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Items: 1 to 50 of 115

1.

Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer's Disease.

Borroni E, Bohrmann B, Grueninger F, Prinssen E, Nave S, Loetscher H, Chinta SJ, Rajagopalan S, Rane A, Siddiqui A, Ellenbroek B, Messer J, Pähler A, Andersen JK, Wyler R, Cesura AM.

J Pharmacol Exp Ther. 2017 Sep;362(3):413-423. doi: 10.1124/jpet.117.241653. Epub 2017 Jun 22.

PMID:
28642233
2.

The subchronic phencyclidine rat model: relevance for the assessment of novel therapeutics for cognitive impairment associated with schizophrenia.

Janhunen SK, Svärd H, Talpos J, Kumar G, Steckler T, Plath N, Lerdrup L, Ruby T, Haman M, Wyler R, Ballard TM.

Psychopharmacology (Berl). 2015 Nov;232(21-22):4059-83. doi: 10.1007/s00213-015-3954-6. Epub 2015 Jun 14. Review.

PMID:
26070547
3.

1-Benzyloxy-4,5-dihydro-1H-imidazol-2-yl-amines, a novel class of NR1/2B subtype selective NMDA receptor antagonists.

Alanine A, Bourson A, Büttelmann B, Gill R, Heitz MP, Mutel V, Pinard E, Trube G, Wyler R.

Bioorg Med Chem Lett. 2003 Oct 6;13(19):3155-9.

PMID:
12951084
4.

4-(3,4-dihydro-1H-isoquinolin-2yl)-pyridines and 4-(3,4-dihydro-1H-isoquinolin-2-yl)-quinolines as potent NR1/2B subtype selective NMDA receptor antagonists.

Büttelmann B, Alanine A, Bourson A, Gill R, Heitz MP, Mutel V, Pinard E, Trube G, Wyler R.

Bioorg Med Chem Lett. 2003 May 19;13(10):1759-62.

PMID:
12729659
5.

Reversal of a vigilance decrement in the aged rat by subtype-selective nicotinic ligands.

Grottick AJ, Haman M, Wyler R, Higgins GA.

Neuropsychopharmacology. 2003 May;28(5):880-7. Epub 2003 Mar 5.

6.

2-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines as a novel class of NR1/2B subtype selective NMDA receptor antagonists.

Büttelmann B, Alanine A, Bourson A, Gill R, Heitz MP, Mutel V, Pinard E, Trube G, Wyler R.

Bioorg Med Chem Lett. 2003 Mar 10;13(5):829-32.

PMID:
12617901
7.

Pharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist.

Gill R, Alanine A, Bourson A, Buttelmann B, Fischer G, Heitz MP, Kew JN, Levet-Trafit B, Lorez HP, Malherbe P, Miss MT, Mutel V, Pinard E, Roever S, Schmitt M, Trube G, Wybrecht R, Wyler R, Kemp JA.

J Pharmacol Exp Ther. 2002 Sep;302(3):940-8.

PMID:
12183650
8.

4-Aminoquinolines as a novel class of NR1/2B subtype selective NMDA receptor antagonists.

Pinard E, Alanine A, Bourson A, Büttelmann B, Heitz M, Mutela Ramanjit Gill V, Trube G, Wyler R.

Bioorg Med Chem Lett. 2002 Sep 16;12(18):2615-9.

PMID:
12182873
9.

A study of the nicotinic agonist SIB-1553A on locomotion and attention as measured by the five-choice serial reaction time task.

Grottick AJ, Wyler R, Higgins GA.

Pharmacol Biochem Behav. 2001 Dec;70(4):505-13.

PMID:
11796150
10.

Discovery of (R)-1-[2-hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol: a novel NR1/2B subtype selective NMDA receptor antagonist.

Pinard E, Alanine A, Bourson A, Büttelmann B, Gill R, Heitz M, Jaeschke G, Mutel V, Trube G, Wyler R.

Bioorg Med Chem Lett. 2001 Aug 20;11(16):2173-6.

PMID:
11514163
11.

Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine.

Grottick AJ, Trube G, Corrigall WA, Huwyler J, Malherbe P, Wyler R, Higgins GA.

J Pharmacol Exp Ther. 2000 Sep;294(3):1112-9.

