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Items: 8


Fine-Tuning of σE Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli.

Hart EM, O'Connell A, Tang K, Wzorek JS, Grabowicz M, Kahne D, Silhavy TJ.

J Bacteriol. 2019 May 8;201(11). pii: e00745-18. doi: 10.1128/JB.00745-18. Print 2019 Jun 1.


Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion.

Lee J, Sutterlin HA, Wzorek JS, Mandler MD, Hagan CL, Grabowicz M, Tomasek D, May MD, Hart EM, Silhavy TJ, Kahne D.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2359-2364. doi: 10.1073/pnas.1711727115. Epub 2018 Feb 20.


Membrane integration of an essential β-barrel protein prerequires burial of an extracellular loop.

Wzorek JS, Lee J, Tomasek D, Hagan CL, Kahne DE.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2598-2603. doi: 10.1073/pnas.1616576114. Epub 2017 Feb 21.


Characterization of a stalled complex on the β-barrel assembly machine.

Lee J, Xue M, Wzorek JS, Wu T, Grabowicz M, Gronenberg LS, Sutterlin HA, Davis RM, Ruiz N, Silhavy TJ, Kahne DE.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8717-22. doi: 10.1073/pnas.1604100113. Epub 2016 Jul 20.


Inhibition of the β-barrel assembly machine by a peptide that binds BamD.

Hagan CL, Wzorek JS, Kahne D.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2011-6. doi: 10.1073/pnas.1415955112. Epub 2015 Feb 2.


Approach to the tricyclic core of the tigliane-daphnane diterpenes. Concerning the utility of transannular aldol additions.

Catino AJ, Sherlock A, Shieh P, Wzorek JS, Evans DA.

Org Lett. 2013 Jul 5;15(13):3330-3. doi: 10.1021/ol401367h. Epub 2013 Jun 20.


Total synthesis of (-)-nakadomarin A.

Bonazzi S, Cheng B, Wzorek JS, Evans DA.

J Am Chem Soc. 2013 Jun 26;135(25):9338-41. doi: 10.1021/ja404673s. Epub 2013 Jun 17.


A macrocyclic approach to tetracycline natural products. Investigation of transannular alkylations and Michael additions.

Wzorek JS, Knöpfel TF, Sapountzis I, Evans DA.

Org Lett. 2012 Dec 7;14(23):5840-3. doi: 10.1021/ol302691j. Epub 2012 Nov 12.


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