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Items: 11

1.

Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity.

Jin LL, Wybenga-Groot LE, Tong J, Taylor P, Minden MD, Trudel S, McGlade CJ, Moran MF.

Mol Cell Proteomics. 2015 Mar;14(3):695-706. doi: 10.1074/mcp.M114.044404. Epub 2015 Jan 13.

2.

RTK SLAP down: the emerging role of Src-like adaptor protein as a key player in receptor tyrosine kinase signaling.

Wybenga-Groot LE, McGlade CJ.

Cell Signal. 2015 Feb;27(2):267-74. doi: 10.1016/j.cellsig.2014.11.010. Epub 2014 Nov 18. Review.

PMID:
25446260
3.

Structural basis of Rad53 kinase activation by dimerization and activation segment exchange.

Wybenga-Groot LE, Ho CS, Sweeney FD, Ceccarelli DF, McGlade CJ, Durocher D, Sicheri F.

Cell Signal. 2014 Sep;26(9):1825-36. doi: 10.1016/j.cellsig.2014.05.004. Epub 2014 May 9.

PMID:
24815189
4.

Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through β-sheet formation.

Wybenga-Groot LE, McGlade CJ.

Cell Signal. 2013 Dec;25(12):2702-8. doi: 10.1016/j.cellsig.2013.08.040. Epub 2013 Sep 7.

PMID:
24018043
5.

Biochemical and computational analysis of LNX1 interacting proteins.

Wolting CD, Griffiths EK, Sarao R, Prevost BC, Wybenga-Groot LE, McGlade CJ.

PLoS One. 2011;6(11):e26248. doi: 10.1371/journal.pone.0026248. Epub 2011 Nov 8.

6.

A conserved mechanism of autoinhibition for the AMPK kinase domain: ATP-binding site and catalytic loop refolding as a means of regulation.

Littler DR, Walker JR, Davis T, Wybenga-Groot LE, Finerty PJ Jr, Newman E, Mackenzie F, Dhe-Paganon S.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Feb 1;66(Pt 2):143-51. doi: 10.1107/S1744309109052543. Epub 2010 Jan 27.

7.

Analysis of EphA4 receptor tyrosine kinase substrate specificity using peptide-based arrays.

Warner N, Wybenga-Groot LE, Pawson T.

FEBS J. 2008 May;275(10):2561-73. doi: 10.1111/j.1742-4658.2008.06405.x. Epub 2008 Apr 15.

8.

A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases.

Wiesner S, Wybenga-Groot LE, Warner N, Lin H, Pawson T, Forman-Kay JD, Sicheri F.

EMBO J. 2006 Oct 4;25(19):4686-96. Epub 2006 Sep 14.

9.
10.

Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region.

Wybenga-Groot LE, Baskin B, Ong SH, Tong J, Pawson T, Sicheri F.

Cell. 2001 Sep 21;106(6):745-57.

11.

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