PMID:
10945867
12.
13.

Pharmacologic evaluation of the discriminative stimulus of metachlorophenylpiperazine.

Bourson A, Wanner D, Wyler R, Petit N, Zwingelstein C, Rudler A, Sleight AJ.

Pharmacol Biochem Behav. 1996 Jan;53(1):107-14.

PMID:
8848438
14.

Encapsulation of methane and other small molecules in a self-assembling superstructure.

Branda N, Wyler R, Rebek J Jr.

Science. 1994 Mar 4;263(5151):1267-8.

PMID:
8122107
15.
17.

Propagation of the virus of porcine epidemic diarrhea in cell culture.

Hofmann M, Wyler R.

J Clin Microbiol. 1988 Nov;26(11):2235-9.

18.

[The inactivation of viruses in sewage sludge treatment].

Traub F, Spillmann SK, Schwyzer M, Wyler R.

Schriftenr Ver Wasser Boden Lufthyg. 1988;78:107-19. German. No abstract available.

PMID:
2854912
19.

Murine glia cells in culture can be stimulated to generate reactive oxygen.

Sonderer B, Wild P, Wyler R, Fontana A, Peterhans E, Schwyzer M.

J Leukoc Biol. 1987 Nov;42(5):463-73.

PMID:
2824645
20.
21.

Inactivation of animal viruses during sewage sludge treatment.

Spillmann SK, Traub F, Schwyzer M, Wyler R.

Appl Environ Microbiol. 1987 Sep;53(9):2077-81.

22.

[Serologic study of the occurrence of epizootic viral diarrhea in swine in Switzerland].

Hofmann M, Wyler R.

Schweiz Arch Tierheilkd. 1987 Aug;129(8):437-42. German. No abstract available.

PMID:
2821613
23.

A synthesis of N-acetylneuraminic acid and [6-2H]-N-acetylneuraminic acid from N-acetyl-D-glucosamine.

Julina R, Müller I, Vasella A, Wyler R.

Carbohydr Res. 1987 Jul 1;164:415-32.

PMID:
3621240
24.

The genome of caprine herpesvirus 1: genome structure and relatedness to bovine herpesvirus 1.

Engels M, Loepfe E, Wild P, Schraner E, Wyler R.

J Gen Virol. 1987 Jul;68 ( Pt 7):2019-23.

PMID:
3037021
26.

Method for determining virus inactivation during sludge treatment processes.

Traub F, Spillmann SK, Wyler R.

Appl Environ Microbiol. 1986 Sep;52(3):498-503.

27.

[Prevalence of bovine herpesvirus 4 in the Swiss cattle population and possible serologic cross reaction with bovine herpesvirus 1 (IBR/IPV virus)].

Metzler AE, Wyler R.

Schweiz Arch Tierheilkd. 1986 Sep;128(9):459-67. German. No abstract available.

PMID:
3022374
28.

High rate of insufficient antibody titers after single-day immunization with human diploid-cell-strain vaccine against rabies.

Täuber MG, Putzi R, Fuchs P, Wyler R, Lüthy R.

Klin Wochenschr. 1986 Jun 2;64(11):518-21.

PMID:
3723999
29.

[Reactivation of a latent bovine herpes mamillitis virus (BHV-2) infection in an animal with questionable IBR serology].

Hofmann M, Engels M, Metzler AE, Wyler R.

Schweiz Arch Tierheilkd. 1986 Jun;128(6):289-97. German. No abstract available.

PMID:
3018921
30.

Infections of calves with antigenic variants of bovine herpesvirus 1 (BHV-1) and neurological disease.

Schudel AA, Carrillo BJ, Wyler R, Metzler AE.

Zentralbl Veterinarmed B. 1986 May;33(4):303-10. No abstract available.

PMID:
2428188
31.

[Serologic overview study of the transmission of bovine coronavirus in Switzerland].

Battaglia M, Lutz H, Wyler R.

Schweiz Arch Tierheilkd. 1986 Apr;128(4):213-8. German. No abstract available.

PMID:
3012773
32.
33.

[Excretion of IBR virus, especially in milk, in experimentally infected cows].

Probst U, Wyler R, Kihm U, Ackermann M, Bruckner L, Müller HK, Ehrensperger F.

