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Items: 1 to 50 of 215

1.

RNA-Seq detects a SAMD12-EXT1 fusion transcript and leads to the discovery of an EXT1 deletion in a child with multiple osteochondromas.

Oliver GR, Blackburn PR, Ellingson MS, Conboy E, Pinto E Vairo F, Webley M, Thorland E, Ferber M, Van Hul E, van der Werf IM, Wuyts W, Babovic-Vuksanovic D, Klee EW.

Mol Genet Genomic Med. 2019 Jan 10:e00560. doi: 10.1002/mgg3.560. [Epub ahead of print]

2.

Presentation, diagnosis and clinical course of the spectrum of progressive-fibrosing interstitial lung diseases.

Cottin V, Hirani NA, Hotchkin DL, Nambiar AM, Ogura T, Otaola M, Skowasch D, Park JS, Poonyagariyagorn HK, Wuyts W, Wells AU.

Eur Respir Rev. 2018 Dec 21;27(150). pii: 180076. doi: 10.1183/16000617.0076-2018. Print 2018 Dec 31. Review.

3.

Effects of Corticosteroid Treatment and Antigen Avoidance in a Large Hypersensitivity Pneumonitis Cohort: A Single-Centre Cohort Study.

De Sadeleer LJ, Hermans F, De Dycker E, Yserbyt J, Verschakelen JA, Verbeken EK, Verleden GM, Wuyts WA.

J Clin Med. 2018 Dec 21;8(1). pii: E14. doi: 10.3390/jcm8010014.

4.

Baseline clinical characteristics, comorbidities and prescribed medication in a real-world population of patients with idiopathic pulmonary fibrosis: the PROOF registry.

Wuyts WA, Dahlqvist C, Slabbynck H, Schlesser M, Gusbin N, Compere C, Maddens S, Kirchgaessler KU, Bartley K, Bondue B.

BMJ Open Respir Res. 2018 Nov 21;5(1):e000331. doi: 10.1136/bmjresp-2018-000331. eCollection 2018.

5.

Idiopathic Pulmonary Fibrosis for Cardiologists: Differential Diagnosis, Cardiovascular Comorbidities, and Patient Management.

van Cleemput J, Sonaglioni A, Wuyts WA, Bengus M, Stauffer JL, Harari S.

Adv Ther. 2018 Dec 15. doi: 10.1007/s12325-018-0857-z. [Epub ahead of print] Review.

PMID:
30554332
6.

Nintedanib in Idiopathic Pulmonary Fibrosis: Practical Management Recommendations for Potential Adverse Events.

Bendstrup E, Wuyts W, Alfaro T, Chaudhuri N, Cornelissen R, Kreuter M, Melgaard Nielsen K, Münster AB, Myllärniemi M, Ravaglia C, Vanuytsel T, Wijsenbeek M.

Respiration. 2018 Dec 13:1-12. doi: 10.1159/000495046. [Epub ahead of print] Review.

PMID:
30544129
7.

Determinants of survival in lung transplantation patients with idiopathic pulmonary fibrosis: a retrospective cohort study.

Tuyls S, Verleden SE, Wuyts WA, Yserbyt J, Vos R, Verleden GM.

Transpl Int. 2018 Nov 28. doi: 10.1111/tri.13382. [Epub ahead of print]

PMID:
30488486
8.

Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis.

McDonough JE, Kaminski N, Thienpont B, Hogg JC, Vanaudenaerde BM, Wuyts WA.

Thorax. 2019 Feb;74(2):132-140. doi: 10.1136/thoraxjnl-2018-211929. Epub 2018 Oct 26.

9.

Short and long-term effects of pulmonary rehabilitation in interstitial lung diseases: a randomised controlled trial.

Perez-Bogerd S, Wuyts W, Barbier V, Demeyer H, Van Muylem A, Janssens W, Troosters T.

Respir Res. 2018 Sep 20;19(1):182. doi: 10.1186/s12931-018-0884-y.

10.

Response.

De Sadeleer LJ, Wuyts WA.

