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Effectiveness and safety of initiating adalimumab plus ≥12 mg/week methotrexate with adjustable dosing in biologic-naïve patients with early rheumatoid arthritis: HAWK study postmarketing surveillance in Japan.

Tanaka Y, Mimori T, Yamanaka H, Nakajima R, Morita K, Kimura J, Takeuchi T.

Mod Rheumatol. 2018 Jul 14:1-24. doi: 10.1080/14397595.2018.1500979. [Epub ahead of print]


Tissue-engineered submillimeter-diameter vascular grafts for free flap survival in rat model.

Yamanaka H, Yamaoka T, Mahara A, Morimoto N, Suzuki S.

Biomaterials. 2018 Jun 15;179:156-163. doi: 10.1016/j.biomaterials.2018.06.022. [Epub ahead of print]


Changes in nasotracheal tube depth in response to head and neck movement in children.

Yamanaka H, Tsukamoto M, Hitosugi T, Yokoyama T.

Acta Anaesthesiol Scand. 2018 Jul 3. doi: 10.1111/aas.13207. [Epub ahead of print]


Bisphenol A induces Nrf2-dependent drug-metabolizing enzymes through nitrosylation of Keap1.

Nakamura M, Yamanaka H, Oguro A, Imaoka S.

Drug Metab Pharmacokinet. 2018 Apr 22. pii: S1347-4367(17)30221-5. doi: 10.1016/j.dmpk.2018.04.003. [Epub ahead of print]


Escherichia coli chromosome-based T7-dependent constitutive overexpression system and its application to generating a phenylalanine producing strain.

Koma D, Kishida T, Yamanaka H, Moriyoshi K, Nagamori E, Ohmoto T.

J Biosci Bioeng. 2018 Jun 26. pii: S1389-1723(18)30015-X. doi: 10.1016/j.jbiosc.2018.05.014. [Epub ahead of print]


Real-time multiplex PCR for simultaneous detection of multiple species from environmental DNA: an application on two Japanese medaka species.

Tsuji S, Iguchi Y, Shibata N, Teramura I, Kitagawa T, Yamanaka H.

Sci Rep. 2018 Jun 14;8(1):9138. doi: 10.1038/s41598-018-27434-w.


Influence of Skeletal Muscle Mass and Spinal Alignment on Surgical Outcomes for Lumbar Spinal Stenosis.

Eguchi Y, Suzuki M, Yamanaka H, Tamai H, Kobayashi T, Orita S, Yamauchi K, Suzuki M, Inage K, Fujimoto K, Kanamoto H, Abe K, Norimoto M, Umimura T, Aoki Y, Koda M, Furuya T, Toyone T, Ozawa T, Takahashi K, Ohtori S.

Asian Spine J. 2018 Jun;12(3):556-562. doi: 10.4184/asj.2018.12.3.556. Epub 2018 Jun 4.


Identifying improvable employment-related factors in schizophrenia patients.

Hasegawa T, Hashimoto T, Kanahara N, Yamanaka H, Ishige M, Sato Y, Iyo M.

Psychiatry Res. 2018 Aug;266:199-205. doi: 10.1016/j.psychres.2018.05.064. Epub 2018 May 28.


Tocilizumab discontinuation after attaining remission in patients with rheumatoid arthritis who were treated with tocilizumab alone or in combination with methotrexate: results from a prospective randomised controlled study (the second year of the SURPRISE study).

Kaneko Y, Kato M, Tanaka Y, Inoo M, Kobayashi-Haraoka H, Amano K, Miyata M, Murakawa Y, Yasuoka H, Hirata S, Tanaka E, Miyasaka N, Yamanaka H, Yamamoto K, Takeuchi T; SURPRISE study group.

Ann Rheum Dis. 2018 May 31. pii: annrheumdis-2018-213416. doi: 10.1136/annrheumdis-2018-213416. [Epub ahead of print]


Factors associated with decreasing serum 25(OH)D among Japanese patients with rheumatoid arthritis: Results from the IORRA cohort study.

Nakayama M, Furuya T, Inoue E, Tanaka E, Ikari K, Nakajima A, Taniguchi A, Yamanaka H.

