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Items: 1 to 50 of 712

1.

The Novel Bromodomain and Extraterminal Domain Inhibitor INCB054329 Induces Vulnerabilities in Myeloma Cells That Inform Rational Combination Strategies.

Stubbs MC, Burn TC, Sparks RB, Maduskuie T, Diamond S, Rupar M, Wen X, Volgina A, Zolotarjova N, Waeltz P, Favata M, Jalluri R, Liu H, Liu XM, Li J, Collins R, Falahatpisheh N, Polam P, DiMatteo D, Feldman P, Dostalik V, Thekkat P, Gardiner C, He X, Li Y, Covington M, Wynn R, Ruggeri B, Yeleswaram S, Xue C, Yao W, Combs AP, Huber R, Hollis G, Scherle P, Liu P.

Clin Cancer Res. 2018 Sep 11. pii: clincanres.0098.2018. doi: 10.1158/1078-0432.CCR-18-0098. [Epub ahead of print]

PMID:
30206163
2.

Molecular monitoring of adenovirus reactivation in faeces after haematopoietic stem-cell transplantation to predict systemic infection: a retrospective cohort study.

Hum RM, Deambrosis D, Lum SH, Davies E, Bonney D, Guiver M, Turner A, Wynn RF, Hiwarkar P.

Lancet Haematol. 2018 Sep;5(9):e422-e429. doi: 10.1016/S2352-3026(18)30130-3.

PMID:
30172346
3.

The importance of cultural awareness when planning and implementing telepsychiatric services.

Acharibasam JW, Wynn R.

Rural Remote Health. 2018 Aug;18(3):4724. doi: 10.22605/RRH4724. Epub 2018 Aug 24. No abstract available.

4.

Treatment dilemmas in asymptomatic children with primary haemophagocytic lymphohistiocytosis.

Lucchini G, Marsh R, Gilmour K, Worth A, Nademi Z, Rao A, Booth C, Amrolia P, Silva J, Chiesa R, Wynn R, Lehmberg K, Astigarraga I, Gungor T, Stary J, Moshous D, Ifversen M, Zinn D, Jordan M, Kumar A, Yasumi T, Veys P, Rao K.

Blood. 2018 Aug 13. pii: blood-2018-01-827485. doi: 10.1182/blood-2018-01-827485. [Epub ahead of print]

PMID:
30104219
5.

Social Media Use in Interventions for Diabetes: Rapid Evidence-Based Review.

Gabarron E, Årsand E, Wynn R.

J Med Internet Res. 2018 Aug 10;20(8):e10303. doi: 10.2196/10303. Review.

6.

Fully Automated Convolutional Neural Network Method for Quantification of Breast MRI Fibroglandular Tissue and Background Parenchymal Enhancement.

Ha R, Chang P, Mema E, Mutasa S, Karcich J, Wynn RT, Liu MZ, Jambawalikar S.

J Digit Imaging. 2018 Aug 3. doi: 10.1007/s10278-018-0114-7. [Epub ahead of print]

PMID:
30076489
7.

Binding Assays for Bromodomain Proteins: Their Utility in Drug Discovery in Oncology and Inflammatory Disease.

Zolotarjova NI, Wynn R.

Curr Protoc Pharmacol. 2018 Mar;80(1):3.16.1-3.16.14. doi: 10.1002/cpph.35.

PMID:
30040205
8.

Outcome of domino hematopoietic stem cell transplantation in human subjects: An international case series.

Belderbos ME, Gennery AR, Dvorak CC, Blok HJ, Eikema DJ, Silva JMF, Veys P, Neven B, Buckley R, Cole T, Cowan MJ, Goebel WS, Hoenig M, Kuo CY, Stiehm ER, Wynn R, Bierings M; Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation and the Primary Immune Deficiency Treatment Consortium.

J Allergy Clin Immunol. 2018 Jul 5. pii: S0091-6749(18)30993-X. doi: 10.1016/j.jaci.2018.06.030. [Epub ahead of print] No abstract available.

PMID:
29981805
9.

Evaluation of association between degree of background parenchymal enhancement on MRI and breast cancer subtype.

Ha R, Mango V, Al-Khalili R, Mema E, Friedlander L, Desperito E, Wynn RT.

Clin Imaging. 2018 Sep - Oct;51:307-310. doi: 10.1016/j.clinimag.2018.05.008. Epub 2018 May 5.

PMID:
29945057
10.

