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Directed evolution of a penicillin V acylase from Bacillus sphaericus to improve its catalytic efficiency for 6-APA production.

Xu G, Zhao Q, Huang B, Zhou J, Cao F.

Enzyme Microb Technol. 2018 Dec;119:65-70. doi: 10.1016/j.enzmictec.2018.08.006. Epub 2018 Aug 24.


POSTAR2: deciphering the post-transcriptional regulatory logics.

Zhu Y, Xu G, Yang YT, Xu Z, Chen X, Shi B, Xie D, Lu ZJ, Wang P.

Nucleic Acids Res. 2018 Sep 17. doi: 10.1093/nar/gky830. [Epub ahead of print]


Hydrogen Sulfide-Activatable Second Near-Infrared Fluorescent Nanoassemblies for Targeted Photothermal Cancer Therapy.

Shi B, Yan Q, Tang J, Xin K, Zhang J, Zhu Y, Xu G, Wang R, Chen J, Gao W, Zhu T, Shi J, Fan C, Zhao C, Tian H.

Nano Lett. 2018 Sep 21. doi: 10.1021/acs.nanolett.8b02767. [Epub ahead of print]


In vitro Prebiotic Effects of Bamboo Shoots and Potato Peel Extracts on the Proliferation of Lactic Acid Bacteria Under Simulated GIT Conditions.

Thakur K, Xu GY, Zhang JG, Zhang F, Hu F, Wei ZJ.

Front Microbiol. 2018 Sep 5;9:2114. doi: 10.3389/fmicb.2018.02114. eCollection 2018.


[Effect of Electroacupuncture at Different Acupoints on Steroid Hormones and Ovarian Androgen Receptor Expression in Polycystic Ovary Syndrome Rats].

Xu G, Wang Q, Zhang AD, Liu JD, Feng JW, Chen YL.

Zhen Ci Yan Jiu. 2018 Sep 25;43(9):543-9. doi: 10.13702/j.1000-0607.170688. Chinese.


Factors affecting the live-birth rate in women with diminished ovarian reserve undergoing IVF-ET.

Huang Y, Li J, Zhang F, Liu Y, Xu G, Guo J, Zhang R, Wu Y, Liu J, Chen K, Zhao W, Wu W, Hu Y, Chen G, Zhang D.

Arch Gynecol Obstet. 2018 Sep 19. doi: 10.1007/s00404-018-4884-4. [Epub ahead of print]


Cost-effectiveness Analysis of Two Therapeutic Regimens for Newly Diagnosed Smear-negative Pulmonary Tuberculosis.

Chen L, Mei JZ, Chen XX, Feng HY, Wang JW, Li HC, Xu GH, Xiao LW, Huang YX, Zhou L.

Biomed Environ Sci. 2018 Aug;31(8):623-626. doi: 10.3967/bes2018.085. No abstract available.


[Effect of Straw Residues in Combination with Reduced Fertilization Rate on Greenhouse Gas Emissions from a Vegetable Field].

Huang R, Gao M, Li JC, Xu GX, Lü S, Luo M.

Huan Jing Ke Xue. 2018 Oct 8;39(10):4694-4704. doi: 10.13227/j.hjkx.201802087. Chinese.


Lysines 207 and 325 methylation of WDR5 catalyzed by SETD6 promotes breast cancer cell proliferation and migration.

Yao R, Wang Y, Han D, Ma Y, Ma M, Zhao Y, Tan J, Lu J, Xu G, Li X.

Oncol Rep. 2018 Nov;40(5):3069-3077. doi: 10.3892/or.2018.6669. Epub 2018 Aug 23.


Microglia enhanced the angiogenesis, migration and proliferation of co-cultured RMECs.

Ding X, Gu R, Zhang M, Ren H, Shu Q, Xu G, Wu H.

BMC Ophthalmol. 2018 Sep 17;18(1):249. doi: 10.1186/s12886-018-0886-z.


Stepwise cis-Regulatory Changes in ZCN8 Contribute to Maize Flowering-Time Adaptation.

Guo L, Wang X, Zhao M, Huang C, Li C, Li D, Yang CJ, York AM, Xue W, Xu G, Liang Y, Chen Q, Doebley JF, Tian F.

