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Items: 1 to 50 of 711

1.

Fenfluramine: Back From the Dead.

Wurtman RJ, Wurtman J.

Clin Ther. 2018 Aug;40(8):1420-1422. doi: 10.1016/j.clinthera.2018.07.009. Epub 2018 Aug 11. No abstract available.

PMID:
30108000
2.

Synapse formation in the brain can be enhanced by co-administering three specific nutrients.

Wurtman RJ.

Eur J Pharmacol. 2017 Dec 15;817:20-21. doi: 10.1016/j.ejphar.2017.09.038. Epub 2017 Oct 12.

PMID:
29031899
3.

Connectomics and other novel methods for examining neural systems.

Wurtman RJ.

Metabolism. 2017 Apr;69S:S13-S15. doi: 10.1016/j.metabol.2017.01.015. Epub 2017 Jan 11. Review.

PMID:
28139215
4.

Depression can beget obesity can beget depression.

Wurtman JJ, Wurtman RJ.

J Clin Psychiatry. 2015 Dec;76(12):e1619-21. doi: 10.4088/JCP.15com10380. No abstract available.

5.

How Anticholinergic Drugs Might Promote Alzheimer's Disease: More Amyloid-β and Less Phosphatidylcholine.

Wurtman RJ.

J Alzheimers Dis. 2015;46(4):983-7. doi: 10.3233/JAD-150290. Review.

PMID:
26402628
6.

Evidence for the existence of pyrimidinergic transmission in rat brain.

Cansev M, Orhan F, Yaylagul EO, Isik E, Turkyilmaz M, Aydin S, Gumus A, Sevinc C, Coskun N, Ulus IH, Wurtman RJ.

Neuropharmacology. 2015 Apr;91:77-86. doi: 10.1016/j.neuropharm.2014.12.019. Epub 2014 Dec 23.

PMID:
25541414
7.

A nutritional approach to ameliorate altered phospholipid metabolism in Alzheimer's disease.

Hartmann T, van Wijk N, Wurtman RJ, Olde Rikkert MG, Sijben JW, Soininen H, Vellas B, Scheltens P.

J Alzheimers Dis. 2014;41(3):715-7. doi: 10.3233/JAD-141137.

PMID:
24898653
8.

A nutrient combination that can affect synapse formation.

Wurtman RJ.

Nutrients. 2014 Apr 23;6(4):1701-10. doi: 10.3390/nu6041701.

9.

Personalized medicine strategies for managing patients with parkinsonism and cognitive deficits.

Wurtman RJ.

Metabolism. 2013 Jan;62 Suppl 1:S27-9. doi: 10.1016/j.metabol.2012.08.025. Epub 2012 Sep 20.

PMID:
22999712
10.

Efficacy of Souvenaid in mild Alzheimer's disease: results from a randomized, controlled trial.

Scheltens P, Twisk JW, Blesa R, Scarpini E, von Arnim CA, Bongers A, Harrison J, Swinkels SH, Stam CJ, de Waal H, Wurtman RJ, Wieggers RL, Vellas B, Kamphuis PJ.

J Alzheimers Dis. 2012;31(1):225-36. doi: 10.3233/JAD-2012-121189.

PMID:
22766770
11.

Combined dietary folate, vitamin B-12, and vitamin B-6 intake influences plasma docosahexaenoic acid concentration in rats.

van Wijk N, Watkins CJ, Hageman RJ, Sijben JC, Kamphuis PG, Wurtman RJ, Broersen LM.

Nutr Metab (Lond). 2012 May 30;9(1):49. doi: 10.1186/1743-7075-9-49.

12.

Plasma choline concentration varies with different dietary levels of vitamins B6, B12 and folic acid in rats maintained on choline-adequate diets.

van Wijk N, Watkins CJ, Böhlke M, Maher TJ, Hageman RJ, Kamphuis PJ, Broersen LM, Wurtman RJ.

Br J Nutr. 2012 May;107(10):1408-12. doi: 10.1017/S0007114511004570. Epub 2011 Sep 15.

PMID:
21917195
13.

Non-nutritional uses of nutrients.

Wurtman RJ.

Eur J Pharmacol. 2011 Sep;668 Suppl 1:S10-5. doi: 10.1016/j.ejphar.2011.07.005. Epub 2011 Jul 27. Review.

PMID:
21816139
14.

Nutritional modifiers of aging brain function: use of uridine and other phosphatide precursors to increase formation of brain synapses.

Wurtman RJ, Cansev M, Sakamoto T, Ulus I.

Nutr Rev. 2010 Dec;68 Suppl 2:S88-101. doi: 10.1111/j.1753-4887.2010.00344.x. Review.

