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Items: 1 to 50 of 70

1.

Microwave-assisted synthesis and in vitro stability of N-benzylamide non-steroidal anti-inflammatory drug conjugates for CNS delivery.

Eden BD, Rice AJ, Lovett TD, Toner OM, Geissler EP, Bowman WE, Young SC.

Bioorg Med Chem Lett. 2019 Jun 15;29(12):1487-1491. doi: 10.1016/j.bmcl.2019.04.016. Epub 2019 Apr 8.

PMID:
30987893
2.

The Prevalence and Risk Factors of Gastric Polyp in Asymptomatic Patients Receiving Health Examination.

Wang FW, Young SC, Chen RY, Lin KH, Chen YH, Hsu PI, Yu HC.

Gastroenterol Res Pract. 2018 Dec 10;2018:9451905. doi: 10.1155/2018/9451905. eCollection 2018.

3.

Is it safe? The restraint chair compared to traditional methods of restraint: A three hospital study.

Visaggio N, Phillips KE, Kichefski K, McElhinney J, Idiculla TB, Blair EW, Johnson R, Santaniello J, Pennant LRA, Young SC.

Arch Psychiatr Nurs. 2018 Oct;32(5):723-728. doi: 10.1016/j.apnu.2018.04.003. Epub 2018 Apr 16. No abstract available.

PMID:
30201200
4.
5.

Sulfur mustard induced mast cell degranulation in mouse skin is inhibited by a novel anti-inflammatory and anticholinergic bifunctional prodrug.

Joseph LB, Composto GM, Perez RM, Kim HD, Casillas RP, Heindel ND, Young SC, Lacey CJ, Saxena J, Guillon CD, Croutch CR, Laskin JD, Heck DE.

Toxicol Lett. 2018 Sep 1;293:77-81. doi: 10.1016/j.toxlet.2017.11.005. Epub 2017 Nov 7.

PMID:
29127031
6.

Recommendations for Best Disinfectant Practices to Reduce the Spread of Infection via Wrestling Mats.

Young LM, Motz VA, Markey ER, Young SC, Beaschler RE.

J Athl Train. 2017 Feb;52(2):82-88. doi: 10.4085/1062-6050-52.1.02. Epub 2017 Jan 16.

7.

Multi-inhibitor prodrug constructs for simultaneous delivery of anti-inflammatory agents to mustard-induced skin injury.

Lacey CJ, Wohlman I, Guillon C, Saxena J, Fianu-Velgus C, Aponte E, Young SC, Heck DE, Joseph LB, Laskin JD, Heindel ND.

Ann N Y Acad Sci. 2016 Aug;1378(1):174-179. doi: 10.1111/nyas.13177. Epub 2016 Aug 9. Review.

8.

Ethynylphenyl carbonates and carbamates as dual-action acetylcholinesterase inhibitors and anti-inflammatory agents.

Saxena J, Meloni D, Huang MT, Heck DE, Laskin JD, Heindel ND, Young SC.

Bioorg Med Chem Lett. 2015 Dec 1;25(23):5609-12. doi: 10.1016/j.bmcl.2015.10.039. Epub 2015 Oct 23.

9.

Isolation of a novel thermophilic Campylobacter from cases of spotty liver disease in laying hens and experimental reproduction of infection and microscopic pathology.

Crawshaw TR, Chanter JI, Young SC, Cawthraw S, Whatmore AM, Koylass MS, Vidal AB, Salguero FJ, Irvine RM.

Vet Microbiol. 2015 Sep 30;179(3-4):315-21. doi: 10.1016/j.vetmic.2015.06.008. Epub 2015 Jun 12.

PMID:
26130518
10.

Modulatory effects of bombyxin on ecdysteroidogenesis in Bombyx mori prothoracic glands.

Gu SH, Chen CH, Hsieh YC, Lin PL, Young SC.

J Insect Physiol. 2015 Jan;72:61-69. doi: 10.1016/j.jinsphys.2014.11.007. Epub 2014 Dec 8.

PMID:
25497117
11.

Therapeutic potential of a non-steroidal bifunctional anti-inflammatory and anti-cholinergic agent against skin injury induced by sulfur mustard.

