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Items: 30

1.

Helietta apiculata: a tropical weapon against Chagas disease.

Elena Ferreira M, Rojas de Arias A, Yaluff G, Vera de Bilbao N, Nakayama H, Torres S, Schinini A, Torres S, Serna E, Torrecilhas AC, Fournet A, Cebrián-Torrejón G.

Nat Prod Res. 2018 May 10:1-4. doi: 10.1080/14786419.2018.1472594. [Epub ahead of print]

PMID:
29745731
2.

Looking for combination of benznidazole and Trypanosoma cruzi-triosephosphate isomerase inhibitors for Chagas disease treatment.

Aguilera E, Varela J, Serna E, Torres S, Yaluff G, Bilbao NV, Cerecetto H, Alvarez G, González M.

Mem Inst Oswaldo Cruz. 2018 Mar;113(3):153-160. doi: 10.1590/0074-02760170267.

3.

In vitro antiprotozoal activity of (S)-cis-Verbenol against Leishmania spp. and Trypanosoma cruzi.

Yaluff G, Vega C, Alvarenga N.

Acta Trop. 2017 Apr;168:41-44. doi: 10.1016/j.actatropica.2016.12.013. Epub 2017 Jan 3.

PMID:
28062234
4.

New approach towards the synthesis of selenosemicarbazones, useful compounds for Chagas' disease.

Pizzo C, Faral-Tello P, Yaluff G, Serna E, Torres S, Vera N, Saiz C, Robello C, Mahler G.

Eur J Med Chem. 2016 Feb 15;109:107-13. doi: 10.1016/j.ejmech.2015.12.040. Epub 2015 Dec 23.

PMID:
26774036
5.

Potent and Selective Inhibitors of Trypanosoma cruzi Triosephosphate Isomerase with Concomitant Inhibition of Cruzipain: Inhibition of Parasite Growth through Multitarget Activity.

Aguilera E, Varela J, Birriel E, Serna E, Torres S, Yaluff G, de Bilbao NV, Aguirre-López B, Cabrera N, Díaz Mazariegos S, de Gómez-Puyou MT, Gómez-Puyou A, Pérez-Montfort R, Minini L, Merlino A, Cerecetto H, González M, Alvarez G.

ChemMedChem. 2016 Jun 20;11(12):1328-38. doi: 10.1002/cmdc.201500385. Epub 2015 Oct 23.

PMID:
26492824
6.

Development of bis-thiazoles as inhibitors of triosephosphate isomerase from Trypanosoma cruzi. Identification of new non-mutagenic agents that are active in vivo.

Álvarez G, Martínez J, Varela J, Birriel E, Cruces E, Gabay M, Leal SM, Escobar P, Aguirre-López B, Cabrera N, Tuena de Gómez-Puyou M, Gómez Puyou A, Pérez-Montfort R, Yaluff G, Torres S, Serna E, Vera de Bilbao N, González M, Cerecetto H.

Eur J Med Chem. 2015 Jul 15;100:246-56. doi: 10.1016/j.ejmech.2015.06.018. Epub 2015 Jun 12.

PMID:
26094151
7.

Identification of a new amide-containing thiazole as a drug candidate for treatment of Chagas' disease.

Álvarez G, Varela J, Cruces E, Fernández M, Gabay M, Leal SM, Escobar P, Sanabria L, Serna E, Torres S, Figueredo Thiel SJ, Yaluff G, Vera de Bilbao NI, Cerecetto H, González M.

Antimicrob Agents Chemother. 2015 Mar;59(3):1398-404. doi: 10.1128/AAC.03814-14. Epub 2014 Dec 15.

8.

In vivo anti-Trypanosoma cruzi activity of hydro-ethanolic extract and isolated active principles from Aristeguietia glutinosa and mechanism of action studies.

Varela J, Serna E, Torres S, Yaluff G, de Bilbao NI, Miño P, Chiriboga X, Cerecetto H, González M.

Molecules. 2014 Jun 23;19(6):8488-502. doi: 10.3390/molecules19068488.

9.

Optimization of antitrypanosomatid agents: identification of nonmutagenic drug candidates with in vivo activity.

Álvarez G, Varela J, Márquez P, Gabay M, Arias Rivas CE, Cuchilla K, Echeverría GA, Piro OE, Chorilli M, Leal SM, Escobar P, Serna E, Torres S, Yaluff G, Vera de Bilbao NI, González M, Cerecetto H.

