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Items: 1 to 50 of 71

1.

A novel mutation in the NADH dehydrogenase (ubiquinone) 1 alpha sub-complex 4 (Ndufa4) gene links mitochondrial dysfunction to the development of diabetes in a rodent model.

Yagil C, Varadi-Levi R, Yagil Y.

Dis Model Mech. 2018 Oct 25. pii: dmm.036699. doi: 10.1242/dmm.036699. [Epub ahead of print]

2.

[THE ISRAELI RAT GENOME CENTER].

Yagil Y, Yagil C.

Harefuah. 2016 Aug;155(8):501-505. Review. Hebrew.

PMID:
28530328
3.

Three interacting genomic loci incorporating two novel mutations underlie the evolution of diet-induced diabetes.

Yagil Y, Markus B, Kohen R, Yagil C.

Mol Med. 2016 Oct;22:560-569. doi: 10.2119/molmed.2016.00114. Epub 2016 Jul 26.

4.

Macrophages dictate the progression and manifestation of hypertensive heart disease.

Kain D, Amit U, Yagil C, Landa N, Naftali-Shani N, Molotski N, Aviv V, Feinberg MS, Goitein O, Kushnir T, Konen E, Epstein FH, Yagil Y, Leor J.

Int J Cardiol. 2016 Jan 15;203:381-95. doi: 10.1016/j.ijcard.2015.10.126. Epub 2015 Oct 19.

PMID:
26539962
5.

Unmasking of proteinuria in the course of genetic dissection of nonproteinuric diabetic nephropathy.

Yagil Y, Roif D, Sapojnikov M, Ben-Dor D, Tobar A, Rosenmann E, Yagil C.

Physiol Genomics. 2014 Jan 1;46(1):29-38. doi: 10.1152/physiolgenomics.00133.2013. Epub 2013 Nov 5.

PMID:
24192394
6.

Geno-transcriptomic dissection of proteinuria in the uninephrectomized rat uncovers a molecular complexity with sexual dimorphism.

Yagil Y, Hessner M, Schulz H, Gosele C, Lebedev L, Barkalifa R, Sapojnikov M, Hubner N, Yagil C.

Physiol Genomics. 2010 Nov 29;42A(4):301-16. doi: 10.1152/physiolgenomics.00149.2010. Epub 2010 Sep 28.

PMID:
20876844
7.

Sex-specific genetic dissection of diabetes in a rodent model identifies Ica1 and Ndufa4 as major candidate genes.

Barkalifa R, Yagil Y, Yagil C.

Physiol Genomics. 2010 Aug;42(3):445-55. doi: 10.1152/physiolgenomics.00042.2010. Epub 2010 Jun 8.

PMID:
20530722
8.

Tumor necrosis factor-alpha: a possible priming agent for the polymorphonuclear leukocyte-reduced nicotinamide-adenine dinucleotide phosphate oxidase in hypertension.

Mazor R, Itzhaki O, Sela S, Yagil Y, Cohen-Mazor M, Yagil C, Kristal B.

Hypertension. 2010 Feb;55(2):353-62. doi: 10.1161/HYPERTENSIONAHA.109.144154. Epub 2010 Jan 11.

PMID:
20065151
9.

Genomic research in rat models of kidney disease.

Yagil Y, Yagil C.

Methods Mol Biol. 2010;597:427-44. doi: 10.1007/978-1-60327-389-3_29. Review.

PMID:
20013250
10.

ACE2 expression and activity are enhanced during pregnancy.

Levy A, Yagil Y, Bursztyn M, Barkalifa R, Scharf S, Yagil C.

Am J Physiol Regul Integr Comp Physiol. 2008 Dec;295(6):R1953-61. doi: 10.1152/ajpregu.90592.2008. Epub 2008 Oct 22.

11.

Early blood pressure-independent cardiac changes in diabetic rats.

Landau D, Chayat C, Zucker N, Golomb E, Yagil C, Yagil Y, Segev Y.

J Endocrinol. 2008 Apr;197(1):75-83. doi: 10.1677/JOE-08-0040.

PMID:
18372234
12.

Impaired glucose-stimulated insulin secretion is coupled with exocrine pancreatic lesions in the Cohen diabetic rat.

Weksler-Zangen S, Raz I, Lenzen S, Jörns A, Ehrenfeld S, Amir G, Oprescu A, Yagil Y, Yagil C, Zangen DH, Kaiser N.

Diabetes. 2008 Feb;57(2):279-87. Epub 2007 Oct 31.

13.

The polymorphonuclear leukocyte contributes to the development of hypertension in the Sabra rat.

Mazor R, Kristal B, Cohen-Mazor M, Yagil C, Yagil Y, Sela S.

J Hypertens. 2007 Nov;25(11):2249-56.

PMID:
17921819
14.

Peroxisome proliferator-activated receptor alpha: friend or foe?

