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Intra-embryo Gene Cassette Knockin by CRISPR/Cas9-Mediated Genome Editing with Adeno-Associated Viral Vector.

Mizuno N, Mizutani E, Sato H, Kasai M, Ogawa A, Suchy F, Yamaguchi T, Nakauchi H.

iScience. 2018 Nov 2;9:286-297. doi: 10.1016/j.isci.2018.10.030. [Epub ahead of print]


Discovery of a novel azetidine scaffold for colony stimulating factor-1 receptor (CSF-1R) Type II inhibitors by the use of docking models.

Ikegashira K, Ikenogami T, Yamasaki T, Hase Y, Yamaguchi T, Inagaki K, Doi S, Adachi T, Koga Y, Hashimoto H.

Bioorg Med Chem Lett. 2018 Nov 1. pii: S0960-894X(18)30852-7. doi: 10.1016/j.bmcl.2018.10.051. [Epub ahead of print]


Specialty-Related Differences in the Acute-Phase Treatment and Prognosis in Patients With Acute Heart Failure - Insights From REALITY-AHF.

Kondo T, Okumura T, Matsue Y, Shiraishi A, Kagiyama N, Yamaguchi T, Kuroda S, Kida K, Mizuno A, Oishi S, Inuzuka Y, Akiyama E, Matsukawa R, Kato K, Suzuki S, Naruke T, Yoshioka K, Miyoshi T, Baba Y, Yamamoto M, Murai K, Mizutani K, Yoshida K, Kitai T, Murohara T.

Circ J. 2018 Nov 15. doi: 10.1253/circj.CJ-18-0724. [Epub ahead of print]


Pre-existing pulmonary fibrosis is a risk factor for anti-PD-1-related pneumonitis in patients with non-small cell lung cancer: A retrospective analysis.

Yamaguchi T, Shimizu J, Hasegawa T, Horio Y, Inaba Y, Yatabe Y, Hida T.

Lung Cancer. 2018 Nov;125:212-217. doi: 10.1016/j.lungcan.2018.10.001. Epub 2018 Oct 3.


Simultaneous occurrence of hypermucoviscous Klebsiella pneumoniae emphysematous prostatic abscess, emphysematous cystitis, and renal abscess.

Suzuki K, Yamaguchi T, Yanai M.

IDCases. 2018 Nov 3;14:e00464. doi: 10.1016/j.idcr.2018.e00464. eCollection 2018.


Genetic diversity and distribution dynamics of multidrug-resistant Mycobacterium tuberculosis isolates in Nepal.

Maharjan B, Nakajima C, Isoda N, Thapa J, Poudel A, Shah Y, Yamaguchi T, Shrestha B, Hoffmann H, Avsar K, Shrestha A, Gordon SV, Suzuki Y.

Sci Rep. 2018 Nov 9;8(1):16634. doi: 10.1038/s41598-018-34306-w.


Smartphone problem-solving and behavioural activation therapy to reduce fear of recurrence among patients with breast cancer (SMartphone Intervention to LEssen fear of cancer recurrence: SMILE project): protocol for a randomised controlled trial.

Akechi T, Yamaguchi T, Uchida M, Imai F, Momino K, Katsuki F, Sakurai N, Miyaji T, Horikoshi M, Furukawa TA, Iwata H, Uchitomi Y.

BMJ Open. 2018 Nov 8;8(11):e024794. doi: 10.1136/bmjopen-2018-024794.


Genetic variants in CCL5 and CCR5 genes and serum VEGF-A levels predict efficacy of bevacizumab in metastatic colorectal cancer patients.

Suenaga M, Cao S, Zhang W, Yang D, Ning Y, Okazaki S, Berger MD, Miyamoto Y, Schirripa M, Soni S, Barzi A, Yamaguchi T, Lenz HJ.

Int J Cancer. 2018 Nov 9. doi: 10.1002/ijc.31968. [Epub ahead of print]


Simultaneous determination of sodium iron chlorophyllin and sodium copper chlorophyllin in food using high-performance liquid chromatography and ultra-performance liquid chromatography-mass spectrometry.

Chong HS, Sim S, Yamaguchi T, Park J, Lee C, Kim M, Lee G, Yun SS, Lim HS, Suh HJ.

Food Chem. 2019 Mar 15;276:390-396. doi: 10.1016/j.foodchem.2018.10.015. Epub 2018 Oct 4.


Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM.

