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Items: 23


IL-10 transcription is negatively regulated by BAF180, a component of the SWI/SNF chromatin remodeling enzyme.

Wurster AL, Precht P, Becker KG, Wood WH 3rd, Zhang Y, Wang Z, Pazin MJ.

BMC Immunol. 2012 Feb 15;13:9. doi: 10.1186/1471-2172-13-9.


ATP-dependent chromatin remodeling in T cells.

Wurster AL, Pazin MJ.

Biochem Cell Biol. 2012 Feb;90(1):1-13. doi: 10.1139/o11-042. Epub 2011 Oct 14. Review.


CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genes.

Potts RC, Zhang P, Wurster AL, Precht P, Mughal MR, Wood WH 3rd, Zhang Y, Becker KG, Mattson MP, Pazin MJ.

PLoS One. 2011;6(9):e24515. doi: 10.1371/journal.pone.0024515. Epub 2011 Sep 13.


NF-κB and BRG1 bind a distal regulatory element in the IL-3/GM-CSF locus.

Wurster AL, Precht P, Pazin MJ.

Mol Immunol. 2011 Sep;48(15-16):2178-88. doi: 10.1016/j.molimm.2011.07.016. Epub 2011 Aug 9.


Dynamic BRG1 recruitment during T helper differentiation and activation reveals distal regulatory elements.

De S, Wurster AL, Precht P, Wood WH 3rd, Becker KG, Pazin MJ.

Mol Cell Biol. 2011 Apr;31(7):1512-27. doi: 10.1128/MCB.00920-10. Epub 2011 Jan 24.


The SNF2H chromatin remodeling enzyme has opposing effects on cytokine gene expression.

Precht P, Wurster AL, Pazin MJ.

Mol Immunol. 2010 Jul;47(11-12):2038-46. doi: 10.1016/j.molimm.2010.04.009. Epub 2010 May 15.


Interleukin-21 is required for the development of type 1 diabetes in NOD mice.

Sutherland AP, Van Belle T, Wurster AL, Suto A, Michaud M, Zhang D, Grusby MJ, von Herrath M.

Diabetes. 2009 May;58(5):1144-55. doi: 10.2337/db08-0882. Epub 2009 Feb 10.


BRG1-mediated chromatin remodeling regulates differentiation and gene expression of T helper cells.

Wurster AL, Pazin MJ.

Mol Cell Biol. 2008 Dec;28(24):7274-85. doi: 10.1128/MCB.00835-08. Epub 2008 Oct 13.


IL-21 inhibits IFN-gamma production in developing Th1 cells through the repression of Eomesodermin expression.

Suto A, Wurster AL, Reiner SL, Grusby MJ.

J Immunol. 2006 Sep 15;177(6):3721-7.


NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression.

Mehta DS, Wurster AL, Weinmann AS, Grusby MJ.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2016-21. Epub 2005 Jan 31.


Biology of IL-21 and the IL-21 receptor.

Mehta DS, Wurster AL, Grusby MJ.

Immunol Rev. 2004 Dec;202:84-95. Review.


IL-21 induces the apoptosis of resting and activated primary B cells.

Mehta DS, Wurster AL, Whitters MJ, Young DA, Collins M, Grusby MJ.

J Immunol. 2003 Apr 15;170(8):4111-8.


Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells.

Wurster AL, Rodgers VL, Satoskar AR, Whitters MJ, Young DA, Collins M, Grusby MJ.

J Exp Med. 2002 Oct 7;196(7):969-77.


A mouse strain defective for alphabeta versus gammadelta T cell lineage commitment.

Mertsching E, Wurster AL, Katayama C, Esko J, Ramsdell F, Marth JD, Hedrick SM.

Int Immunol. 2002 Sep;14(9):1039-53.


Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL.

Wurster AL, Rodgers VL, White MF, Rothstein TL, Grusby MJ.

J Biol Chem. 2002 Jul 26;277(30):27169-75. Epub 2002 May 22.


IL-21 limits NK cell responses and promotes antigen-specific T cell activation: a mediator of the transition from innate to adaptive immunity.

Kasaian MT, Whitters MJ, Carter LL, Lowe LD, Jussif JM, Deng B, Johnson KA, Witek JS, Senices M, Konz RF, Wurster AL, Donaldson DD, Collins M, Young DA, Grusby MJ.

Immunity. 2002 Apr;16(4):559-69.


The biology of Stat4 and Stat6.

Wurster AL, Tanaka T, Grusby MJ.

Oncogene. 2000 May 15;19(21):2577-84. Review.


Stat6-dependent and -independent pathways for IL-4 production.

Kaplan MH, Wurster AL, Smiley ST, Grusby MJ.

J Immunol. 1999 Dec 15;163(12):6536-40.


Elf-1 binds to a critical element in a second CD4 enhancer.

Wurster AL, Siu G, Leiden JM, Hedrick SM.

Mol Cell Biol. 1994 Oct;14(10):6452-63. Erratum in: Mol Cell Biol 1994 Dec;14(12):8493.


A transcriptional silencer controls the developmental expression of the CD4 gene.

Siu G, Wurster AL, Duncan DD, Soliman TM, Hedrick SM.

EMBO J. 1994 Aug 1;13(15):3570-9.


Expression of the CD4 gene requires a Myb transcription factor.

Siu G, Wurster AL, Lipsick JS, Hedrick SM.

Mol Cell Biol. 1992 Apr;12(4):1592-604.

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