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Items: 13

1.

MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors.

Sells TB, Chau R, Ecsedy JA, Gershman RE, Hoar K, Huck J, Janowick DA, Kadambi VJ, LeRoy PJ, Stirling M, Stroud SG, Vos TJ, Weatherhead GS, Wysong DR, Zhang M, Balani SK, Bolen JB, Manfredi MG, Claiborne CF.

ACS Med Chem Lett. 2015 Apr 22;6(6):630-4. doi: 10.1021/ml500409n. eCollection 2015 Jun 11.

2.

Characterization of Alisertib (MLN8237), an investigational small-molecule inhibitor of aurora A kinase using novel in vivo pharmacodynamic assays.

Manfredi MG, Ecsedy JA, Chakravarty A, Silverman L, Zhang M, Hoar KM, Stroud SG, Chen W, Shinde V, Huck JJ, Wysong DR, Janowick DA, Hyer ML, Leroy PJ, Gershman RE, Silva MD, Germanos MS, Bolen JB, Claiborne CF, Sells TB.

Clin Cancer Res. 2011 Dec 15;17(24):7614-24. doi: 10.1158/1078-0432.CCR-11-1536. Epub 2011 Oct 20.

3.

Analysis of two pharmacodynamic biomarkers using acoustic micro magnetic particles on the ViBE bioanalyzer.

Yan ZH, Madison LL, Burkhardt A, Yu J, Tayber O, Li Z, Wu D, Loke HK, Wysong DR, Iartchouk N, Smith MD, Kuranda M, Li P, Bembenek ME.

Anal Biochem. 2011 Mar 1;410(1):13-8. doi: 10.1016/j.ab.2010.11.012. Epub 2010 Nov 13.

PMID:
21078283
4.

The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents.

Wysong DR, Chakravarty A, Hoar K, Ecsedy JA.

Cell Cycle. 2009 Mar 15;8(6):876-88. Epub 2009 Mar 21.

PMID:
19221504
5.

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase.

Manfredi MG, Ecsedy JA, Meetze KA, Balani SK, Burenkova O, Chen W, Galvin KM, Hoar KM, Huck JJ, LeRoy PJ, Ray ET, Sells TB, Stringer B, Stroud SG, Vos TJ, Weatherhead GS, Wysong DR, Zhang M, Bolen JB, Claiborne CF.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):4106-11. Epub 2007 Feb 23.

6.

Novel small-molecule inhibitors of RNA polymerase III.

Wu L, Pan J, Thoroddsen V, Wysong DR, Blackman RK, Bulawa CE, Gould AE, Ocain TD, Dick LR, Errada P, Dorr PK, Parkinson T, Wood T, Kornitzer D, Weissman Z, Willis IM, McGovern K.

Eukaryot Cell. 2003 Apr;2(2):256-64.

7.

Cloning and sequencing of a Candida albicans catalase gene and effects of disruption of this gene.

Wysong DR, Christin L, Sugar AM, Robbins PW, Diamond RD.

Infect Immun. 1998 May;66(5):1953-61.

8.

Human platelets damage Aspergillus fumigatus hyphae and may supplement killing by neutrophils.

Christin L, Wysong DR, Meshulam T, Hastey R, Simons ER, Diamond RD.

Infect Immun. 1998 Mar;66(3):1181-9.

9.

Mechanisms and target sites of damage in killing of Candida albicans hyphae by human polymorphonuclear neutrophils.

Christin L, Wysong DR, Meshulam T, Wang S, Diamond RD.

J Infect Dis. 1997 Dec;176(6):1567-78.

PMID:
9395369
12.
13.

Electrophoretic and immunoblot analyses of Rhizopus arrhizus antigens.

Wysong DR, Waldorf AR.

J Clin Microbiol. 1987 Feb;25(2):358-63.

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