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Items: 1 to 50 of 74

1.

Muscle aches and pains: do I have leukemia?

Deschner M, Phua C, Saini L, Xenocostas A, Deotare U.

Int J Hematol. 2019 Oct 14. doi: 10.1007/s12185-019-02746-3. [Epub ahead of print]

PMID:
31612308
2.

Implementation of an NGS-based sequencing and gene fusion panel for clinical screening of patients with suspected hematologic malignancies.

Levy MA, Santos S, Kerkhof J, Stuart A, Aref-Eshghi E, Guo F, Hedley B, Wong H, Rauh M, Feilotter H, Berardi P, Semenuk L, Yang P, Knoll J, Ainsworth P, McLachlin CM, Chin-Yee I, Kovacs M, Deotare U, Lazo-Langner A, Hsia C, Keeney M, Xenocostas A, Howlett C, Lin H, Sadikovic B.

Eur J Haematol. 2019 Sep;103(3):178-189. doi: 10.1111/ejh.13272. Epub 2019 Jul 30.

PMID:
31177553
3.

Human Multipotent Stromal Cell Secreted Effectors Accelerate Islet Regeneration.

Kuljanin M, Elgamal RM, Bell GI, Xenocostas A, Lajoie GA, Hess DA.

Stem Cells. 2019 Apr;37(4):516-528. doi: 10.1002/stem.2976. Epub 2019 Jan 30.

PMID:
30674070
4.

Quantitative Proteomics Evaluation of Human Multipotent Stromal Cell for β Cell Regeneration.

Kuljanin M, Elgamal RM, Bell GI, Xenocostas D, Xenocostas A, Hess DA, Lajoie GA.

Cell Rep. 2018 Nov 27;25(9):2524-2536.e4. doi: 10.1016/j.celrep.2018.10.107.

5.

Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence.

Boyd AL, Aslostovar L, Reid J, Ye W, Tanasijevic B, Porras DP, Shapovalova Z, Almakadi M, Foley R, Leber B, Xenocostas A, Bhatia M.

Cancer Cell. 2018 Sep 10;34(3):483-498.e5. doi: 10.1016/j.ccell.2018.08.007.

6.

A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia.

Aslostovar L, Boyd AL, Almakadi M, Collins TJ, Leong DP, Tirona RG, Kim RB, Julian JA, Xenocostas A, Leber B, Levine MN, Foley R, Bhatia M.

Blood Adv. 2018 Aug 14;2(15):1935-1945. doi: 10.1182/bloodadvances.2018015677.

7.

Adherence to, and outcomes of, a galactomannan screening protocol in high-risk hematology patients.

Harricharan S, Biederman K, Bombassaro AM, Lazo-Langner A, Elsayed S, Fulford A, Delport JA, Xenocostas A.

Curr Oncol. 2018 Apr;25(2):e139-e145. doi: 10.3747/co.25.3848. Epub 2018 Apr 30.

8.

Increased Susceptibility for Atrial and Ventricular Cardiac Arrhythmias in Mice Treated With a Single High Dose of Ibrutinib.

Tuomi JM, Xenocostas A, Jones DL.

Can J Cardiol. 2018 Mar;34(3):337-341. doi: 10.1016/j.cjca.2017.12.001. Epub 2017 Dec 7.

PMID:
29475534
9.

Quality of life trajectories during the first year following hematopoietic cell transplantation: an inception cohort study.

Devins GM, Mah K, Messner HA, Xenocostas A, Gauvin L, Lipton JH.

Support Care Cancer. 2018 Jul;26(7):2379-2386. doi: 10.1007/s00520-018-4059-7. Epub 2018 Feb 8.

PMID:
29423678
10.

Sex-specific analysis post-liver transplantation in hemochromatosis with aplastic anemia and hepatocellular carcinoma.

Adams P, Howlett C, Xenocostas A, Chakrabarti S.

Hepatol Commun. 2017 Nov 11;2(1):13-15. doi: 10.1002/hep4.1122. eCollection 2018 Jan.