Park MH, Lee JY, Park KH, Jung IK, Kim KT, Lee YS, Ryu HH, Jeong Y, Kang M, Schwaninger M, Gulbins E, Reichel M, Kornhuber J, Yamaguchi T, Kim HJ, Kim SH, Schuchman EH, Jin HK, Bae JS.

Neuron. 2018 Nov 7;100(3):762. doi: 10.1016/j.neuron.2018.10.038. No abstract available.


Fistula between the Thoracic Duct and an Unusual Vessel Aneurysm Branching Off the Abdominal Aorta Revealed by Aneurysm Rupture: A Case Report.

Yamaguchi T, Tanaka A, Aoyama H, Nakamura M, Tadakoshi M, Kametani R, Ohashi T.

Ann Vasc Dis. 2018 Sep 25;11(3):339-342. doi: 10.3400/


Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection.

Lee AY, Ewing AD, Ellrott K, Hu Y, Houlahan KE, Bare JC, Espiritu SMG, Huang V, Dang K, Chong Z, Caloian C, Yamaguchi TN; ICGC-TCGA DREAM Somatic Mutation Calling Challenge Participants, Kellen MR, Chen K, Norman TC, Friend SH, Guinney J, Stolovitzky G, Haussler D, Margolin AA, Stuart JM, Boutros PC.

Genome Biol. 2018 Nov 6;19(1):188. doi: 10.1186/s13059-018-1539-5.


A combination of routine laboratory findings and vital signs can predict survival of advanced cancer patients without physician evaluation: a fractional polynomial model.

Hamano J, Takeuchi A, Yamaguchi T, Baba M, Imai K, Ikenaga M, Matsumoto Y, Sekine R, Yamaguchi T, Hirohashi T, Tajima T, Tatara R, Watanabe H, Otani H, Nagaoka H, Mori M, Tei Y, Hiramoto S, Morita T.

Eur J Cancer. 2018 Nov 1;105:50-60. doi: 10.1016/j.ejca.2018.09.037. [Epub ahead of print]


Ancient features of the MHC class II presentation pathway, and a model for the possible origin of MHC molecules.

Dijkstra JM, Yamaguchi T.

Immunogenetics. 2018 Oct 30. doi: 10.1007/s00251-018-1090-2. [Epub ahead of print] Review.


Expression and Functional Characterization of Drug Transporters in Brain Microvascular Endothelial Cells Derived from Human Induced Pluripotent Stem Cells.

Kurosawa T, Tega Y, Higuchi K, Yamaguchi T, Nakakura T, Mochizuki T, Kusuhara H, Kawabata K, Deguchi Y.

Mol Pharm. 2018 Nov 12. doi: 10.1021/acs.molpharmaceut.8b00697. [Epub ahead of print]


Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure.

Nomura S, Satoh M, Fujita T, Higo T, Sumida T, Ko T, Yamaguchi T, Tobita T, Naito AT, Ito M, Fujita K, Harada M, Toko H, Kobayashi Y, Ito K, Takimoto E, Akazawa H, Morita H, Aburatani H, Komuro I.

Nat Commun. 2018 Oct 30;9(1):4435. doi: 10.1038/s41467-018-06639-7.


The Virtual Kitchen Challenge: preliminary data from a novel virtual reality test of mild difficulties in everyday functioning.

Giovannetti T, Yamaguchi T, Roll E, Harada T, Rycroft SS, Divers R, Hulswit J, Tan CC, Matchanova A, Ham L, Hackett K, Mis R.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2018 Oct 28:1-19. doi: 10.1080/13825585.2018.1536774. [Epub ahead of print]


The cleistogamy of the superwoman1-cleistogamy1 mutation is sensitive to low temperatures during the lodicule-forming stage.

Ohmori S, Koike S, Hayashi T, Yamaguchi T, Kuroki M, Yoshida H.

Breed Sci. 2018 Sep;68(4):432-441. doi: 10.1270/jsbbs.18028. Epub 2018 Aug 28.


Impact of Corneal Higher-Order Aberrations on Visual Acuity After Deep Anterior Lamellar Keratoplasty in Treating Keratoconus.

Suzuki N, Yamaguchi T, Tomida D, Tsubota K, Shimazaki J.

Eye Contact Lens. 2018 Oct 22. doi: 10.1097/ICL.0000000000000561. [Epub ahead of print]


Orthognathic surgery induces genomewide changes longitudinally in DNA methylation in saliva.