Curr Biol. 2018 Sep 10. pii: S0960-9822(18)30928-X. doi: 10.1016/j.cub.2018.07.029. [Epub ahead of print]


A cross-sectional study of the relationship between sexual compulsivity and unprotected anal intercourse among men who have sex with men in shanghai, China.

Wang X, Wang Z, Jiang X, Li R, Wang Y, Xu G, Zou H, Cai Y.

BMC Infect Dis. 2018 Sep 15;18(1):465. doi: 10.1186/s12879-018-3360-x.


Coordinated biosynthesis of the purine nucleoside antibiotics aristeromycin and coformycin in the actinomycetes.

Xu G, Kong L, Gong R, Xu L, Gao Y, Jiang M, Cai YS, Hong K, Hu Y, Liu P, Deng Z, Price NPJ, Chen W.

Appl Environ Microbiol. 2018 Sep 14. pii: AEM.01860-18. doi: 10.1128/AEM.01860-18. [Epub ahead of print]


Erratum: Expression and association of VEGF-Notch pathways in infantile hemangiomas.

Li S, Xu G, Gao F, Bi J, Huo R.

Exp Ther Med. 2018 Oct;16(4):3752. doi: 10.3892/etm.2018.6529. Epub 2018 Jul 26.


Antitumor effects of nadroparin combined with radiotherapy in Lewis lung cancer models.

Zhuang X, Qiao T, Yuan S, Zhang Q, Chen W, Luo Y, Xu G.

Onco Targets Ther. 2018 Aug 24;11:5133-5142. doi: 10.2147/OTT.S176526. eCollection 2018.


A Zr(IV)-based porphyrinic metal-organic framework as a solid-phase sorbent for extraction of sulfonamides prior to their quantitation by LC-MS.

Deng ZH, Xu GJ, Wang XL, Wang X, Wang ML, Lin JM, Zhao RS.

Mikrochim Acta. 2018 Sep 12;185(10):450. doi: 10.1007/s00604-018-2985-1.


Human-Biting Ixodes Ticks and Pathogen Prevalence from California, Oregon, and Washington.

Xu G, Pearson P, Dykstra E, Andrews ES, Rich SM.

Vector Borne Zoonotic Dis. 2018 Sep 12. doi: 10.1089/vbz.2018.2323. [Epub ahead of print]


Effect of ionic strength on bioaccumulation and toxicity of silver nanoparticles in Caenorhabditis elegans.

Yang Y, Xu G, Xu S, Chen S, Xu A, Wu L.

Ecotoxicol Environ Saf. 2018 Sep 8;165:291-298. doi: 10.1016/j.ecoenv.2018.09.008. [Epub ahead of print]


The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers.

Razavi P, Chang MT, Xu G, Bandlamudi C, Ross DS, Vasan N, Cai Y, Bielski CM, Donoghue MTA, Jonsson P, Penson A, Shen R, Pareja F, Kundra R, Middha S, Cheng ML, Zehir A, Kandoth C, Patel R, Huberman K, Smyth LM, Jhaveri K, Modi S, Traina TA, Dang C, Zhang W, Weigelt B, Li BT, Ladanyi M, Hyman DM, Schultz N, Robson ME, Hudis C, Brogi E, Viale A, Norton L, Dickler MN, Berger MF, Iacobuzio-Donahue CA, Chandarlapaty S, Scaltriti M, Reis-Filho JS, Solit DB, Taylor BS, Baselga J.

Cancer Cell. 2018 Sep 10;34(3):427-438.e6. doi: 10.1016/j.ccell.2018.08.008.


A "Triple Trouble" Case of Facioscapulohumeral Muscular Dystrophy Accompanied by Peripheral Neuropathy and Myoclonic Epilepsy.

Lin XD, He JJ, Lin F, Chen HZ, Xu LQ, Hu W, Cai NQ, Lin MT, Wang N, Wang ZQ, Xu GR.

Chin Med J (Engl). 2018 Sep 20;131(18):2164-2171. doi: 10.4103/0366-6999.240797.


Signaling specificity in the c-di-GMP-dependent network regulating antibiotic synthesis in Lysobacter.

