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Automated Platform for Long-Term Culture and High-Content Phenotyping of Single C. elegans Worms.

Atakan HB, Xiang R, Cornaglia M, Mouchiroud L, Katsyuba E, Auwerx J, Gijs MAM.

Sci Rep. 2019 Oct 4;9(1):14340. doi: 10.1038/s41598-019-50920-8.


Break-induced replication plays a prominent role in long-range repeat-mediated deletion.

Hu Q, Lu H, Wang H, Li S, Truong L, Li J, Liu S, Xiang R, Wu X.

EMBO J. 2019 Oct 1:e101751. doi: 10.15252/embj.2019101751. [Epub ahead of print]


Quantifying the contribution of sequence variants with regulatory and evolutionary significance to 34 bovine complex traits.

Xiang R, Berg IVD, MacLeod IM, Hayes BJ, Prowse-Wilkins CP, Wang M, Bolormaa S, Liu Z, Rochfort SJ, Reich CM, Mason BA, Vander Jagt CJ, Daetwyler HD, Lund MS, Chamberlain AJ, Goddard ME.

Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19398-19408. doi: 10.1073/pnas.1904159116. Epub 2019 Sep 9.


Oxidised Low-Density Lipoprotein and Its Receptor-Mediated Endothelial Dysfunction Are Associated with Coronary Artery Lesions in Kawasaki Disease.

He YE, Qiu HX, Wu RZ, Rong X, Xu HT, Xiang RL, Chu MP.

J Cardiovasc Transl Res. 2019 Aug 19. doi: 10.1007/s12265-019-09908-y. [Epub ahead of print]


A novel mutation (c.1010G>T; p.R337L) in TP63 as a cause of split-hand/foot malformation with hypodontia.

Jin JY, Zeng L, Li K, He JQ, Pang X, Huang H, Xiang R, Tang JY.

J Gene Med. 2019 Oct;21(10):e3122. doi: 10.1002/jgm.3122. Epub 2019 Aug 30.


Novel dual inhibitors targeting CDK4 and VEGFR2 synergistically suppressed cancer progression and angiogenesis.

Huang Z, Zhao B, Qin Z, Li Y, Wang T, Zhou W, Zheng J, Yang S, Shi Y, Fan Y, Xiang R.

Eur J Med Chem. 2019 Jul 28;181:111541. doi: 10.1016/j.ejmech.2019.07.044. [Epub ahead of print]


Novel cyclin-dependent kinase 9 (CDK9) inhibitor with suppression of cancer stemness activity against non-small-cell lung cancer.

Wang X, Yu C, Wang C, Ma Y, Wang T, Li Y, Huang Z, Zhou M, Sun P, Zheng J, Yang S, Fan Y, Xiang R.

Eur J Med Chem. 2019 Jul 25;181:111535. doi: 10.1016/j.ejmech.2019.07.038. [Epub ahead of print]


Pseudoginsenoside-F11 Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Suppressing Neutrophil Infiltration and Accelerating Neutrophil Clearance.

Wang P, Hou Y, Zhang W, Zhang H, Che X, Gao Y, Liu Y, Yang D, Wang J, Xiang R, Zhao M, Yang J.

Inflammation. 2019 Oct;42(5):1857-1868. doi: 10.1007/s10753-019-01047-5.


Prevalence and Population Genetics Analysis of Enterocytozoon bieneusi in Dairy Cattle in China.

Wang HY, Qi M, Sun MF, Li DF, Wang RJ, Zhang SM, Zhao JF, Li JQ, Cui ZH, Chen YC, Jian FC, Xiang RP, Ning CS, Zhang LX.

Front Microbiol. 2019 Jun 25;10:1399. doi: 10.3389/fmicb.2019.01399. eCollection 2019.


Hypoxia-induced long non-coding RNA DARS-AS1 regulates RBM39 stability to promote myeloma malignancy.

Tong J, Xu X, Zhang Z, Ma C, Xiang R, Liu J, Xu W, Wu C, Li J, Zhan F, Wu Y, Yan H.

Haematologica. 2019 Jul 9. pii: haematol.2019.218289. doi: 10.3324/haematol.2019.218289. [Epub ahead of print]


Simultaneous and visual detection of infectious bronchitis virus and Newcastle disease virus by multiple LAMP and lateral flow dipstick.

Wu X, Song Z, Zhai X, Zuo L, Mei X, Xiang R, Kang Z, Zhou L, Wang H.

Poult Sci. 2019 Nov 1;98(11):5401-5411. doi: 10.3382/ps/pez372.


CD137 promotes bone metastasis of breast cancer by enhancing the migration and osteoclast differentiation of monocytes/macrophages.

Jiang P, Gao W, Ma T, Wang R, Piao Y, Dong X, Wang P, Zhang X, Liu Y, Su W, Xiang R, Zhang J, Li N.