J Med Chem. 2014 May 22;57(10):3984-99. doi: 10.1021/jm500018m. Epub 2014 May 2.

PMID:
24749923
10.

3-Trifluoromethylquinoxaline N,N'-dioxides as anti-trypanosomatid agents. Identification of optimal anti-T. cruzi agents and mechanism of action studies.

Benitez D, Cabrera M, Hernández P, Boiani L, Lavaggi ML, Di Maio R, Yaluff G, Serna E, Torres S, Ferreira ME, Vera de Bilbao N, Torres E, Pérez-Silanes S, Solano B, Moreno E, Aldana I, López de Ceráin A, Cerecetto H, González M, Monge A.

J Med Chem. 2011 May 26;54(10):3624-36. doi: 10.1021/jm2002469. Epub 2011 May 4.

PMID:
21506600
11.

Antileishmanial activity of furoquinolines and coumarins from Helietta apiculata.

Ferreira ME, de Arias AR, Yaluff G, de Bilbao NV, Nakayama H, Torres S, Schinini A, Guy I, Heinzen H, Fournet A.

Phytomedicine. 2010 Apr;17(5):375-8. doi: 10.1016/j.phymed.2009.09.009. Epub 2009 Oct 29.

PMID:
19879121
12.

In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles.

Boiani L, Gerpe A, Arán VJ, Torres de Ortiz S, Serna E, Vera de Bilbao N, Sanabria L, Yaluff G, Nakayama H, Rojas de Arias A, Maya JD, Morello JA, Cerecetto H, González M.

Eur J Med Chem. 2009 Mar;44(3):1034-40. doi: 10.1016/j.ejmech.2008.06.024. Epub 2008 Jun 28.

PMID:
18706738
13.

Leishmanicidal activity of Maytenus illicifolia roots.

Alvarenga N, Canela N, Gómez R, Yaluff G, Maldonado M.

Fitoterapia. 2008 Jul;79(5):381-3. doi: 10.1016/j.fitote.2008.03.001. Epub 2008 Apr 18.

PMID:
18504075
14.

Activity of a hydroxybibenzyl bryophyte constituent against Leishmania spp. and Trypanosoma cruzi: in silico, in vitro and in vivo activity studies.

Roldos V, Nakayama H, Rolón M, Montero-Torres A, Trucco F, Torres S, Vega C, Marrero-Ponce Y, Heguaburu V, Yaluff G, Gómez-Barrio A, Sanabria L, Ferreira ME, Rojas de Arias A, Pandolfi E.

Eur J Med Chem. 2008 Sep;43(9):1797-807. doi: 10.1016/j.ejmech.2007.11.007. Epub 2007 Nov 19.

PMID:
18192088
15.

2H-benzimidazole 1,3-dioxide derivatives: a new family of water-soluble anti-trypanosomatid agents.

Boiani M, Boiani L, Denicola A, Torres de Ortiz S, Serna E, Vera de Bilbao N, Sanabria L, Yaluff G, Nakayama H, Rojas de Arias A, Vega C, Rolan M, Gómez-Barrio A, Cerecetto H, Gonzalez M.

J Med Chem. 2006 Jun 1;49(11):3215-24.

PMID:
16722639
16.

Indazole N-oxide derivatives as antiprotozoal agents: synthesis, biological evaluation and mechanism of action studies.

Gerpe A, Aguirre G, Boiani L, Cerecetto H, González M, Olea-Azar C, Rigol C, Maya JD, Morello A, Piro OE, Arán VJ, Azqueta A, de Ceráin AL, Monge A, Rojas MA, Yaluff G.

Bioorg Med Chem. 2006 May 15;14(10):3467-80. Epub 2006 Feb 17.

PMID:
16483783
17.

Screening of New Caledonian and Vanuatu medicinal plants for antiprotozoal activity.

Billo M, Fournet A, Cabalion P, Waikedre J, Bories C, Loiseau P, Prina E, de Arias AR, Yaluff G, Fourneau C, Hocquemiller R.

J Ethnopharmacol. 2005 Jan 15;96(3):569-75. Epub 2004 Dec 1.

PMID:
15619580
18.

Bioactive alkyl phenols and embelin from Oxalis erythrorhiza.