Xu G, Han S, Huo C, Chin KH, Chou SH, Gomelsky M, Qian G, Liu F.

Nucleic Acids Res. 2018 Sep 7. doi: 10.1093/nar/gky803. [Epub ahead of print]


Comparative proteomic analysis of maternal peripheral plasma and umbilical venous plasma from normal and gestational diabetes mellitus pregnancies.

Liao Y, Xu GF, Jiang Y, Zhu H, Sun LJ, Peng R, Luo Q.

Medicine (Baltimore). 2018 Sep;97(36):e12232. doi: 10.1097/MD.0000000000012232.


The roles of IL-6, IL-8 and IL-10 gene polymorphisms in gastric cancer: A meta-analysis.

Wang X, Yang F, Xu G, Zhong S.

Cytokine. 2018 Sep 6;111:230-236. doi: 10.1016/j.cyto.2018.08.024. [Epub ahead of print]


Low-concentration BPF induced cell biological responses by the ERα and GPER1-mediated signaling pathways in MCF-7 breast cancer cells.

Lei B, Huang Y, Liu Y, Xu J, Sun S, Zhang X, Xu G, Wu M, Yu Y, Feng C.

Ecotoxicol Environ Saf. 2018 Sep 5;165:144-152. doi: 10.1016/j.ecoenv.2018.08.102. [Epub ahead of print]


Observation of the Semileptonic Decay D^{0}→a_{0}(980)^{-}e^{+}ν_{e} and Evidence for D^{+}→a_{0}(980)^{0}e^{+}ν_{e}.