Chang YC, Wang JD, Hahn RA, Gordon MK, Joseph LB, Heck DE, Heindel ND, Young SC, Sinko PJ, Casillas RP, Laskin JD, Laskin DL, Gerecke DR.

Toxicol Appl Pharmacol. 2014 Oct 15;280(2):236-44. doi: 10.1016/j.taap.2014.07.016. Epub 2014 Aug 13.

12.

Leadership and teamwork in medical emergencies: performance of nursing students and registered nurses in simulated patient scenarios.

Endacott R, Bogossian FE, Cooper SJ, Forbes H, Kain VJ, Young SC, Porter JE; First2Act Team.

J Clin Nurs. 2015 Jan;24(1-2):90-100. doi: 10.1111/jocn.12611. Epub 2014 Jun 4.

PMID:
24898949
13.
14.

Back-scattering interferometry: an ultrasensitive method for the unperturbed detection of acetylcholinesterase-inhibitor interactions.

Haddad GL, Young SC, Heindel ND, Bornhop DJ, Flowers RA 2nd.

Angew Chem Int Ed Engl. 2012 Oct 29;51(44):11126-30. doi: 10.1002/anie.201203640. Epub 2012 Oct 4.

15.

An unusual case of foreskin phimosis after radiotherapy for rectal carcinoma.

Nair RG, Bensadoun RJ, Oberholzer T, Gopalan V, Young SC, Joubert W.

Cancer Radiother. 2012 Jul-Aug;16(4):292-4. doi: 10.1016/j.canrad.2012.03.007. Epub 2012 Jun 19.

PMID:
22721756
16.

Leveraging EDI files to improve your revenue cycle.

Young SC.

Revenue-cycle Strateg. 2011 Nov;8(9):6-7. No abstract available.

PMID:
22299541
17.

TOR signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori.

Gu SH, Yeh WL, Young SC, Lin PL, Li S.

Insect Biochem Mol Biol. 2012 Apr;42(4):296-303. doi: 10.1016/j.ibmb.2011.12.010. Epub 2011 Dec 31.

PMID:
22227406
18.

Transcriptional regulation of the PTTH receptor in prothoracic glands of the silkworm, Bombyx mori.

Young SC, Yeh WL, Gu SH.

J Insect Physiol. 2012 Jan;58(1):102-9. doi: 10.1016/j.jinsphys.2011.10.005. Epub 2011 Nov 6.

PMID:
22085674
19.

Involvement of 4E-BP phosphorylation in embryonic development of the silkworm, Bombyx mori.

Gu SH, Young SC, Tsai WH, Lin JL, Lin PL.

J Insect Physiol. 2011 Jul;57(7):978-85. doi: 10.1016/j.jinsphys.2011.04.014. Epub 2011 May 12.

PMID:
21600900
20.

Discovery of potent and selective inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents.

Charrier JD, Durrant SJ, Golec JM, Kay DP, Knegtel RM, MacCormick S, Mortimore M, O'Donnell ME, Pinder JL, Reaper PM, Rutherford AP, Wang PS, Young SC, Pollard JR.

J Med Chem. 2011 Apr 14;54(7):2320-30. doi: 10.1021/jm101488z. Epub 2011 Mar 17.

PMID:
21413798
21.

Investigation of anticholinergic and non-steroidal anti-inflammatory prodrugs which reduce chemically induced skin inflammation.

Young SC, Fabio KM, Huang MT, Saxena J, Harman MP, Guillon CD, Vetrano AM, Heck DE, Flowers RA 2nd, Heindel ND, Laskin JD.

J Appl Toxicol. 2012 Feb;32(2):135-41. doi: 10.1002/jat.1645. Epub 2011 Feb 11.

22.

Involvement of PI3K/Akt signaling in PTTH-stimulated ecdysteroidogenesis by prothoracic glands of the silkworm, Bombyx mori.

Gu SH, Young SC, Lin JL, Lin PL.

Insect Biochem Mol Biol. 2011 Mar;41(3):197-202. doi: 10.1016/j.ibmb.2010.12.004. Epub 2011 Jan 1.

PMID:
21199670
23.