Yamaguchi T, Hosomichi K, Takahashi M, Haga S, Nakawaki T, Hikita Y, Maki K, Tajima A.

Oral Dis. 2018 Oct 26. doi: 10.1111/odi.12998. [Epub ahead of print]


HBV patients with low HBsAg and high HBcrAg titers have a high risk of HBV-related HCC.

Suzuki Y, Maekawa S, Komatsu N, Sato M, Tatsumi A, Miura M, Matsuda S, Muraoka M, Nakakuki N, Shindo H, Amemiya F, Takano S, Fukasawa M, Nakayama Y, Yamaguchi T, Inoue T, Sato T, Sakamoto M, Yamashita A, Moriishi K, Enomoto N.

Hepatol Res. 2018 Oct 22. doi: 10.1111/hepr.13277. [Epub ahead of print]


CYP81A P450s are involved in concomitant cross-resistance to ALS and ACCase herbicides in Echinochloa phyllopogon.

Iwakami S, Kamidate Y, Yamaguchi T, Ishizaka M, Endo M, Suda H, Nagai K, Sunohara Y, Toki S, Uchino A, Tominaga T, Matsumoto H.

New Phytol. 2018 Oct 22. doi: 10.1111/nph.15552. [Epub ahead of print]


Adsorption of colour from dye wastewater effluent of a down-flow hanging sponge reactor on purified coconut fibre.

Nguyet PN, Hata Y, Maharjan N, Watari T, Hatamoto M, Yamaguchi T.

Environ Technol. 2018 Nov 15:1-10. doi: 10.1080/09593330.2018.1534000. [Epub ahead of print]


Characterization of downflow hanging sponge reactors with regard to structure, process function, and microbial community compositions.

Hatamoto M, Okubo T, Kubota K, Yamaguchi T.

Appl Microbiol Biotechnol. 2018 Oct 20. doi: 10.1007/s00253-018-9406-6. [Epub ahead of print] Review.


Feasibility of early multimodal interventions for elderly patients with advanced pancreatic and non-small-cell lung cancer.

Naito T, Mitsunaga S, Miura S, Tatematsu N, Inano T, Mouri T, Tsuji T, Higashiguchi T, Inui A, Okayama T, Yamaguchi T, Morikawa A, Mori N, Takahashi T, Strasser F, Omae K, Mori K, Takayama K.

J Cachexia Sarcopenia Muscle. 2018 Oct 18. doi: 10.1002/jcsm.12351. [Epub ahead of print]


Hyperprogressive disease in patients with non-small cell lung cancer treated with nivolumab: A case series.

Kanazu M, Edahiro R, Krebe H, Nishida K, Ishijima M, Uenami T, Akazawa Y, Yano Y, Yamaguchi T, Mori M.

Thorac Cancer. 2018 Oct 17. doi: 10.1111/1759-7714.12894. [Epub ahead of print]


Japanese Antibacterial Drug Management for Cardiac Sarcoidosis (J-ACNES): A multicenter, open-label, randomized, controlled study.

Ishibashi K, Eishi Y, Tahara N, Asakura M, Sakamoto N, Nakamura K, Takaya Y, Nakamura T, Yazaki Y, Yamaguchi T, Asakura K, Anzai T, Noguchi T, Yasuda S, Terasaki F, Hamasaki T, Kusano K.

J Arrhythm. 2018 Aug 31;34(5):520-526. doi: 10.1002/joa3.12084. eCollection 2018 Oct.


Effect of the combination of motor imagery and electrical stimulation on upper extremity motor function in patients with chronic stroke: preliminary results.

Okuyama K, Ogura M, Kawakami M, Tsujimoto K, Okada K, Miwa K, Takahashi Y, Abe K, Tanabe S, Yamaguchi T, Liu M.

Ther Adv Neurol Disord. 2018 Oct 9;11:1756286418804785. doi: 10.1177/1756286418804785. eCollection 2018.


An interspecies barrier to tetraploid complementation and chimera formation.

Yamaguchi T, Sato H, Kobayashi T, Kato-Itoh M, Goto T, Hara H, Mizuno N, Yanagida A, Umino A, Hamanaka S, Suchy F, Masaki H, Ota Y, Hirabayashi M, Nakauchi H.

Sci Rep. 2018 Oct 16;8(1):15289. doi: 10.1038/s41598-018-33690-7.


Excessive hair growth in a patient with psoriatic erythroderma following secukinumab administration.