11.

Erythropoiesis-stimulating agents in elderly patients with anemia: response and cardiovascular outcomes.

Gowanlock Z, Sriram S, Martin A, Xenocostas A, Lazo-Langner A.

Blood Adv. 2017 Aug 17;1(19):1538-1545. doi: 10.1182/bloodadvances.2017007559. eCollection 2017 Aug 22.

12.

Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche.

Boyd AL, Reid JC, Salci KR, Aslostovar L, Benoit YD, Shapovalova Z, Nakanishi M, Porras DP, Almakadi M, Campbell CJV, Jackson MF, Ross CA, Foley R, Leber B, Allan DS, Sabloff M, Xenocostas A, Collins TJ, Bhatia M.

Nat Cell Biol. 2017 Nov;19(11):1336-1347. doi: 10.1038/ncb3625. Epub 2017 Oct 16.

PMID:
29035359
13.

Sam68 Allows Selective Targeting of Human Cancer Stem Cells.

Benoit YD, Mitchell RR, Risueño RM, Orlando L, Tanasijevic B, Boyd AL, Aslostovar L, Salci KR, Shapovalova Z, Russell J, Eguchi M, Golubeva D, Graham M, Xenocostas A, Trus MR, Foley R, Leber B, Collins TJ, Bhatia M.

Cell Chem Biol. 2017 Jul 20;24(7):833-844.e9. doi: 10.1016/j.chembiol.2017.05.026. Epub 2017 Jun 22.

14.

C-peptide attenuates acute lung inflammation in a murine model of hemorrhagic shock and resuscitation by reducing gut injury.

Kao RLC, Xu X, Xenocostas A, Parry N, Mele T, Martin CM, Rui T.

J Trauma Acute Care Surg. 2017 Aug;83(2):256-262. doi: 10.1097/TA.0000000000001539.

PMID:
28452895
15.

Plerixafor for autologous stem-cell mobilization and transplantation for patients in Ontario.

Kouroukis CT, Varela NP, Bredeson C, Kuruvilla J, Xenocostas A.

Curr Oncol. 2016 Aug;23(4):e409-30. doi: 10.3747/co.23.3137. Epub 2016 Aug 12.

16.

Erythropoietin Levels in Elderly Patients with Anemia of Unknown Etiology.

Gowanlock Z, Sriram S, Martin A, Xenocostas A, Lazo-Langner A.

PLoS One. 2016 Jun 16;11(6):e0157279. doi: 10.1371/journal.pone.0157279. eCollection 2016.

17.

Randomized double-blind safety comparison of intravenous iron dextran versus iron sucrose in an adult non-hemodialysis outpatient population: A feasibility study.

Louzada ML, Hsia CC, Al-Ani F, Ralley F, Xenocostas A, Martin J, Connelly SE, Chin-Yee IH, Minuk L, Lazo-Langner A.

BMC Hematol. 2016 Mar 11;16:7. doi: 10.1186/s12878-016-0046-8. eCollection 2016.

18.

Erythropoietin in anemia of unknown etiology: A systematic review and meta-analysis.

Sriram S, Xenocostas A, Lazo-Langner A.

Hematology. 2016 May;21(4):234-40. doi: 10.1080/10245332.2015.1101972. Epub 2016 Jan 8. Review.

PMID:
26747131
19.

Improved Prediction of CD34+ Cell Yield before Peripheral Blood Hematopoietic Progenitor Cell Collection Using a Modified Target Value-Tailored Approach.

Sheppard D, Tay J, Palmer D, Xenocostas A, Doulaverakis C, Huebsch L, McDiarmid S, Tinmouth A, Mallick R, Martin L, Birch P, Hamelin L, Allan D, Bredeson C.

Biol Blood Marrow Transplant. 2016 Apr;22(4):763-767. doi: 10.1016/j.bbmt.2015.11.016. Epub 2015 Nov 28.

