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Items: 1 to 50 of 112

1.

Benchmarking Brain-Computer Interfaces Outside the Laboratory: The Cybathlon 2016.

Novak D, Sigrist R, Gerig NJ, Wyss D, Bauer R, Götz U, Riener R.

Front Neurosci. 2018 Jan 11;11:756. doi: 10.3389/fnins.2017.00756. eCollection 2017.

2.

Posterior Approach for Revascularization in Blunt Popliteal Vessel Injury.

Makaloski V, Stellmes A, Wyss D, Weiss S, Becker D, Wyss TR, Schmidli J.

Ann Vasc Surg. 2018 Apr;48:89-96. doi: 10.1016/j.avsg.2017.10.019. Epub 2017 Dec 5.

PMID:
29217442
3.

Management of popliteal vascular injury associated with traumatic knee injury via posterior approach.

Makaloski V, Stellmes A, Wyss D, Weiss S, Becker D, Wyss TR, Schmidli J.

J Cardiovasc Surg (Torino). 2017 Aug 29. doi: 10.23736/S0021-9509.17.10040-6. [Epub ahead of print] No abstract available.

PMID:
28849899
4.

The Effects of Acute Intense Physical Exercise on Postural Stability in Children With Cerebral Palsy.

Leineweber MJ, Wyss D, Dufour SK, Gane C, Zabjek K, Bouyer LJ, Maltais DB, Voisin JI, Andrysek J.

Adapt Phys Activ Q. 2016 Jul;33(3):271-82. doi: 10.1123/APAQ.2015-0115.

PMID:
27623610
5.

NMR Binding and Functional Assays for Detecting Inhibitors of S. aureus MnaA.

Hou Y, Mayhood T, Sheth P, Tan CM, Labroli M, Su J, Wyss DF, Roemer T, McCoy MA.

J Biomol Screen. 2016 Jul;21(6):579-89. doi: 10.1177/1087057116640199. Epub 2016 Mar 29.

PMID:
27028606
6.

Acute Physical Exercise Affects Cognitive Functioning in Children With Cerebral Palsy.

Maltais DB, Gane C, Dufour SK, Wyss D, Bouyer LJ, McFadyen BJ, Zabjek K, Andrysek J, Voisen JI.

Pediatr Exerc Sci. 2016 May;28(2):304-11. doi: 10.1123/pes.2015-0110. Epub 2015 Oct 23.

PMID:
26502458
7.

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.

Gao H, Korn JM, Ferretti S, Monahan JE, Wang Y, Singh M, Zhang C, Schnell C, Yang G, Zhang Y, Balbin OA, Barbe S, Cai H, Casey F, Chatterjee S, Chiang DY, Chuai S, Cogan SM, Collins SD, Dammassa E, Ebel N, Embry M, Green J, Kauffmann A, Kowal C, Leary RJ, Lehar J, Liang Y, Loo A, Lorenzana E, Robert McDonald E 3rd, McLaughlin ME, Merkin J, Meyer R, Naylor TL, Patawaran M, Reddy A, Röelli C, Ruddy DA, Salangsang F, Santacroce F, Singh AP, Tang Y, Tinetto W, Tobler S, Velazquez R, Venkatesan K, Von Arx F, Wang HQ, Wang Z, Wiesmann M, Wyss D, Xu F, Bitter H, Atadja P, Lees E, Hofmann F, Li E, Keen N, Cozens R, Jensen MR, Pryer NK, Williams JA, Sellers WR.

Nat Med. 2015 Nov;21(11):1318-25. doi: 10.1038/nm.3954. Epub 2015 Oct 19.

PMID:
26479923
8.

NMR screening in fragment-based drug design: a practical guide.

Kim HY, Wyss DF.

Methods Mol Biol. 2015;1263:197-208. doi: 10.1007/978-1-4939-2269-7_16.

PMID:
25618347
9.

The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors.

Labroli MA, Dwyer MP, Shen R, Popovici-Muller J, Pu Q, Wyss D, McCoy M, Barrett D, Davis N, Seghezzi W, Shanahan F, Taricani L, Beaumont M, Malinao MC, Parry D, Guzi TJ.