DNA damages induced by trans, trans-2,4-decadienal (tt-DDE), a component of cooking oil fume, in human bronchial epithelial cells.

Young SC, Chang LW, Lee HL, Tsai LH, Liu YC, Lin P.

Environ Mol Mutagen. 2010 May;51(4):315-21. doi: 10.1002/em.20550.

PMID:
20143344
24.

Inhibition of biliverdin reductase increases ANG II-dependent superoxide levels in cultured renal tubular epithelial cells.

Young SC, Storm MV, Speed JS, Kelsen S, Tiller CV, Vera T, Drummond HA, Stec DE.

Am J Physiol Regul Integr Comp Physiol. 2009 Nov;297(5):R1546-53. doi: 10.1152/ajpregu.90933.2008. Epub 2009 Sep 16.

25.

Apoptotic death mode of mitomycin C-treated HeLa cells and cellular localization of mitomycin C-induced P-glycoprotein.

Cheng MH, Cheng HT, Lin SS, Young SC, Pai CJ, Liao PH, Chen SC, Chou MY, Yang JJ, Yang CC.

Drug Chem Toxicol. 2009;32(2):158-68. doi: 10.1080/01480540802594491.

PMID:
19514952
26.

Review of 120 anal cancer patients.

Young SC, Solomon MJ, Hruby G, Frizelle FA.

Colorectal Dis. 2009 Nov;11(9):909-14. doi: 10.1111/j.1463-1318.2008.01723.x. Epub 2008 Oct 25.

PMID:
19175651
27.

The immunopharmaceutical effects and mechanisms of herb medicine.

Huang CF, Lin SS, Liao PH, Young SC, Yang CC.

Cell Mol Immunol. 2008 Feb;5(1):23-31. doi: 10.1038/cmi.2008.3. Review.

28.

Investigation of the terminal P4 domain in a series of D-phenylglycinamide-based factor Xa inhibitors.

Franciskovich JB, Masters JJ, Weber WW, Klimkowski VJ, Chouinard M, Sipes PR, Johnson LM, Snyder DW, Chastain MK, Craft TJ, Towner RD, Gifford-Moore DS, Froelich LL, Smallwood JK, Foster RS, Smith GF, Liebeschuetz JW, Murray CW, Young SC.

Bioorg Med Chem Lett. 2007 Dec 15;17(24):6910-3. Epub 2007 Oct 24.

PMID:
17976987
29.

Significant rising antibody titres to influenza A are associated with an acute reduction in milk yield in cattle.

Crawshaw TR, Brown IH, Essen SC, Young SC.

Vet J. 2008 Oct;178(1):98-102. Epub 2007 Sep 11.

PMID:
17851097
30.

Protection effect of piper betel leaf extract against carbon tetrachloride-induced liver fibrosis in rats.

Young SC, Wang CJ, Lin JJ, Peng PL, Hsu JL, Chou FP.

Arch Toxicol. 2007 Jan;81(1):45-55. Epub 2006 May 5.

PMID:
16676162
31.

Increased sensitivity of Hep G2 cells toward the cytotoxicity of cisplatin by the treatment of piper betel leaf extract.

Young SC, Wang CJ, Hsu JD, Hsu JL, Chou FP.

Arch Toxicol. 2006 Jun;80(6):319-27. Epub 2005 Dec 9.

PMID:
16341694
32.
33.

Benefits of surgical experience in a third-world country during residency.

Jacobs MJ, Young SC, Mittal VK.

Curr Surg. 2002 May-Jun;59(3):330-2.

PMID:
16093158
34.

Intestinal dilation in organic layers.

Twomey DF, Wood AM, Young SC.

Vet Rec. 2005 Jul 9;157(2):63-4. No abstract available.

PMID:
16006645
35.

Portal vein thrombosis: an unusual complication of laparoscopic cholecystectomy.

Preventza OA, Habib FA, Young SC, Penney D, Oppat W, Mittal VK.

JSLS. 2005 Jan-Mar;9(1):87-90.

36.

Defining the role of adjuvant therapy for locally advanced cancer of the pancreas.

Jacobs MJ, Mittal VK, ReMine SG, Young SC.

Curr Surg. 2004 Mar-Apr;61(2):125-30. No abstract available.