20.

Response to "Need to minimize bias when surveying patient attitudes to stopping cml treatment".

Sanford D, Kyle R, Lazo-Langner A, Xenocostas A, Chin-Yee I, Howson-Jan K, Hsia CC.

Curr Oncol. 2014 Dec;21(6):e803-4. doi: 10.3747/co.21.2200. No abstract available.

21.

Induction of acute lung inflammation in mice with hemorrhagic shock and resuscitation: role of HMGB1.

Kao RL, Xu X, Xenocostas A, Parry N, Mele T, Martin CM, Rui T.

J Inflamm (Lond). 2014 Oct 8;11(1):30. doi: 10.1186/s12950-014-0030-7. eCollection 2014.

22.

Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs.

Boyd AL, Campbell CJ, Hopkins CI, Fiebig-Comyn A, Russell J, Ulemek J, Foley R, Leber B, Xenocostas A, Collins TJ, Bhatia M.

J Exp Med. 2014 Sep 22;211(10):1925-35. doi: 10.1084/jem.20140131. Epub 2014 Sep 1.

23.

Favorable outcomes from allogeneic and autologous stem cell transplantation for patients with transformed nonfollicular indolent lymphoma.

Villa D, George A, Seymour JF, Toze CL, Crump M, Lee C, Buckstein R, Stewart DA, MacDonald D, Foley R, Xenocostas A, Sabloff M, Chua N, Couture F, Larouche JF, Cohen S, Savage KJ, Connors JM, Panzarella T, Carney DA, Dickinson M, Kuruvilla J.

Biol Blood Marrow Transplant. 2014 Nov;20(11):1813-8. doi: 10.1016/j.bbmt.2014.07.015. Epub 2014 Jul 18.

24.

Development of Myasthenia Gravis in a Patient with Chronic Myeloid Leukemia during Treatment with Nilotinib.

Sanford D, MacDonald M, Nicolle M, Xenocostas A.

Hematol Rep. 2014 Jun 19;6(2):5288. doi: 10.4081/hr.2014.5288. eCollection 2014 Apr 22.

25.

Patient preferences for stopping tyrosine kinase inhibitors in chronic myeloid leukemia.

Sanford D, Kyle R, Lazo-Langner A, Xenocostas A, Chin-Yee I, Howson-Jan K, Hsia C.

Curr Oncol. 2014 Apr;21(2):e241-9. doi: 10.3747/co.21.1736.

26.

Sunitinib malate in patients with intermediate-2 or high-risk myelodysplastic syndrome or chronic myelomonocytic leukemia.

Yee KW, Storring JM, Buckstein R, Wells RA, Xenocostas A, Kovacs MJ, Howson-Jan K, Wang ES, Battista K, Wang L, Oza AM, Ivy SP, Schuh AC.

Leuk Lymphoma. 2014 Nov;55(11):2669-71. doi: 10.3109/10428194.2014.900763. Epub 2014 Apr 22. No abstract available.

PMID:
24611649
27.

Regional localization within the bone marrow influences the functional capacity of human HSCs.

Guezguez B, Campbell CJ, Boyd AL, Karanu F, Casado FL, Di Cresce C, Collins TJ, Shapovalova Z, Xenocostas A, Bhatia M.

Cell Stem Cell. 2013 Aug 1;13(2):175-89. doi: 10.1016/j.stem.2013.06.015.

28.

Predictors of unsuccessful mobilization with granulocyte colony-stimulating factor alone in patients undergoing autologous hematopoietic stem cell transplantation.

Chow S, Lazo-Langner A, Ormond G, Howson-Jan K, Xenocostas A.

J Clin Apher. 2013 Aug;28(4):285-92. doi: 10.1002/jca.21252. Epub 2013 Feb 21.

PMID:
23426584
29.

Autologous and allogeneic stem-cell transplantation for transformed follicular lymphoma: a report of the Canadian blood and marrow transplant group.