Preclinical characterization of INCB053914, a novel pan-PIM kinase inhibitor, alone and in combination with anticancer agents, in models of hematologic malignancies.

Koblish H, Li YL, Shin N, Hall L, Wang Q, Wang K, Covington M, Marando C, Bowman K, Boer J, Burke K, Wynn R, Margulis A, Reuther GW, Lambert QT, Dostalik Roman V, Zhang K, Feng H, Xue CB, Diamond S, Hollis G, Yeleswaram S, Yao W, Huber R, Vaddi K, Scherle P.

PLoS One. 2018 Jun 21;13(6):e0199108. doi: 10.1371/journal.pone.0199108. eCollection 2018.

11.

Clenched fist syndrome: a case report.

Nissen T, Wynn R.

J Med Case Rep. 2018 Jun 18;12(1):168. doi: 10.1186/s13256-018-1729-5.

12.

Are Mammographically Occult Additional Tumors Identified More Than 2 Cm Away From the Primary Breast Cancer on MRI Clinically Significant?

Goodman S, Mango V, Friedlander L, Desperito E, Wynn R, Ha R.

Acad Radiol. 2018 Jun 8. pii: S1076-6332(18)30248-4. doi: 10.1016/j.acra.2018.05.009. [Epub ahead of print]

PMID:
29891105
13.

Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency.

Nademi Z, Wynn RF, Slatter M, Hughes SM, Bonney D, Qasim W, Latour S, Trück J, Patel S, Abinun M, Flood T, Hambleton S, Cant AJ, Gennery AR, Arkwright PD.

Bone Marrow Transplant. 2018 Jun 8. doi: 10.1038/s41409-018-0246-x. [Epub ahead of print] No abstract available.

PMID:
29884857
14.

Social media for health promotion in diabetes: study protocol for a participatory public health intervention design.

Gabarron E, Bradway M, Fernandez-Luque L, Chomutare T, Hansen AH, Wynn R, Årsand E.

BMC Health Serv Res. 2018 Jun 5;18(1):414. doi: 10.1186/s12913-018-3178-7.

15.

The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.

White PJ, McGarrah RW, Grimsrud PA, Tso SC, Yang WH, Haldeman JM, Grenier-Larouche T, An J, Lapworth AL, Astapova I, Hannou SA, George T, Arlotto M, Olson LB, Lai M, Zhang GF, Ilkayeva O, Herman MA, Wynn RM, Chuang DT, Newgard CB.

Cell Metab. 2018 Jun 5;27(6):1281-1293.e7. doi: 10.1016/j.cmet.2018.04.015. Epub 2018 May 17.

PMID:
29779826
16.

Multicenter phase 1/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation.

Ip W, Silva JMF, Gaspar H, Mitra A, Patel S, Rao K, Chiesa R, Amrolia P, Gilmour K, Ahsan G, Slatter M, Gennery AR, Wynn RF, Veys P, Qasim W.

Cytotherapy. 2018 Jun;20(6):830-838. doi: 10.1016/j.jcyt.2018.03.040. Epub 2018 May 9.

PMID:
29753677
17.

A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity.

Wu CY, Satapati S, Gui W, Wynn RM, Sharma G, Lou M, Qi X, Burgess SC, Malloy C, Khemtong C, Sherry AD, Chuang DT, Merritt ME.

J Biol Chem. 2018 Jun 22;293(25):9604-9613. doi: 10.1074/jbc.RA118.002838. Epub 2018 May 8.

PMID:
29739849
18.

Refining the phenotype associated with biallelic DNAJC21 mutations.

D'Amours G, Lopes F, Gauthier J, Saillour V, Nassif C, Wynn R, Alos N, Leblanc T, Capri Y, Nizard S, Lemyre E, Michaud JL, Pelletier VA, Pastore YD, Soucy JF.

Clin Genet. 2018 Aug;94(2):252-258. doi: 10.1111/cge.13370. Epub 2018 Jun 7.

PMID:
29700810
19.

Axillary Lymph Node Evaluation Utilizing Convolutional Neural Networks Using MRI Dataset.

Ha R, Chang P, Karcich J, Mutasa S, Fardanesh R, Wynn RT, Liu MZ, Jambawalikar S.

J Digit Imaging. 2018 Apr 25. doi: 10.1007/s10278-018-0086-7. [Epub ahead of print]

PMID:
29696472
20.