Mashima E, Sawada Y, Yamaguchi T, Yoshioka H, Ohmori S, Haruyama S, Okada E, Nakamura M.

Eur J Dermatol. 2018 Aug 1;28(4):539-540. doi: 10.1684/ejd.2018.3327. No abstract available.


Heating sensation in patients with and without spinal fixation devices during MRI examination at different magnetic field strengths.

Yamaguchi T, Abe Y, Ichino Y, Satoh S, Masuda T, Kimura S, Ito M, Yamamoto T.

J Magn Reson Imaging. 2018 Oct 14. doi: 10.1002/jmri.26307. [Epub ahead of print]


Nitric Oxide Production from Nitrite Reduction and Hydroxylamine Oxidation by Copper-containing Dissimilatory Nitrite Reductase (NirK) from the Aerobic Ammonia-oxidizing Archaeon, Nitrososphaera viennensis.

Kobayashi S, Hira D, Yoshida K, Toyofuku M, Shida Y, Ogasawara W, Yamaguchi T, Araki N, Oshiki M.

Microbes Environ. 2018 Oct 12. doi: 10.1264/jsme2.ME18058. [Epub ahead of print]


Cytokine levels in the aqueous humor are associated with corneal thickness in eyes with bullous keratopathy.

Suzuki N, Yamaguchi T, Shibata S, Nagai T, Noma H, Tsubota K, Shimazaki J.

Am J Ophthalmol. 2018 Oct 11. pii: S0002-9394(18)30590-7. doi: 10.1016/j.ajo.2018.10.008. [Epub ahead of print]


Estimating the annual risk of tuberculosis infection in Japan from interferon-gamma release assay data.

Hamaguchi Y, Yamaguchi T, Nishiura H.

J Theor Biol. 2019 Jan 7;460:125-133. doi: 10.1016/j.jtbi.2018.10.017. Epub 2018 Oct 10.


Assessment of bleeding in patients with disseminated intravascular coagulation after receiving surgery and recombinant human soluble thrombomodulin: A cohort study using a database.

Yamaguchi T, Kitajima Y, Miyauchi Y, Izawa K, Tanaka M, Hirata M, Sadatsuki Y, Ogawa Y.

PLoS One. 2018 Oct 8;13(10):e0205146. doi: 10.1371/journal.pone.0205146. eCollection 2018.


A Novel Antigen-Sampling Cell in the Teleost Gill Epithelium With the Potential for Direct Antigen Presentation in Mucosal Tissue.

Kato G, Miyazawa H, Nakayama Y, Ikari Y, Kondo H, Yamaguchi T, Sano M, Fischer U.

Front Immunol. 2018 Sep 20;9:2116. doi: 10.3389/fimmu.2018.02116. eCollection 2018.


INSM1 expression in pancreatic neuroendocrine tumors in endoscopic ultrasound-guided fine needle aspiration cytology: an analysis of 14 patients.

Takase Y, Naito Y, Okabe Y, Ishida Y, Yamaguchi T, Abe H, Murata K, Ito T, Tanigawa M, Kawahara A, Yano H, Akiba J.

Cytopathology. 2018 Oct 5. doi: 10.1111/cyt.12640. [Epub ahead of print]


Relationship between the Functional Independence Measure and Mann Assessment of Swallowing Ability in hospitalized patients with pneumonia.

Mitani Y, Oki Y, Fujimoto Y, Yamaguchi T, Yamada Y, Yamada K, Ito T, Shiotani H, Ishikawa A.

Geriatr Gerontol Int. 2018 Oct 5. doi: 10.1111/ggi.13543. [Epub ahead of print]


Multidisciplinary therapy for scirrhous gastric cancer: a retrospective analysis and proposal of new treatment strategy.

Fushida S, Kinoshita J, Oyama K, Fujimura T, Tsukada T, Yamaguchi T, Ninomiya I, Ohta T.

Cancer Manag Res. 2018 Sep 24;10:3833-3839. doi: 10.2147/CMAR.S174950. eCollection 2018.


Employment status was highly associated with quality of life after allogeneic hematopoietic cell transplantation, and the association may differ according to patient age and graft-versus-host disease status: analysis of a nationwide QOL survey.

Kurosawa S, Yamaguchi T, Oshima K, Yanagisawa A, Fukuda T, Kanamori H, Mori T, Takahashi S, Kondo T, Fujisawa S, Onishi Y, Yano S, Onizuka M, Kanda Y, Mizuno I, Taniguchi S, Yamashita T, Inamoto Y, Okamoto S, Atsuta Y.