Theranostics. 2019 May 9;9(10):2950-2966. doi: 10.7150/thno.29617. eCollection 2019.


Enhancement of Histone Deacetylase Inhibitor Sensitivity in Combination with Cyclin-Dependent Kinase Inhibition for the Treatment of Oral Squamous Cell Carcinoma.

Zhao B, Huang Z, Qin Z, Li Y, Wang T, Wang L, Zhou W, Yu C, Wang X, Yang S, Fan Y, Xiang R.

Cell Physiol Biochem. 2019;53(1):141-156. doi: 10.33594/000000126.


Atomic-scale structural identification and evolution of Co-W-C ternary SWCNT catalytic nanoparticles: High-resolution STEM imaging on SiO2.

An H, Kumamoto A, Xiang R, Inoue T, Otsuka K, Chiashi S, Bichara C, Loiseau A, Li Y, Ikuhara Y, Maruyama S.

Sci Adv. 2019 May 24;5(5):eaat9459. doi: 10.1126/sciadv.aat9459. eCollection 2019 May.


The incidence and relative risk of adverse events in patients treated with bisphosphonate therapy for breast cancer: a systematic review and meta-analysis.

Yang YL, Xiang ZJ, Yang JH, Wang WJ, Xiang RL.

Ther Adv Med Oncol. 2019 Jun 9;11:1758835919855235. doi: 10.1177/1758835919855235. eCollection 2019.


Telomere Maintenance-Associated PML Is a Potential Specific Therapeutic Target of Human Colorectal Cancer.

Gong P, Wang H, Zhang J, Fu Y, Zhu Z, Wang J, Yin Y, Wang H, Zhou Z, Yang J, Liu L, Gou M, Zeng M, Yuan J, Wang F, Pan X, Xiang R, Weissman SM, Qi F, Liu L.

Transl Oncol. 2019 Sep;12(9):1164-1176. doi: 10.1016/j.tranon.2019.05.010. Epub 2019 Jun 15.


Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling.

Zhao Y, Xiang R, Peng X, Dong Q, Li D, Yu G, Xiao L, Qin S, Huang W.

Respir Res. 2019 Jun 14;20(1):121. doi: 10.1186/s12931-019-1090-2.


Type 2 diabetes-induced hyposalivation of the submandibular gland through PINK1/Parkin-mediated mitophagy.

Xiang RL, Huang Y, Zhang Y, Cong X, Zhang ZJ, Wu LL, Yu GY.

J Cell Physiol. 2020 Jan;235(1):232-244. doi: 10.1002/jcp.28962. Epub 2019 Jun 12.


Structural elucidation of a dimeric impurity in the process development of ceftolozane using LC/HRMS and 2D-NMR.

Liao J, Sheng H, Saurí J, Xiang R, Martin G.

J Pharm Biomed Anal. 2019 Sep 10;174:242-247. doi: 10.1016/j.jpba.2019.05.057. Epub 2019 May 26.


The use of mid-infrared spectra to map genes affecting milk composition.

Benedet A, Ho PN, Xiang R, Bolormaa S, De Marchi M, Goddard ME, Pryce JE.

J Dairy Sci. 2019 Aug;102(8):7189-7203. doi: 10.3168/jds.2018-15890. Epub 2019 Jun 6.


Exosomal miR-451a Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Targeting LPIN1.

Zhao S, Li J, Zhang G, Wang Q, Wu C, Zhang Q, Wang H, Sun P, Xiang R, Yang S.

Cell Physiol Biochem. 2019;53(1):19-35. doi: 10.33594/000000118.


ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures.

Li S, Lu H, Wang Z, Hu Q, Wang H, Xiang R, Chiba T, Wu X.

iScience. 2019 Jun 28;16:63-78. doi: 10.1016/j.isci.2019.05.017. Epub 2019 May 16.


Asparaginyl endopeptidase induces endothelial permeability and tumor metastasis via downregulating zonula occludens protein ZO-1.

Kang L, Shen L, Lu L, Wang D, Zhao Y, Chen C, Du L, Gong J, Zhang Y, Mi X, Xiang R, Zhang M, Tan X.

Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2267-2275. doi: 10.1016/j.bbadis.2019.05.003. Epub 2019 May 13.


Natural killer cells kill Burkholderia cepacia complex via a contact-dependent and cytolytic mechanism.

Li SS, Saleh M, Xiang RF, Ogbomo H, Stack D, Huston SH, Mody CH.

Int Immunol. 2019 May 21;31(6):385-396. doi: 10.1093/intimm/dxz016.


Endoscopic robot-assisted simple enucleation of renal tumours: Impact of learning curve and tumour complexity on trifecta outcomes.

