidation regulates embryonic stem cell differentiation.

Yanes O, Clark J, Wong DM, Patti GJ, Sánchez-Ruiz A, Benton HP, Trauger SA, Desponts C, Ding S, Siuzdak G.

Nat Chem Biol. 2010 Jun;6(6):411-7. doi: 10.1038/nchembio.364. Epub 2010 May 2.

Supplemental Content

Support Center