Mod Rheumatol. 2018 Jul 11:1-6. doi: 10.1080/14397595.2018.1481727. [Epub ahead of print]


New approach to predict photoallergic potentials of chemicals based on murine local lymph node assay.

Maeda Y, Hirosaki H, Yamanaka H, Takeyoshi M.

J Appl Toxicol. 2018 May 23. doi: 10.1002/jat.3643. [Epub ahead of print]


Genetic differences between type 1 diabetes with and without other autoimmune diseases.

Shimura K, Miura J, Kawamoto M, Kawaguchi Y, Yamanaka H, Uchigata Y.

Diabetes Metab Res Rev. 2018 May 15:e3023. doi: 10.1002/dmrr.3023. [Epub ahead of print]


A monolayer microfluidic device supporting mouse spermatogenesis with improved visibility.

Yamanaka H, Komeya M, Nakamura H, Sanjo H, Sato T, Yao M, Kimura H, Fujii T, Ogawa T.

Biochem Biophys Res Commun. 2018 Jun 12;500(4):885-891. doi: 10.1016/j.bbrc.2018.04.180. Epub 2018 Apr 30.


Recombinant interleukin-4 alleviates mechanical allodynia via injury-induced interleukin-4 receptor alpha in spinal microglia in a rat model of neuropathic pain.

Okutani H, Yamanaka H, Kobayashi K, Okubo M, Noguchi K.

Glia. 2018 Apr 25. doi: 10.1002/glia.23340. [Epub ahead of print]


No increased risk of herpes zoster in TNF inhibitor and non-TNF inhibitor users with rheumatoid arthritis: epidemiological study using the Japanese health insurance database.

Sakai R, Kasai S, Hirano F, Harada S, Kihara M, Yokoyama W, Tsutsumino M, Nagasaka K, Koike R, Yamanaka H, Miyasaka N, Harigai M.

Int J Rheum Dis. 2018 Apr 17. doi: 10.1111/1756-185X.13300. [Epub ahead of print]


Association of Serum Soluble CD163 with Polymyositis and Dermatomyositis, Especially in Anti-MDA5 Antibody-positive Cases.

Kawasumi H, Katsumata Y, Nishino A, Hirahara S, Kawaguchi Y, Kuwana M, Yamanaka H.

J Rheumatol. 2018 Jul;45(7):947-955. doi: 10.3899/jrheum.170997. Epub 2018 Apr 15.


Regional overdistension during prone positioning in a patient with acute respiratory failure who was ventilated with a low tidal volume: a case report.

Kotani T, Hanaoka M, Hirahara S, Yamanaka H, Teschner E, Shono A.

J Intensive Care. 2018 Mar 14;6:18. doi: 10.1186/s40560-018-0290-z. eCollection 2018.


Effect of Adalimumab on Refractory Arthritis in Juvenile Idiopathic Inflammatory Myopathy with Anti-MDA5 Autoantibody.

Miyamae T, Hara T, Hanaya A, Tani Y, Kishi T, Yamanaka H.

Case Rep Rheumatol. 2018 Feb 6;2018:2164312. doi: 10.1155/2018/2164312. eCollection 2018.


Efficacy and safety of sirukumab in Japanese patients with active rheumatoid arthritis who were refractory or intolerant to anti-tumor necrosis factor therapy: Subgroup analysis of a randomized, double-blind, multicenter, phase 3 study (SIRROUND-T).

Tanaka Y, Takeuchi T, Harigai M, Yamanaka H, Nakano T, Akagi K, Ukyo Y, Hsu B.

Mod Rheumatol. 2018 Apr 13:1-8. doi: 10.1080/14397595.2018.1452345. [Epub ahead of print]


Sirukumab in rheumatoid arthritis refractory to sulfasalazine or methotrexate: a randomized phase 3 safety and efficacy study in Japanese patients.

Takeuchi T, Yamanaka H, Harigai M, Tamamura R, Kato Y, Ukyo Y, Nakano T, Hsu B, Tanaka Y.

Arthritis Res Ther. 2018 Mar 7;20(1):42. doi: 10.1186/s13075-018-1536-9.


