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Items: 1 to 50 of 55

1.

US immigration order strikes against biotech.

Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci WE, McArthur JG, McCann CM, McCarthy SA, McDonough CG, Mendlein J, Miller L, Miralles D, Moch KI, More B, Myers AG, Narachi MA, Nashat A, Nelson W, Newell WJ, Olle B, Osborn JE, Owens JC, Pande A, Papadopoulos S, Parker HS, Parmar KM, Patterson MR, Paul SM, Perez R, Perry M, Pfeffer CG, Powell M, Pruzanski M, Purcell DJ, Rakhit A, Ramamoorthi K, Rastetter W, Rawcliffe AA, Reid LE, Renaud RC, Rhodes JP, Rieflin WJ, Robins C, Rocklage SM, Rosenblatt M, Rosin JG, Rutter WJ, Saha S, Samuels C, Sato VL, Scangos G, Scarlett JA, Schenkein D, Schreiber SL, Schwab A, Sekhri P, Shah R, Shenk T, Siegall CB, Simon NJ, Simonian N, Stein J, Su M, Szela MT, Taglietti M, Tandon N, Termeer H, Thornberry NA, Tolar M, Ulevitch R, Vaishnaw AK, VanLent A, Varsavsky M, Vlasuk GP, Vounatsos M, Waksal SG, Warma N, Watts RJ, Werber Y, Westphal C, Wierenga W, Williams DE, Williams LR, Xanthopoulos KG, Zohar D, Zweifach SS.

Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. No abstract available.

PMID:
28267733
2.

The art of the alliance.

Menzel GE, Xanthopoulos KG.

Nat Biotechnol. 2012 Apr 10;30(4):313-5. doi: 10.1038/nbt.2150. No abstract available.

PMID:
22491275
3.

Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.

Yamasaki H, Sada A, Iwata T, Niwa T, Tomizawa M, Xanthopoulos KG, Koike T, Shiojiri N.

Development. 2006 Nov;133(21):4233-43. Epub 2006 Oct 4.

4.

Induction of a therapeutic antitumor immunological response by intratumoral injection of genetically engineered Semliki Forest virus to produce interleukin-12.

Yamanaka R, Zullo SA, Tanaka R, Ramsey J, Blaese M, Xanthopoulos KG.

Neurosurg Focus. 2000 Dec 15;9(6):e7.

PMID:
16817690
6.

Development of improved Sindbis virus-based DNA expression vector.

Yamanaka R, Xanthopoulos KG.

DNA Cell Biol. 2004 Feb;23(2):75-80.

PMID:
15000747
7.
8.

Administration of interleukin-12 and -18 enhancing the antitumor immunity of genetically modified dendritic cells that had been pulsed with Semliki forest virus-mediated tumor complementary DNA.

Yamanaka R, Yajima N, Tsuchiya N, Honma J, Tanaka R, Ramsey J, Blaese M, Xanthopoulos KG.

J Neurosurg. 2002 Nov;97(5):1184-90.

PMID:
12450042
9.

Marked enhancement of antitumor immune responses in mouse brain tumor models by genetically modified dendritic cells producing Semliki Forest virus-mediated interleukin-12.

Yamanaka R, Zullo SA, Ramsey J, Yajima N, Tsuchiya N, Tanaka R, Blaese M, Xanthopoulos KG.

J Neurosurg. 2002 Sep;97(3):611-8.

PMID:
12296646
10.

Induction of therapeutic antitumor antiangiogenesis by intratumoral injection of genetically engineered endostatin-producing Semliki Forest virus.

Yamanaka R, Zullo SA, Ramsey J, Onodera M, Tanaka R, Blaese M, Xanthopoulos KG.

Cancer Gene Ther. 2001 Oct;8(10):796-802.

11.
12.

Developing targets for drug discovery using genome-wide gene trapping and ultra-sensitive beta-lactamase reporters.

Liyanage M, Zamiara EM, Mandurrago B, Riley M, Sanders P, Welchlin HL, Xanthopoulos KG.

Proc West Pharmacol Soc. 1999;42:123-6. No abstract available.

