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High concentrations of trimethylamines in slime glands inhibit skein unraveling in Pacific hagfish.

Jain G, Starksen M, Singh K, Hoang C, Yancey P, McCord C, Fudge DS.

J Exp Biol. 2019 Nov 22;222(Pt 22). pii: jeb213793. doi: 10.1242/jeb.213793.


Modified sites and functional consequences of 4-oxo-2-nonenal adducts in HDL that are elevated in familial hypercholesterolemia.

May-Zhang LS, Yermalitsky V, Melchior JT, Morris J, Tallman KA, Borja MS, Pleasent T, Amarnath V, Song W, Yancey PG, Davidson WS, Linton MF, Davies SS.

J Biol Chem. 2019 Dec 13;294(50):19022-19033. doi: 10.1074/jbc.RA119.009424. Epub 2019 Oct 30.


Unique osmoregulatory morphology in primitive sharks: an intermediate state between holocephalan and derived shark secretory morphology.

Larsen ME, Abel DC, Crane DP, Parker SL, Yancey PH, Keller BA, Grubbs DR.

J Fish Biol. 2019 Nov;95(5):1331-1341. doi: 10.1111/jfb.14139. Epub 2019 Oct 7.


Lipoprotein modulation of proteinuric renal injury.

Tsuchida Y, Zhong J, Otsuka T, Dikalova A, Pastan I, Anantharamaiah GM, Linton MF, Yancey PG, Ikizler TA, Fogo AB, Yang H, Kon V.

Lab Invest. 2019 Jul;99(8):1107-1116. doi: 10.1038/s41374-019-0253-6. Epub 2019 Apr 24.


IL-1 Inhibition and Function of the HDL-Containing Fraction of Plasma in Patients with Stages 3 to 5 CKD.

Hung AM, Tsuchida Y, Nowak KL, Sarkar S, Chonchol M, Whitfield V, Salas N, Dikalova A, Yancey PG, Huang J, Linton MF, Ikizler TA, Kon V.

Clin J Am Soc Nephrol. 2019 May 7;14(5):702-711. doi: 10.2215/CJN.04360418. Epub 2019 Apr 23.


Administration of N-Acyl-Phosphatidylethanolamine Expressing Bacteria to Low Density Lipoprotein Receptor-/- Mice Improves Indices of Cardiometabolic Disease.

May-Zhang LS, Chen Z, Dosoky NS, Yancey PG, Boyd KL, Hasty AH, Linton MF, Davies SS.

Sci Rep. 2019 Jan 23;9(1):420. doi: 10.1038/s41598-018-37373-1.


Myeloid-Specific Deletion of Epsins 1 and 2 Reduces Atherosclerosis by Preventing LRP-1 Downregulation.

Brophy ML, Dong Y, Tao H, Yancey PG, Song K, Zhang K, Wen A, Wu H, Lee Y, Malovichko MV, Sithu SD, Wong S, Yu L, Kocher O, Bischoff J, Srivastava S, Linton MF, Ley K, Chen H.

Circ Res. 2019 Feb 15;124(4):e6-e19. doi: 10.1161/CIRCRESAHA.118.313028.


High-density element concentrations in fish from subtidal to hadal zones of the Pacific Ocean.

Welty CJ, Sousa ML, Dunnivant FM, Yancey PH.

Heliyon. 2018 Oct 9;4(10):e00840. doi: 10.1016/j.heliyon.2018.e00840. eCollection 2018 Oct.


Modification by isolevuglandins, highly reactive ő≥-ketoaldehydes, deleteriously alters high-density lipoprotein structure and function.

May-Zhang LS, Yermalitsky V, Huang J, Pleasent T, Borja MS, Oda MN, Jerome WG, Yancey PG, Linton MF, Davies SS.

J Biol Chem. 2018 Jun 15;293(24):9176-9187. doi: 10.1074/jbc.RA117.001099. Epub 2018 Apr 30.


Chronic kidney disease alters lipid trafficking and inflammatory responses in macrophages: effects of liver X receptor agonism.

Kaseda R, Tsuchida Y, Yang HC, Yancey PG, Zhong J, Tao H, Bian A, Fogo AB, Linton MRF, Fazio S, Ikizler TA, Kon V.

BMC Nephrol. 2018 Jan 27;19(1):17. doi: 10.1186/s12882-018-0814-8.


Osmolyte Adjustments as a Pressure Adaptation in Deep-Sea Chondrichthyan Fishes: An Intraspecific Test in Arctic Skates (Amblyraja hyperborea) along a Depth Gradient.

Yancey PH, Speers-Roesch B, Atchinson S, Reist JD, Majewski AR, Treberg JR.