Bioorg Med Chem. 2014 Apr 1;22(7):2303-10. doi: 10.1016/j.bmc.2014.02.007. Epub 2014 Feb 15.

PMID:
24588962
10.

[Ventilator weaning requires interprofessional management].

Hürlimann B, Spichiger E, Ott S, Schild A, Leuenberger JS, Wyss D.

Krankenpfl Soins Infirm. 2013;106(11):34-5. German. No abstract available.

PMID:
24479226
11.

Priorities in lower limb prosthetic service delivery based on an international survey of prosthetists in low- and high-income countries.

Wyss D, Lindsay S, Cleghorn WL, Andrysek J.

Prosthet Orthot Int. 2015 Apr;39(2):102-11. doi: 10.1177/0309364613513824. Epub 2013 Dec 13.

PMID:
24335154
12.

A preliminary study into the effects of pelvic rotations on upper body lateral translation.

Pennycott A, Wyss D, Vallery H, Riener R.

IEEE Int Conf Rehabil Robot. 2013 Jun;2013:6650490. doi: 10.1109/ICORR.2013.6650490.

PMID:
24187307
13.

A novel body weight support system extension: initial concept and simulation study.

Pennycott A, Vallery H, Wyss D, Spindler M, Dewarrat A, Riener R.

IEEE Int Conf Rehabil Robot. 2013 Jun;2013:6650489. doi: 10.1109/ICORR.2013.6650489.

PMID:
24187306
14.

Ipso-hydroxylation and subsequent fragmentation: a novel microbial strategy to eliminate sulfonamide antibiotics.

Ricken B, Corvini PF, Cichocka D, Parisi M, Lenz M, Wyss D, Martínez-Lavanchy PM, Müller JA, Shahgaldian P, Tulli LG, Kohler HP, Kolvenbach BA.

Appl Environ Microbiol. 2013 Sep;79(18):5550-8. doi: 10.1128/AEM.00911-13. Epub 2013 Jul 8.

15.

Towards more effective robotic gait training for stroke rehabilitation: a review.

Pennycott A, Wyss D, Vallery H, Klamroth-Marganska V, Riener R.

J Neuroeng Rehabil. 2012 Sep 7;9:65. doi: 10.1186/1743-0003-9-65. Review.

16.

Global functioning and disability in dissociative disorders.

Mueller-Pfeiffer C, Rufibach K, Perron N, Wyss D, Kuenzler C, Prezewowsky C, Pitman RK, Rufer M.

Psychiatry Res. 2012 Dec 30;200(2-3):475-81. doi: 10.1016/j.psychres.2012.04.028. Epub 2012 May 10.

PMID:
22578820
17.

The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases.

Hardaker L, Bahra P, de Billy BC, Freeman M, Kupfer N, Wyss D, Trifilieff A.

Respir Res. 2012 Apr 4;13:30. doi: 10.1186/1465-9921-13-30.

18.

Effects of added inertia and body weight support on lateral balance control during walking.

Pennycott A, Wyss D, Vallery H, Riener R.

IEEE Int Conf Rehabil Robot. 2011;2011:5975415. doi: 10.1109/ICORR.2011.5975415.

PMID:
22275618
19.

Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors.

Huang X, Shipps GW Jr, Cheng CC, Spacciapoli P, Zhang X, McCoy MA, Wyss DF, Yang X, Achab A, Soucy K, Montavon DK, Murphy DM, Whitehurst CE.

ACS Med Chem Lett. 2011 Jun 24;2(8):632-7. doi: 10.1021/ml200113y. eCollection 2011 Aug 11.

20.

Combining NMR and X-ray crystallography in fragment-based drug discovery: discovery of highly potent and selective BACE-1 inhibitors.

Wyss DF, Wang YS, Eaton HL, Strickland C, Voigt JH, Zhu Z, Stamford AW.

Top Curr Chem. 2012;317:83-114. doi: 10.1007/128_2011_183. Review.

PMID:
21647837
21.

Noninvasive assessment of bleomycin-induced lung injury and the effects of short-term glucocorticosteroid treatment in rats using MRI.