Chest. 2018 Sep;154(3):714-715. doi: 10.1016/j.chest.2018.06.020. No abstract available.

PMID:
30195350
11.

BAL Cell Gene Expression is Indicative of Outcome and Airway Basal Cell Involvement in IPF.

Prasse A, Binder H, Schupp JC, Kayser G, Bargagli E, Jaeger B, Hess M, Rittinghausen S, Vuga L, Lynn H, Violette S, Jung B, Quast K, Vanaudenaerde B, Xu Y, Hohlfeld JM, Krug N, Herazo-Maya JD, Rottoli P, Wuyts WA, Kaminski N.

Am J Respir Crit Care Med. 2018 Aug 24. doi: 10.1164/rccm.201712-2551OC. [Epub ahead of print]

PMID:
30141961
12.

Idiopathic pulmonary fibrosis: time for greater expectations?

Wuyts W, Cottin V.

Eur Respir J. 2018 Aug 2;52(2). pii: 1801312. doi: 10.1183/13993003.01312-2018. Print 2018 Aug. No abstract available.

PMID:
30072545
13.

Metformin Does Not Affect Clinically Relevant Outcomes in Patients with Idiopathic Pulmonary Fibrosis.

Spagnolo P, Kreuter M, Maher TM, Wuyts W, Bonella F, Corte TJ, Kopf S, Weycker D, Kirchgaessler KU, Ryerson CJ.

Respiration. 2018;96(4):314-322. doi: 10.1159/000489668. Epub 2018 Jul 19.

PMID:
30025392
14.

Reply to Rajchgot et al.: Combination Nintedanib and Pirfenidone for Treatment of Idiopathic Pulmonary Fibrosis.

Vancheri C, Kreuter M, Richeldi L, Quaresma M, Stowasser S, Wuyts WA.

Am J Respir Crit Care Med. 2018 Oct 15;198(8):1105-1106. doi: 10.1164/rccm.201806-1116LE. No abstract available.

PMID:
30025211
15.

Pirfenidone in restrictive allograft syndrome after lung transplantation: A case series.

Vos R, Wuyts WA, Gheysens O, Goffin KE, Schaevers V, Verleden SE, Van Herck A, Sacreas A, Heigl T, McDonough JE, Yserbyt J, Godinas L, Dupont LJ, Neyrinck AP, Van Raemdonck DE, Verbeken EK, Vanaudenaerde BM, Verleden GM.

Am J Transplant. 2018 Dec;18(12):3045-3059. doi: 10.1111/ajt.15019. Epub 2018 Aug 17.

PMID:
30019840
16.

The SLC40A1 R178Q mutation is a recurrent cause of hemochromatosis and is associated with a novel pathogenic mechanism.

Ka C, Guellec J, Pepermans X, Kannengiesser C, Ged C, Wuyts W, Cassiman D, de Ledinghen V, Varet B, de Kerguenec C, Oudin C, Gourlaouen I, Lefebvre T, Férec C, Callebaut I, Le Gac G.

Haematologica. 2018 Nov;103(11):1796-1805. doi: 10.3324/haematol.2018.189845. Epub 2018 Jul 12.

17.

A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis.

McDonough JE, Martens DS, Tanabe N, Ahangari F, Verleden SE, Maes K, Verleden GM, Kaminski N, Hogg JC, Nawrot TS, Wuyts WA, Vanaudenaerde BM.

Respir Res. 2018 Jul 9;19(1):132. doi: 10.1186/s12931-018-0838-4.

18.

Elucidating the genetic architecture of Adams-Oliver syndrome in a large European cohort.

Meester JAN, Sukalo M, Schröder KC, Schanze D, Baynam G, Borck G, Bramswig NC, Duman D, Gilbert-Dussardier B, Holder-Espinasse M, Itin P, Johnson DS, Joss S, Koillinen H, McKenzie F, Morton J, Nelle H, Reardon W, Roll C, Salih MA, Savarirayan R, Scurr I, Splitt M, Thompson E, Titheradge H, Travers CP, Van Maldergem L, Whiteford M, Wieczorek D, Vandeweyer G, Trembath R, Van Laer L, Loeys BL, Zenker M, Southgate L, Wuyts W.