15.

Fibromyalgia and the complex regional pain syndrome: similarities in pathophysiology and treatment.

Wurtman RJ.

Metabolism. 2010 Oct;59 Suppl 1:S37-40. doi: 10.1016/j.metabol.2010.07.008. Review.

PMID:
20837192
16.

Efficacy of a medical food in mild Alzheimer's disease: A randomized, controlled trial.

Scheltens P, Kamphuis PJ, Verhey FR, Olde Rikkert MG, Wurtman RJ, Wilkinson D, Twisk JW, Kurz A.

Alzheimers Dement. 2010 Jan;6(1):1-10.e1. doi: 10.1016/j.jalz.2009.10.003.

PMID:
20129316
17.

Enhancing synaptogenesis in diseases characterized by deficiencies in brain synapses.

Wurtman RJ.

Front Psychiatry. 2010 Nov 18;1:147. doi: 10.3389/fpsyt.2010.00147. eCollection 2010. No abstract available.

18.

Nutrition and Alzheimer's disease: pre-clinical concepts.

Kamphuis PJ, Wurtman RJ.

Eur J Neurol. 2009 Sep;16 Suppl 1:12-8. doi: 10.1111/j.1468-1331.2009.02737.x. Review.

PMID:
19703215
19.

Use of phosphatide precursors to promote synaptogenesis.

Wurtman RJ, Cansev M, Sakamoto T, Ulus IH.

Annu Rev Nutr. 2009;29:59-87. doi: 10.1146/annurev-nutr-080508-141059. Review.

PMID:
19400698
20.

Synapse formation is enhanced by oral administration of uridine and DHA, the circulating precursors of brain phosphatides.

Wurtman RJ, Cansev M, Ulus IH.

J Nutr Health Aging. 2009 Mar;13(3):189-97. Review.

PMID:
19262950
21.

Giving uridine and/or docosahexaenoic acid orally to rat dams during gestation and nursing increases synaptic elements in brains of weanling pups.

Cansev M, Marzloff G, Sakamoto T, Ulus IH, Wurtman RJ.

Dev Neurosci. 2009;31(3):181-92. doi: 10.1159/000193394. Epub 2009 Jan 15.

PMID:
19145070
22.

Administration of docosahexaenoic acid, uridine and choline increases levels of synaptic membranes and dendritic spines in rodent brain.

Wurtman RJ, Cansev M, Sakamoto T, Ulus IH.

World Rev Nutr Diet. 2009;99:71-96. doi: 10.1159/000192998. Epub 2009 Jan 9. Review. No abstract available.

PMID:
19136840
23.

Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents.

Wurtman RJ.

Metabolism. 2008 Oct;57 Suppl 2:S6-10. doi: 10.1016/j.metabol.2008.07.007. Review.

24.

Restorative effects of uridine plus docosahexaenoic acid in a rat model of Parkinson's disease.

Cansev M, Ulus IH, Wang L, Maher TJ, Wurtman RJ.

Neurosci Res. 2008 Nov;62(3):206-9. doi: 10.1016/j.neures.2008.07.005. Epub 2008 Aug 3.

25.

Oral administration of circulating precursors for membrane phosphatides can promote the synthesis of new brain synapses.

Cansev M, Wurtman RJ, Sakamoto T, Ulus IH.

Alzheimers Dement. 2008 Jan;4(1 Suppl 1):S153-68. doi: 10.1016/j.jalz.2007.10.005. Epub 2007 Dec 21. Review.

26.

A roadmap for the prevention of dementia: the inaugural Leon Thal Symposium.

Khachaturian ZS, Petersen RC, Gauthier S, Buckholtz N, Corey-Bloom JP, Evans B, Fillit H, Foster N, Greenberg B, Grundman M, Sano M, Simpkins J, Schneider LS, Weiner MW, Galasko D, Hyman B, Kuller L, Schenk D, Snyder S, Thomas RG, Tuszynski MH, Vellas B, Wurtman RJ, Snyder PJ, Frank RA, Albert M, Doody R, Ferris S, Kaye J, Koo E, Morrison-Bogorad M, Reisberg B, Salmon DP, Gilman S, Mohs R, Aisen PS, Breitner JC, Cummings JL, Kawas C, Phelps C, Poirier J, Sabbagh M, Touchon J, Khachaturian AS, Bain LJ.

Alzheimers Dement. 2008 May;4(3):156-63. doi: 10.1016/j.jalz.2008.03.005. No abstract available.

27.

Endogenous melatonin levels and the fate of exogenous melatonin: age effects.

Zhdanova IV, Wurtman RJ, Balcioglu A, Kartashov AI, Lynch HJ.

