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Items: 32


PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function.

Echeverri Tirado LC, Ghonim MA, Wang J, Al-Khami AA, Wyczechowska D, Luu HH, Kim H, Sanchez-Pino MD, Yélamos J, Yassin LM, Boulares AH.

Mediators Inflamm. 2019 Apr 24;2019:1656484. doi: 10.1155/2019/1656484. eCollection 2019.


Chemically Modified Variants of Fenofibrate with Antiglioblastoma Potential.

Stalinska J, Zimolag E, Pianovich NA, Zapata A, Lassak A, Rak M, Dean M, Ucar-Bilyeu D, Wyczechowska D, Culicchia F, Marrero L, Del Valle L, Sarkaria J, Peruzzi F, Jursic BS, Reiss K.

Transl Oncol. 2019 Jul;12(7):895-907. doi: 10.1016/j.tranon.2019.04.006. Epub 2019 May 9.


Microparticles in systemic sclerosis: Potential pro-inflammatory mediators and pulmonary hypertension biomarkers.

Lammi MR, Saketkoo LA, Okpechi SC, Ghonim MA, Wyczechowska D, Bauer N, Pyakurel K, Saito S, deBoisblanc BP, Boulares AH.

Respirology. 2019 Jul;24(7):675-683. doi: 10.1111/resp.13500. Epub 2019 Feb 12.


Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways.

Hossain F, Sorrentino C, Ucar DA, Peng Y, Matossian M, Wyczechowska D, Crabtree J, Zabaleta J, Morello S, Del Valle L, Burow M, Collins-Burow B, Pannuti A, Minter LM, Golde TE, Osborne BA, Miele L.

Front Oncol. 2018 Dec 4;8:575. doi: 10.3389/fonc.2018.00575. eCollection 2018.


Molecular and Structural Traits of Insulin Receptor Substrate 1/LC3 Nuclear Structures and Their Role in Autophagy Control and Tumor Cell Survival.

Lassak A, Dean M, Wyczechowska D, Wilk A, Marrero L, Trillo-Tinoco J, Boulares AH, Sarkaria JN, Del Valle L, Peruzzi F, Ochoa A, Reiss K.

Mol Cell Biol. 2018 Apr 30;38(10). pii: e00608-17. doi: 10.1128/MCB.00608-17. Print 2018 May 15.


A miRNA Signature for Cognitive Deficits and Alcohol Use Disorder in Persons Living with HIV/AIDS.

Wyczechowska D, Lin HY, LaPlante A, Jeansonne D, Lassak A, Parsons CH, Molina PE, Peruzzi F.

Front Mol Neurosci. 2017 Nov 15;10:385. doi: 10.3389/fnmol.2017.00385. eCollection 2017.


Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells.

Al-Khami AA, Zheng L, Del Valle L, Hossain F, Wyczechowska D, Zabaleta J, Sanchez MD, Dean MJ, Rodriguez PC, Ochoa AC.

Oncoimmunology. 2017 Jun 30;6(10):e1344804. doi: 10.1080/2162402X.2017.1344804. eCollection 2017.


Fuelling the mechanisms of asthma: Increased fatty acid oxidation in inflammatory immune cells may represent a novel therapeutic target.

Al-Khami AA, Ghonim MA, Del Valle L, Ibba SV, Zheng L, Pyakurel K, Okpechi SC, Garay J, Wyczechowska D, Sanchez-Pino MD, Rodriguez PC, Boulares AH, Ochoa AC.

Clin Exp Allergy. 2017 Sep;47(9):1170-1184. doi: 10.1111/cea.12947. Epub 2017 Jul 5.


T cells conditioned with MDSC show an increased anti-tumor activity after adoptive T cell based immunotherapy.

Raber PL, Sierra RA, Thevenot PT, Shuzhong Z, Wyczechowska DD, Kumai T, Celis E, Rodriguez PC.