PMID:
10697713
13.

Hunting with traps: genome-wide strategies for gene discovery and functional analysis.

Durick K, Mendlein J, Xanthopoulos KG.

Genome Res. 1999 Nov;9(11):1019-25. Review.

14.

Synergistic activation of the human Btk promoter by transcription factors Sp1/3 and PU.1.

Müller S, Maas A, Islam TC, Sideras P, Suske G, Philipsen S, Xanthopoulos KG, Hendriks RW, Smith CI.

Biochem Biophys Res Commun. 1999 Jun 7;259(2):364-9.

PMID:
10362515
15.
16.

CCAAT/enhancer binding proteins are critical components of the transcriptional regulation of hematopoiesis (Review).

Yamanaka R, Lekstrom-Himes J, Barlow C, Wynshaw-Boris A, Xanthopoulos KG.

Int J Mol Med. 1998 Jan;1(1):213-21. Review.

PMID:
9852222
17.

Generation of a conditionally neo(r)-containing retroviral producer cell line: effects of neo(r) on retroviral titer and transgene expression.

Wildner O, Candotti F, Krecko EG, Xanthopoulos KG, Ramsey WJ, Blaese RM.

Gene Ther. 1998 May;5(5):684-91.

18.

Biological role of the CCAAT/enhancer-binding protein family of transcription factors.

Lekstrom-Himes J, Xanthopoulos KG.

J Biol Chem. 1998 Oct 30;273(44):28545-8. Review.

19.

Hepatocytes deficient in CCAAT/enhancer binding protein alpha (C/EBP alpha) exhibit both hepatocyte and biliary epithelial cell character.

Tomizawa M, Garfield S, Factor V, Xanthopoulos KG.

Biochem Biophys Res Commun. 1998 Aug 10;249(1):1-5.

PMID:
9705820
20.

Semliki Forest virus-mediated production of retroviral vector RNA in retroviral packaging cells.

Wahlfors JJ, Xanthopoulos KG, Morgan RA.

Hum Gene Ther. 1997 Nov 20;8(17):2031-41.

PMID:
9414252
21.

Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice.

Yamanaka R, Barlow C, Lekstrom-Himes J, Castilla LH, Liu PP, Eckhaus M, Decker T, Wynshaw-Boris A, Xanthopoulos KG.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13187-92.

22.

Targeted expression of Cre recombinase to adipose tissue of transgenic mice directs adipose-specific excision of loxP-flanked gene segments.

Barlow C, Schroeder M, Lekstrom-Himes J, Kylefjord H, Deng CX, Wynshaw-Boris A, Spiegelman BM, Xanthopoulos KG.

Nucleic Acids Res. 1997 Jun 15;25(12):2543-5. Erratum in: Nucleic Acids Res 1997 Nov 1;25(21):4429.

23.

CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing.

Yamanaka R, Kim GD, Radomska HS, Lekstrom-Himes J, Smith LT, Antonson P, Tenen DG, Xanthopoulos KG.

Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6462-7.

24.
25.

Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha.

Flodby P, Barlow C, Kylefjord H, Ahrlund-Richter L, Xanthopoulos KG.

J Biol Chem. 1996 Oct 4;271(40):24753-60.

26.

Suicide gene therapy for plasma cell tumors.

Dilber MS, Abedi MR, Björkstrand B, Christensson B, Gahrton G, Xanthopoulos KG, Smith CI.

Blood. 1996 Sep 15;88(6):2192-200.

PMID:
8822939
28.

Retroviral-mediated gene transfer into human bone marrow stromal cells: studies of efficiency and in vivo survival in SCID mice.

Li KJ, Dilber MS, Abedi MR, Björkstrand B, Smith CI, Garoff H, Gahrton G, Xanthopoulos KG.

Eur J Haematol. 1995 Nov;55(5):302-6.

PMID:
7493676
29.
30.
31.
32.

Basic fibroblast growth factor increases retroviral-mediated gene transfer into human hematopoietic peripheral blood progenitor cells.

Dilber MS, Björkstrand B, Li KJ, Smith CI, Xanthopoulos KG, Gahrton G.

