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Items: 24


Bridging the Gap: Modulatory Roles of the Grb2-Family Adaptor, Gads, in Cellular and Allergic Immune Responses.

Yablonski D.

Front Immunol. 2019 Jul 25;10:1704. doi: 10.3389/fimmu.2019.01704. eCollection 2019. Review.


Dimerization of the adaptor Gads facilitates antigen receptor signaling by promoting the cooperative binding of Gads to the adaptor LAT.

Sukenik S, Frushicheva MP, Waknin-Lellouche C, Hallumi E, Ifrach T, Shalah R, Beach D, Avidan R, Oz I, Libman E, Aronheim A, Lewinson O, Yablonski D.

Sci Signal. 2017 Sep 26;10(498). pii: eaal1482. doi: 10.1126/scisignal.aal1482.


The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells.

Dufner A, Kisser A, Niendorf S, Basters A, Reissig S, Schönle A, Aichem A, Kurz T, Schlosser A, Yablonski D, Groettrup M, Buch T, Waisman A, Schamel WW, Prinz M, Knobeloch KP.

Nat Immunol. 2015 Sep;16(9):950-60. doi: 10.1038/ni.3230. Epub 2015 Jul 27.


Modulation of TCR responsiveness by the Grb2-family adaptor, Gads.

Lugassy J, Corso J, Beach D, Petrik T, Oellerich T, Urlaub H, Yablonski D.

Cell Signal. 2015 Jan;27(1):125-34. doi: 10.1016/j.cellsig.2014.10.005. Epub 2014 Oct 23.


Release of serine/threonine-phosphorylated adaptors from signaling microclusters down-regulates T cell activation.

Lasserre R, Cuche C, Blecher-Gonen R, Libman E, Biquand E, Danckaert A, Yablonski D, Alcover A, Di Bartolo V.

J Cell Biol. 2011 Nov 28;195(5):839-53. doi: 10.1083/jcb.201103105. Epub 2011 Nov 21.


The Challenges of Writing Portable, Correct and High Performance Libraries for GPUs.

Leeser M, Yablonski D, Brooks D, King LS.

Comput Archit News. 2011 Sep 1;39(4):2-7.


Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells.

Sela M, Bogin Y, Beach D, Oellerich T, Lehne J, Smith-Garvin JE, Okumura M, Starosvetsky E, Kosoff R, Libman E, Koretzky G, Kambayashi T, Urlaub H, Wienands J, Chernoff J, Yablonski D.

EMBO J. 2011 Jul 1;30(15):3160-72. doi: 10.1038/emboj.2011.213.


Src homology 2-domain containing leukocyte-specific phosphoprotein of 76 kDa is mandatory for TCR-mediated inside-out signaling, but dispensable for CXCR4-mediated LFA-1 activation, adhesion, and migration of T cells.

Horn J, Wang X, Reichardt P, Stradal TE, Warnecke N, Simeoni L, Gunzer M, Yablonski D, Schraven B, Kliche S.

J Immunol. 2009 Nov 1;183(9):5756-67. doi: 10.4049/jimmunol.0900649. Epub 2009 Oct 7.


SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK.

Bogin Y, Ainey C, Beach D, Yablonski D.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6638-43. Epub 2007 Apr 9.


Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.

Weisz Hubsman M, Volinsky N, Manser E, Yablonski D, Aronheim A.

Biochem J. 2007 Jun 15;404(3):487-97.


Dual role of SLP-76 in mediating T cell receptor-induced activation of phospholipase C-gamma1.

Beach D, Gonen R, Bogin Y, Reischl IG, Yablonski D.

J Biol Chem. 2007 Feb 2;282(5):2937-46. Epub 2006 Dec 4.


T cell receptor-induced activation of phospholipase C-gamma1 depends on a sequence-independent function of the P-I region of SLP-76.

Gonen R, Beach D, Ainey C, Yablonski D.

J Biol Chem. 2005 Mar 4;280(9):8364-70. Epub 2004 Dec 28.


Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes.

Sauer K, Liou J, Singh SB, Yablonski D, Weiss A, Perlmutter RM.

J Biol Chem. 2001 Nov 30;276(48):45207-16. Epub 2001 Aug 3.


The adapter proteins LAT and SLP-76 are required for T-cell activation.

Finco TS, Yablonski D, Lin J, Weiss A.

Cold Spring Harb Symp Quant Biol. 1999;64:265-74. Review. No abstract available.


A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.

Ku GM, Yablonski D, Manser E, Lim L, Weiss A.

EMBO J. 2001 Feb 1;20(3):457-65.


The Src kinase p56(lck) up-regulates VLA-4 integrin affinity. Implications for rapid spontaneous and chemokine-triggered T cell adhesion to VCAM-1 and fibronectin.

Feigelson SW, Grabovsky V, Winter E, Chen LL, Pepinsky RB, Yednock T, Yablonski D, Lobb R, Alon R.

J Biol Chem. 2001 Apr 27;276(17):13891-901. Epub 2000 Dec 1.


Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell.

Yablonski D, Kuhne MR, Kadlecek T, Weiss A.

Science. 1998 Jul 17;281(5375):413-6.


Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction.

Yablonski D, Marbach I, Levitzki A.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13864-9.


Cloning of the STE5 gene of Saccharomyces cerevisiae as a suppressor of the mating defect of cdc25 temperature-sensitive mutants.

Perlman R, Yablonski D, Simchen G, Levitzki A.

Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5474-8.

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