Bone Marrow Transplant. 2018 Oct 4. doi: 10.1038/s41409-018-0343-x. [Epub ahead of print] No abstract available.


Hemorrhagic shock due to branch injury of the left internal thoracic artery two days after pericardiocentesis.

Hijikata S, Miyamoto T, Yamaguchi T, Yamaguchi J, Iwai T, Watanabe K, Sagawa Y, Masuda R, Miyazaki R, Miwa N, Hara N, Nagata Y, Nozato T.

J Cardiol Cases. 2018 Mar 30;18(1):5-8. doi: 10.1016/j.jccase.2018.02.009. eCollection 2018 Jul.


Incorrect Holter-ECG analysis caused by the pacemaker delivering small high-frequency currents for thoracic impedance measurement.

Chinushi M, Tachikawa H, Chinushi Y, Yamaguchi T, Saitoh O, Tsuda T.

J Cardiol Cases. 2017 Sep 12;16(6):219-222. doi: 10.1016/j.jccase.2017.08.007. eCollection 2017 Dec.


Thermal behavior, structure, dynamic properties of aqueous glycine solutions confined in mesoporous silica MCM-41 investigated by x-ray diffraction and quasi-elastic neutron scattering.

Yoshida K, Inoue T, Torigoe M, Yamada T, Shibata K, Yamaguchi T.

J Chem Phys. 2018 Sep 28;149(12):124502. doi: 10.1063/1.5039892.


Case: Authentic multimodal therapy and liver resection for an initially unresectable intrahepatic cholangiocarcinoma.

Sakata K, Kijima D, Yamaguchi T, Furuhashi T, Abe T, Iwamoto H, Morita K.

Int J Surg Case Rep. 2018;51:409-414. doi: 10.1016/j.ijscr.2018.08.059. Epub 2018 Sep 15.


Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM.

Park MH, Lee JY, Park KH, Jung IK, Kim KT, Lee YS, Ryu HH, Jeong Y, Kang M, Schwaninger M, Gulbins E, Reichel M, Kornhuber J, Yamaguchi T, Kim HJ, Kim SH, Schuchman EH, Jin HK, Bae JS.

Neuron. 2018 Oct 10;100(1):167-182.e9. doi: 10.1016/j.neuron.2018.09.010. Epub 2018 Sep 27. Erratum in: Neuron. 2018 Nov 7;100(3):762.


Tranexamic Acid Ameliorates Nonmelanoma Skin Cancer Induced by Long-term Ultraviolet A Irradiation.

Hiramoto K, Yamate Y, Sugiyama D, Matsuda K, Iizuka Y, Yamaguchi T.

Photochem Photobiol. 2018 Sep 29. doi: 10.1111/php.13025. [Epub ahead of print]


Simultaneous laparoscopic left hemicolectomy and spleen-preserving distal pancreatectomy for descending colon cancer with pancreatic invasion.

Nagasaki T, Mise Y, Honma S, Sato T, Akiyoshi T, Fukunaga Y, Tominaga T, Nagaoka T, Yamaguchi T, Ueno M.

Asian J Endosc Surg. 2018 Sep 27. doi: 10.1111/ases.12655. [Epub ahead of print]


Elevation of preoperative recipient aqueous cytokine levels in eyes with primary graft failure after corneal transplantation.

Yamaguchi T, Higa K, Tsubota K, Shimazaki J.

Mol Vis. 2018 Sep 13;24:613-620. eCollection 2018.


Evaluation of trophic transfer in the microbial food web during sludge degradation based on 13C and 15N natural abundance.

Onodera T, Kanaya G, Hatamoto M, Kohzu A, Iguchi A, Takimoto Y, Yamaguchi T, Mizuochi M, Syutsubo K.

Water Res. 2018 Dec 1;146:30-36. doi: 10.1016/j.watres.2018.09.016. Epub 2018 Sep 5.


Efficacy of immediate-release oxycodone for dyspnoea in cancer patient: cancer dyspnoea relief (CDR) trial.

Yamaguchi T, Matsuda Y, Matsuoka H, Hisanaga T, Osaka I, Watanabe H, Maeda I, Imai K, Tsuneto S, Wagatsuma Y, Kizawa Y.

Jpn J Clin Oncol. 2018 Sep 27. doi: 10.1093/jjco/hyy139. [Epub ahead of print]


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