Oncotarget. 2016 Apr 5;7(14):17565-78. doi: 10.18632/oncotarget.8197.


PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice.

Ghonim MA, Pyakurel K, Ibba SV, Wang J, Rodriguez P, Al-Khami AA, Lammi MR, Kim H, Zea AH, Davis C, Okpechi S, Wyczechowska D, Al-Ghareeb K, Mansy MS, Ochoa A, Naura AS, Boulares AH.

Clin Sci (Lond). 2015 Dec;129(11):951-62. doi: 10.1042/CS20150122. Epub 2015 Jul 23.


Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies.

Hossain F, Al-Khami AA, Wyczechowska D, Hernandez C, Zheng L, Reiss K, Valle LD, Trillo-Tinoco J, Maj T, Zou W, Rodriguez PC, Ochoa AC.

Cancer Immunol Res. 2015 Nov;3(11):1236-47. doi: 10.1158/2326-6066.CIR-15-0036. Epub 2015 May 29.


Fenofibrate subcellular distribution as a rationale for the intracranial delivery through biodegradable carrier.

Grabacka M, Waligorski P, Zapata A, Blake DA, Wyczechowska D, Wilk A, Rutkowska M, Vashistha H, Ayyala R, Ponnusamy T, John VT, Culicchia F, Wisniewska-Becker A, Reiss K.

J Physiol Pharmacol. 2015 Apr;66(2):233-47.


Anti-tumoral effects of miR-3189-3p in glioblastoma.

Jeansonne D, DeLuca M, Marrero L, Lassak A, Pacifici M, Wyczechowska D, Wilk A, Reiss K, Peruzzi F.

J Biol Chem. 2015 Mar 27;290(13):8067-80. doi: 10.1074/jbc.M114.633081. Epub 2015 Feb 2.


l-Arginine depletion blunts antitumor T-cell responses by inducing myeloid-derived suppressor cells.

Fletcher M, Ramirez ME, Sierra RA, Raber P, Thevenot P, Al-Khami AA, Sanchez-Pino D, Hernandez C, Wyczechowska DD, Ochoa AC, Rodriguez PC.

Cancer Res. 2015 Jan 15;75(2):275-83. doi: 10.1158/0008-5472.CAN-14-1491. Epub 2014 Nov 18.


Therapeutic efficacy of aldoxorubicin in an intracranial xenograft mouse model of human glioblastoma.

Marrero L, Wyczechowska D, Musto AE, Wilk A, Vashistha H, Zapata A, Walker C, Velasco-Gonzalez C, Parsons C, Wieland S, Levitt D, Reiss K, Prakash O.

Neoplasia. 2014 Oct 23;16(10):874-82. doi: 10.1016/j.neo.2014.08.015. eCollection 2014 Oct.


Molecular mechanisms of fenofibrate-induced metabolic catastrophe and glioblastoma cell death.

Wilk A, Wyczechowska D, Zapata A, Dean M, Mullinax J, Marrero L, Parsons C, Peruzzi F, Culicchia F, Ochoa A, Grabacka M, Reiss K.

Mol Cell Biol. 2015 Jan;35(1):182-98. doi: 10.1128/MCB.00562-14. Epub 2014 Oct 20.


Subpopulations of myeloid-derived suppressor cells impair T cell responses through independent nitric oxide-related pathways.

Raber PL, Thevenot P, Sierra R, Wyczechowska D, Halle D, Ramirez ME, Ochoa AC, Fletcher M, Velasco C, Wilk A, Reiss K, Rodriguez PC.

Int J Cancer. 2014 Jun 15;134(12):2853-64. doi: 10.1002/ijc.28622. Epub 2013 Dec 3.


Effects of cigarette smoke extract on primary activated T cells.

Hernandez CP, Morrow K, Velasco C, Wyczechowska DD, Naura AS, Rodriguez PC.