Exp Hematol. 1994 Nov;22(12):1129-33.

PMID:
7523165
33.

Retroviral-mediated gene transfer into human myeloma cells.

Björkstrand B, Dilber MS, Smith CI, Gahrton G, Xanthopoulos KG.

Br J Haematol. 1994 Oct;88(2):325-31.

PMID:
7803277
34.

Retroviral-mediated gene transfer of CD34-enriched bone marrow and peripheral blood cells during autologous stem cell transplantation for multiple myeloma.

Björkstrand B, Gahrton G, Dilber MS, Ljungman P, Smith CI, Xanthopoulos KG.

Hum Gene Ther. 1994 Oct;5(10):1279-86. No abstract available.

PMID:
7531504
35.

Gene regulation in rodent hepatocytes during development, differentiation and disease.

Xanthopoulos KG, Mirkovitch J.

Eur J Biochem. 1993 Sep 1;216(2):353-60. Review.

36.

Differential patterns of expression of three C/EBP isoforms, HNF-1, and HNF-4 after partial hepatectomy in rats.

Flodby P, Antonson P, Barlow C, Blanck A, Porsch-Hällström I, Xanthopoulos KG.

Exp Cell Res. 1993 Sep;208(1):248-56.

PMID:
8359219
37.
38.

Differential adrenergic regulation of C/EBP alpha and C/EBP beta in brown adipose tissue.

Rehnmark S, Antonson P, Xanthopoulos KG, Jacobsson A.

FEBS Lett. 1993 Mar 8;318(3):235-41.

39.

Transiently and stably introduced CCAAT/enhancer-binding-protein genes are constitutively expressed in cultured cells.

Xanthopoulos KG, Cannon PD, Robinson GS, Mirkovitch J, Darnell JE Jr.

Eur J Biochem. 1992 Sep 1;208(2):501-9.

40.

Transcriptional control in hepatocytes of normal and c14CoS albino deletion mice.

Tönjes RR, Xanthopoulos KG, Darnell JE Jr, Paul D.

EMBO J. 1992 Jan;11(1):127-33.

41.

The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription.

Xanthopoulos KG, Prezioso VR, Chen WS, Sladek FM, Cortese R, Darnell JE Jr.

Proc Natl Acad Sci U S A. 1991 May 1;88(9):3807-11.

42.
43.

A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation.

Herrera R, Ro HS, Robinson GS, Xanthopoulos KG, Spiegelman BM.

Mol Cell Biol. 1989 Dec;9(12):5331-9.

44.

Cell-specific transcriptional control of the mouse DNA-binding protein mC/EBP.

Xanthopoulos KG, Mirkovitch J, Decker T, Kuo CF, Darnell JE Jr.

Proc Natl Acad Sci U S A. 1989 Jun;86(11):4117-21.

45.

The mouse Cebp gene encoding a DNA-binding protein is polymorphic and is located on chromosome 7.

Xanthopoulos KG, Mirkovitch J, Friedman JM, Darnell JE Jr.

Cytogenet Cell Genet. 1989;50(2-3):174-5.

PMID:
2570675
46.
47.

The structure of the gene for cecropin B, an antibacterial immune protein from Hyalophora cecropia.

Xanthopoulos KG, Lee JY, Gan R, Kockum K, Faye I, Boman HG.

Eur J Biochem. 1988 Mar 1;172(2):371-6.

48.
49.

One factor recognizes the liver-specific enhancers in alpha 1-antitrypsin and transthyretin genes.

Grayson DR, Costa RH, Xanthopoulos KG, Darnell JE.

Science. 1988 Feb 12;239(4841 Pt 1):786-8.

PMID:
3257586
50.

Analysis by in situ hybridization of cells expressing mRNA for interleukin 4 in the developing thymus and in peripheral lymphocytes from mice.

Sideras P, Funa K, Zalcberg-Quintana I, Xanthopoulos KG, Kisielow P, Palacios R.

Proc Natl Acad Sci U S A. 1988 Jan;85(1):218-21.

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