Schweiz Arch Tierheilkd. 1985 Nov;127(11):723-33. German. No abstract available.

PMID:
3003895
34.

[Bovine respiratory syncytial virus as a pathogen in the respiratory tract diseases of cattle: a clinical and seroepidemiologic study in Switzerland].

Linggi T, Wyler R.

Schweiz Arch Tierheilkd. 1985 Oct;127(10):651-9. German. No abstract available.

PMID:
4071019
35.

A chemiluminescent assay for mycoplasmas in cell cultures.

Bertoni G, Keist R, Groscurth P, Wyler R, Nicolet J, Peterhans E.

J Immunol Methods. 1985 Apr 8;78(1):123-33.

PMID:
3981014
36.

[Seroepidemiologic study of the occurrence of enzootic bovine leukosis in Switzerland using agar gel immunodiffusion and ELISA in blood and milk serum].

Vincenz E, Wyler R.

Schweiz Arch Tierheilkd. 1985 Mar;127(3):185-203. German. No abstract available.

PMID:
2986284
37.
38.

Analysis of parapoxvirus genomes.

Gassmann U, Wyler R, Wittek R.

Arch Virol. 1985;83(1-2):17-31.

PMID:
2982348
39.

[Occurrence of porcine parvovirus infection in Switzerland and a new method of virus demonstration using immune electron microscopy].

Zanoni RG, Henn V, Rutishauser UP, Wyler R.

Zentralbl Veterinarmed B. 1984 Dec;31(10):729-42. German. No abstract available.

PMID:
6098102
40.

[Incidence of virus isolation in fecal samples of swine with diarrhea including steatorrhea].

Rutishauser UP, Metzler AE, Corboz L, Wyler R.

Schweiz Arch Tierheilkd. 1984 Sep;126(9):453-66. German. No abstract available.

PMID:
6436972
41.

[Short review of the literature on viruses demonstrated in the digestive tract of swine].

Rutishauser UP, Wyler R.

Schweiz Arch Tierheilkd. 1984 Sep;126(9):447-52. Review. German. No abstract available.

PMID:
6436971
42.

[Tick-borne encephalitis in Switzerland. 2. Diagnosis and immunization].

Wyler R, Matile H.

Schweiz Rundsch Med Prax. 1984 May 8;73(19):613-7. German. No abstract available.

PMID:
6729326
43.

[Tick-borne encephalitis in Switzerland. 1. Clinical course and epidemiology].

Wyler R, Matile H.

Schweiz Rundsch Med Prax. 1984 May 8;73(19):601-12. German. No abstract available.

PMID:
6729325
44.

Induction of chemiluminescence during interaction of tumoricidal effector cell populations and tumor cells is dependent on the presence of mycoplasma.

Köppel P, Peterhans E, Bertoni G, Keist R, Groscurth P, Wyler R, Keller R.

J Immunol. 1984 Apr;132(4):2021-9.

PMID:
6607953
45.

Antibody-free target cells stimulate chemiluminescence in polymorphonuclear leukocytes: an artifact due to mycoplasma contamination.

Peterhans E, Bertoni G, Köppel P, Wyler R, Keller R.

Eur J Immunol. 1984 Feb;14(2):201-3.

PMID:
6421603
46.
47.

[1st cured case of bovine herpes mamillitis in Switzerland].

Müller R, Engels M, Metzler AE, Boller H, Wyler R.

Tierarztl Prax. 1984;12(3):297-305. German.

PMID:
6093283
48.

[Caprine herpesvirus in Switzerland: distribution, incidence and latency of infection].

Plebani GF, Engels M, Metzler AE, Wyler R.

Schweiz Arch Tierheilkd. 1983 Jul;125(7):395-411. German. No abstract available.

PMID:
6312558
49.

[Tick-borne encephalitis in a goat in lower Prätigau].

Zindel W, Wyler R.

Schweiz Arch Tierheilkd. 1983 Jun;125(6):383-6. German. No abstract available.

PMID:
6612291
50.

The chemiluminescent response of bovine polymorphonuclear leucocytes isolated from milk and blood.

Weber L, Peterhans E, Wyler R.

Vet Immunol Immunopathol. 1983 Apr;4(3):397-412.

PMID:
6868337

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