Yagil C, Yagil Y.

Hypertension. 2007 Nov;50(5):847-50. Epub 2007 Oct 1. No abstract available.

PMID:
17909117
15.

Metabolic and genomic dissection of diabetes in the Cohen rat.

Yagil C, Barkalifa R, Sapojnikov M, Wechsler A, Ben-Dor D, Weksler-Zangen S, Kaiser N, Raz I, Yagil Y.

Physiol Genomics. 2007 Apr 24;29(2):181-92. Epub 2007 Jan 9.

PMID:
17213368
16.

Adducin and microalbuminuria: a complex association.

Yagil Y, Yagil C.

J Hypertens. 2006 May;24(5):819-20. No abstract available.

PMID:
16612241
17.
18.

Integration--a key to success in the genetic dissection of complex diseases?

Yagil Y, Yagil C.

Trends Cardiovasc Med. 2006 Feb;16(2):35-8. Review.

PMID:
16473759
19.

Genetic dissection of proteinuria in the Sabra rat.

Yagil C, Sapojnikov M, Wechsler A, Korol A, Yagil Y.

Physiol Genomics. 2006 Mar 13;25(1):121-33. Epub 2006 Jan 3.

PMID:
16390874
20.

Novel integrative approaches to the identification of candidate genes in hypertension.

Hubner N, Yagil C, Yagil Y.

Hypertension. 2006 Jan;47(1):1-5. Epub 2005 Dec 12. Review.

PMID:
16344362
21.

Estrogen-related genes and blood pressure: an example of the complexity of advanced association studies.

Yagil Y, Yagil C.

J Hypertens. 2005 Dec;23(12):2147-9. No abstract available.

PMID:
16269954
22.

Nonproteinuric diabetes-associated nephropathy in the Cohen rat model of type 2 diabetes.

Yagil C, Barak A, Ben-Dor D, Rosenmann E, Bernheim J, Rosner M, Segev Y, Weksler-Zangen S, Raz I, Yagil Y.

Diabetes. 2005 May;54(5):1487-96.

23.

Identification of hypertension-related genes through an integrated genomic-transcriptomic approach.

Yagil C, Hubner N, Monti J, Schulz H, Sapojnikov M, Luft FC, Ganten D, Yagil Y.

Circ Res. 2005 Apr 1;96(6):617-25. Epub 2005 Feb 24.

PMID:
15731461
24.

The search for the genetic basis of hypertension.

Yagil Y, Yagil C.

Curr Opin Nephrol Hypertens. 2005 Mar;14(2):141-7. Review.

PMID:
15687840
25.

Primed polymorphonuclear leukocytes, oxidative stress, and inflammation antecede hypertension in the Sabra rat.

Sela S, Mazor R, Amsalam M, Yagil C, Yagil Y, Kristal B.

Hypertension. 2004 Nov;44(5):764-9. Epub 2004 Sep 27.

PMID:
15452031
26.

Is it essential to change the term "essential hypertension"?

Yagil Y, Yagil C.

Hypertension. 2004 Nov;44(5):e7; author reply e7. Epub 2004 Sep 27. No abstract available.

PMID:
15452022
27.

Candidate genes, association studies and haplotype analysis in the search for the genetic basis of hypertension.

Yagil Y, Yagil C.

J Hypertens. 2004 Jul;22(7):1255-8. Review. No abstract available.

PMID:
15201538
28.

Congenics in the pathway from quantitative trait loci detection to gene identification: is that the way to go?

Yagil Y, Yagil C.

J Hypertens. 2003 Nov;21(11):2009-11. No abstract available.

PMID:
14597840
29.

Nephroprotective effects of the endothelin ET(A) receptor antagonist darusentan in salt-sensitive genetic hypertension.

Rothermund L, Traupe T, Dieterich M, Kossmehl P, Yagil C, Yagil Y, Kreutz R.

Eur J Pharmacol. 2003 May 16;468(3):209-16.

PMID:
12754059
30.

Pharmacogenomic considerations for immunosuppressive therapy.

Yagil Y, Yagil C.

Pharmacogenomics. 2003 May;4(3):309-19. Review.

PMID:
12718721
31.

Hypothesis: ACE2 modulates blood pressure in the mammalian organism.

Yagil Y, Yagil C.

Hypertension. 2003 Apr;41(4):871-3. Epub 2003 Mar 24. No abstract available.

PMID:
12654716
32.

Problems with linkage analysis and QTL detection in hypertension.

Yagil Y, Yagil C.

J Hypertens. 2003 Feb;21(2):247-9. No abstract available.

PMID:
12569247
33.

Congenic strains confirm the presence of salt-sensitivity QTLs on chromosome 1 in the Sabra rat model of hypertension.

Yagil C, Hubner N, Kreutz R, Ganten D, Yagil Y.