Hum Mutat. 2018 Sep;39(9):1246-1261. doi: 10.1002/humu.23567. Epub 2018 Jul 4.

19.

Clinical behaviour of patients exposed to organic dust and diagnosed with idiopathic pulmonary fibrosis.

De Sadeleer LJ, Verleden SE, De Dycker E, Yserbyt J, Verschakelen JA, Verbeken EK, Nemery B, Verleden GM, Hermans F, Vanaudenaerde BM, Wuyts WA.

Respirology. 2018 Dec;23(12):1160-1165. doi: 10.1111/resp.13342. Epub 2018 Jun 13.

PMID:
29897160
20.

Role of Targeted Next Generation Sequencing in the Etiological Work-Up of Congenitally Deaf Children.

Boudewyns A, van den Ende J, Sommen M, Wuyts W, Peeters N, Van de Heyning P, Van Camp G.

Otol Neurotol. 2018 Jul;39(6):732-738. doi: 10.1097/MAO.0000000000001847.

PMID:
29889784
21.

Safety, tolerability, pharmacokinetics, and pharmacodynamics of GLPG1690, a novel autotaxin inhibitor, to treat idiopathic pulmonary fibrosis (FLORA): a phase 2a randomised placebo-controlled trial.

Maher TM, van der Aar EM, Van de Steen O, Allamassey L, Desrivot J, Dupont S, Fagard L, Ford P, Fieuw A, Wuyts W.

Lancet Respir Med. 2018 Aug;6(8):627-635. doi: 10.1016/S2213-2600(18)30181-4. Epub 2018 May 20.

22.

The aging lung: tissue telomere shortening in health and disease.

Everaerts S, Lammertyn EJ, Martens DS, De Sadeleer LJ, Maes K, van Batenburg AA, Goldschmeding R, van Moorsel CHM, Dupont LJ, Wuyts WA, Vos R, Gayan-Ramirez G, Kaminski N, Hogg JC, Janssens W, Verleden GM, Nawrot TS, Verleden SE, McDonough JE, Vanaudenaerde BM.

Respir Res. 2018 May 11;19(1):95. doi: 10.1186/s12931-018-0794-z.

23.

Sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: A Phase IIb, randomised, double-blind, placebo-controlled study - Rationale and study design.

Behr J, Nathan SD, Harari S, Wuyts W, Kirchgaessler KU, Bengus M, Gilberg F, Wells AU.

Respir Med. 2018 May;138:13-20. doi: 10.1016/j.rmed.2018.03.019. Epub 2018 Mar 16.

24.

Diagnostic Ability of a Dynamic Multidisciplinary Discussion in Interstitial Lung Diseases: A Retrospective Observational Study of 938 Cases.

De Sadeleer LJ, Meert C, Yserbyt J, Slabbynck H, Verschakelen JA, Verbeken EK, Weynand B, De Langhe E, Lenaerts JL, Nemery B, Van Raemdonck D, Verleden GM, Wells AU, Wuyts WA.

Chest. 2018 Jun;153(6):1416-1423. doi: 10.1016/j.chest.2018.03.026. Epub 2018 Mar 30.

PMID:
29608882
25.

Multiple Solid Organ Transplantation in Telomeropathy: Case Series and Literature Review.

Lebeer M, Wuyts WA, Cassiman D, Laleman W, Nevens F, Pirenne J, Monbaliu D, Roskams T, Verbeken EK, Neyrinck AP, Van Raemdonck DE, Verleden GM, Vos R.

Transplantation. 2018 Oct;102(10):1747-1755. doi: 10.1097/TP.0000000000002198.

PMID:
29596117
26.

Prevalence of Myositis-Specific Antibodies in Idiopathic Interstitial Pneumonias.

De Sadeleer LJ, De Langhe E, Bodart N, Vigneron A, Bossuyt X, Wuyts WA.

Lung. 2018 Jun;196(3):329-333. doi: 10.1007/s00408-018-0108-8. Epub 2018 Mar 12.