Age-related differences in recovery from inhalational anesthesia: a retrospective study.

Tsukamoto M, Yamanaka H, Yokoyama T.

Aging Clin Exp Res. 2018 Mar 3. doi: 10.1007/s40520-018-0924-y. [Epub ahead of print]


Hypouricaemic effects of yoghurt containing Lactobacillus gasseri PA-3 in patients with hyperuricaemia and/or gout: A randomised, double-blind, placebo-controlled study.

Yamanaka H, Taniguchi A, Tsuboi H, Kano H, Asami Y.

Mod Rheumatol. 2018 Mar 9:1-5. doi: 10.1080/14397595.2018.1442183. [Epub ahead of print]


Ultrasensitive Determination of Malathion Using Acetylcholinesterase Immobilized on Chitosan-Functionalized Magnetic Iron Nanoparticles.

Rodrigues NFM, Neto SY, Luz RCS, Damos FS, Yamanaka H.

Biosensors (Basel). 2018 Feb 13;8(1). pii: E16. doi: 10.3390/bios8010016.


In vitro mouse spermatogenesis with an organ culture method in chemically defined medium.

Sanjo H, Komeya M, Sato T, Abe T, Katagiri K, Yamanaka H, Ino Y, Arakawa N, Hirano H, Yao T, Asayama Y, Matsuhisa A, Yao M, Ogawa T.

PLoS One. 2018 Feb 12;13(2):e0192884. doi: 10.1371/journal.pone.0192884. eCollection 2018.


HLA-DRB1 Analysis Identified a Genetically Unique Subset within Rheumatoid Arthritis and Distinct Genetic Background of Rheumatoid Factor Levels from Anticyclic Citrullinated Peptide Antibodies.

Hiwa R, Ikari K, Ohmura K, Nakabo S, Matsuo K, Saji H, Yurugi K, Miura Y, Maekawa T, Taniguchi A, Yamanaka H, Matsuda F, Mimori T, Terao C.

J Rheumatol. 2018 Apr;45(4):470-480. doi: 10.3899/jrheum.170363. Epub 2018 Feb 1.


Capillary abnormalities observed by nailfold video-capillaroscopy in Japanese patients with systemic sclerosis.

Ichimura Y, Kawaguchi Y, Takagi K, Tochimoto A, Higuchi T, Kataoka S, Katsumata Y, Yamanaka H.

Mod Rheumatol. 2018 Feb 8:1-3. doi: 10.1080/14397595.2018.1430547. [Epub ahead of print] No abstract available.


Upregulation of calcium channel alpha-2-delta-1 subunit in dorsal horn contributes to spinal cord injury-induced tactile allodynia.

Kusuyama K, Tachibana T, Yamanaka H, Okubo M, Yoshiya S, Noguchi K.

Spine J. 2018 Jun;18(6):1062-1069. doi: 10.1016/j.spinee.2018.01.010. Epub 2018 Jan 31.


Efficacy and safety of sirukumab in Japanese patients with moderate to severe rheumatoid arthritis inadequately controlled by disease modifying anti-rheumatic drugs: Subgroup analysis of a phase 3 study.

Takeuchi T, Tanaka Y, Yamanaka H, Harigai M, Nakano T, Akagi K, Ukyo Y, Hsu B.

Mod Rheumatol. 2018 Feb 7:1-9. doi: 10.1080/14397595.2018.1428929. [Epub ahead of print]


Phosphate-dependent luminal ATP metabolism regulates transcellular calcium transport in intestinal epithelial cells.

Uekawa A, Yamanaka H, Lieben L, Kimira Y, Uehara M, Yamamoto Y, Kato S, Ito K, Carmeliet G, Masuyama R.

FASEB J. 2018 Apr;32(4):1903-1915. doi: 10.1096/fj.201700631R. Epub 2018 Jan 5.


Clinical efficacy, radiographic, and safety results of golimumab monotherapy in Japanese patients with active rheumatoid arthritis despite prior therapy with disease-modifying antirheumatic drugs: Final results of the GO-MONO trial through week 120.