Responsibilities with conflicting priorities: a qualitative study of ACT providers' experiences with community treatment orders.

Stuen HK, Landheim A, Rugkåsa J, Wynn R.

BMC Health Serv Res. 2018 Apr 18;18(1):290. doi: 10.1186/s12913-018-3097-7.

21.
22.

Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice.

Wu CY, Tso SC, Chuang JL, Gui WJ, Lou M, Sharma G, Khemtong C, Qi X, Wynn RM, Chuang DT.

Mol Metab. 2018 Jun;12:12-24. doi: 10.1016/j.molmet.2018.03.014. Epub 2018 Mar 31.

23.

Patterns and frequency of renal abnormalities in Fanconi anaemia: implications for long-term management.

Sathyanarayana V, Lee B, Wright NB, Santos R, Bonney D, Wynn R, Patel L, Chandler K, Cheesman E, Schindler D, Webb NJA, Meyer S.

Pediatr Nephrol. 2018 Sep;33(9):1547-1551. doi: 10.1007/s00467-018-3952-0. Epub 2018 Apr 12.

24.

The Impact of Interruptions on Chest Radiograph Interpretation: Effects on Reading Time and Accuracy.

Wynn RM, Howe JL, Kelahan LC, Fong A, Filice RW, Ratwani RM.

Acad Radiol. 2018 Mar 28. pii: S1076-6332(18)30129-6. doi: 10.1016/j.acra.2018.03.016. [Epub ahead of print]

PMID:
29605562
25.

Involuntary admission in Norwegian adult psychiatric hospitals: a systematic review.

Wynn R.

Int J Ment Health Syst. 2018 Mar 22;12:10. doi: 10.1186/s13033-018-0189-z. eCollection 2018. Review.

26.

High transplant-related mortality associated with haematopoietic stem cell transplantation for paediatric therapy-related acute myeloid leukaemia (t-AML). A study on behalf of the United Kingdom Paediatric Blood and Bone Marrow Transplant Group.

Gassas A, Sivaprakasam P, Cummins M, Breslin P, Patrick K, Slatter M, Skinner R, Shenton G, Gibson B, Lawson S, Petterson T, Potter M, James B, Hough R, Hiwarkar P, Vora A, Veys P, De La Fuente J, Wynn R, Amrolia P.

Bone Marrow Transplant. 2018 Sep;53(9):1165-1169. doi: 10.1038/s41409-018-0157-x. Epub 2018 Mar 15.

PMID:
29545594
27.

In the Setting of Negative Mammogram, Is Additional Breast Ultrasound Necessary for Evaluation of Breast Pain?

Mema E, Cho E, Ryu YK, Jadeja P, Wynn R, Taback B, Ha R.

Curr Probl Diagn Radiol. 2018 Jan 9. pii: S0363-0188(17)30215-3. doi: 10.1067/j.cpradiol.2017.12.007. [Epub ahead of print]

PMID:
29402490
28.
29.

The unusual suspects: A review of unusual benign and malignant male breast imaging cases.

Mango VL, Goodman S, Clarkin K, Wynn RT, Friedlander L, Hibshoosh H, Ha R.

Clin Imaging. 2018 Jul - Aug;50:78-85. doi: 10.1016/j.clinimag.2017.12.012. Epub 2017 Dec 28. Review.

PMID:
29328960
30.

Patients' and therapists' experiences with a new treatment programme for eating disorders that combines physical exercise and dietary therapy: the PED-t trial. A qualitative study protocol.

Pettersen G, Rosenvinge JH, Bakland M, Wynn R, Mathisen TF, Sundgot-Borgen J.

BMJ Open. 2018 Jan 8;8(1):e018708. doi: 10.1136/bmjopen-2017-018708.

31.

Quality of life of Hurler syndrome patients after successful hematopoietic stem cell transplantation.

Aldenhoven M, van den Broek BTA, Wynn RF, O'Meara A, Veys P, Rovelli A, Jones SA, Parini R, van Hasselt PM, Renard M, Bordon V, de Koning TJ, Boelens JJ.

Blood Adv. 2017 Nov 7;1(24):2236-2242. doi: 10.1182/bloodadvances.2017011387. eCollection 2017 Nov 14. Erratum in: Blood Adv. 2017 Dec 07;1(26):2535.

32.

Paediatric amendment to adult BSH Guidelines for aplastic anaemia.

Samarasinghe S, Veys P, Vora A, Wynn R.