J Gerontol A Biol Sci Med Sci. 1998 Jul;53(4):B293-8.

PMID:
18314560
28.
30.

Polyunsaturated fatty acids stimulate phosphatidylcholine synthesis in PC12 cells.

Richardson UI, Wurtman RJ.

Biochim Biophys Acta. 2007 Apr;1771(4):558-63. Epub 2007 Feb 6.

31.

Oral L-glutamine increases GABA levels in striatal tissue and extracellular fluid.

Wang L, Maher TJ, Wurtman RJ.

FASEB J. 2007 Apr;21(4):1227-32. Epub 2007 Jan 11.

PMID:
17218538
33.
34.

Narcolepsy and the hypocretins.

Wurtman RJ.

Metabolism. 2006 Oct;55(10 Suppl 2):S36-9. Review.

PMID:
16979425
35.

Inhibition of platelet-activating factor receptors in hippocampal plasma membranes attenuates the inflammatory nociceptive response in rats.

Teather LA, Afonso VM, Wurtman RJ.

Brain Res. 2006 Jun 30;1097(1):230-3. Epub 2006 Jun 13.

PMID:
16774744
36.

Cytidine and uridine increase striatal CDP-choline levels without decreasing acetylcholine synthesis or release.

Ulus IH, Watkins CJ, Cansev M, Wurtman RJ.

Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):563-77. Epub 2006 Apr 25.

PMID:
16636900
37.

Synaptic proteins and phospholipids are increased in gerbil brain by administering uridine plus docosahexaenoic acid orally.

Wurtman RJ, Ulus IH, Cansev M, Watkins CJ, Wang L, Marzloff G.

Brain Res. 2006 May 9;1088(1):83-92. Epub 2006 Apr 21.

PMID:
16631143
38.

The 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor pravastatin enhances neurite outgrowth in hippocampal neurons.

Pooler AM, Xi SC, Wurtman RJ.

J Neurochem. 2006 May;97(3):716-23. Epub 2006 Mar 29. Erratum in: J Neurochem. 2006 Aug;98(3):992.

39.

Oral uridine-5'-monophosphate (UMP) increases brain CDP-choline levels in gerbils.

Cansev M, Watkins CJ, van der Beek EM, Wurtman RJ.

Brain Res. 2005 Oct 5;1058(1-2):101-8. Epub 2005 Aug 29.

PMID:
16126180
40.
41.

Uridine enhances neurite outgrowth in nerve growth factor-differentiated PC12 [corrected].

Pooler AM, Guez DH, Benedictus R, Wurtman RJ.

Neuroscience. 2005;134(1):207-14. Erratum in: Neuroscience. 2005;135(2):657.

PMID:
15939540
42.

Genes, stress, and depression.

Wurtman RJ.

Metabolism. 2005 May;54(5 Suppl 1):16-9. Review.

PMID:
15877307
43.

Effects of exogenous melatonin on sleep: a meta-analysis.

Brzezinski A, Vangel MG, Wurtman RJ, Norrie G, Zhdanova I, Ben-Shushan A, Ford I.

Sleep Med Rev. 2005 Feb;9(1):41-50.

PMID:
15649737
44.
45.

Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia.

Pooler AM, Arjona AA, Lee RK, Wurtman RJ.

Neurosci Lett. 2004 May 20;362(2):127-30.

PMID:
15193769
46.

A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function.

Wang P, Saraswati S, Guan Z, Watkins CJ, Wurtman RJ, Littleton JT.

J Neurosci. 2004 May 12;24(19):4518-29.

47.

An animal model of antipsychotic-induced weight gain.

Arjona AA, Zhang SX, Adamson B, Wurtman RJ.

Behav Brain Res. 2004 Jun 4;152(1):121-7.

PMID:
15135975
48.

5-Hydroxy-L-tryptophan suppresses food intake in food-deprived and stressed rats.

Amer A, Breu J, McDermott J, Wurtman RJ, Maher TJ.

Pharmacol Biochem Behav. 2004 Jan;77(1):137-43.

PMID:
14724051
49.

Dietary cytidine (5')-diphosphocholine supplementation protects against development of memory deficits in aging rats.

Teather LA, Wurtman RJ.

Prog Neuropsychopharmacol Biol Psychiatry. 2003 Jun;27(4):711-7.

PMID:
12787861
50.

Stimulation of CDP-choline synthesis by uridine or cytidine in PC12 rat pheochromocytoma cells.

Richardson UI, Watkins CJ, Pierre C, Ulus IH, Wurtman RJ.

Brain Res. 2003 May 9;971(2):161-7.

PMID:
12706232

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