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Items: 32

1.

Characterization of bropirimine O-glucuronidation in human liver microsomes.

Wynalda MA, Wynalda KM, Amore BM, Fagerness PE, Wienkers LC.

Xenobiotica. 2003 Oct;33(10):999-1011.

PMID:
14555337
2.

Effect of carbonate anion on cytochrome P450 2D6-mediated metabolism in vitro: the potential role of multiple oxygenating species.

Hutzler JM, Powers FJ, Wynalda MA, Wienkers LC.

Arch Biochem Biophys. 2003 Sep 15;417(2):165-75.

PMID:
12941298
3.

In vitro metabolism of clindamycin in human liver and intestinal microsomes.

Wynalda MA, Hutzler JM, Koets MD, Podoll T, Wienkers LC.

Drug Metab Dispos. 2003 Jul;31(7):878-87.

PMID:
12814964
4.

Identification of phenylisoxazolines as novel and viable antibacterial agents active against Gram-positive pathogens.

Barbachyn MR, Cleek GJ, Dolak LA, Garmon SA, Morris J, Seest EP, Thomas RC, Toops DS, Watt W, Wishka DG, Ford CW, Zurenko GE, Hamel JC, Schaadt RD, Stapert D, Yagi BH, Adams WJ, Friis JM, Slatter JG, Sams JP, Oien NL, Zaya MJ, Wienkers LC, Wynalda MA.

J Med Chem. 2003 Jan 16;46(2):284-302.

PMID:
12519066
6.

Oxidation of the novel oxazolidinone antibiotic linezolid in human liver microsomes.

Wynalda MA, Hauer MJ, Wienkers LC.

Drug Metab Dispos. 2000 Sep;28(9):1014-7.

PMID:
10950842
7.

Cytochrome P-450-mediated metabolism of the individual enantiomers of the antidepressant agent reboxetine in human liver microsomes.

Wienkers LC, Allievi C, Hauer MJ, Wynalda MA.

Drug Metab Dispos. 1999 Nov;27(11):1334-40.

PMID:
10534319
8.

Human biotransformation of bropirimine. Characterization of the major bropirimine oxidative metabolites formed in vitro.

Wynalda MA, Hauer MJ, Wienkers LC.

Drug Metab Dispos. 1998 Oct;26(10):1048-51.

PMID:
9763414
10.
11.

Reversible, hepatic, lysosomal phospholipidosis in rat induced by subchronic daily administration of trospectomycin sulfate.

Cox JW, Ulrich RG, Wynalda MA, McKenna R, Larsen ER, Ginsberg LC, Epps DE.

Biochem Pharmacol. 1989 Oct 15;38(20):3535-41.

PMID:
2530987
12.

Pharmacokinetics and excretion of the 21-aminosteroid antioxidant U-74006F in rat and perfused rat liver.

Cox JW, Larson PG, Wynalda MA, Sood VK, Verburg MT, Pullen RN.

Drug Metab Dispos. 1989 Jul-Aug;17(4):373-9.

PMID:
2571475
13.

Development and comparative evaluation of radioimmunoassay and gas chromatographic/mass spectrometric procedures for determination of leukotriene B4.

Mathews WR, Bundy GL, Wynalda MA, Guido DM, Schneider WP, Fitzpatrick FA.

Anal Chem. 1988 Feb 15;60(4):349-53. No abstract available.

PMID:
2833859
14.

Human neutrophil activation with interleukin-1. A role for intracellular calcium and arachidonic acid lipoxygenation.

Smith RJ, Epps DE, Justen JM, Sam LM, Wynalda MA, Fitzpatrick FA, Yein FS.

Biochem Pharmacol. 1987 Nov 15;36(22):3851-8.

PMID:
2825706
15.

Arachidonic acid and 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid modulate human polymorphonuclear neutrophil activation by monocyte derived neutrophil activating factor.

Smith RJ, Sam LM, Justen JM, Bundy GL, Fitzpatrick FA, Wynalda MA.

Biochem Biophys Res Commun. 1987 Oct 29;148(2):636-45.

PMID:
2825667
16.

Inhibition of cyclooxygenase activity and platelet aggregation by epoxyeicosatrienoic acids. Influence of stereochemistry.