Physiol Genomics. 2003 Jan 15;12(2):85-95.

PMID:
12441404
34.

Endothelin-A receptor blockade prevents left ventricular hypertrophy and dysfunction in salt-sensitive experimental hypertension.

Rothermund L, Vetter R, Dieterich M, Kossmehl P, Gögebakan O, Yagil C, Yagil Y, Kreutz R.

Circulation. 2002 Oct 29;106(18):2305-8.

PMID:
12403658
35.

Insights into pharmacogenomics and its impact upon immunosuppressive therapy.

Yagil Y, Yagil C.

Transpl Immunol. 2002 May;9(2-4):203-9. Review.

PMID:
12180832
36.

Angiotensin-converting enzyme 2 is an essential regulator of heart function.

Crackower MA, Sarao R, Oudit GY, Yagil C, Kozieradzki I, Scanga SE, Oliveira-dos-Santos AJ, da Costa J, Zhang L, Pei Y, Scholey J, Ferrario CM, Manoukian AS, Chappell MC, Backx PH, Yagil Y, Penninger JM.

Nature. 2002 Jun 20;417(6891):822-8.

PMID:
12075344
37.

Proteinuria and glomerulosclerosis in the Sabra genetic rat model of salt susceptibility.

Yagil C, Sapojnikov M, Katni G, Ilan Z, Zangen SW, Rosenmann E, Yagil Y.

Physiol Genomics. 2002;9(3):167-78. Epub 2002 Apr 23.

PMID:
12045297
38.

The newly inbred cohen diabetic rat: a nonobese normolipidemic genetic model of diet-induced type 2 diabetes expressing sex differences.

Weksler-Zangen S, Yagil C, Zangen DH, Ornoy A, Jacob HJ, Yagil Y.

Diabetes. 2001 Nov;50(11):2521-9.

39.

Impaired function of endothelial pressure-activated cation channel in salt-sensitive genetic hypertension.

Köhler R, Kreutz R, Grundig A, Rothermund L, Yagil C, Yagil Y, Pries AR, Hoyer J.

J Am Soc Nephrol. 2001 Aug;12(8):1624-9.

41.

Genetic models of hypertension in experimental animals.

Yagil Y, Yagil C.

Exp Nephrol. 2001;9(1):1-9. Review.

PMID:
11053974
42.

[Angiotensin converting enzyme (ACE) gene polymorphism in a diabetic cohort and diabetic nephropathy].

Levinson O, Oren S, Yagil C, Sapojnikov M, Wechsler A, Bloch R, Yagil Y.

Harefuah. 1999 May 16;136(10):768-73, 843. Hebrew.

PMID:
10955109
43.

Regulation by sodium intake of type 1 angiotensin II receptor mRNAs in the kidney of Sabra rats.

Nicco C, Martin H, Yagil C, Yagil Y, Bankir L, Bouby N.

J Hypertens. 2000 Aug;18(8):1097-105.

PMID:
10954002
44.

Farnesol blocks the L-type Ca2+ channel by targeting the alpha 1C subunit.

Luft UC, Bychkov R, Gollasch M, Gross V, Roullet JB, McCarron DA, Ried C, Hofmann F, Yagil Y, Yagil C, Haller H, Luft FC.

Arterioscler Thromb Vasc Biol. 1999 Apr;19(4):959-66. Erratum in: Arterioscler Thromb Vasc Biol 1999 Oct;19(10):2579.

PMID:
10195923
45.

Role of chromosome X in the Sabra rat model of salt-sensitive hypertension.

Yagil C, Sapojnikov M, Kreutz R, Zürcher H, Ganten D, Yagil Y.

Hypertension. 1999 Jan;33(1 Pt 2):261-5.

PMID:
9931114
46.
47.

Genetic basis of salt-susceptibility in the Sabra rat model of hypertension.

Yagil Y, Yagil C.

Kidney Int. 1998 Jun;53(6):1493-500. Review.

48.

Salt susceptibility maps to chromosomes 1 and 17 with sex specificity in the Sabra rat model of hypertension.

Yagil C, Sapojnikov M, Kreutz R, Katni G, Lindpaintner K, Ganten D, Yagil Y.

Hypertension. 1998 Jan;31(1):119-24.

PMID:
9449402
49.

Nitric oxide synthase and renin-angiotensin system gene expression in salt-sensitive and salt-resistant Sabra rats.

Lippoldt A, Gross V, Schneider K, Hansson A, Nadaud S, Schneider W, Bader M, Yagil C, Yagil Y, Luft FC.

Hypertension. 1997 Sep;30(3 Pt 1):409-15.

PMID:
9314425
50.

Pressure natriuresis in salt-sensitive and salt-resistant Sabra rats.

Gross V, Lippoldt A, Yagil C, Yagil Y, Luft FC.

Hypertension. 1997 Jun;29(6):1252-9.

PMID:
9180625

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