PMID:
29532165
27.

Fluxomic assay-assisted diagnosis orientation in a cohort of 11 patients with myopathic form of CPT2 deficiency.

Fontaine M, Kim I, Dessein AF, Mention-Mulliez K, Dobbelaere D, Douillard C, Sole G, Schiff M, Jaussaud R, Espil-Taris C, Boutron A, Wuyts W, Acquaviva C, Vianey-Saban C, Roland D, Joncquel-Chevalier Curt M, Vamecq J.

Mol Genet Metab. 2018 Apr;123(4):441-448. doi: 10.1016/j.ymgme.2018.02.005. Epub 2018 Feb 12.

PMID:
29478820
28.

Bi-allelic inactivating variants in the COCH gene cause autosomal recessive prelingual hearing impairment.

JanssensdeVarebeke SPF, Van Camp G, Peeters N, Elinck E, Widdershoven J, Cox T, Deben K, Ketelslagers K, Crins T, Wuyts W.

Eur J Hum Genet. 2018 Apr;26(4):587-591. doi: 10.1038/s41431-017-0066-2. Epub 2018 Feb 15.

PMID:
29449721
29.

Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic?

Wolters PJ, Blackwell TS, Eickelberg O, Loyd JE, Kaminski N, Jenkins G, Maher TM, Molina-Molina M, Noble PW, Raghu G, Richeldi L, Schwarz MI, Selman M, Wuyts WA, Schwartz DA.

Lancet Respir Med. 2018 Feb;6(2):154-160. doi: 10.1016/S2213-2600(18)30007-9. Review.

30.

Phenotypes of organ involvement in sarcoidosis.

Schupp JC, Freitag-Wolf S, Bargagli E, Mihailović-Vučinić V, Rottoli P, Grubanovic A, Müller A, Jochens A, Tittmann L, Schnerch J, Olivieri C, Fischer A, Jovanovic D, Filipovic S, Videnovic-Ivanovic J, Bresser P, Jonkers R, O'Reilly K, Ho LP, Gaede KI, Zabel P, Dubaniewicz A, Marshall B, Kieszko R, Milanowski J, Günther A, Weihrich A, Petrek M, Kolek V, Keane MP, O'Beirne S, Donnelly S, Haraldsdottir SO, Jorundsdottir KB, Costabel U, Bonella F, Wallaert B, Grah C, Peroš-Golubičić T, Luisetti M, Kadija Z, Pabst S, Grohé C, Strausz J, Vašáková M, Sterclova M, Millar A, Homolka J, Slováková A, Kendrick Y, Crawshaw A, Wuyts W, Spencer L, Pfeifer M, Valeyre D, Poletti V, Wirtz H, Prasse A, Schreiber S, Krawczak M, Müller-Quernheim J.

Eur Respir J. 2018 Jan 25;51(1). pii: 1700991. doi: 10.1183/13993003.00991-2017. Print 2018 Jan.

PMID:
29371378
31.

Unfavourable outcome of glucocorticoid treatment in suspected idiopathic pulmonary fibrosis.

Wiertz IA, Wuyts WA, van Moorsel CHM, Vorselaars ADM, van Es HW, van Oosterhout MFM, Grutters JC.

Respirology. 2018 Mar;23(3):311-317. doi: 10.1111/resp.13230. Epub 2017 Dec 5.

32.

Long-term treatment of patients with idiopathic pulmonary fibrosis with nintedanib: results from the TOMORROW trial and its open-label extension.

Richeldi L, Kreuter M, Selman M, Crestani B, Kirsten AM, Wuyts WA, Xu Z, Bernois K, Stowasser S, Quaresma M, Costabel U.

Thorax. 2018 Jun;73(6):581-583. doi: 10.1136/thoraxjnl-2016-209701. Epub 2017 Oct 9.

33.

Nintedanib with Add-on Pirfenidone in Idiopathic Pulmonary Fibrosis. Results of the INJOURNEY Trial.