Babin AL, Cannet C, Gérard C, Wyss D, Page CP, Beckmann N.

J Magn Reson Imaging. 2011 Mar;33(3):603-14. doi: 10.1002/jmri.22476.

PMID:
21563244
22.

Effective progression of nuclear magnetic resonance-detected fragment hits.

Eaton HL, Wyss DF.

Methods Enzymol. 2011;493:447-68. doi: 10.1016/B978-0-12-381274-2.00017-0.

PMID:
21371601
23.

Pyridine Carboxamides: Potent Palm Site Inhibitors of HCV NS5B Polymerase.

Cheng CC, Huang X, Shipps GW Jr, Wang YS, Wyss DF, Soucy KA, Jiang CK, Agrawal S, Ferrari E, He Z, Huang HC.

ACS Med Chem Lett. 2010 Aug 17;1(9):466-71. doi: 10.1021/ml100128h. eCollection 2010 Dec 9.

24.

Pharmacological characterisation of anti-inflammatory compounds in acute and chronic mouse models of cigarette smoke-induced inflammation.

Wan WY, Morris A, Kinnear G, Pearce W, Mok J, Wyss D, Stevenson CS.

Respir Res. 2010 Sep 18;11:126. doi: 10.1186/1465-9921-11-126.

25.

Addressing ethical dilemmas in the clinical care of adolescents: an international view.

Michaud PA, Berg-Kelly K, Macfarlane A, Renteria SC, Wyss D, Benaroyo L.

Adolesc Med State Art Rev. 2009 Dec;20(3):949-60, x. Review.

PMID:
20653211
26.

The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist.

Baur F, Beattie D, Beer D, Bentley D, Bradley M, Bruce I, Charlton SJ, Cuenoud B, Ernst R, Fairhurst RA, Faller B, Farr D, Keller T, Fozard JR, Fullerton J, Garman S, Hatto J, Hayden C, He H, Howes C, Janus D, Jiang Z, Lewis C, Loeuillet-Ritzler F, Moser H, Reilly J, Steward A, Sykes D, Tedaldi L, Trifilieff A, Tweed M, Watson S, Wissler E, Wyss D.

J Med Chem. 2010 May 13;53(9):3675-84. doi: 10.1021/jm100068m.

PMID:
20402514
27.

Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitors.

Wang YS, Strickland C, Voigt JH, Kennedy ME, Beyer BM, Senior MM, Smith EM, Nechuta TL, Madison VS, Czarniecki M, McKittrick BA, Stamford AW, Parker EM, Hunter JC, Greenlee WJ, Wyss DF.

J Med Chem. 2010 Feb 11;53(3):942-50. doi: 10.1021/jm901472u.

PMID:
20043700
28.

Discovery of cyclic acylguanidines as highly potent and selective beta-site amyloid cleaving enzyme (BACE) inhibitors: Part I--inhibitor design and validation.

Zhu Z, Sun ZY, Ye Y, Voigt J, Strickland C, Smith EM, Cumming J, Wang L, Wong J, Wang YS, Wyss DF, Chen X, Kuvelkar R, Kennedy ME, Favreau L, Parker E, McKittrick BA, Stamford A, Czarniecki M, Greenlee W, Hunter JC.

J Med Chem. 2010 Feb 11;53(3):951-65. doi: 10.1021/jm901408p.

PMID:
20043696
29.

Comparison of cigarette smoke-induced acute inflammation in multiple strains of mice and the effect of a matrix metalloproteinase inhibitor on these responses.

Morris A, Kinnear G, Wan WY, Wyss D, Bahra P, Stevenson CS.

J Pharmacol Exp Ther. 2008 Dec;327(3):851-62. doi: 10.1124/jpet.108.140848. Epub 2008 Sep 19.

PMID:
18806126
30.

Synergistic effect of formoterol and mometasone in a mouse model of allergic lung inflammation.

Wyss D, Bonneau O, Trifilieff A.

Br J Pharmacol. 2007 Sep;152(1):83-90. Epub 2007 Jul 9.

31.

Is restricted femoral navigation sufficient for accuracy of total knee arthroplasty?