Takeuchi T, Harigai M, Tanaka Y, Yamanaka H, Ishiguro N, Yamamoto K, Miyasaka N, Koike T, Ukyo Y, Ishii Y, Yoshinari T, Baker D; GO-MONO study group.

Mod Rheumatol. 2017 Dec 8:1-10. doi: 10.1080/14397595.2017.1404731. [Epub ahead of print]


Pumpless microfluidic system driven by hydrostatic pressure induces and maintains mouse spermatogenesis in vitro.

Komeya M, Hayashi K, Nakamura H, Yamanaka H, Sanjo H, Kojima K, Sato T, Yao M, Kimura H, Fujii T, Ogawa T.

Sci Rep. 2017 Nov 13;7(1):15459. doi: 10.1038/s41598-017-15799-3.


Stepwise dose increase of febuxostat is comparable with colchicine prophylaxis for the prevention of gout flares during the initial phase of urate-lowering therapy: results from FORTUNE-1, a prospective, multicentre randomised study.

Yamanaka H, Tamaki S, Ide Y, Kim H, Inoue K, Sugimoto M, Hidaka Y, Taniguchi A, Fujimori S, Yamamoto T.

Ann Rheum Dis. 2018 Feb;77(2):270-276. doi: 10.1136/annrheumdis-2017-211574. Epub 2017 Nov 4.


Applicability of an Integrated Testing Strategy consisting of in silico, in chemico and in vitro assays for evaluating the skin sensitization potencies of isocyanates.

Ohtake T, Maeda Y, Hayashi T, Yamanaka H, Nakai M, Takeyoshi M.

Toxicology. 2018 Jan 15;393:9-14. doi: 10.1016/j.tox.2017.10.015. Epub 2017 Nov 1.


Usefulness and limitations of sample pooling for environmental DNA metabarcoding of freshwater fish communities.

Sato H, Sogo Y, Doi H, Yamanaka H.

Sci Rep. 2017 Nov 1;7(1):14860. doi: 10.1038/s41598-017-14978-6.


Anesthetic considerations for a pediatric patient with Wolf-Hirschhorn syndrome: a case report.

Tsukamoto M, Yamanaka H, Yokoyama T.

J Dent Anesth Pain Med. 2017 Sep;17(3):231-233. doi: 10.17245/jdapm.2017.17.3.231. Epub 2017 Sep 25.


Infection rates in patients from five rheumatoid arthritis (RA) registries: contextualising an RA clinical trial programme.

Yamanaka H, Askling J, Berglind N, Franzen S, Frisell T, Garwood C, Greenberg JD, Ho M, Holmqvist M, Novelli Horne L, Inoue E, Michaud K, Pappas DA, Reed G, Symmons D, Tanaka E, Tran TN, Verstappen SMM, Wesby-van Swaay E, Nyberg F.

RMD Open. 2017 Oct 10;3(2):e000498. doi: 10.1136/rmdopen-2017-000498. eCollection 2017.


Distinct seasonal migration patterns of Japanese native and non-native genotypes of common carp estimated by environmental DNA.

Uchii K, Doi H, Yamanaka H, Minamoto T.

Ecol Evol. 2017 Sep 12;7(20):8515-8522. doi: 10.1002/ece3.3346. eCollection 2017 Oct.


Emergency endovascular treatment of a ruptured external carotid artery pseudoaneurysm caused by a cervical stab wound: A case report and literature review.

Tsurukiri J, Okumura E, Yamanaka H, Jimbo H, Hoshiai A.

Ulus Travma Acil Cerrahi Derg. 2017 Sep;23(5):433-437. doi: 10.5505/tjtes.2017.55560.


Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population.

Terao C, Okada Y, Ikari K, Kochi Y, Suzuki A, Ohmura K, Matsuo K, Taniguchi A, Kubo M, Raychaudhuri S, Yamamoto K, Yamanaka H, Kamatani Y, Mimori T, Matsuda F.

J Med Genet. 2017 Dec;54(12):853-858. doi: 10.1136/jmedgenet-2017-104779. Epub 2017 Oct 12.