Vancheri C, Kreuter M, Richeldi L, Ryerson CJ, Valeyre D, Grutters JC, Wiebe S, Stansen W, Quaresma M, Stowasser S, Wuyts WA; INJOURNEY Trial Investigators.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):356-363. doi: 10.1164/rccm.201706-1301OC.

PMID:
28889759
34.

Diagnostic accuracy of a clinical diagnosis of idiopathic pulmonary fibrosis: an international case-cohort study.

Walsh SLF, Maher TM, Kolb M, Poletti V, Nusser R, Richeldi L, Vancheri C, Wilsher ML, Antoniou KM, Behr J, Bendstrup E, Brown K, Calandriello L, Corte TJ, Cottin V, Crestani B, Flaherty K, Glaspole I, Grutters J, Inoue Y, Kokosi M, Kondoh Y, Kouranos V, Kreuter M, Johannson K, Judge E, Ley B, Margaritopoulos G, Martinez FJ, Molina-Molina M, Morais A, Nunes H, Raghu G, Ryerson CJ, Selman M, Spagnolo P, Taniguchi H, Tomassetti S, Valeyre D, Wijsenbeek M, Wuyts W, Hansell D, Wells A; IPF Project Consortium.

Eur Respir J. 2017 Aug 31;50(2). pii: 1700936. doi: 10.1183/13993003.00936-2017. Print 2017 Aug.

PMID:
28860269
35.

Solid Organ Transplantation in Sarcoidosis.

Yserbyt J, Wuyts WA, Verleden SE, Verleden GM, Van Raemdonck DE, Verbeken EK, Vanaudenaerde BM, Vos R.

Semin Respir Crit Care Med. 2017 Aug;38(4):538-545. doi: 10.1055/s-0037-1602383. Epub 2017 Jul 27. Review. No abstract available.

PMID:
28750467
36.

Molecular diagnostics for hereditary hearing loss in children.

Sommen M, Wuyts W, Van Camp G.

Expert Rev Mol Diagn. 2017 Aug;17(8):751-760. doi: 10.1080/14737159.2017.1340834. Epub 2017 Jun 19. Review.

PMID:
28593790
37.

Acute exacerbations of interstitial lung disease: lessons from idiopathic pulmonary fibrosis.

Spagnolo P, Wuyts W.

Curr Opin Pulm Med. 2017 Sep;23(5):411-417. doi: 10.1097/MCP.0000000000000405. Review.

PMID:
28582317
38.

Two novel MYLK nonsense mutations causing thoracic aortic aneurysms/dissections in patients without apparent family history.

Luyckx I, Proost D, Hendriks JMH, Saenen J, Van Craenenbroeck EM, Vermeulen T, Peeters N, Wuyts W, Rodrigus I, Verstraeten A, Van Laer L, Loeys BL.

Clin Genet. 2017 Oct;92(4):444-446. doi: 10.1111/cge.13000. Epub 2017 Apr 12. No abstract available. Erratum in: Clin Genet. 2018 Apr;93(4):938.

PMID:
28401540
39.

Antacid Therapy and Disease Progression in Patients with Idiopathic Pulmonary Fibrosis Who Received Pirfenidone.

Kreuter M, Spagnolo P, Wuyts W, Renzoni E, Koschel D, Bonella F, Maher TM, Kolb M, Weycker D, Kirchgässler KU, Costabel U.

Respiration. 2017;93(6):415-423. doi: 10.1159/000468546. Epub 2017 Apr 12.

40.

Targeted Next-Generation Sequencing of 51 Genes Involved in Primary Electrical Disease.

Proost D, Saenen J, Vandeweyer G, Rotthier A, Alaerts M, Van Craenenbroeck EM, Van Crombruggen J, Mortier G, Wuyts W, Vrints C, Del Favero J, Loeys B, Van Laer L.

J Mol Diagn. 2017 May;19(3):445-459. doi: 10.1016/j.jmoldx.2017.01.010. Epub 2017 Mar 22.

PMID:
28341588
41.

Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial.

Raghu G, Brown KK, Collard HR, Cottin V, Gibson KF, Kaner RJ, Lederer DJ, Martinez FJ, Noble PW, Song JW, Wells AU, Whelan TP, Wuyts W, Moreau E, Patterson SD, Smith V, Bayly S, Chien JW, Gong Q, Zhang JJ, O'Riordan TG.