Zumstein MA, Frauchiger L, Wyss D, Hess R, Ballmer PM.

Clin Orthop Relat Res. 2006 Oct;451:80-6.

PMID:
16691146
32.

Characterization of autocatalytic conversion of precursor BACE1 by heteronuclear NMR spectroscopy.

Wang YS, Beyer BM, Senior MM, Wyss DF.

Biochemistry. 2005 Dec 20;44(50):16594-601.

PMID:
16342950
33.

Effect of adenosine A2A receptor activation in murine models of respiratory disorders.

Bonneau O, Wyss D, Ferretti S, Blaydon C, Stevenson CS, Trifilieff A.

Am J Physiol Lung Cell Mol Physiol. 2006 May;290(5):L1036-43. Epub 2005 Dec 9.

34.

Screening of protein kinases by ATP-STD NMR spectroscopy.

McCoy MA, Senior MM, Wyss DF.

J Am Chem Soc. 2005 Jun 8;127(22):7978-9.

PMID:
15926798
35.
36.

Backbone resonance assignments of the 45.3 kDa catalytic domain of human BACE1.

Liu D, Wang YS, Gesell JJ, Wilson E, Beyer BM, Wyss DF.

J Biomol NMR. 2004 Jul;29(3):425-6. No abstract available.

PMID:
15213451
37.

Solution structure of the hypothetical protein SAV1595 from Staphylococcus aureus, a putative RNA binding protein.

Liu D, Wyss DF.

J Biomol NMR. 2004 Jul;29(3):391-4. No abstract available.

PMID:
15213438
38.

Competition STD NMR for the detection of high-affinity ligands and NMR-based screening.

Wang YS, Liu D, Wyss DF.

Magn Reson Chem. 2004 Jun;42(6):485-9.

PMID:
15137040
39.

Non-peptidic small-molecule inhibitors of the single-chain hepatitis C virus NS3 protease/NS4A cofactor complex discovered by structure-based NMR screening.

Wyss DF, Arasappan A, Senior MM, Wang YS, Beyer BM, Njoroge FG, McCoy MA.

J Med Chem. 2004 May 6;47(10):2486-98.

PMID:
15115392
40.

Anterior femoroacetabular impingement: part II. Midterm results of surgical treatment.

Beck M, Leunig M, Parvizi J, Boutier V, Wyss D, Ganz R.

Clin Orthop Relat Res. 2004 Jan;(418):67-73.

PMID:
15043095
41.

Sequence-specific assignments of methyl groups in high-molecular weight proteins.

Yang D, Zheng Y, Liu D, Wyss DF.

J Am Chem Soc. 2004 Mar 31;126(12):3710-1.

PMID:
15038713
42.
43.

Double-stranded DNA-induced localized unfolding of HCV NS3 helicase subdomain 2.

Liu D, Windsor WT, Wyss DF.

Protein Sci. 2003 Dec;12(12):2757-67.

44.

Structure-guided applications in drug discovery.

Wyss DF.

Drug Discov Today. 2003 Oct 15;8(20):924-6. No abstract available.

PMID:
14554155
45.

Solution structure of the hypothetical protein YqgF from Escherichia coli reveals an RNAse H fold.

Liu D, Wang YS, Wyss DF.

J Biomol NMR. 2003 Dec;27(4):389-92. No abstract available.

PMID:
14512736
46.

Flexible lid to the p53-binding domain of human Mdm2: implications for p53 regulation.

McCoy MA, Gesell JJ, Senior MM, Wyss DF.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1645-8. Epub 2003 Jan 27.

47.

Backbone 1H, 15N and 13C resonance assignments of the Staphylococcus aureus acyl carrier protein synthase (AcpS).

Liu D, Black T, Macinga DR, Palermo R, Wyss DF.

J Biomol NMR. 2002 Nov;24(3):273-4. No abstract available.

PMID:
12522316
48.
49.

Structure, biology, and therapeutic implications of pegylated interferon alpha-2b.

Youngster S, Wang YS, Grace M, Bausch J, Bordens R, Wyss DF.

Curr Pharm Des. 2002;8(24):2139-57. Review.

PMID:
12369859
50.

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