Br J Haematol. 2018 Jan;180(2):201-205. doi: 10.1111/bjh.15066. Epub 2017 Dec 28. No abstract available.

PMID:
29285764
33.

Utilization of multiple SAVI SCOUT surgical guidance system reflectors in the same breast: A single-institution feasibility study.

Jadeja PH, Mango V, Patel S, Friedlander L, Desperito E, Ayala-Bustamante E, Wynn R, Chen-Seetoo M, Taback B, Feldman S, Ha R.

Breast J. 2018 Jul;24(4):531-534. doi: 10.1111/tbj.12979. Epub 2017 Dec 18.

PMID:
29251387
34.

The effect of haemopoietic stem cell transplantation on the ocular phenotype in mucopolysaccharidosis type I (Hurler).

Javed A, Aslam T, Jones SA, Mercer J, Tyler K, Church H, Ghosh A, Wynn R, Sornalingam K, Ashworth J.

Acta Ophthalmol. 2018 Aug;96(5):494-498. doi: 10.1111/aos.13627. Epub 2017 Dec 14.

PMID:
29240299
35.

Haematopoietic Stem Cell Transplantation Arrests the Progression of Neurodegenerative Disease in Late-Onset Tay-Sachs Disease.

Stepien KM, Lum SH, Wraith JE, Hendriksz CJ, Church HJ, Priestman D, Platt FM, Jones S, Jovanovic A, Wynn R.

JIMD Rep. 2018;41:17-23. doi: 10.1007/8904_2017_76. Epub 2017 Dec 7.

36.

SIFD as a novel cause of severe fetal hydrops and neonatal anaemia with iron loading and marked extramedullary haemopoiesis.

Barton C, Kausar S, Kerr D, Bitetti S, Wynn R.

J Clin Pathol. 2018 Mar;71(3):275-278. doi: 10.1136/jclinpath-2017-204698. Epub 2017 Oct 21.

37.

Results and conclusions of the European Intergroup EURO-LB02 trial in children and adolescents with lymphoblastic lymphoma.

Landmann E, Burkhardt B, Zimmermann M, Meyer U, Woessmann W, Klapper W, Wrobel G, Rosolen A, Pillon M, Escherich G, Attarbaschi A, Beishuizen A, Mellgren K, Wynn R, Ratei R, Plesa A, Schrappe M, Reiter A, Bergeron C, Patte C, Bertrand Y.

Haematologica. 2017 Dec;102(12):2086-2096. doi: 10.3324/haematol.2015.139162. Epub 2017 Oct 5.

38.

Identification of the ferredoxin interaction sites on ferredoxin-dependent glutamate synthase from Synechocystis sp. PCC 6803.

Hirasawa M, Solis J, Vaidyanathan N, Srivastava AP, Wynn RM, Sutton RB, Knaff DB.

Photosynth Res. 2017 Dec;134(3):317-328. doi: 10.1007/s11120-017-0446-z. Epub 2017 Oct 3.

PMID:
28975508
39.

How mental health service systems are organized may affect the rate of acute admissions to specialized care: Report from a natural experiment involving 5338 admissions.

Myklebust LH, Sørgaard K, Wynn R.

SAGE Open Med. 2017 Aug 3;5:2050312117724311. doi: 10.1177/2050312117724311. eCollection 2017.

40.

Clinical implementation and evaluation of the Acuros dose calculation algorithm.

Yan C, Combine AG, Bednarz G, Lalonde RJ, Hu B, Dickens K, Wynn R, Pavord DC, Saiful Huq M.

J Appl Clin Med Phys. 2017 Sep;18(5):195-209. doi: 10.1002/acm2.12149. Epub 2017 Aug 20.

41.

Reflector-guided breast tumor localization versus wire localization for lumpectomies: A comparison of surgical outcomes.

Patel SN, Mango VL, Jadeja P, Friedlander L, Desperito E, Wynn R, Feldman S, Ha R.

Clin Imaging. 2018 Jan - Feb;47:14-17. doi: 10.1016/j.clinimag.2017.07.020. Epub 2017 Aug 1.

PMID:
28818762
42.

Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in pediatric patients: a new classification from the European society for blood and marrow transplantation.

