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Items: 12


Semiology, clustering, periodicity and natural history of seizures in an experimental occipital cortical epilepsy model.

Chang BL, Leite M, Snowball A, Lieb A, Chabrol E, Walker MC, Kullmann DM, Schorge S, Wykes RC.

Dis Model Mech. 2018 Dec 14;11(12). pii: dmm036194. doi: 10.1242/dmm.036194.


The Enlightened Brain: Novel Imaging Methods Focus on Epileptic Networks at Multiple Scales.

Rossi LF, Kullmann DM, Wykes RC.

Front Cell Neurosci. 2018 Mar 26;12:82. doi: 10.3389/fncel.2018.00082. eCollection 2018.


Seizures and disturbed brain potassium dynamics in the leukodystrophy megalencephalic leukoencephalopathy with subcortical cysts.

Dubey M, Brouwers E, Hamilton EMC, Stiedl O, Bugiani M, Koch H, Kole MHP, Boschert U, Wykes RC, Mansvelder HD, van der Knaap MS, Min R.

Ann Neurol. 2018 Mar;83(3):636-649. doi: 10.1002/ana.25190. Epub 2018 Mar 13.


Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity.

Rossi LF, Wykes RC, Kullmann DM, Carandini M.

Nat Commun. 2017 Aug 9;8(1):217. doi: 10.1038/s41467-017-00159-6.


Gene therapy and editing: Novel potential treatments for neuronal channelopathies.

Wykes RC, Lignani G.

Neuropharmacology. 2018 Apr;132:108-117. doi: 10.1016/j.neuropharm.2017.05.029. Epub 2017 May 28. Review.


Optogenetic approaches to treat epilepsy.

Wykes RC, Kullmann DM, Pavlov I, Magloire V.

J Neurosci Methods. 2016 Feb 15;260:215-20. doi: 10.1016/j.jneumeth.2015.06.004. Epub 2015 Jun 10. Review.


Gene therapy in epilepsy-is it time for clinical trials?

Kullmann DM, Schorge S, Walker MC, Wykes RC.

Nat Rev Neurol. 2014 May;10(5):300-4. doi: 10.1038/nrneurol.2014.43. Epub 2014 Mar 18. Review.


Gene therapy in status epilepticus.

Walker MC, Schorge S, Kullmann DM, Wykes RC, Heeroma JH, Mantoan L.

Epilepsia. 2013 Sep;54 Suppl 6:43-5. doi: 10.1111/epi.12275. Review.


Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy.

Wykes RC, Heeroma JH, Mantoan L, Zheng K, MacDonald DC, Deisseroth K, Hashemi KS, Walker MC, Schorge S, Kullmann DM.

Sci Transl Med. 2012 Nov 21;4(161):161ra152. doi: 10.1126/scitranslmed.3004190. Epub 2012 Nov 12.


Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells.

Wareham K, Vial C, Wykes RC, Bradding P, Seward EP.

Br J Pharmacol. 2009 Aug;157(7):1215-24. doi: 10.1111/j.1476-5381.2009.00287.x. Epub 2009 Jun 22.


Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival.

Wykes RC, Lee M, Duffy SM, Yang W, Seward EP, Bradding P.

J Immunol. 2007 Sep 15;179(6):4045-52.

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