Villa D, Crump M, Panzarella T, Savage KJ, Toze CL, Stewart DA, MacDonald DA, Buckstein R, Lee C, Alzahrani M, Rubinger M, Foley R, Xenocostas A, Sabloff M, Muccilli A, Chua N, Couture F, Larouche JF, Cohen S, Connors JM, Ambler K, Al-Tourah A, Ramadan KM, Kuruvilla J.

J Clin Oncol. 2013 Mar 20;31(9):1164-71. doi: 10.1200/JCO.2012.44.0693. Epub 2013 Feb 11.

PMID:
23401459
30.

Ustekinumab associated thrombotic thrombocytopenic purpura.

Huang SH, Xenocostas A, Moist LM, Crowther M, Moore JC, Clark WF.

Transfus Apher Sci. 2012 Oct;47(2):185-8. doi: 10.1016/j.transci.2012.06.024. Epub 2012 Aug 1.

PMID:
22858359
31.

Encapsulation and controlled release of recombinant human erythropoietin from chitosan-carrageenan nanoparticles.

Bulmer C, Margaritis A, Xenocostas A.

Curr Drug Deliv. 2012 Sep;9(5):527-37.

PMID:
22812393
32.

Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.

Sachlos E, Risueño RM, Laronde S, Shapovalova Z, Lee JH, Russell J, Malig M, McNicol JD, Fiebig-Comyn A, Graham M, Levadoux-Martin M, Lee JB, Giacomelli AO, Hassell JA, Fischer-Russell D, Trus MR, Foley R, Leber B, Xenocostas A, Brown ED, Collins TJ, Bhatia M.

Cell. 2012 Jun 8;149(6):1284-97. doi: 10.1016/j.cell.2012.03.049. Epub 2012 May 24.

33.

May-Hegglin anomaly.

Hsia CC, Xenocostas A.

Blood. 2012 Jan 12;119(2):328. No abstract available.

PMID:
22351964
34.

Combinatorial human progenitor cell transplantation optimizes islet regeneration through secretion of paracrine factors.

Bell GI, Meschino MT, Hughes-Large JM, Broughton HC, Xenocostas A, Hess DA.

Stem Cells Dev. 2012 Jul 20;21(11):1863-76. doi: 10.1089/scd.2011.0634. Epub 2012 Apr 16.

PMID:
22309189
35.

Polycythemia vera with pancytopenia and red cell fragmentation.

Hsia CC, Xenocostas A.

Blood. 2011 Nov 3;118(18):4769. No abstract available.

PMID:
22167863
36.

Erythropoietin improves skeletal muscle microcirculation through the activation of eNOS in a mouse sepsis model.

Kao RL, Martin CM, Xenocostas A, Huang W, Rui T.

J Trauma. 2011 Nov;71(5 Suppl 1):S462-7. doi: 10.1097/TA.0b013e318232e7a2.

PMID:
22072004
37.

Recombinant human erythropoietin improves gut barrier function in a hemorrhagic shock and resuscitation rat model.

Kao NR, Xenocostas A, Driman DK, Rui T, Huang W, Jiao X, Martin CM.

J Trauma. 2011 Nov;71(5 Suppl 1):S456-61. doi: 10.1097/TA.0b013e318232e782.

PMID:
22072003
38.

Posterior reversible encephalopathy syndrome in a patient with multiple myeloma treated with thalidomide.

Chow S, Cheung CS, Lee DH, Howson-Jan K, Xenocostas A.

Leuk Lymphoma. 2012 May;53(5):1003-5. doi: 10.3109/10428194.2011.638070. Epub 2011 Dec 6. No abstract available.

PMID:
22054288
39.

Transfusion of fresh but not old stored blood reduces infarct size and improves cardiac function after acute myocardial infarction in anemic rats*.

Hu H, Xenocostas A, Chin-Yee N, Lu X, Chin-Yee I, Feng Q.

Crit Care Med. 2012 Mar;40(3):740-6. doi: 10.1097/CCM.0b013e3182376e84.

