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Items: 18

1.

Amorphous protein aggregates stimulate plasminogen activation, leading to release of cytotoxic fragments that are clients for extracellular chaperones.

Constantinescu P, Brown RA, Wyatt AR, Ranson M, Wilson MR.

J Biol Chem. 2017 Sep 1;292(35):14425-14437. doi: 10.1074/jbc.M117.786657. Epub 2017 Jul 14.

2.

PZP and PAI-2: Structurally-diverse, functionally similar pregnancy proteins?

Wyatt AR, Cater JH, Ranson M.

Int J Biochem Cell Biol. 2016 Oct;79:113-117. doi: 10.1016/j.biocel.2016.08.018. Epub 2016 Aug 21. Review.

PMID:
27554634
3.

Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies.

Wyatt AR, Kumita JR, Farrawell NE, Dobson CM, Wilson MR.

PLoS One. 2015 Jun 23;10(6):e0130036. doi: 10.1371/journal.pone.0130036. eCollection 2015.

4.

Irreducible superolateral dislocation of the glenohumeral joint.

Wyatt AR 2nd, Porrino J, Shah S, Hsu JE.

Skeletal Radiol. 2015 Sep;44(9):1387-91. doi: 10.1007/s00256-015-2183-8. Epub 2015 Jun 9.

PMID:
26051805
5.

Hypochlorite-induced structural modifications enhance the chaperone activity of human α2-macroglobulin.

Wyatt AR, Kumita JR, Mifsud RW, Gooden CA, Wilson MR, Dobson CM.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2081-90. doi: 10.1073/pnas.1403379111. Epub 2014 May 5.

6.

Protease-activated alpha-2-macroglobulin can inhibit amyloid formation via two distinct mechanisms.

Wyatt AR, Constantinescu P, Ecroyd H, Dobson CM, Wilson MR, Kumita JR, Yerbury JJ.

FEBS Lett. 2013 Mar 1;587(5):398-403. doi: 10.1016/j.febslet.2013.01.020. Epub 2013 Jan 23.

7.

Extracellular chaperones and proteostasis.

Wyatt AR, Yerbury JJ, Ecroyd H, Wilson MR.

Annu Rev Biochem. 2013;82:295-322. doi: 10.1146/annurev-biochem-072711-163904. Epub 2013 Jan 23. Review.

PMID:
23350744
8.

Acute phase proteins are major clients for the chaperone action of α₂-macroglobulin in human plasma.

Wyatt AR, Zammit NW, Wilson MR.

Cell Stress Chaperones. 2013 Mar;18(2):161-70. doi: 10.1007/s12192-012-0365-z. Epub 2012 Aug 16. Erratum in: Cell Stress Chaperones. 2013 Sep;18(5):683. Zammit, Nathan W [added].

9.

Roles of extracellular chaperones in amyloidosis.

Wyatt AR, Yerbury JJ, Dabbs RA, Wilson MR.

J Mol Biol. 2012 Aug 24;421(4-5):499-516. doi: 10.1016/j.jmb.2012.01.004. Epub 2012 Jan 10. Review.

PMID:
22248589
10.

Extracellular chaperones.

Dabbs RA, Wyatt AR, Yerbury JJ, Ecroyd H, Wilson MR.

Top Curr Chem. 2013;328:241-68. doi: 10.1007/128_2011_262. Review.

PMID:
22076079
11.

Extracellular Chaperones.

Dabbs RA, Wyatt AR, Yerbury JJ, Ecroyd H, Wilson MR.

Top Curr Chem. 2010 Aug 27. [Epub ahead of print]

PMID:
21516385
12.

Clusterin facilitates in vivo clearance of extracellular misfolded proteins.

Wyatt AR, Yerbury JJ, Berghofer P, Greguric I, Katsifis A, Dobson CM, Wilson MR.

Cell Mol Life Sci. 2011 Dec;68(23):3919-31. doi: 10.1007/s00018-011-0684-8). Epub 2011 Apr 20.

PMID:
21505792
13.

Identification of human plasma proteins as major clients for the extracellular chaperone clusterin.

Wyatt AR, Wilson MR.

J Biol Chem. 2010 Feb 5;285(6):3532-9. doi: 10.1074/jbc.M109.079566. Epub 2009 Dec 7.

14.

Therapeutic targets in extracellular protein deposition diseases.

Wyatt AR, Yerbury JJ, Poon S, Wilson MR.

Curr Med Chem. 2009;16(22):2855-66. Review.

PMID:
19689268
15.

Structural characterization of clusterin-chaperone client protein complexes.

Wyatt AR, Yerbury JJ, Wilson MR.

J Biol Chem. 2009 Aug 14;284(33):21920-7. doi: 10.1074/jbc.M109.033688. Epub 2009 Jun 17.

16.

Modular fluorescent benzobis(imidazolium) salts: syntheses, photophysical analyses, and applications.

Boydston AJ, Vu PD, Dykhno OL, Chang V, Wyatt AR 2nd, Stockett AS, Ritschdorff ET, Shear JB, Bielawski CW.

J Am Chem Soc. 2008 Mar 12;130(10):3143-56. doi: 10.1021/ja7102247. Epub 2008 Feb 14.

PMID:
18271588
17.

Quality control of protein folding in extracellular space.

Yerbury JJ, Stewart EM, Wyatt AR, Wilson MR.

EMBO Rep. 2005 Dec;6(12):1131-6. Review.

18.

Prevalence and clinical implications of anthelmintic resistance in cyathostomes of horses.

Tarigo-Martinie JL, Wyatt AR, Kaplan RM.

J Am Vet Med Assoc. 2001 Jun 15;218(12):1957-60.

PMID:
11417741

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