Ablikim M, Achasov MN, Ahmed S, Albrecht M, Alekseev M, Amoroso A, An FF, An Q, Bai Y, Bakina O, Baldini Ferroli R, Ban Y, Begzsuren K, Bennett DW, Bennett JV, Berger N, Bertani M, Bettoni D, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Calcaterra A, Cao GF, Cetin SA, Chai J, Chang JF, Chang WL, Chelkov G, Chen G, Chen HS, Chen JC, Chen ML, Chen SJ, Chen XR, Chen YB, Cheng W, Chu XK, Cibinetto G, Cossio F, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Fan JZ, Fang J, Fang SS, Fang Y, Farinelli R, Fava L, Feldbauer F, Felici G, Feng CQ, Fritsch M, Fu CD, Gao Q, Gao XL, Gao Y, Gao YG, Gao Z, Garillon B, Garzia I, Gilman A, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu LM, Gu MH, Gu YT, Guo AQ, Guo LB, Guo RP, Guo YP, Guskov A, Haddadi Z, Han S, Hao XQ, Harris FA, He KL, Heinsius FH, Held T, Heng YK, Hou ZL, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang XZ, Huang ZL, Hussain T, Ikegami Andersson W, Imoehl W, Irshad M, Ji Q, Ji QP, Ji XB, Ji XL, Jiang HL, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Jin Y, Johansson T, Kalantar-Nayestanaki N, Kang XS, Kavatsyuk M, Ke BC, Keshk IK, Khan T, Khoukaz A, Kiese P, Kiuchi R, Kliemt R, Koch L, Kolcu OB, Kopf B, Kuemmel M, Kuessner M, Kupsc A, Kurth M, Kühn W, Lange JS, Larin P, Lavezzi L, Leiber S, Leithoff H, Li C, Li C, Li DM, Li F, Li FY, Li G, Li HB, Li HJ, Li JC, Li JW, Li KJ, Li K, Li K, Li LK, Li L, Li PL, Li PR, Li QY, Li WD, Li WG, Li XL, Li XN, Li XQ, Li ZB, Liang H, Liang YF, Liang YT, Liao GR, Liao LZ, Libby J, Lin CX, Lin DX, Liu B, Liu BJ, Liu CX, Liu D, Liu DY, Liu FH, Liu F, Liu F, Liu HB, Liu HL, Liu HM, Liu H, Liu H, Liu JB, Liu JY, Liu KY, Liu K, Liu LD, Liu Q, Liu SB, Liu X, Liu YB, Liu ZA, Liu Z, Long YF, Lou XC, Lu HJ, Lu JG, Lu Y, Lu YP, Luo CL, Luo MX, Luo PW, Luo T, Luo XL, Lusso S, Lyu XR, Ma FC, Ma HL, Ma LL, Ma MM, Ma QM, Ma XN, Ma XY, Ma YM, Maas FE, Maggiora M, Maldaner S, Malik QA, Mangoni A, Mao YJ, Mao ZP, Marcello S, Meng ZX, Messchendorp JG, Mezzadri G, Min J, Min TJ, Mitchell RE, Mo XH, Mo YJ, Morales Morales C, Muchnoi NY, Muramatsu H, Mustafa A, Nakhoul S, Nefedov Y, Nerling F, Nikolaev IB, Ning Z, Nisar S, Niu SL, Niu XY, Olsen SL, Ouyang Q, Pacetti S, Pan Y, Papenbrock M, Patteri P, Pelizaeus M, Pellegrino J, Peng HP, Peng ZY, Peters K, Pettersson J, Ping JL, Ping RG, Pitka A, Poling R, Prasad V, Qi M, Qi TY, Qian S, Qiao CF, Qin N, Qin XS, Qin ZH, Qiu JF, Qu SQ, Rashid KH, Redmer CF, Richter M, Ripka M, Rivetti A, Rolo M, Rong G, Rosner C, Rump M, Sarantsev A, Savrié M, Schoenning K, Shan W, Shan XY, Shao M, Shen CP, Shen PX, Shen XY, Sheng HY, Shi X, Song JJ, Song XY, Sosio S, Sowa C, Spataro S, Sui FF, Sun GX, Sun JF, Sun L, Sun SS, Sun XH, Sun YJ, Sun YK, Sun YZ, Sun ZJ, Sun ZT, Tan YT, Tang CJ, Tang GY, Tang X, Tiemens M, Tsednee B, Uman I, Wang B, Wang BL, Wang CW, Wang D, Wang DY, Wang HH, Wang K, Wang LL, Wang LS, Wang M, Wang M, Wang P, Wang PL, Wang WP, Wang XF, Wang Y, Wang YF, Wang Z, Wang ZG, Wang ZY, Wang Z, Weber T, Wei DH, Weidenkaff P, Wen SP, Wiedner U, Wolke M, Wu LH, Wu LJ, Wu Z, Xia L, Xia Y, Xiao YJ, Xiao ZJ, Xie YG, Xie YH, Xiong XA, Xiu QL, Xu GF, Xu JJ, Xu L, Xu QJ, Xu XP, Yan F, Yan L, Yan WB, Yan WC, Yan YH, Yang HJ, Yang HX, Yang L, Yang RX, Yang SL, Yang YH, Yang YX, Yang Y, Yang ZQ, Ye M, Ye MH, Yin JH, You ZY, Yu BX, Yu CX, Yu JS, Yuan CZ, Yuan Y, Yuncu A, Zafar AA, Zeng Y, Zhang BX, Zhang BY, Zhang CC, Zhang DH, Zhang HH, Zhang HY, Zhang J, Zhang JL, Zhang JQ, Zhang JW, Zhang JY, Zhang JZ, Zhang K, Zhang L, Zhang SF, Zhang TJ, Zhang XY, Zhang Y, Zhang YH, Zhang YT, Zhang Y, Zhang Y, Zhang Y, Zhang ZH, Zhang ZP, Zhang ZY, Zhao G, Zhao JW, Zhao JY, Zhao JZ, Zhao L, Zhao L, Zhao MG, Zhao Q, Zhao SJ, Zhao TC, Zhao YB, Zhao ZG, Zhemchugov A, Zheng B, Zheng JP, Zheng YH, Zhong B, Zhou L, Zhou Q, Zhou X, Zhou XK, Zhou XR, Zhou X, Zhou X, Zhu AN, Zhu J, Zhu J, Zhu K, Zhu KJ, Zhu SH, Zhu XL, Zhu YC, Zhu YS, Zhu ZA, Zhuang J, Zou BS, Zou JH; BESIII Collaboration.

Phys Rev Lett. 2018 Aug 24;121(8):081802. doi: 10.1103/PhysRevLett.121.081802.


Automatic Anatomy Recognition using Neural Network Learning of Object Relationships via Virtual Landmarks.