Negative Regulation of TRPA1 by AMPK in Primary Sensory Neurons as a Potential Mechanism of Painful Diabetic Neuropathy.

Wang S, Kobayashi K, Kogure Y, Yamanaka H, Yamamoto S, Yagi H, Noguchi K, Dai Y.

Diabetes. 2018 Jan;67(1):98-109. doi: 10.2337/db17-0503. Epub 2017 Oct 12.


Involvement of the Arg566 residue of Aeromonas sobria serine protease in substrate specificity.

Kobayashi H, Otsubo T, Teraoka F, Ikeda K, Seike S, Takahashi E, Okamoto K, Yoshida T, Tsuge H, Yamanaka H.

PLoS One. 2017 Oct 12;12(10):e0186392. doi: 10.1371/journal.pone.0186392. eCollection 2017.


Incidence of comprehensive hospitalization due to infection, cardiovascular disease, fractures, and malignancies in patients with rheumatoid arthritis.

Sugimoto N, Nakajima A, Inoue E, Shidara K, Yamashita H, Mimori A, Tokuda H, Seto Y, Tanaka E, Momohara S, Taniguchi A, Yamanaka H.

Rheumatol Int. 2017 Nov;37(11):1871-1878. doi: 10.1007/s00296-017-3811-5. Epub 2017 Sep 7.


Reduction of methotrexate and glucocorticoids use after the introduction of biological disease-modifying anti-rheumatic drugs in patients with rheumatoid arthritis in daily practice based on the IORRA cohort.

Shimizu Y, Tanaka E, Inoue E, Shidara K, Sugimoto N, Seto Y, Nakajima A, Momohara S, Taniguchi A, Yamanaka H.

Mod Rheumatol. 2018 May;28(3):461-467. doi: 10.1080/14397595.2017.1369926. Epub 2017 Sep 14.


RANKL: A therapeutic target for bone destruction in rheumatoid arthritis.

Tanaka S, Tanaka Y, Ishiguro N, Yamanaka H, Takeuchi T.

Mod Rheumatol. 2018 Jan;28(1):9-16. doi: 10.1080/14397595.2017.1369491. Epub 2017 Sep 18. Review.


Onset ages of hepatopulmonary syndrome and pulmonary hypertension in patients with biliary atresia.

Ueno T, Saka R, Takama Y, Yamanaka H, Tazuke Y, Bessho K, Okuyama H.

Pediatr Surg Int. 2017 Oct;33(10):1053-1057. doi: 10.1007/s00383-017-4136-x. Epub 2017 Sep 4.


IL-23 and Th17 Disease in Inflammatory Arthritis.

Yago T, Nanke Y, Kawamoto M, Kobashigawa T, Yamanaka H, Kotake S.

J Clin Med. 2017 Aug 29;6(9). pii: E81. doi: 10.3390/jcm6090081. Review.


Productivity loss of Japanese patients with rheumatoid arthritis - A cross-sectional survey.

Sruamsiri R, Mahlich J, Tanaka E, Yamanaka H.

Mod Rheumatol. 2018 May;28(3):482-489. doi: 10.1080/14397595.2017.1361893. Epub 2017 Aug 29.


Reliability of the SF-36 in Japanese patients with systemic lupus erythematosus and its associations with disease activity and damage: a two-consecutive year prospective study.

Baba S, Katsumata Y, Okamoto Y, Kawaguchi Y, Hanaoka M, Kawasumi H, Yamanaka H.

Lupus. 2018 Mar;27(3):407-416. doi: 10.1177/0961203317725586. Epub 2017 Aug 10.


Anti-centromere antibody exhibits specific distribution levels among anti-nuclear antibodies and may characterize a distinct subset in rheumatoid arthritis.

Kuramoto N, Ohmura K, Ikari K, Yano K, Furu M, Yamakawa N, Hashimoto M, Ito H, Fujii T, Murakami K, Nakashima R, Imura Y, Yukawa N, Yoshifuji H, Taniguchi A, Momohara S, Yamanaka H, Matsuda F, Mimori T, Terao C.

Sci Rep. 2017 Jul 31;7(1):6911. doi: 10.1038/s41598-017-07137-4.

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