Physiol Biochem Zool. 2018 Mar/Apr;91(2):788-796. doi: 10.1086/696157.


Distribution, composition and functions of gelatinous tissues in deep-sea fishes.

Gerringer ME, Drazen JC, Linley TD, Summers AP, Jamieson AJ, Yancey PH.

R Soc Open Sci. 2017 Dec 6;4(12):171063. doi: 10.1098/rsos.171063. eCollection 2017 Dec.


Thermal history and gape of individual Mytilus californianus correlate with oxidative damage and thermoprotective osmolytes.

Gleason LU, Miller LP, Winnikoff JR, Somero GN, Yancey PH, Bratz D, Dowd WW.

J Exp Biol. 2017 Nov 15;220(Pt 22):4292-4304. doi: 10.1242/jeb.168450.


Betaine in the Brain: Characterization of Betaine Uptake, its Influence on Other Osmolytes and its Potential Role in Neuroprotection from Osmotic Stress.

Knight LS, Piibe Q, Lambie I, Perkins C, Yancey PH.

Neurochem Res. 2017 Dec;42(12):3490-3503. doi: 10.1007/s11064-017-2397-3. Epub 2017 Sep 16.


SR-BI: A Multifunctional Receptor in Cholesterol Homeostasis and Atherosclerosis.

Linton MF, Tao H, Linton EF, Yancey PG.

Trends Endocrinol Metab. 2017 Jun;28(6):461-472. doi: 10.1016/j.tem.2017.02.001. Epub 2017 Mar 1. Review.


Net cholesterol efflux capacity of HDL enriched serum and coronary atherosclerosis in rheumatoid arthritis.

Ormseth MJ, Yancey PG, Yamamoto S, Oeser AM, Gebretsadik T, Shintani A, Linton MF, Fazio S, Davies SS, Roberts LJ 2nd, Vickers KC, Raggi P, Kon V, Stein CM.

IJC Metab Endocr. 2016 Dec;13:6-11. doi: 10.1016/j.ijcme.2016.08.002. Epub 2016 Aug 28.


Macrophage Apoptosis and Efferocytosis in the Pathogenesis of Atherosclerosis.

Linton MF, Babaev VR, Huang J, Linton EF, Tao H, Yancey PG.

Circ J. 2016 Oct 25;80(11):2259-2268. Epub 2016 Oct 8. Review.


Effect of Drug Therapy on Net Cholesterol Efflux Capacity of High-Density Lipoprotein-Enriched Serum in Rheumatoid Arthritis.

Ormseth MJ, Yancey PG, Solus JF, Bridges SL Jr, Curtis JR, Linton MF, Fazio S, Davies SS, Roberts LJ 2nd, Vickers KC, Kon V, Michael Stein C; TETRAD Investigators.

Arthritis Rheumatol. 2016 Sep;68(9):2099-105. doi: 10.1002/art.39675.


The Role of Lipids and Lipoproteins in Atherosclerosis.

Linton MRF, Yancey PG, Davies SS, Jerome WG, Linton EF, Song WL, Doran AC, Vickers KC.

In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP, editors. Endotext [Internet]. South Dartmouth (MA):, Inc.; 2000-.
2019 Jan 3.


Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype.

Yamamoto S, Zhong J, Yancey PG, Zuo Y, Linton MF, Fazio S, Yang H, Narita I, Kon V.

Atherosclerosis. 2015 Sep;242(1):56-64. doi: 10.1016/j.atherosclerosis.2015.06.055. Epub 2015 Jul 4.


Co-evolution of proteins and solutions: protein adaptation versus cytoprotective micromolecules and their roles in marine organisms.

Yancey PH, Siebenaller JF.

J Exp Biol. 2015 Jun;218(Pt 12):1880-96. doi: 10.1242/jeb.114355. Review.


Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis.

Tao H, Yancey PG, Babaev VR, Blakemore JL, Zhang Y, Ding L, Fazio S, Linton MF.

J Lipid Res. 2015 Aug;56(8):1449-60. doi: 10.1194/jlr.M056689. Epub 2015 Jun 9.


Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts.

Guo L, Chen Z, Amarnath V, Yancey PG, Van Lenten BJ, Savage JR, Fazio S, Linton MF, Davies SS.

Antioxid Redox Signal. 2015 Jun 20;22(18):1633-45. doi: 10.1089/ars.2014.6078. Epub 2015 Mar 18.


Trehalose is a chemical attractant in the establishment of coral symbiosis.

Hagedorn M, Carter V, Zuchowicz N, Phillips M, Penfield C, Shamenek B, Vallen EA, Kleinhans FW, Peterson K, White M, Yancey PH.