Yan F, Udupa JK, Tong Y, Xu G, Odhner D, Torigian DA.

Proc SPIE Int Soc Opt Eng. 2018 Feb;10574. pii: 105742O. doi: 10.1117/12.2293700. Epub 2018 Mar 2.


Thoracic lymph node station recognition on CT images based on automatic anatomy recognition with an optimal parent strategy.

Xu G, Udupa JK, Tong Y, Cao H, Odhner D, Torigian DA, Wu X.

Proc SPIE Int Soc Opt Eng. 2018 Feb;10574. pii: 105742F. doi: 10.1117/12.2293258. Epub 2018 Mar 2.


Design, Synthesis, and Application of Highly Reducing Organic Visible-Light Photocatalysts.

Liu D, Jiao MJ, Feng ZT, Wang XZ, Xu GQ, Xu PF.

Org Lett. 2018 Sep 21;20(18):5700-5704. doi: 10.1021/acs.orglett.8b02420. Epub 2018 Sep 6.


Time-restricted feeding causes irreversible metabolic disorders and gut microbiota shift in pediatric mice.

Hu D, Mao Y, Xu G, Liao W, Ren J, Yang H, Yang J, Sun L, Chen H, Wang W, Wang Y, Sang X, Lu X, Zhang H, Zhong S.

Pediatr Res. 2018 Aug 28. doi: 10.1038/s41390-018-0156-z. [Epub ahead of print]


[Effects of Straw and Biochar Addition on Soil Carbon Balance and Ecological Benefits in a Rape-maize Rotation Planting System].

Li J, Tian D, Huang R, Xu GX, Li JC, Gao M, Wang ZF.

Huan Jing Ke Xue. 2018 Sep 8;39(9):4338-4347. doi: 10.13227/j.hjkx.201712051. Chinese.


Allelopathic Effects of Three Sweet Potato Cultivars (<I>Ipomoea batatas</I>) on the Invasive Plant <I> Mikania micrantha</I>.

Shen S, Xu G, Li D, Clements DR, Jin G, Liu S, Yang Y, Chen A, Zhang F, Hisashi KN.

Pak J Biol Sci. 2018;21(1):8-15. doi: 10.3923/pjbs.2018.8.15.


A novel combination of quick response code and microfluidic paper-based analytical devices for rapid and quantitative detection.

Wang T, Xu G, Wu W, Wang X, Chen X, Zhou S, You F.

Biomed Microdevices. 2018 Sep 5;20(3):79. doi: 10.1007/s10544-018-0325-1.


Combined antitumor effects of P-5m octapeptide and 5-fluorouracil on a murine model of H22 hepatoma ascites.

Han X, An L, Yan D, Hiroshi M, Ding W, Zhang M, Xu G, Sun Y, Yuan G, Wang M, Zhao N, Sun J, Zhu X, Du P.

Exp Ther Med. 2018 Sep;16(3):1586-1592. doi: 10.3892/etm.2018.6422. Epub 2018 Jul 6.


[Effects of microbial fertilizer on soil improvement and fruit quality of kiwifruit in old orchard.]

Ku YL, Xu GY, Zhao H, Dong TW, Cao CL.

Ying Yong Sheng Tai Xue Bao. 2018 Aug;29(8):2532-2540. doi: 10.13287/j.1001-9332.201808.025. Chinese.


Epidemiology and Serum Metabolic Characteristics of Acute Myocardial Infarction Patients in Chest Pain Centers.

Deng D, Liu L, Xu G, Gan J, Shen Y, Shi Y, Zhu R, Lin Y.

Iran J Public Health. 2018 Jul;47(7):1017-1029.


Prevalence of diagnosed type 1 and type 2 diabetes among US adults in 2016 and 2017: population based study.

Xu G, Liu B, Sun Y, Du Y, Snetselaar LG, Hu FB, Bao W.

BMJ. 2018 Sep 4;362:k1497. doi: 10.1136/bmj.k1497.


Effects of ionic strength on physicochemical properties and toxicity of silver nanoparticles.

Yang Y, Xu S, Xu G, Liu R, Xu A, Chen S, Wu L.