PMID:
15051249
37.

Differential induction of the expression of GST subunits by geniposide in rat hepatocytes.

Kuo WH, Wang CJ, Young SC, Sun YC, Chen YJ, Chou FP.

Pharmacology. 2004 Jan;70(1):15-22.

PMID:
14646352
38.

A four component coupling strategy for the synthesis of D-phenylglycinamide-derived non-covalent factor Xa inhibitors.

Sheehan SM, Masters JJ, Wiley MR, Young SC, Liebeschuetz JW, Jones SD, Murray CW, Franciskovich JB, Engel DB, Weber WW, Marimuthu J, Kyle JA, Smallwood JK, Farmen MW, Smith GF.

Bioorg Med Chem Lett. 2003 Jul 21;13(14):2255-9.

PMID:
12824013
39.

Plasticity and learning in a network of coupled phase oscillators.

Seliger P, Young SC, Tsimring LS.

Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Apr;65(4 Pt 1):041906. Epub 2002 Mar 26.

PMID:
12005872
40.

PRO_SELECT: combining structure-based drug design and array-based chemistry for rapid lead discovery. 2. The development of a series of highly potent and selective factor Xa inhibitors.

Liebeschuetz JW, Jones SD, Morgan PJ, Murray CW, Rimmer AD, Roscoe JM, Waszkowycz B, Welsh PM, Wylie WA, Young SC, Martin H, Mahler J, Brady L, Wilkinson K.

J Med Chem. 2002 Mar 14;45(6):1221-32.

PMID:
11881991
41.

Paget disease of the breast: analysis of 41 patients.

Fu W, Mittel VK, Young SC.

Am J Clin Oncol. 2001 Aug;24(4):397-400.

PMID:
11474272
42.

Molecular markers in Paget disease of the breast.

Fu W, Lobocki CA, Silberberg BK, Chelladurai M, Young SC.

J Surg Oncol. 2001 Jul;77(3):171-8.

PMID:
11455553
43.

The design of phenylglycine containing benzamidine carboxamides as potent and selective inhibitors of factor Xa.

Jones SD, Liebeschuetz JW, Morgan PJ, Murray CW, Rimmer AD, Roscoe JM, Waszkowycz B, Welsh PM, Wylie WA, Young SC, Martin H, Mahler J, Brady L, Wilkinson K.

Bioorg Med Chem Lett. 2001 Mar 12;11(5):733-6.

PMID:
11266180
44.

DNA binding, solubility, and partitioning characteristics of extended lexitropsins.

Fishleigh RV, Fox KR, Khalaf AI, Pitt AR, Scobie M, Suckling CJ, Urwin J, Waigh RD, Young SC.

J Med Chem. 2000 Aug 24;43(17):3257-66.

PMID:
10966744
45.

Carotid artery injuries and their management.

Mittal VK, Paulson TJ, Colaiuta E, Habib FA, Penney DG, Daly B, Young SC.

J Cardiovasc Surg (Torino). 2000 Jun;41(3):423-31.

PMID:
10952336
46.

Intracranial aneurysms.

Mittal VK, Habib FA, Soo T, Young SC.

Curr Surg. 2000 May 1;57(3):197-201. No abstract available.

PMID:
10930614
47.

Sentinel lymph node dissection for primary cutaneous melanoma: a community hospital's initial experience.

Habib FA, Lodish ME, Mittal VK, Young SC.

Am Surg. 2000 Mar;66(3):291-5.

PMID:
10759202
49.

Advantage of surgery and adjuvant chemotherapy in the treatment of primary gastrointestinal lymphoma.

Lin KM, Penney DG, Mahmoud A, Chae W, Kolachalam RB, Young SC.

J Surg Oncol. 1997 Mar;64(3):237-41.

PMID:
9121156
50.

PRO_SELECT: combining structure-based drug design and combinatorial chemistry for rapid lead discovery. 1. Technology.

Murray CW, Clark DE, Auton TR, Firth MA, Li J, Sykes RA, Waszkowycz B, Westhead DR, Young SC.

J Comput Aided Mol Des. 1997 Mar;11(2):193-207.

PMID:
9089436

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