Fitzpatrick FA, Ennis MD, Baze ME, Wynalda MA, McGee JE, Liggett WF.

J Biol Chem. 1986 Nov 15;261(32):15334-8.

17.

Plasma levels of the prodrug, arbaprostil, [(15R)-15-methylprostaglandin E2], and its active, antiulcer (15S) epimer in humans after single dose oral administration.

Cox JW, Bothwell WM, Pullen RH, Wynalda MA, Fitzpatrick FA, VanderLugt JT.

J Pharm Sci. 1986 Nov;75(11):1107-12.

PMID:
3820107
18.

Determination of leukotriene C4 by radioimmunoassay with a specific antiserum against a synthetic hapten.

Fitzpatrick FA, Wynalda MA, Morton DR, Pike JE.

Adv Prostaglandin Thromboxane Leukot Res. 1985;15:29-31. No abstract available.

PMID:
2936108
19.

Determination of leukotriene C4 by radioimmunoassay with a specific antiserum generated from a synthetic hapten mimic.

Wynalda MA, Brashler JR, Bach MK, Morton DR, Fitzpatrick FA.

Anal Chem. 1984 Sep;56(11):1862-5. No abstract available.

PMID:
6496955
20.

Albumin-eicosanoid interactions. A model system to determine their attributes and inhibition.

Fitzpatrick FA, Liggett WF, Wynalda MA.

J Biol Chem. 1984 Mar 10;259(5):2722-7.

21.

Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro.

Fitzpatrick FA, Wynalda MA.

J Biol Chem. 1983 Oct 10;258(19):11713-8.

23.

Albumin stabilizes leukotriene A4.

Fitzpatrick FA, Morton DR, Wynalda MA.

J Biol Chem. 1982 May 10;257(9):4680-3.

24.

Comparison between circulating interferon and drug levels following administration of 2-amino-5-bromo-6-phenyl-4(3H)-pyrimidinone (ABPP) to different animal species.

Hamilton RD, Wynalda MA, Fitzpatrick FA, Teagarden DL, Hamdy AH, Snider BG, Weed SD, Stringfellow DA.

J Interferon Res. 1982;2(3):317-27.

PMID:
6182250
25.

Albumins stabilize prostaglandin I2.

Wynalda MA, Fitzpatrick FA.

Prostaglandins. 1980 Nov;20(5):853-61.

PMID:
7008091
26.

High-performance liquid chromatographic determination of 5-halopyrimidinone interferon inducers.

Wynalda MA, Fitzpatrick FA.

Anal Chem. 1980 Oct;52(12):1931-4. No abstract available.

PMID:
7435991
27.

High-performance liquid chromatographic assay for prostacyclin.

Wynalda MA, Lincoln FH, Fitzpatrick FA.

J Chromatogr. 1979 Sep 1;176(3):413-7. No abstract available.

PMID:
397947
28.

A radioimmunoassay for thromboxane B2.

Fitzpatrick FA, Gorman RR, Mc Guire JC, Kelly RC, Wynalda MA, Sun FF.

Anal Biochem. 1977 Sep;82(1):1-7. No abstract available.

PMID:
907115
29.

Oximes for high performance liquid and electron capture gas chromatography of prostaglandins and thromboxanes.

Fitzpatrick FA, Wynalda MA, Kaiser DG.

Anal Chem. 1977 Jun;49(7):1032-5. No abstract available.

PMID:
860828
30.

Electron capture gas chromatographic detection of thromboxane B2.

Fitzpatrick FA, Gorman RR, Wynalda MA.

Prostaglandins. 1977 Feb;13(2):201-8.

PMID:
847227
31.

In vivo suppression of prostaglandin biosynthesis by non-steroidal anti-inflammatory agents.

Fitzpatrick FA, Wynalda MA.

Prostaglandins. 1976 Dec;12(6):1037-51.

PMID:
1005736
32.

A rapid, solid phase radioimmunoassay for prostaglandin F2alpha and its main circulating metabolite.

Fitzpatrick FA, Wynalda MA.

Anal Biochem. 1976 May 21;73(1):198-208. No abstract available.

PMID:
942096

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