PMID:
22001589
40.

Recombinant human erythropoietin in combination with chemotherapy increases breast cancer metastasis in preclinical mouse models.

Hedley BD, Chu JE, Ormond DG, Beausoleil MS, Boasie A, Allan AL, Xenocostas A.

Clin Cancer Res. 2011 Oct 1;17(19):6151-62. doi: 10.1158/1078-0432.CCR-10-3298. Epub 2011 Aug 19.

41.

The role of erythropoietin and erythropoiesis-stimulating agents in tumor progression.

Hedley BD, Allan AL, Xenocostas A.

Clin Cancer Res. 2011 Oct 15;17(20):6373-80. doi: 10.1158/1078-0432.CCR-10-2577. Epub 2011 Jul 12. Review.

42.

Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease.

Risueño RM, Campbell CJ, Dingwall S, Levadoux-Martin M, Leber B, Xenocostas A, Bhatia M.

Blood. 2011 Jun 30;117(26):7112-20. doi: 10.1182/blood-2011-01-329078. Epub 2011 May 11.

PMID:
21562049
43.

Transplanted human bone marrow progenitor subtypes stimulate endogenous islet regeneration and revascularization.

Bell GI, Broughton HC, Levac KD, Allan DA, Xenocostas A, Hess DA.

Stem Cells Dev. 2012 Jan;21(1):97-109. doi: 10.1089/scd.2010.0583. Epub 2011 Oct 21.

PMID:
21417581
44.

Erythropoietin encapsulation in chitosan nanoparticles and kinetics of drug release.

Bokharaei M, Margaritis A, Xenocostas A, Freeman DJ.

Curr Drug Deliv. 2011 Mar;8(2):164-71.

PMID:
21235481
45.

Erythropoietin is equally effective as fresh-blood transfusion at reducing infarct size in anemic rats.

Xenocostas A, Hu H, Chin-Yee N, Lu X, Chin-Yee I, Feng Q.

Crit Care Med. 2010 Nov;38(11):2215-21. doi: 10.1097/CCM.0b013e3181f17d6e. Erratum in: Crit Care Med. 2011 Jan;39(1):243.

PMID:
20693887
46.

The effect of erythropoietin on microcirculation perfusion and tissue bioenergetics of the small intestine in a hemorrhagic shock and resuscitation rat model.

Kao RL, Xenocostas A, Rui T, Huang W, Martin CM.

J Trauma. 2010 Jun;68(6):1342-8. doi: 10.1097/TA.0b013e3181d27dbe.

PMID:
20539178
47.

The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity.

Campbell CJ, Lee JB, Levadoux-Martin M, Wynder T, Xenocostas A, Leber B, Bhatia M.

Blood. 2010 Sep 2;116(9):1433-42. doi: 10.1182/blood-2009-12-258095. Epub 2010 Jun 4.

PMID:
20525924
48.

Molecular basis of cardioprotection by erythropoietin.

Burger D, Xenocostas A, Feng QP.

Curr Mol Pharmacol. 2009 Jan;2(1):56-69. Review.

PMID:
20021446
49.

Outcomes of reduced-intensity conditioning allo-SCT for Hodgkin's lymphoma: a national review by the Canadian Blood and Marrow Transplant Group.

Kuruvilla J, Pintilie M, Stewart D, Lachance S, Power M, Couture F, Xenocostas A, Voralia M, Couban S, Foley R.

Bone Marrow Transplant. 2010 Jul;45(7):1253-5. doi: 10.1038/bmt.2009.321. Epub 2009 Nov 16. No abstract available.

PMID:
19915625
50.

Effects of anemia and blood transfusion in acute myocardial infarction in rats.

Hu H, Xenocostas A, Chin-Yee I, Lu X, Feng Q.

Transfusion. 2010 Jan;50(1):243-51. doi: 10.1111/j.1537-2995.2009.02385.x. Epub 2009 Sep 22.

PMID:
19778337

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