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Items: 26

1.

Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae.

Wyres KL, Wick RR, Judd LM, Froumine R, Tokolyi A, Gorrie CL, Lam MMC, Duchêne S, Jenney A, Holt KE.

PLoS Genet. 2019 Apr 15;15(4):e1008114. doi: 10.1371/journal.pgen.1008114. eCollection 2019 Apr.

2.

Convergence of virulence and MDR in a single plasmid vector in MDR Klebsiella pneumoniae ST15.

Lam MMC, Wyres KL, Wick RR, Judd LM, Fostervold A, Holt KE, Löhr IH.

J Antimicrob Chemother. 2019 Feb 15. pii: dkz028. doi: 10.1093/jac/dkz028. [Epub ahead of print]

3.

Small IncQ1 and Col-Like Plasmids Harboring bla KPC-2 and Non-Tn4401 Elements (NTEKPC-IId) in High-Risk Lineages of Klebsiella pneumoniae CG258.

Cerdeira LT, Lam MMC, Wyres KL, Wick RR, Judd LM, Lopes R, Ribas RM, Morais MM, Holt KE, Lincopan N.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e02140-18. doi: 10.1128/AAC.02140-18. Print 2019 Mar. No abstract available.

4.

Comment on: CG258 Klebsiella pneumoniae isolates without β-lactam resistance at the onset of the carbapenem-resistant Enterobacteriaceae epidemic in New York City.

Wyres KL, Lam MMC, Holt KE.

J Antimicrob Chemother. 2019 Mar 1;74(3):831-833. doi: 10.1093/jac/dky472. No abstract available.

5.

Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307.

Wyres KL, Hawkey J, Hetland MAK, Fostervold A, Wick RR, Judd LM, Hamidian M, Howden BP, Löhr IH, Holt KE.

J Antimicrob Chemother. 2019 Mar 1;74(3):577-581. doi: 10.1093/jac/dky492.

6.

Tracking key virulence loci encoding aerobactin and salmochelin siderophore synthesis in Klebsiella pneumoniae.

Lam MMC, Wyres KL, Judd LM, Wick RR, Jenney A, Brisse S, Holt KE.

Genome Med. 2018 Oct 29;10(1):77. doi: 10.1186/s13073-018-0587-5.

7.

Best practice data life cycle approaches for the life sciences.

Griffin PC, Khadake J, LeMay KS, Lewis SE, Orchard S, Pask A, Pope B, Roessner U, Russell K, Seemann T, Treloar A, Tyagi S, Christiansen JH, Dayalan S, Gladman S, Hangartner SB, Hayden HL, Ho WWH, Keeble-Gagnère G, Korhonen PK, Neish P, Prestes PR, Richardson MF, Watson-Haigh NS, Wyres KL, Young ND, Schneider MV.

Version 2. F1000Res. 2017 Aug 31 [revised 2018 Jan 1];6:1618. doi: 10.12688/f1000research.12344.2. eCollection 2017.

8.

Population genomics of hypervirulent Klebsiella pneumoniae clonal-group 23 reveals early emergence and rapid global dissemination.

Lam MMC, Wyres KL, Duchêne S, Wick RR, Judd LM, Gan YH, Hoh CH, Archuleta S, Molton JS, Kalimuddin S, Koh TH, Passet V, Brisse S, Holt KE.

Nat Commun. 2018 Jul 13;9(1):2703. doi: 10.1038/s41467-018-05114-7.

9.

Genetic diversity, mobilisation and spread of the yersiniabactin-encoding mobile element ICEKp in Klebsiella pneumoniae populations.

Lam MMC, Wick RR, Wyres KL, Gorrie CL, Judd LM, Jenney AWJ, Brisse S, Holt KE.

Microb Genom. 2018 Sep;4(9). doi: 10.1099/mgen.0.000196. Epub 2018 Jul 9.

10.

Klebsiella pneumoniae as a key trafficker of drug resistance genes from environmental to clinically important bacteria.

Wyres KL, Holt KE.

Curr Opin Microbiol. 2018 Oct;45:131-139. doi: 10.1016/j.mib.2018.04.004. Epub 2018 May 1. Review.

11.

Kaptive Web: User-Friendly Capsule and Lipopolysaccharide Serotype Prediction for Klebsiella Genomes.

Wick RR, Heinz E, Holt KE, Wyres KL.

J Clin Microbiol. 2018 May 25;56(6). pii: e00197-18. doi: 10.1128/JCM.00197-18. Print 2018 Jun.

12.

Antimicrobial-Resistant Klebsiella pneumoniae Carriage and Infection in Specialized Geriatric Care Wards Linked to Acquisition in the Referring Hospital.

Gorrie CL, Mirceta M, Wick RR, Judd LM, Wyres KL, Thomson NR, Strugnell RA, Pratt NF, Garlick JS, Watson KM, Hunter PC, McGloughlin SA, Spelman DW, Jenney AWJ, Holt KE.

Clin Infect Dis. 2018 Jul 2;67(2):161-170. doi: 10.1093/cid/ciy027.

13.

The diversity of Klebsiella pneumoniae surface polysaccharides.

Follador R, Heinz E, Wyres KL, Ellington MJ, Kowarik M, Holt KE, Thomson NR.

Microb Genom. 2016 Aug 25;2(8):e000073. doi: 10.1099/mgen.0.000073. eCollection 2016 Aug.