Lu Z, Zhou J, Yang C, Zhang L, Tai S, Xiang R, Liang C.

Int J Med Robot. 2019 Aug;15(4):e2000. doi: 10.1002/rcs.2000. Epub 2019 May 30.


Expression of CLDN6 in tissues of gastric cancer patients: Association with clinical pathology and prognosis.

Gao F, Li M, Xiang R, Zhou X, Zhu L, Zhai Y.

Oncol Lett. 2019 May;17(5):4621-4625. doi: 10.3892/ol.2019.10129. Epub 2019 Mar 8.


Comparative efficacy and safety of local and peripheral venous thrombolytic therapy with urokinase for thrombosed hemodialysis arteriovenous fistulas.

Wan Z, Xiang R, Wang H, Zhong Q, Tu B.

Exp Ther Med. 2019 May;17(5):4279-4284. doi: 10.3892/etm.2019.7415. Epub 2019 Mar 20.


TLR4 increases the stemness and is highly expressed in relapsed human hepatocellular carcinoma.

Zhou S, Du R, Wang Z, Shen W, Gao R, Jiang S, Fang Y, Shi Y, Chang A, Liu L, Liu C, Li N, Xiang R.

Cancer Med. 2019 May;8(5):2325-2337. doi: 10.1002/cam4.2070. Epub 2019 Apr 8.


Tuning Interfacial Structures for Better Catalysis of Water Electrolysis.

Xiang R, Peng L, Wei Z.

Chemistry. 2019 Jul 25;25(42):9799-9815. doi: 10.1002/chem.201901168. Epub 2019 May 30. Review.


Efficacy and safety of spironolactone in the heart failure with mid-range ejection fraction and heart failure with preserved ejection fraction: A meta-analysis of randomized clinical trials.

Xiang Y, Shi W, Li Z, Yang Y, Wang SY, Xiang R, Feng P, Wen L, Huang W.

Medicine (Baltimore). 2019 Mar;98(13):e14967. doi: 10.1097/MD.0000000000014967.


Engineered Cell-Assisted Photoactive Nanoparticle Delivery for Image-Guided Synergistic Photodynamic/Photothermal Therapy of Cancer.

Wang P, Wu W, Gao R, Zhu H, Wang J, Du R, Li X, Zhang C, Cao S, Xiang R.

ACS Appl Mater Interfaces. 2019 Apr 17;11(15):13935-13944. doi: 10.1021/acsami.9b00022. Epub 2019 Apr 4.


Complete Genome Sequence of Parainfluenza Virus 5 (PIV5) from a Sunda Pangolin (Manis javanica) in China.

Wang X, Chen W, Xiang R, Li L, Chen J, Zhong R, Xiang H, Chen J.

J Wildl Dis. 2019 Oct;55(4):947-950. Epub 2019 Mar 21.


Construction and Immunogenicity of Novel Chimeric Virus-Like Particles Bearing Antigens of Infectious Bronchitis Virus and Newcastle Disease Virus.

Wu X, Zhai X, Lai Y, Zuo L, Zhang Y, Mei X, Xiang R, Kang Z, Zhou L, Wang H.

Viruses. 2019 Mar 13;11(3). pii: E254. doi: 10.3390/v11030254.


Uniportal video-assisted thoracoscopic surgery: Sichuan Cancer Hospital experience.

Zhang H, Xiang R, He J, Zhu J.

J Thorac Dis. 2019 Jan;11(1):273-275. doi: 10.21037/jtd.2018.12.76. No abstract available.


Comparative efficacy and safety of multiple antiplatelet therapies for secondary prevention of ischemic stroke or transient ischemic attack: A network meta-analysis.

Xiang RW, Han RB, Yang JY, Zhao MY, Zhao QC, Chen HS, Zhao FQ, Sun ZY, Zhao T, Song TY.

J Neurol Sci. 2019 Apr 15;399:199-206. doi: 10.1016/j.jns.2019.02.037. Epub 2019 Feb 27.


Microbial killing by NK cells.

Mody CH, Ogbomo H, Xiang RF, Kyei SK, Feehan D, Islam A, Li SS.

J Leukoc Biol. 2019 Jun;105(6):1285-1296. doi: 10.1002/JLB.MR0718-298R. Epub 2019 Mar 1. Review.


Inert V2O3 oxide promotes the electrocatalytic activity of Ni metal for alkaline hydrogen evolution.

Ji D, Peng L, Shen J, Deng M, Mao Z, Tan L, Wang M, Xiang R, Wang J, Shah SSA.

Chem Commun (Camb). 2019 Mar 12;55(22):3290-3293. doi: 10.1039/c8cc10128k.


Recent Progress on Liquid Biopsy Analysis using Surface-Enhanced Raman Spectroscopy.

Zhang Y, Mi X, Tan X, Xiang R.