PLoS One. 2015 Jan 28;10(1):e0117087. doi: 10.1371/journal.pone.0117087. eCollection 2015.


Macrophage apoAI protects against dyslipidemia-induced dermatitis and atherosclerosis without affecting HDL.

Tavori H, Su YR, Yancey PG, Giunzioni I, Wilhelm AJ, Blakemore JL, Zabalawi M, Linton MF, Sorci-Thomas MG, Fazio S.

J Lipid Res. 2015 Mar;56(3):635-43. doi: 10.1194/jlr.M056408. Epub 2015 Jan 15.


Dysfunctional high-density lipoproteins in children with chronic kidney disease.

Kaseda R, Jabs K, Hunley TE, Jones D, Bian A, Allen RM, Vickers KC, Yancey PG, Linton MF, Fazio S, Kon V.

Metabolism. 2015 Feb;64(2):263-73. doi: 10.1016/j.metabol.2014.10.020. Epub 2014 Oct 25.


Marine fish may be biochemically constrained from inhabiting the deepest ocean depths.

Yancey PH, Gerringer ME, Drazen JC, Rowden AA, Jamieson A.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4461-5. doi: 10.1073/pnas.1322003111. Epub 2014 Mar 3.


Life as a professor at a small liberal arts college.

Sandquist J, Romberg L, Yancey P.

Mol Biol Cell. 2013 Nov;24(21):3285-91. doi: 10.1091/mbc.E13-06-0341.


Seawater acclimation and inositol monophosphatase isoform expression in the European eel (Anguilla anguilla) and Nile tilapia (Orechromis niloticus).

Kalujnaia S, Gellatly SA, Hazon N, Villasenor A, Yancey PH, Cramb G.

Am J Physiol Regul Integr Comp Physiol. 2013 Aug 15;305(4):R369-84. doi: 10.1152/ajpregu.00044.2013. Epub 2013 Jun 5.


Serum proprotein convertase subtilisin/kexin type 9 and cell surface low-density lipoprotein receptor: evidence for a reciprocal regulation.

Tavori H, Fan D, Blakemore JL, Yancey PG, Ding L, Linton MF, Fazio S.

Circulation. 2013 Jun 18;127(24):2403-13. doi: 10.1161/CIRCULATIONAHA.113.001592. Epub 2013 May 20.


Dysfunctional high-density lipoprotein in patients on chronic hemodialysis.

Yamamoto S, Yancey PG, Ikizler TA, Jerome WG, Kaseda R, Cox B, Bian A, Shintani A, Fogo AB, Linton MF, Fazio S, Kon V.

J Am Coll Cardiol. 2012 Dec 11;60(23):2372-9. doi: 10.1016/j.jacc.2012.09.013. Epub 2012 Nov 7.


On the validity of the Trieste flatfish: dispelling the myth.

Jamieson AJ, Yancey PH.

Biol Bull. 2012 Jun;222(3):171-5. No abstract available.


Macrophage polarization by angiotensin II-type 1 receptor aggravates renal injury-acceleration of atherosclerosis.

Yamamoto S, Yancey PG, Zuo Y, Ma LJ, Kaseda R, Fogo AB, Ichikawa I, Linton MF, Fazio S, Kon V.

Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2856-64. doi: 10.1161/ATVBAHA.111.237198. Epub 2011 Oct 6.


Decreasing urea‚ą∂trimethylamine N-oxide ratios with depth in chondrichthyes: a physiological depth limit?

Laxson CJ, Condon NE, Drazen JC, Yancey PH.

Physiol Biochem Zool. 2011 Sep-Oct;84(5):494-505. doi: 10.1086/661774.


Low-density lipoprotein receptor-related protein 1 prevents early atherosclerosis by limiting lesional apoptosis and inflammatory Ly-6Chigh monocytosis: evidence that the effects are not apolipoprotein E dependent.

Yancey PG, Ding Y, Fan D, Blakemore JL, Zhang Y, Ding L, Zhang J, Linton MF, Fazio S.

Circulation. 2011 Jul 26;124(4):454-64. doi: 10.1161/CIRCULATIONAHA.111.032268. Epub 2011 Jul 5.


Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice.

Yamamoto S, Zuo Y, Ma J, Yancey PG, Hunley TE, Motojima M, Fogo AB, Linton MF, Fazio S, Ichikawa I, Kon V.

Nephrol Dial Transplant. 2011 Aug;26(8):2491-7. doi: 10.1093/ndt/gfq759. Epub 2011 Jan 18.