Lancet Respir Med. 2017 Jan;5(1):22-32. doi: 10.1016/S2213-2600(16)30421-0. Epub 2016 Dec 7.

PMID:
27939076
42.

Trichorhinophalangeal syndrome type II presenting with short stature in a child.

Hazan F, Korkmaz HA, Yararbaş K, Wuyts W, Tükün A; Collaborator.

Arch Argent Pediatr. 2016 Dec 1;114(6):e403-e407. doi: 10.5546/aap.2016.eng.e403. English, Spanish.

43.

Safety and efficacy of bridging to lung transplantation with antifibrotic drugs in idiopathic pulmonary fibrosis: a case series.

Delanote I, Wuyts WA, Yserbyt J, Verbeken EK, Verleden GM, Vos R.

BMC Pulm Med. 2016 Nov 18;16(1):156.

44.

Daily Home Spirometry: A New Milestone in the Field of Pulmonary Fibrosis.

Wuyts WA, Spagnolo P, Bonella F, Yserbyt J, Verleden GM.

Am J Respir Crit Care Med. 2016 Oct 15;194(8):1033-1034. No abstract available.

PMID:
27739891
45.

Thin-Section CT Features of Idiopathic Pulmonary Fibrosis Correlated with Micro-CT and Histologic Analysis.

Mai C, Verleden SE, McDonough JE, Willems S, De Wever W, Coolen J, Dubbeldam A, Van Raemdonck DE, Verbeken EK, Verleden GM, Hogg JC, Vanaudenaerde BM, Wuyts WA, Verschakelen JA.

Radiology. 2017 Apr;283(1):252-263. doi: 10.1148/radiol.2016152362. Epub 2016 Oct 6.

46.

Loss-of-function mutations in the X-linked biglycan gene cause a severe syndromic form of thoracic aortic aneurysms and dissections.

Meester JA, Vandeweyer G, Pintelon I, Lammens M, Van Hoorick L, De Belder S, Waitzman K, Young L, Markham LW, Vogt J, Richer J, Beauchesne LM, Unger S, Superti-Furga A, Prsa M, Dhillon R, Reyniers E, Dietz HC, Wuyts W, Mortier G, Verstraeten A, Van Laer L, Loeys BL.

Genet Med. 2017 Apr;19(4):386-395. doi: 10.1038/gim.2016.126. Epub 2016 Sep 15.

47.

Anti-acid treatment in patients with IPF: interpret results from post-hoc, subgroup, and exploratory analyses with great caution - Authors' reply.

Kreuter M, Wuyts W, Renzoni E, Koschel D, Maher TM, Kolb M, Weycker D, Spagnolo P, Kirchgaessler KU, Herth FJF, Costabel U.

Lancet Respir Med. 2016 Sep;4(9):e48. doi: 10.1016/S2213-2600(16)30235-1. No abstract available.

PMID:
27599251
48.

Sarcoidosis-Like Lesions: Another Paradoxical Reaction to Anti-TNF Therapy?

Decock A, Van Assche G, Vermeire S, Wuyts W, Ferrante M.

J Crohns Colitis. 2017 Mar 1;11(3):378-383. doi: 10.1093/ecco-jcc/jjw155. Review.

PMID:
27591675
49.

Gastro-oesophageal reflux and idiopathic pulmonary fibrosis: in search of evidence.

Wuyts W, Crestani B.

Eur Respir J. 2016 Sep;48(3):623-5. doi: 10.1183/13993003.01444-2016. No abstract available.

50.

First Data on Efficacy and Safety of Nintedanib in Patients with Idiopathic Pulmonary Fibrosis and Forced Vital Capacity of ≤50 % of Predicted Value.

Wuyts WA, Kolb M, Stowasser S, Stansen W, Huggins JT, Raghu G.

Lung. 2016 Oct;194(5):739-43. doi: 10.1007/s00408-016-9912-1. Epub 2016 Jul 4.

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