Cell Immunol. 2013 Mar;282(1):38-43. doi: 10.1016/j.cellimm.2013.04.005. Epub 2013 Apr 22.


Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia.

Morrow K, Hernandez CP, Raber P, Del Valle L, Wilk AM, Majumdar S, Wyczechowska D, Reiss K, Rodriguez PC.

Leukemia. 2013 Mar;27(3):569-77. doi: 10.1038/leu.2012.247. Epub 2012 Aug 28.


L-arginine deprivation regulates cyclin D3 mRNA stability in human T cells by controlling HuR expression.

Rodriguez PC, Hernandez CP, Morrow K, Sierra R, Zabaleta J, Wyczechowska DD, Ochoa AC.

J Immunol. 2010 Nov 1;185(9):5198-204. doi: 10.4049/jimmunol.1001224. Epub 2010 Oct 1.


The distinctive role of small heat shock proteins in oncogenesis.

Laudanski K, Wyczechowska D.

Arch Immunol Ther Exp (Warsz). 2006 Mar-Apr;54(2):103-11. Epub 2006 Mar 28. Review.


Involvement of the p38 MAP kinase in Cr(VI)-induced growth arrest and apoptosis.

Wakeman TP, Wyczechowska D, Xu B.

Mol Cell Biochem. 2005 Nov;279(1-2):69-73.


Monocyte-related immunopathologies in trauma patients.

Laudanski K, Wyczechowska D.

Arch Immunol Ther Exp (Warsz). 2005 Jul-Aug;53(4):321-8. Review.


The effects of cladribine and fludarabine on DNA methylation in K562 cells.

Wyczechowska D, Fabianowska-Majewska K.

Biochem Pharmacol. 2003 Jan 15;65(2):219-25.


Purine metabolism in leukocytes and erythrocytes in Graves' or Hashimoto's disease.

Karbownik M, Zasada K, Wyczechowska D, Lewiński A, Fabianowska-Majewska K.

Endocr Res. 2002 Aug;28(3):207-15.


Evidence of inhibition of DNA methylation by fludarabine.

Wyczechowska D, Czyz M, Fabianowska-Majewska K.

Adv Exp Med Biol. 2000;486:349-53. No abstract available.


Inhibition of dna methylation by 5-aza-2'-deoxycytidine correlates with induction of K562 cells differentiation.

Fabianowska-Majewska K, Wyczechowska D, Czyz M.

Adv Exp Med Biol. 2000;486:343-7. No abstract available.


Common resistance mechanisms to nucleoside analogues in variants of the human erythroleukemic line K562.

Dumontet C, Bauchu EC, Fabianowska K, Lepoivre M, Wyczechowska D, Bodin F, Rolland MO.

Adv Exp Med Biol. 1999;457:571-7.


Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562.

Dumontet C, Fabianowska-Majewska K, Mantincic D, Callet Bauchu E, Tigaud I, Gandhi V, Lepoivre M, Peters GJ, Rolland MO, Wyczechowska D, Fang X, Gazzo S, Voorn DA, Vanier-Viornery A, MacKey J.

Br J Haematol. 1999 Jul;106(1):78-85.


Distinct inhibitory effects of 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine on DNA methyltransferase in human T-lymphocytes.

Wyczechowska D, Ruckemann K, Duley JA, Simmonds AH, Fabianowska-Majewska K.

Nucleosides Nucleotides. 1999 Apr-May;18(4-5):831-4.


Does 2-chlorodeoxyadenosine contribute to alteration of DNA methyltransferase activity?

Wyczechowska D, Fabianowska-Majewska K.

Adv Exp Med Biol. 1998;431:595-8. No abstract available.


2-Chloro-2'-deoxyadenosine (2CdA) biochemical aspects of antileukemic efficacy.

Fabianowska-Majewska K, Wyczechowska D.

Acta Pol Pharm. 1996 Jul-Aug;53(4):231-9. Review.


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