Theranostics. 2019 Jan 1;9(2):491-525. doi: 10.7150/thno.29875. eCollection 2019. Review.


Immunostimulatory Activities of CpG-Oligodeoxynucleotides in Teleosts: Toll-Like Receptors 9 and 21.

Lai CY, Yu GY, Luo Y, Xiang R, Chuang TH.

Front Immunol. 2019 Feb 8;10:179. doi: 10.3389/fimmu.2019.00179. eCollection 2019. Review.


Protection of miR-19b in hypoxia/reoxygenation-induced injury by targeting PTEN.

Liu WG, Han LL, Xiang R.

J Cell Physiol. 2019 Feb 14. doi: 10.1002/jcp.28286. [Epub ahead of print]


Targeting LIN28B reprograms tumor glucose metabolism and acidic microenvironment to suppress cancer stemness and metastasis.

Chen C, Bai L, Cao F, Wang S, He H, Song M, Chen H, Liu Y, Guo J, Si Q, Pan Y, Zhu R, Chuang TH, Xiang R, Luo Y.

Oncogene. 2019 Jun;38(23):4527-4539. doi: 10.1038/s41388-019-0735-4. Epub 2019 Feb 11.


Two Chinese Xia-Gibbs syndrome patients with partial growth hormone deficiency.

Cheng X, Tang F, Hu X, Li H, Li M, Fu Y, Yan L, Li Z, Gou P, Su N, Gong C, He W, Xiang R, Bu D, Shen Y.

Mol Genet Genomic Med. 2019 Apr;7(4):e00596. doi: 10.1002/mgg3.596. Epub 2019 Feb 6.


Whole exome sequencing identified a novel mutation (p.Ala1884Pro) of β-spectrin in a Chinese family with hereditary spherocytosis.

Fan LL, Liu JS, Huang H, Du R, Xiang R.

J Gene Med. 2019 Feb;21(2-3):e3073. doi: 10.1002/jgm.3073. Epub 2019 Feb 11.


DNA polymerase θ (POLQ) is important for repair of DNA double-strand breaks caused by fork collapse.

Wang Z, Song Y, Li S, Kurian S, Xiang R, Chiba T, Wu X.

J Biol Chem. 2019 Mar 15;294(11):3909-3919. doi: 10.1074/jbc.RA118.005188. Epub 2019 Jan 17.


The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression.

Xiong Y, Li L, Zhang L, Cui Y, Wu C, Li H, Chen K, Yang Q, Xiang R, Hu Y, Huang S, Wei Y, Yang S.

Cell Death Differ. 2019 Oct;26(10):1929-1941. doi: 10.1038/s41418-018-0262-9. Epub 2019 Jan 15.


Whole-Exome Sequencing Identifies a Novel Mutation (p.L320R) of Alpha-Actinin 2 in a Chinese Family with Dilated Cardiomyopathy and Ventricular Tachycardia.

Fan LL, Huang H, Jin JY, Li JJ, Chen YQ, Xiang R.

Cytogenet Genome Res. 2019;157(3):148-152. doi: 10.1159/000496077. Epub 2019 Jan 11.


The Prevalence of Colistin Resistant Strains and Antibiotic Resistance Gene Profiles in Funan River, China.

Tuo H, Yang Y, Tao X, Liu D, Li Y, Xie X, Li P, Gu J, Kong L, Xiang R, Lei C, Wang H, Zhang A.

Front Microbiol. 2018 Dec 18;9:3094. doi: 10.3389/fmicb.2018.03094. eCollection 2018.


Semaphorin 3A inhibits allergic inflammation by regulating immune responses in a mouse model of allergic rhinitis.

Xiang R, Xu Y, Zhang W, Kong YG, Tan L, Chen SM, Deng YQ, Tao ZZ.

Int Forum Allergy Rhinol. 2019 May;9(5):528-537. doi: 10.1002/alr.22274. Epub 2018 Dec 31.


miR-100 maintains phenotype of tumor-associated macrophages by targeting mTOR to promote tumor metastasis via Stat5a/IL-1ra pathway in mouse breast cancer.

Wang W, Liu Y, Guo J, He H, Mi X, Chen C, Xie J, Wang S, Wu P, Cao F, Bai L, Si Q, Xiang R, Luo Y.

Oncogenesis. 2018 Dec 19;7(12):97. doi: 10.1038/s41389-018-0106-y.


Exome sequencing identifies a novel nonsense mutation of Ring Finger Protein 207 in a Chinese family with Long QT syndrome and syncope.

Fan LL, Chen YQ, Huang H, Yuan ZZ, Jin JY, Hu M, Xiang R.

J Hum Genet. 2019 Mar;64(3):233-238. doi: 10.1038/s10038-018-0549-1. Epub 2018 Dec 12.


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