Corbacioglu S, Carreras E, Ansari M, Balduzzi A, Cesaro S, Dalle JH, Dignan F, Gibson B, Guengoer T, Gruhn B, Lankester A, Locatelli F, Pagliuca A, Peters C, Richardson PG, Schulz AS, Sedlacek P, Stein J, Sykora KW, Toporski J, Trigoso E, Vetteranta K, Wachowiak J, Wallhult E, Wynn R, Yaniv I, Yesilipek A, Mohty M, Bader P.

Bone Marrow Transplant. 2018 Feb;53(2):138-145. doi: 10.1038/bmt.2017.161. Epub 2017 Jul 31.

43.

Does breast MRI background parenchymal enhancement indicate metabolic activity? Qualitative and 3D quantitative computer imaging analysis.

Mema E, Mango VL, Guo X, Karcich J, Yeh R, Wynn RT, Zhao B, Ha RS.

J Magn Reson Imaging. 2018 Mar;47(3):753-759. doi: 10.1002/jmri.25798. Epub 2017 Jun 24.

PMID:
28646614
44.

Allele-level HLA matching for umbilical cord blood transplantation for non-malignant diseases in children: a retrospective analysis.

Eapen M, Wang T, Veys PA, Boelens JJ, St Martin A, Spellman S, Bonfim CS, Brady C, Cant AJ, Dalle JH, Davies SM, Freeman J, Hsu KC, Fleischhauer K, Kenzey C, Kurtzberg J, Michel G, Orchard PJ, Paviglianiti A, Rocha V, Veneris MR, Volt F, Wynn R, Lee SJ, Horowitz MM, Gluckman E, Ruggeri A.

Lancet Haematol. 2017 Jul;4(7):e325-e333. doi: 10.1016/S2352-3026(17)30104-7. Epub 2017 Jun 13.

45.

INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology.

Yue EW, Sparks R, Polam P, Modi D, Douty B, Wayland B, Glass B, Takvorian A, Glenn J, Zhu W, Bower M, Liu X, Leffet L, Wang Q, Bowman KJ, Hansbury MJ, Wei M, Li Y, Wynn R, Burn TC, Koblish HK, Fridman JS, Emm T, Scherle PA, Metcalf B, Combs AP.

ACS Med Chem Lett. 2017 Mar 6;8(5):486-491. doi: 10.1021/acsmedchemlett.6b00391. eCollection 2017 May 11.

46.

The PED-t trial protocol: The effect of physical exercise -and dietary therapy compared with cognitive behavior therapy in treatment of bulimia nervosa and binge eating disorder.

Mathisen TF, Rosenvinge JH, Pettersen G, Friborg O, Vrabel K, Bratland-Sanda S, Svendsen M, Stensrud T, Bakland M, Wynn R, Sundgot-Borgen J.

BMC Psychiatry. 2017 May 12;17(1):180. doi: 10.1186/s12888-017-1312-4.

47.

Beyond Wires and Seeds: Reflector-guided Breast Lesion Localization and Excision.

Mango VL, Wynn RT, Feldman S, Friedlander L, Desperito E, Patel SN, Gomberawalla A, Ha R.

Radiology. 2017 Aug;284(2):365-371. doi: 10.1148/radiol.2017161661. Epub 2017 Apr 21.

PMID:
28430555
48.

Long term survival and cardiopulmonary outcome in children with Hurler syndrome after haematopoietic stem cell transplantation.

Lum SH, Stepien KM, Ghosh A, Broomfield A, Church H, Mercer J, Jones S, Wynn R.

J Inherit Metab Dis. 2017 May;40(3):455-460. doi: 10.1007/s10545-017-0034-6. Epub 2017 Mar 10.

PMID:
28283844
49.

Ascitic fluid drainage using a peritoneal dialysis catheter to prevent and treat multi-organ dysfunction in veno-occlusive disease in children undergoing hematopoietic stem cell transplantation.

Parmar V, Lewis M, Shenoy M, Bonney D, Wynn R.

Pediatr Blood Cancer. 2017 Sep;64(9). doi: 10.1002/pbc.26469. Epub 2017 Feb 28.

PMID:
28244636
50.

Allogeneic stem cell transplantation for refractory acute myeloid leukemia in pediatric patients: the UK experience.

O'Hare P, Lucchini G, Cummins M, Veys P, Potter M, Lawson S, Vora A, Wynn R, Peniket A, Kirkland K, Pearce R, Perry J, Amrolia PJ.

Bone Marrow Transplant. 2017 Jun;52(6):825-831. doi: 10.1038/bmt.2017.3. Epub 2017 Feb 20.

PMID:
28218757

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