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Items: 2

1.

Xanthohumol exhibits anti-myeloma activity in vitro through inhibition of cell proliferation, induction of apoptosis via the ERK and JNK-dependent mechanism, and suppression of sIL-6R and VEGF production.

Sławińska-Brych A, Zdzisińska B, Czerwonka A, Mizerska-Kowalska M, Dmoszyńska-Graniczka M, Stepulak A, Gagoś M.

Biochim Biophys Acta Gen Subj. 2019 Nov;1863(11):129408. doi: 10.1016/j.bbagen.2019.08.001. Epub 2019 Aug 3.

PMID:
31386885
2.

Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells.

Harikumar KB, Kunnumakkara AB, Ahn KS, Anand P, Krishnan S, Guha S, Aggarwal BB.

Blood. 2009 Feb 26;113(9):2003-13. doi: 10.1182/blood-2008-04-151944. Epub 2008 Oct 24.

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