Feresin GE, Tapia A, Sortino M, Zacchino S, de Arias AR, Inchausti A, Yaluff G, Rodriguez J, Theoduloz C, Schmeda-Hirschmann G.

J Ethnopharmacol. 2003 Oct;88(2-3):241-7.

PMID:
12963150
19.

Leishmanicidal activity of some aliphatic diamines and amino-alcohols.

del Olmo E, Alves M, López JL, Inchaustti A, Yaluff G, Rojas de Arias A, San Feliciano A.

Bioorg Med Chem Lett. 2002 Feb 25;12(4):659-62.

PMID:
11844694
20.

Cryptofolione derivatives from Cryptocarya alba fruits.

Schmeda-Hirschmann G, Astudillo L, Bastida J, Codina C, Rojas De Arias A, Ferreira ME, Inchaustti A, Yaluff G.

J Pharm Pharmacol. 2001 Apr;53(4):563-7.

PMID:
11341375
21.

Synthesis and in vitro antiprotozoal activity of thiophene ring-containing quinones.

Valderrama J, Fournet A, Valderrama C, Bastias S, Astudillo C, Rojas de Arias A, Inchausti A, Yaluff G.

Chem Pharm Bull (Tokyo). 1999 Sep;47(9):1221-6.

PMID:
10517004
22.

Leishmanicidal activity of combretastatin analogues and heteroanalogues.

del Rey B, Ramos AC, Caballero E, Inchaustti A, Yaluff G, Medarde M, Rojas de Arias A, San Feliciano A.

Bioorg Med Chem Lett. 1999 Sep 20;9(18):2711-4.

PMID:
10509921
23.

Acetogenins and other compounds from Rollinia emarginata and their antiprotozoal activities.

Février A, Ferreira ME, Fournet A, Yaluff G, Inchausti A, Rojas de Arias A, Hocquemiller R, Waechter AI.

Planta Med. 1999 Feb;65(1):47-9.

PMID:
10083845
24.

Trypanocidal bisbenzylisoquinoline alkaloids are inhibitors of trypanothione reductase.

Fournet A, Inchausti A, Yaluff G, Rojas De Arias A, Guinaudeau H, Bruneton J, Breidenbach MA, Karplus PA, Faerman CH.

J Enzyme Inhib. 1998 Feb;13(1):1-9.

PMID:
9879510
25.

Seroprevalence and sociocultural conditionants of Chagas disease in school-aged children of marginal zones of Asunción.

Vera NI, Maldonado M, Yaluff G, Simancas L, de Arias AR.

Rev Soc Bras Med Trop. 1998 Jul-Aug;31(4):347-53.

PMID:
9662961
26.

Activity of compounds isolated from Chilean lichens against experimental cutaneous leishmaniasis.

Fournet A, Ferreira ME, Rojas de Arias A, Torres de Ortiz S, Inchausti A, Yaluff G, Quilhot W, Fernandez E, Hidalgo ME.

Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1997 Jan;116(1):51-4.

PMID:
9080673
27.

In vitro and in vivo leishmanicidal studies of Peperomia galioides (Piperaceae).

Fournet A, Ferreira ME, Rojas de Arias A, Fuentes S, Torres S, Inchausti A, Yaluff G, Nakayama H, Mahiou V, Hocquemiller R, Cavé A.

Phytomedicine. 1996 Nov;3(3):271-5. doi: 10.1016/S0944-7113(96)80065-1.

PMID:
23195082
28.

New prenylated quinones from Peperomia galioides.

Mahiou V, Roblot F, Hocquemiller R, Cavé A, Rojas De Arias A, Inchausti A, Yaluff G, Fournet A.

J Nat Prod. 1996 Jul;59(7):694-7.

PMID:
8759169
29.

Characterization of Paraguayan Trypanosoma cruzi strains isolated from acute patients of Chagas disease.

Acosta N, Maldonado M, Sanabria L, Yaluff G, Fuentes S, Torres S, Ferreira ME, Rojas de Arias A, Shozawa T.

Trop Med Parasitol. 1995 Sep;46(3):195-200.

PMID:
8533024
30.

New aporphine alkaloids from guatteria foliosa.

Mahiou V, Roblot F, Hocquemiller R, Cavé A, Rojas de Arias A, Inchausti A, Yaluff G, Fournet A, Angelo A.

J Nat Prod. 1994 Jul;57(7):890-5.

PMID:
7964785

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