Stabilization and swelling of hagfish slime mucin vesicles.

Herr JE, Winegard TM, O'Donnell MJ, Yancey PH, Fudge DS.

J Exp Biol. 2010 Apr;213(Pt 7):1092-9. doi: 10.1242/jeb.038992.


Osmoregulation of ceroid neuronal lipofuscinosis type 3 in the renal medulla.

Stein CS, Yancey PH, Martins I, Sigmund RD, Stokes JB, Davidson BL.

Am J Physiol Cell Physiol. 2010 Jun;298(6):C1388-400. doi: 10.1152/ajpcell.00272.2009. Epub 2010 Mar 10.


Macrophage LRP-1 controls plaque cellularity by regulating efferocytosis and Akt activation.

Yancey PG, Blakemore J, Ding L, Fan D, Overton CD, Zhang Y, Linton MF, Fazio S.

Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):787-95. doi: 10.1161/ATVBAHA.109.202051. Epub 2010 Feb 11.


Analysis of internal osmolality in developing coral larvae, Fungia scutaria.

Hagedorn M, Carter VL, Ly S, Andrell RM, Yancey PH, Leong JA, Kleinhans FW.

Physiol Biochem Zool. 2010 Jan-Feb;83(1):157-66. doi: 10.1086/648484.


Betaines and dimethylsulfoniopropionate as major osmolytes in cnidaria with endosymbiotic dinoflagellates.

Yancey PH, Heppenstall M, Ly S, Andrell RM, Gates RD, Carter VL, Hagedorn M.

Physiol Biochem Zool. 2010 Jan-Feb;83(1):167-73. doi: 10.1086/644625.


Renal dysfunction potentiates foam cell formation by repressing ABCA1.

Zuo Y, Yancey P, Castro I, Khan WN, Motojima M, Ichikawa I, Fogo AB, Linton MF, Fazio S, Kon V.

Arterioscler Thromb Vasc Biol. 2009 Sep;29(9):1277-82. doi: 10.1161/ATVBAHA.109.188995. Epub 2009 Aug 10. Erratum in: Arterioscler Thromb Vasc Biol. 2009 Dec 1;29(12):e133. Khan, Wasif [corrected to Khan, Wasif N].


Thiotaurine and hypotaurine contents in hydrothermal-vent polychaetes without thiotrophic endosymbionts: correlation With sulfide exposure.

Yancey PH, Ishikawa J, Meyer B, Girguis PR, Lee RW.

J Exp Zool A Ecol Genet Physiol. 2009 Jul 1;311(6):439-47. doi: 10.1002/jez.541.


Human C-reactive protein promotes oxidized low density lipoprotein uptake and matrix metalloproteinase-9 release in Wistar rats.

Singh U, Dasu MR, Yancey PG, Afify A, Devaraj S, Jialal I.

J Lipid Res. 2008 May;49(5):1015-23. doi: 10.1194/jlr.M700535-JLR200. Epub 2008 Feb 2.


Self-association of human PCSK9 correlates with its LDLR-degrading activity.

Fan D, Yancey PG, Qiu S, Ding L, Weeber EJ, Linton MF, Fazio S.

Biochemistry. 2008 Feb 12;47(6):1631-9. doi: 10.1021/bi7016359. Epub 2008 Jan 16.


Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.

Babaev VR, Ishiguro H, Ding L, Yancey PG, Dove DE, Kovacs WJ, Semenkovich CF, Fazio S, Linton MF.

Circulation. 2007 Sep 18;116(12):1404-12. Epub 2007 Aug 27.


Impaired secretion of apolipoprotein E2 from macrophages.

Fan D, Qiu S, Overton CD, Yancey PG, Swift LL, Jerome WG, Linton MF, Fazio S.

J Biol Chem. 2007 May 4;282(18):13746-53. Epub 2007 Mar 6.


A pathway-dependent on apoE, ApoAI, and ABCA1 determines formation of buoyant high-density lipoprotein by macrophage foam cells.

Yancey PG, Yu H, Linton MF, Fazio S.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):1123-31. Epub 2007 Feb 15.


Deletion of macrophage LDL receptor-related protein increases atherogenesis in the mouse.

Overton CD, Yancey PG, Major AS, Linton MF, Fazio S.

Circ Res. 2007 Mar 16;100(5):670-7. Epub 2007 Feb 15.


Severely altered cholesterol homeostasis in macrophages lacking apoE and SR-BI.

Yancey PG, Jerome WG, Yu H, Griffin EE, Cox BE, Babaev VR, Fazio S, Linton MF.

J Lipid Res. 2007 May;48(5):1140-9. Epub 2007 Feb 13.

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