14.

Identification of Klebsiella capsule synthesis loci from whole genome data.

Wyres KL, Wick RR, Gorrie C, Jenney A, Follador R, Thomson NR, Holt KE.

Microb Genom. 2016 Dec 12;2(12):e000102. doi: 10.1099/mgen.0.000102. eCollection 2016 Dec.

15.

Klebsiella pneumoniae Population Genomics and Antimicrobial-Resistant Clones.

Wyres KL, Holt KE.

Trends Microbiol. 2016 Dec;24(12):944-956. doi: 10.1016/j.tim.2016.09.007. Epub 2016 Oct 11. Review.

16.

Differential host susceptibility and bacterial virulence factors driving Klebsiella liver abscess in an ethnically diverse population.

Lee IR, Molton JS, Wyres KL, Gorrie C, Wong J, Hoh CH, Teo J, Kalimuddin S, Lye DC, Archuleta S, Holt KE, Gan YH.

Sci Rep. 2016 Jul 13;6:29316. doi: 10.1038/srep29316.

17.

Paradoxical Hypersusceptibility of Drug-resistant Mycobacteriumtuberculosis to β-lactam Antibiotics.

Cohen KA, El-Hay T, Wyres KL, Weissbrod O, Munsamy V, Yanover C, Aharonov R, Shaham O, Conway TC, Goldschmidt Y, Bishai WR, Pym AS.

EBioMedicine. 2016 Jul;9:170-179. doi: 10.1016/j.ebiom.2016.05.041. Epub 2016 Jun 1.

18.

A platform for leveraging next generation sequencing for routine microbiology and public health use.

Rusu LI, Wyres KL, Reumann M, Queiroz C, Bojovschi A, Conway T, Garg S, Edwards DJ, Hogg G, Holt KE.

Health Inf Sci Syst. 2015 Feb 24;3(Suppl 1 HISA Big Data in Biomedicine and Healthcare 2013 Con):S7. doi: 10.1186/2047-2501-3-S1-S7. eCollection 2015.

19.

Extensive Capsule Locus Variation and Large-Scale Genomic Recombination within the Klebsiella pneumoniae Clonal Group 258.

Wyres KL, Gorrie C, Edwards DJ, Wertheim HF, Hsu LY, Van Kinh N, Zadoks R, Baker S, Holt KE.

Genome Biol Evol. 2015 Apr 10;7(5):1267-79. doi: 10.1093/gbe/evv062.

20.

WGS Analysis and Interpretation in Clinical and Public Health Microbiology Laboratories: What Are the Requirements and How Do Existing Tools Compare?

Wyres KL, Conway TC, Garg S, Queiroz C, Reumann M, Holt K, Rusu LI.

Pathogens. 2014 Jun 11;3(2):437-58. doi: 10.3390/pathogens3020437. Review.

21.

Spatio-temporal information and knowledge representation of disease incidence and respective intervention strategies.

Davis M, von Cavallar S, Wyres KL, Reumann M, Sepulveda MJ, Rogers P.

Stud Health Technol Inform. 2014;205:1173-7.

PMID:
25160374
22.

Streptococcus pneumoniae carriage prevalence in Nepal: evaluation of a method for delayed transport of samples from remote regions and implications for vaccine implementation.

Hanieh S, Hamaluba M, Kelly DF, Metz JA, Wyres KL, Fisher R, Pradhan R, Shakya D, Shrestha L, Shrestha A, Joshi A, Habens J, Maharjan BD, Thorson S, Bohler E, Yu LM, Kelly S, Plested E, John T, Werno AM, Adhikari N, Murdoch DR, Brueggemann AB, Pollard AJ.

PLoS One. 2014 Jun 6;9(6):e98739. doi: 10.1371/journal.pone.0098739. eCollection 2014.

23.

Evidence of antimicrobial resistance-conferring genetic elements among pneumococci isolated prior to 1974.

Wyres KL, van Tonder A, Lambertsen LM, Hakenbeck R, Parkhill J, Bentley SD, Brueggemann AB.

BMC Genomics. 2013 Jul 24;14:500. doi: 10.1186/1471-2164-14-500.

24.

Pneumococcal capsular switching: a historical perspective.

Wyres KL, Lambertsen LM, Croucher NJ, McGee L, von Gottberg A, Liñares J, Jacobs MR, Kristinsson KG, Beall BW, Klugman KP, Parkhill J, Hakenbeck R, Bentley SD, Brueggemann AB.

J Infect Dis. 2013 Feb 1;207(3):439-49. doi: 10.1093/infdis/jis703. Epub 2012 Nov 21. Erratum in: J Infect Dis. 2013 Oct 1;208(7):1187.

25.

The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success.

Wyres KL, Lambertsen LM, Croucher NJ, McGee L, von Gottberg A, Liñares J, Jacobs MR, Kristinsson KG, Beall BW, Klugman KP, Parkhill J, Hakenbeck R, Bentley SD, Brueggemann AB.

Genome Biol. 2012 Nov 16;13(11):R103. doi: 10.1186/gb-2012-13-11-r103.

26.

Environmental factors determining the epidemiology and population genetic structure of the Bacillus cereus group in the field.

Raymond B, Wyres KL, Sheppard SK, Ellis RJ, Bonsall MB.

PLoS Pathog. 2010 May 20;6(5):e1000905. doi: 10.1371/journal.ppat.1000905.

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