Sci Total Environ. 2018 Aug 5;647:1088-1096. doi: 10.1016/j.scitotenv.2018.08.064. [Epub ahead of print]


miR-145 protects the function of neuronal stem cells through targeting MAPK pathway in the treatment of cerebral ischemic stroke rat.

Xue WS, Wang N, Wang NY, Ying YF, Xu GH.

Brain Res Bull. 2018 Sep 1. pii: S0361-9230(18)30365-4. doi: 10.1016/j.brainresbull.2018.08.023. [Epub ahead of print]


Prognostic value of differentiation status in gastric cancer.

Feng F, Liu J, Wang F, Zheng G, Wang Q, Liu S, Xu G, Guo M, Lian X, Zhang H.

BMC Cancer. 2018 Sep 3;18(1):865. doi: 10.1186/s12885-018-4780-0.


Modifying Baculovirus Expression Vectors to Produce Secreted Plant Proteins in Insect Cells.

Chakraborty S, Trihemasava K, Xu G.

J Vis Exp. 2018 Aug 20;(138). doi: 10.3791/58283.


Morpholinyl dendrimer phthalocyanine: synthesis, photophysical properties and photoinduced intramolecular electron transfer.

Guo Q, Chen L, Pan S, Ma D, Liu X, Chen X, Xu G, Yang H, Peng Y.

Dalton Trans. 2018 Sep 3. doi: 10.1039/c8dt02275e. [Epub ahead of print]


Phylogenetic analysis of canine distemper viruses isolated from vaccinated dogs in Wuhan.

Li W, Cai C, Xue M, Xu G, Wang X, Zhang A, Han L.

J Vet Med Sci. 2018 Aug 31. doi: 10.1292/jvms.18-0116. [Epub ahead of print]


MicroRNA-9 Enhanced Cisplatin Sensitivity in Nonsmall Cell Lung Cancer Cells by Regulating Eukaryotic Translation Initiation Factor 5A2.

Pan Q, Sun L, Zheng D, Li N, Shi H, Song J, Shao G, Xu G.

Biomed Res Int. 2018 Aug 5;2018:1769040. doi: 10.1155/2018/1769040. eCollection 2018.


[Prognostic Value of Neutrophil-to-lymphocyte Ratio in Patients 
with Lung Adenocarcinoma Treated with Radical Dissection].

Wang G, Xiong R, Wu H, Xu G, Li C, Sun X, Xie M.

Zhongguo Fei Ai Za Zhi. 2018 Aug 20;21(8):588-593. doi: 10.3779/j.issn.1009-3419.2018.08.04. Chinese.


Projections for temperature-related years of life lost from cardiovascular diseases in the elderly in a Chinese city with typical subtropical climate.

Huang J, Li G, Liu Y, Huang J, Xu G, Qian X, Cen Z, Pan X, Xu A, Guo X, He T.

Environ Res. 2018 Aug 20;167:614-621. doi: 10.1016/j.envres.2018.08.024. [Epub ahead of print]


Cobalt nanoparticles embedded nitrogen-doped porous graphitized carbon composites with enhanced microwave absorption performance.

Quan B, Xu G, Gu W, Sheng J, Ji G.

J Colloid Interface Sci. 2018 Aug 25;533:297-303. doi: 10.1016/j.jcis.2018.08.083. [Epub ahead of print]


A novel scoring system for prediction of prostate cancer based on shear wave elastography and clinical parameters.

Su R, Xu G, Xiang L, Ding S, Wu R.

Urology. 2018 Aug 29. pii: S0090-4295(18)30910-5. doi: 10.1016/j.urology.2018.08.026. [Epub ahead of print]


Enantioselective Dechlorination of Polychlorinated Biphenyls in Dehalococcoides mccartyi CG1.

Yu L, Lu Q, Qiu L, Xu G, Zeng Y, Luo X, Wang S, Mai B.

Appl Environ Microbiol. 2018 Aug 31. pii: AEM.01300-18. doi: 10.1128/AEM.01300-18. [Epub ahead of print]


Renal immature teratoma in a male adult: A case report and literature review.

Zhang XL, Xu G, Li JL, Pan SH, Yan JJ.

Medicine (Baltimore). 2018 Aug;97(35):e12143. doi: 10.1097/MD.0000000000012143. Review.

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